Mark J Arends

Mark J Arends

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Mark J Arends

Publications by authors named "Mark J Arends"

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Update on the pathology, genetics and somatic landscape of sebaceous tumours.

Histopathology 2019 Dec 10. Epub 2019 Dec 10.

Department of Pathology & Laboratory Medicine, The Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1111/his.14044DOI Listing
December 2019

Survey of UK histopathology consultants' attitudes towards academic and molecular pathology.

J Clin Pathol 2019 Jun 25;72(6):399-405. Epub 2019 Mar 25.

Academic Unit of Oral and Maxillofacial Medicine, Pathology and Surgery, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1136/jclinpath-2018-205568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580784PMC
June 2019

Pulmonary metastatic colonisation and granulomas in NOX2-deficient mice.

J Pathol 2018 11 19;246(3):300-310. Epub 2018 Sep 19.

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1002/path.5140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221033PMC
November 2018

Mutational Analysis Identifies Therapeutic Biomarkers in Inflammatory Bowel Disease-Associated Colorectal Cancers.

Clin Cancer Res 2018 10 27;24(20):5133-5142. Epub 2018 Jun 27.

Division of Pathology, Centre for Comparative Pathology, Edinburgh Cancer Research Centre, Institute of Genetics & Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-3713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193541PMC
October 2018

Lynch syndrome - cancer pathways, heterogeneity and immune escape.

J Pathol 2018 10 27;246(2):129-133. Epub 2018 Aug 27.

Institute of Medical Genetics, University Hospital of Wales, Cardiff, UK.

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http://dx.doi.org/10.1002/path.5139DOI Listing
October 2018

DNA mismatch repair and CD133-marked cancer stem cells in colorectal carcinoma.

PeerJ 2018 11;6:e5530. Epub 2018 Sep 11.

Division of Pathology, Edinburgh Cancer Research Centre, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.7717/peerj.5530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138039PMC
September 2018

Widespread spontaneous hyperproliferation, melanosis and melanoma in Hgf-Cdk4R24C mice.

Melanoma Res 2018 02;28(1):76-78

Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge.

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http://dx.doi.org/10.1097/CMR.0000000000000414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739287PMC
February 2018

Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations.

BMC Cancer 2018 01 3;18(1):16. Epub 2018 Jan 3.

Nicola Murray Centre for Ovarian Cancer Research, Edinburgh Cancer Research UK Centre, MRC IGMM, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK.

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https://bmccancer.biomedcentral.com/articles/10.1186/s12885-
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http://dx.doi.org/10.1186/s12885-017-3981-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753521PMC
January 2018

A high-throughput in vivo screening method in the mouse for identifying regulators of metastatic colonization.

Nat Protoc 2017 Dec 2;12(12):2465-2477. Epub 2017 Nov 2.

Experimental Cancer Genetics Group, Wellcome Trust Sanger Institute, Hinxton, UK.

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http://dx.doi.org/10.1038/nprot.2017.118DOI Listing
December 2017

Complement Factor B Is a Determinant of Both Metabolic and Cardiovascular Features of Metabolic Syndrome.

Hypertension 2017 Jul 24. Epub 2017 Jul 24.

From the Centre for Genomic and Experimental Medicine, MRC Institute for Genetics and Molecular Medicine, Edinburgh, United Kingdom (P.M.C., M.B., N.A., S.M.P., X.C.D., D.R., J.M., T.J.A.); British Heart Foundation Centre for Cardiovascular Science, Queen's Medical Research Institute (P.M.C., M.B., N.A., R.N.C., A.T., L.H.J.-J., N.M.M., T.J.A.) and Royal (Dick) School of Veterinary Studies (X.C.D.), University of Edinburgh, United Kingdom; Department of Medicine (A.G.D., T.J.A) and Embryonic Stem Cell and Transgenics Facility, MRC Clinical Sciences Centre (B.M., Z.W.), Imperial College London, United Kingdom; and Division of Pathology, Centre for Comparative Pathology, Cancer Research UK Edinburgh Centre, United Kingdom (M.J.A.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548512PMC
July 2017

Effects of long-term ethanol consumption and Aldh1b1 depletion on intestinal tumourigenesis in mice.

J Pathol 2017 04 7;241(5):649-660. Epub 2017 Mar 7.

University of Edinburgh, Division of Pathology, Centre for Comparative Pathology, Cancer Research UK Edinburgh Centre, Institute of Genetics & Molecular Medicine, Western General Hospital, Crewe Road South, Edinburgh, EH4 2XR, UK.

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http://dx.doi.org/10.1002/path.4869DOI Listing
April 2017

New concepts for an old problem: the diagnosis of endometrial hyperplasia.

Hum Reprod Update 2017 03;23(2):232-254

MRC Centre for Inflammation Research, The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, EdinburghEH16 4TJ, UK.

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https://academic.oup.com/humupd/article-lookup/doi/10.1093/h
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http://dx.doi.org/10.1093/humupd/dmw042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850217PMC
March 2017

PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation.

Mol Cell 2017 Mar;65(6):999-1013.e7

Signalling and Cancer Metabolism Team, Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London SW7 2AZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426642PMC
March 2017

A non-cell autonomous mouse model of CNS haemangioblastoma mediated by mutant KRAS.

Sci Rep 2017 03 21;7:44899. Epub 2017 Mar 21.

Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, University of Oxford, Oxford, OX3 9DS, UK.

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http://dx.doi.org/10.1038/srep44899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359595PMC
March 2017

Molecular pathological classification of colorectal cancer.

Virchows Arch 2016 Aug 20;469(2):125-34. Epub 2016 Jun 20.

Division of Pathology, Centre for Comparative Pathology, Edinburgh Cancer Research Centre, Institute of Genetics & Molecular Medicine, Western General Hospital, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XR, UK.

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http://dx.doi.org/10.1007/s00428-016-1956-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978761PMC
August 2016

Familial Adrenocortical Carcinoma in Association With Lynch Syndrome.

J Clin Endocrinol Metab 2016 Jun 4;101(6):2269-72. Epub 2016 May 4.

Metabolic Research Laboratories (B.G.C., N.K., A.S.P., O.K., A.K.A., M.G.), Wellcome Trust-MRC Institute of Metabolic Science, and Departments of Histopathology (L.H., A.J.M.) and Medical Genetics (S.N.-Z.), University of Cambridge and National Institute for Health Research Cambridge Biomedical Research Centre, Addenbrooke's Hospital, Cambridge, UK CB2 0QQ; Division of Pathology (M.J.A.), University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1210/jc.2016-1460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891804PMC
June 2016

Multilocus Inherited Neoplasia Alleles Syndrome: A Case Series and Review.

JAMA Oncol 2016 Mar;2(3):373-9

Department of Medical Genetics, University of Cambridge and Cambridge NIHR Biomedical Research Centre, Cambridge, England.

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http://dx.doi.org/10.1001/jamaoncol.2015.4771DOI Listing
March 2016

Cross-species models of human melanoma.

J Pathol 2016 Jan 9;238(2):152-65. Epub 2015 Oct 9.

Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.

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http://dx.doi.org/10.1002/path.4632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832391PMC
January 2016

Animal and cellular models of human disease.

J Pathol 2016 Jan;238(2):137-40

The Roslin Institute, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1002/path.4662DOI Listing
January 2016

Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.

Mol Cell 2015 Oct 24;60(1):177-88. Epub 2015 Sep 24.

MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 2QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.08.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595711PMC
October 2015

Mouse models of colorectal cancer as preclinical models.

Bioessays 2015 Aug 26;37(8):909-20. Epub 2015 Jun 26.

Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1002/bies.201500032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755199PMC
August 2015

Signatures of adaptation in human invasive Salmonella Typhimurium ST313 populations from sub-Saharan Africa.

PLoS Negl Trop Dis 2015 Mar 24;9(3):e0003611. Epub 2015 Mar 24.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom; Institute of Food Research, Norwich Research Park, Norwich, Norfolk, United Kingdom.

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http://dx.doi.org/10.1371/journal.pntd.0003611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372345PMC
March 2015

Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia.

Exp Hematol 2014 Dec 12;42(12):1053-8.e1. Epub 2014 Aug 12.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2014.07.269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271779PMC
December 2014

Versatile and enhanced tumour modelling in mice via somatic cell transduction.

J Pathol 2014 Mar;232(4):449-57

Department of Molecular Imaging, CRUK Cambridge Institute, University of Cambridge, UK.

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http://dx.doi.org/10.1002/path.4313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288983PMC
March 2014

Wild-type K-ras has a tumour suppressor effect on carcinogen-induced murine colorectal adenoma formation.

Int J Exp Pathol 2014 Feb 20;95(1):8-15. Epub 2013 Dec 20.

Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1111/iep.12064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919644PMC
February 2014

IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer.

Int J Exp Pathol 2013 Jun 18;94(3):203-11. Epub 2013 Apr 18.

MRC Laboratory of Molecular Biology, Cambridge, UK.

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http://dx.doi.org/10.1111/iep.12021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664965PMC
June 2013

Pathways of colorectal carcinogenesis.

Authors:
Mark J Arends

Appl Immunohistochem Mol Morphol 2013 Mar;21(2):97-102

Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1097/PAI.0b013e31827ea79eDOI Listing
March 2013

Generation of the Sotos syndrome deletion in mice.

Mamm Genome 2012 Dec 29;23(11-12):749-57. Epub 2012 Aug 29.

Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, UK.

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http://dx.doi.org/10.1007/s00335-012-9416-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510424PMC
December 2012

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.

Nature 2012 Sep 26;489(7417):571-5. Epub 2012 Aug 26.

MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

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http://www.nature.com/articles/nature11368
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http://dx.doi.org/10.1038/nature11368DOI Listing
September 2012

Loss of RASSF1A synergizes with deregulated RUNX2 signaling in tumorigenesis.

Cancer Res 2012 Aug 18;72(15):3817-3827. Epub 2012 Jun 18.

Gray Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067151PMC
August 2012

Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1.

Mol Cancer 2012 May 3;11:29. Epub 2012 May 3.

Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1HH, UK.

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http://dx.doi.org/10.1186/1476-4598-11-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489691PMC
May 2012

RAS signalling in the colorectum in health and disease.

Cell Commun Adhes 2012 Feb 10;19(1):1-9. Epub 2012 Jan 10.

Department of Systems Biology, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.

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http://dx.doi.org/10.3109/15419061.2011.649380DOI Listing
February 2012

Synergism between K-rasVal12 and mutant Apc accelerates murine large intestinal tumourigenesis.

Oncol Rep 2011 Jul 29;26(1):125-33. Epub 2011 Apr 29.

Department of Pathology, Addenbrooke's Hospital, University of Cambridge, Hills Road, Cambridge, CB2 0QQ, UK.

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http://dx.doi.org/10.3892/or.2011.1288DOI Listing
July 2011

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

Nature 2011 Jul 6;475(7354):53-8. Epub 2011 Jul 6.

MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

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http://dx.doi.org/10.1038/nature10192DOI Listing
July 2011

Activation of mutated K-ras in donor endometrial epithelium and stroma promotes lesion growth in an intact immunocompetent murine model of endometriosis.

J Pathol 2011 Jun 11;224(2):261-9. Epub 2011 Apr 11.

Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.

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http://dx.doi.org/10.1002/path.2852DOI Listing
June 2011

Acute sensitivity of the oral mucosa to oncogenic K-ras.

J Pathol 2011 May 7;224(1):22-32. Epub 2011 Mar 7.

Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK.

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http://dx.doi.org/10.1002/path.2853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627303PMC
May 2011

Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression.

Gut 2011 Apr 10;60(4):499-508. Epub 2010 Nov 10.

Department of Pathology, Division of Molecular Histopathology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, UK.

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http://dx.doi.org/10.1136/gut.2010.223602DOI Listing
April 2011

Activation of K-RAS by co-mutation of codons 19 and 20 is transforming.

J Mol Signal 2011 Mar 3;6. Epub 2011 Mar 3.

Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK, CB2 0QQ, UK.

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http://dx.doi.org/10.1186/1750-2187-6-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056876PMC
March 2011

Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability.

J Pathol 2011 Feb 11;223(3):390-9. Epub 2010 Nov 11.

Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK.

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http://dx.doi.org/10.1002/path.2790DOI Listing
February 2011

Lifestyle factors and p53 mutation patterns in colorectal cancer patients in the EPIC-Norfolk study.

Mutagenesis 2010 Jul 12;25(4):351-8. Epub 2010 Mar 12.

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1093/mutage/geq012DOI Listing
July 2010

K-ras exon 4A has a tumour suppressor effect on carcinogen-induced murine colonic adenoma formation.

J Pathol 2010 Apr;220(5):542-50

Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.

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http://dx.doi.org/10.1002/path.2672DOI Listing
April 2010

Prognostic relevance of DNA copy number changes in colorectal cancer.

J Pathol 2010 Feb;220(3):338-47

Department of Pathology, University of Cambridge, Cambridge, UK.

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http://doi.wiley.com/10.1002/path.2640
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http://dx.doi.org/10.1002/path.2640DOI Listing
February 2010

DNA mismatch repair deficiency in sporadic colorectal cancer and Lynch syndrome.

Histopathology 2010 Jan;56(2):167-79

Department of Pathology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/j.1365-2559.2009.03392.xDOI Listing
January 2010

Megaoesophagus in Rassf1a-null mice.

Int J Exp Pathol 2009 Apr;90(2):101-8

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1111/j.1365-2613.2008.00635.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676702PMC
April 2009

The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the ApcMin/+ mouse small intestine.

BMC Gastroenterol 2008 Jun 13;8:24. Epub 2008 Jun 13.

Sir Alastair Currie Cancer Research UK Laboratories, Molecular Medicine Centre, The University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK.

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http://bmcgastroenterol.biomedcentral.com/articles/10.1186/1
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http://dx.doi.org/10.1186/1471-230X-8-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442095PMC
June 2008

Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis.

Exp Cell Res 2008 Mar 17;314(5):1105-14. Epub 2007 Nov 17.

Sir Alastair Currie Cancer Research UK Laboratories, Molecular Medicine Centre, The University of Edinburgh, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.yexcr.2007.11.004DOI Listing
March 2008

Stem cell gene expression changes induced specifically by mutated K-ras.

Gene Expr 2007 ;14(2):101-15

Department of Pathology, Addenbrooke's Hospital, Hills Road, University of Cambridge, Cambridge CB2 2QQ, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042043PMC
http://dx.doi.org/10.3727/105221607783417583DOI Listing
March 2008

MMASS: an optimized array-based method for assessing CpG island methylation.

Nucleic Acids Res 2006 13;34(20):e136. Epub 2006 Oct 13.

Department of Pathology, Division of Molecular Histopathology, Addenbrooke's Hospital Hills Road, Cambridge CB2 2XZ, UK.

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http://dx.doi.org/10.1093/nar/gkl551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635254PMC
December 2006

Renin enhancer is critical for control of renin gene expression and cardiovascular function.

J Biol Chem 2006 Oct 8;281(42):31753-61. Epub 2006 Aug 8.

School of Medical Sciences and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia.

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http://dx.doi.org/10.1074/jbc.M605720200DOI Listing
October 2006

The K-Ras 4A isoform promotes apoptosis but does not affect either lifespan or spontaneous tumor incidence in aging mice.

Exp Cell Res 2006 Jan 4;312(1):16-26. Epub 2005 Nov 4.

Sir Alastair Currie Cancer Research UK Laboratories, Molecular Medicine Centre, The University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1016/j.yexcr.2005.10.004DOI Listing
January 2006

Null and conditional semaphorin 3B alleles using a flexible puroDeltatk loxP/FRT vector.

Genesis 2005 Apr;41(4):171-8

Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.

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http://dx.doi.org/10.1002/gene.20111DOI Listing
April 2005

Multiple mucinous tumours.

Pathology 2005 Feb;37(1):91-2

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http://dx.doi.org/10.1080/00313020400023479DOI Listing
February 2005

Potency of arachidonic acid in polyunsaturated fatty acid-induced death of human monocyte-macrophages: implications for atherosclerosis.

Prostaglandins Leukot Essent Fatty Acids 2004 Oct;71(4):251-62

Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.

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http://dx.doi.org/10.1016/j.plefa.2004.03.020DOI Listing
October 2004

K-ras proto-oncogene exhibits tumor suppressor activity as its absence promotes tumorigenesis in murine teratomas.

Mol Cancer Res 2003 Sep;1(11):820-5

Sir Alastair Currie Cancer Research UK Laboratories, Molecular Medicine Centre, The University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.

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September 2003

Heterozygosity for p53 promotes microsatellite instability and tumorigenesis on a Msh2 deficient background.

Oncogene 2002 Sep;21(41):6299-306

Department of Pathology, University Medical School, Teviot Place, Edinburgh EH8 9AG, UK.

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http://dx.doi.org/10.1038/sj.onc.1205727DOI Listing
September 2002

Carotenoids induce apoptosis in the T-lymphoblast cell line Jurkat E6.1.

Free Radic Res 2002 Jul;36(7):791-802

Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.

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http://dx.doi.org/10.1080/10715760290032539DOI Listing
July 2002