Publications by authors named "Mark J Dunne"

35Publications

Corrigendum: Efficacy of Dose-Titrated Glucagon Infusions in the Management of Congenital Hyperinsulinism: A Case Series.

Front Endocrinol (Lausanne) 2020 16;11:614734. Epub 2020 Nov 16.

Department of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, United Kingdom.

View Article and Find Full Text PDF
November 2020

Efficacy of Dose-Titrated Glucagon Infusions in the Management of Congenital Hyperinsulinism: A Case Series.

Front Endocrinol (Lausanne) 2020 3;11:441. Epub 2020 Sep 3.

Department of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, United Kingdom.

View Article and Find Full Text PDF
September 2020

Case report: contradictory genetics and imaging in focal congenital hyperinsulinism reinforces the need for pancreatic biopsy.

Int J Pediatr Endocrinol 2020 31;2020:17. Epub 2020 Aug 31.

Department of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, M13 9WL UK.

View Article and Find Full Text PDF
August 2020

Unravelling the genetic causes of mosaic islet morphology in congenital hyperinsulinism.

J Pathol Clin Res 2020 01 29;6(1):12-16. Epub 2019 Oct 29.

Molecular Genetics, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK.

View Article and Find Full Text PDF
January 2020

Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism.

PLoS One 2019 16;14(9):e0222350. Epub 2019 Sep 16.

Faculty of Biology Medicine and Health, School of Medicine, Division of Diabetes Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom.

View Article and Find Full Text PDF
March 2020

Focal Congenital Hyperinsulinism as a Cause for Sudden Infant Death.

Pediatr Dev Pathol 2019 Jan-Feb;22(1):65-69. Epub 2018 Mar 20.

4 Department of Paediatric Histopathology, St Mary's Hospital, Manchester, UK.

View Article and Find Full Text PDF
March 2019

Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.

Cancer Res 2017 09 18;77(18):4921-4933. Epub 2017 Jul 18.

Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.

View Article and Find Full Text PDF
September 2017

Functional and Metabolomic Consequences of K Channel Inactivation in Human Islets.

Diabetes 2017 07 25;66(7):1901-1913. Epub 2017 Apr 25.

Division of Endocrinology and Diabetes, Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

View Article and Find Full Text PDF
July 2017

Extreme caution on the use of sirolimus for the congenital hyperinsulinism in infancy patient.

Orphanet J Rare Dis 2017 04 14;12(1):70. Epub 2017 Apr 14.

Paediatric Endocrinology, Central Manchester University Hospitals NHS Foundation Trust (CMFT) and The University of Manchester, Oxford Road, Manchester, M13 9PT, UK.

View Article and Find Full Text PDF
April 2017

mTOR Inhibitors for the Treatment of Severe Congenital Hyperinsulinism: Perspectives on Limited Therapeutic Success.

J Clin Endocrinol Metab 2016 12 3;101(12):4719-4729. Epub 2016 Oct 3.

Department of Pediatrics (M.S.), Centre Hospitalier Universitaire Estaing, 63003 Clermont-Ferrand Cedex 1, France; Department of Pediatric Endocrinology (M.S.E., R.P., I.B.), Royal Manchester Children's Hospital, Manchester M13 9WL, United Kingdom; Faculty of Life Science (B.H., K.M., A.S., M.J.D.), University of Manchester, Manchester M13 9PL, United Kingdom; Department of Pediatrics (L.D., F.P.-L.B., E.L.), Sud Hospital, 35203 Rennes, France; Department of Pediatrics (R.R., C.F.), Timone Hospital, 13385 Marseille Cedex 5, France; Metabolism Unit (C.B., P.d.L., J.-B.A.), Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, 75743 Paris Cedex 15, France; Imagine-Genetic Disease Institute (P.d.L.), 75015 Paris, France; Paris Descartes University (P.d.L.), 75270 Paris, France; and Department of Genetics (C.S.-M.), Assistance Publique-Hôpitaux de Paris Groupe Hospitalier Pitié-Salpêtrière, Pierre et Marie Curie University, 75013 Paris Cedex 13, France.

View Article and Find Full Text PDF
December 2016

Feeding Problems Are Persistent in Children with Severe Congenital Hyperinsulinism.

Front Endocrinol (Lausanne) 2016 9;7. Epub 2016 Feb 9.

Department of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, UK; Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK.

View Article and Find Full Text PDF
February 2016

Altered Phenotype of β-Cells and Other Pancreatic Cell Lineages in Patients With Diffuse Congenital Hyperinsulinism in Infancy Caused by Mutations in the ATP-Sensitive K-Channel.

Diabetes 2015 Sep 30;64(9):3182-8. Epub 2015 Apr 30.

Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, U.K. Department of Endocrinology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, U.K.

View Article and Find Full Text PDF
September 2015

Reduced Glycemic Variability in Diazoxide-Responsive Children with Congenital Hyperinsulinism Using Supplemental Omega-3-Polyunsaturated Fatty Acids; A Pilot Trial with MaxEPA(R.).

Front Endocrinol (Lausanne) 2014 12;5:31. Epub 2014 Mar 12.

Department of Paediatric Endocrinology, Manchester Academic Health Science Centre, Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust , Manchester , UK ; Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester , Manchester , UK.

View Article and Find Full Text PDF
March 2014