Mark Girvin

Department of Biochemistry, ‡Departments of Neurology and Neuroscience, and §Department of Genetics, Albert Einstein College of Medicine , 1300 Morris Park Avenue, Bronx, New York 10461, United States.

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August 2016

Structural and Functional Studies on the Marburg Virus GP2 Fusion Loop.

Authors:

Nina Liu Yisong Tao Michael D Brenowitz Mark E Girvin Jonathan R Lai

J Infect Dis 2015 Oct 18;212 Suppl 2:S146-53. Epub 2015 Mar 18.

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York.

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October 2015

Conditional trimerization and lytic activity of HIV-1 gp41 variants containing the membrane-associated segments.

Authors:

Zhou Dai Yisong Tao Nina Liu Michael D Brenowitz Mark E Girvin Jonathan R Lai

Biochemistry 2015 Mar 13;54(8):1589-99. Epub 2015 Feb 13.

Department of Biochemistry, Albert Einstein College of Medicine , 1300 Morris Park Avenue, Bronx, New York 10461, United States.

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March 2015

Controlling lipid micelle stability using oligonucleotide headgroups.

Authors:

Samantha E Wilner Samuel E Sparks David Cowburn Mark E Girvin Matthew Levy

J Am Chem Soc 2015 Feb 3;137(6):2171-4. Epub 2015 Feb 3.

Department of Biochemistry, Albert Einstein College of Medicine , Bronx, New York 10461, United States.

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February 2015

An RNA aptamer possessing a novel monovalent cation-mediated fold inhibits lysozyme catalysis by inhibiting the binding of long natural substrates.

Authors:

Camille S Padlan Vladimir N Malashkevich Steve C Almo Matthew Levy Michael Brenowitz Mark E Girvin

RNA 2014 Apr 25;20(4):447-61. Epub 2014 Feb 25.

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April 2014

Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids.

Authors:

Lauren K Regula Richard Harris Fang Wang Chelsea D Higgins Jayne F Koellhoffer Yue Zhao Kartik Chandran Jianmin Gao Mark E Girvin Jonathan R Lai

Biochemistry 2013 May 7;52(20):3393-404. Epub 2013 May 7.

Department of Biochemistry and ‡Department of Microbiology and Immunology, Albert Einstein College of Medicine , 1300 Morris Park Avenue, Bronx, New York 10461, United States.

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May 2013

Backbone ¹H, ¹³C, ¹⁵N NMR assignments of yeast OMP synthase in unliganded form and in complex with orotidine 5'-monophosphate.

Authors:

Michael Riis Hansen Richard Harris Eric W Barr Hong Cheng Mark E Girvin Charles Grubmeyer

Biomol NMR Assign 2014 Apr 12;8(1):103-8. Epub 2013 Jan 12.

Department of Biochemistry, Temple University School of Medicine, 3307 N Broad St., Philadelphia, PA, 19140, USA.

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April 2014

Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control.

Authors:

Vivek L Patel Somdeb Mitra Richard Harris Adina R Buxbaum Timothée Lionnet Michael Brenowitz Mark Girvin Matthew Levy Steven C Almo Robert H Singer Jeffrey A Chao

Genes Dev 2012 Jan;26(1):43-53

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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January 2012

Activated ERK2 is a monomer in vitro with or without divalent cations and when complexed to the cytoplasmic scaffold PEA-15.

Authors:

Tamer S Kaoud Ashwini K Devkota Richard Harris Mitra S Rana Olga Abramczyk Mangalika Warthaka Sunbae Lee Mark E Girvin Austen F Riggs Kevin N Dalby

Biochemistry 2011 May 4;50(21):4568-78. Epub 2011 May 4.

Division of Medicinal Chemistry, University of Texas, Austin, TX 78712, USA.

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May 2011

Backbone 1H, 13C, 15N NMR assignments of the unliganded and substrate ternary complex forms of mevalonate diphosphate decarboxylase from Streptococcus pneumoniae.

Authors:

Guido Reuther Richard Harris Mark Girvin Thomas S Leyh

Biomol NMR Assign 2011 Apr 25;5(1):11-4. Epub 2010 Aug 25.

Department of Microbiology and Immunology, Albert-Einstein-College of Medicine of Yeshiva University, Bronx, NY 10461-1926, USA.

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April 2011

The New York Consortium on Membrane Protein Structure (NYCOMPS): a high-throughput platform for structural genomics of integral membrane proteins.

Authors:

James Love Filippo Mancia Lawrence Shapiro Marco Punta Burkhard Rost Mark Girvin Da-Neng Wang Ming Zhou John F Hunt Thomas Szyperski Eric Gouaux Roderick MacKinnon Ann McDermott Barry Honig Masayori Inouye Gaetano Montelione Wayne A Hendrickson

J Struct Funct Genomics 2010 Sep 6;11(3):191-9. Epub 2010 Aug 6.

New York Structural Biology Center, New York, 10027, USA.

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September 2010

1H, 13C, 15N backbone NMR assignments of the Staphylococcus aureus small multidrug-resistance pump (Smr) in a functionally active conformation.

Authors:

Sébastien F Poget Richard Harris Sean M Cahill Mark E Girvin

Biomol NMR Assign 2010 Oct 21;4(2):139-42. Epub 2010 Apr 21.

Chemistry Department, College of Staten Island, 2800 Victory Boulevard, Staten Island, NY 10314, USA.

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October 2010

Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110alpha and are disrupted in oncogenic p85 mutants.

Authors:

Haiyan Wu S Chandra Shekar Rory J Flinn Mirvat El-Sibai Bijay S Jaiswal K Ilker Sen Vasantharajan Janakiraman Somasekar Seshagiri Gary J Gerfen Mark E Girvin Jonathan M Backer

Proc Natl Acad Sci U S A 2009 Dec 13;106(48):20258-63. Epub 2009 Nov 13.

Department of Molecular Pharmacology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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December 2009

Unique opportunities for NMR methods in structural genomics.

Authors:

Gaetano T Montelione Cheryl Arrowsmith Mark E Girvin Michael A Kennedy John L Markley Robert Powers James H Prestegard Thomas Szyperski

J Struct Funct Genomics 2009 Apr 15;10(2):101-6. Epub 2009 Mar 15.

Center for Advanced Biotechnology and Medicine, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA.

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April 2009

High-resolution NMR characterization of a spider-silk mimetic composed of 15 tandem repeats and a CRGD motif.

Authors:

Glendon D McLachlan Joseph Slocik Robert Mantz David Kaplan Sean Cahill Mark Girvin Steve Greenbaum

Protein Sci 2009 Jan;18(1):206-16

Department of Physics and Astronomy Hunter College, City University of New York, New York, NY 10065, USA.

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January 2009

Effectively doubling the magnetic field in spin-1/2-spin-1, HSQC, HDQC, coupled HSQC, and coupled HDQC in solution NMR.

Authors:

S Chandra Shekar Jonathan M Backer Mark E Girvin

J Chem Phys 2008 May;128(18):184501

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Yeshiva University, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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May 2008

GFT projection NMR based resonance assignment of membrane proteins: application to subunit C of E. coli F(1)F (0) ATP synthase in LPPG micelles.

Authors:

Qi Zhang Hanudatta S Atreya Douglas E Kamen Mark E Girvin Thomas Szyperski

J Biomol NMR 2008 Mar 14;40(3):157-63. Epub 2008 Feb 14.

Department of Chemistry, State University of New York at Buffalo, Buffalo, NY 14260, USA.

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March 2008

Solution NMR of membrane proteins in bilayer mimics: small is beautiful, but sometimes bigger is better.

Authors:

Sébastien F Poget Mark E Girvin

Biochim Biophys Acta 2007 Dec 20;1768(12):3098-106. Epub 2007 Sep 20.

Biochemistry Department, Albert Einstein College of Medicine, 1300 Morris Park Ave. Bronx, NY 10461, USA.

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December 2007

Acid-induced equilibrium folding intermediate of human platelet profilin.

Authors:

Glendon D McLachlan Sean M Cahill Mark E Girvin Steven C Almo

Biochemistry 2007 Jun 19;46(23):6931-43. Epub 2007 May 19.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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June 2007

Isotropic bicelles stabilize the functional form of a small multidrug-resistance pump for NMR structural studies.

Authors:

Sébastien F Poget Sean M Cahill Mark E Girvin

J Am Chem Soc 2007 Mar 7;129(9):2432-3. Epub 2007 Feb 7.

Biochemistry Department, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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March 2007

Multiple alignment of membrane proteins for measuring residual dipolar couplings using lanthanide ions bound to a small metal chelator.

Authors:

Douglas E Kamen Sean M Cahill Mark E Girvin

J Am Chem Soc 2007 Feb 25;129(7):1846-7. Epub 2007 Jan 25.

Biochemistry Department, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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February 2007

NMR assignment of the dimeric S. aureus small multidrug-resistance pump in LPPG micelles.

Authors:

Sébastien F Poget Suzanne T Krueger-Koplin Ray D Krueger-Koplin Sean M Cahill S Chandra Shekar Mark E Girvin

J Biomol NMR 2006 ;36 Suppl 1:10

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10469, USA.

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August 2007

Mechanism of constitutive phosphoinositide 3-kinase activation by oncogenic mutants of the p85 regulatory subunit.

Authors:

S Chandra Shekar Haiyan Wu Zheng Fu Shu-Chin Yip Nagajyothi Sean M Cahill Mark E Girvin Jonathan M Backer

J Biol Chem 2005 Jul 2;280(30):27850-5. Epub 2005 Jun 2.

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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July 2005

Structural basis for the physiological temperature dependence of the association of VP16 with the cytoplasmic tail of herpes simplex virus glycoprotein H.

Authors:

Douglas E Kamen Sarah T Gross Mark E Girvin Duncan W Wilson

J Virol 2005 May;79(10):6134-41

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, New York, NY 10461, USA.

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May 2005

pKa of the essential Glu54 and backbone conformation for subunit c from the H+-coupled F1F0 ATP synthase from an alkaliphilic Bacillus.

Authors:

Iván O Rivera-Torres Ray D Krueger-Koplin David B Hicks Sean M Cahill Terry A Krulwich Mark E Girvin

FEBS Lett 2004 Sep;575(1-3):131-5

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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September 2004

Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.

Authors:

Hua Deng Andrzej Lewandowicz Sean M Cahill Richard H Furneaux Peter C Tyler Mark E Girvin Robert H Callender Vern L Schramm

Biochemistry 2004 Feb;43(7):1980-7

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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February 2004

An evaluation of detergents for NMR structural studies of membrane proteins.

Authors:

Ray D Krueger-Koplin Paul L Sorgen Suzanne T Krueger-Koplin Iván O Rivera-Torres Sean M Cahill David B Hicks Leo Grinius Terry A Krulwich Mark E Girvin

J Biomol NMR 2004 Jan;28(1):43-57

Biochemistry Department, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, U.S.A.

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January 2004

Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases.

Authors:

Anthony A Sauve Sean M Cahill Stephan G Zech Luiz A Basso Andrzej Lewandowicz Diogenes S Santos Charles Grubmeyer Gary B Evans Richard H Furneaux Peter C Tyler Ann McDermott Mark E Girvin Vern L Schramm

Biochemistry 2003 May;42(19):5694-705

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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May 2003

An approach to membrane protein structure without crystals.

Authors:

Paul L Sorgen Yonglin Hu Lan Guan H Ronald Kaback Mark E Girvin

Proc Natl Acad Sci U S A 2002 Oct 21;99(22):14037-40. Epub 2002 Oct 21.

Biochemistry Department, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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October 2002

Sequence-specific resonance assignment of the carboxyl terminal domain of Connexin43.

Authors:

Paul L Sorgen Heather S Duffy Sean M Cahill Wanda Coombs David C Spray Mario Delmar Mark E Girvin

J Biomol NMR 2002 Jul;23(3):245-6

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July 2002

pH-dependent intramolecular binding and structure involving Cx43 cytoplasmic domains.

Authors:

Heather S Duffy Paul L Sorgen Mark E Girvin Phyllis O'Donnell Wanda Coombs Steven M Taffet Mario Delmar David C Spray

J Biol Chem 2002 Sep 31;277(39):36706-14. Epub 2002 Jul 31.

Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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September 2002

Interactions of amidated acids with heparin.

Authors:

Ruel Z B Desamero Hu Cheng Sean Cahill Mark Girvin Hua Deng Robert Callender Parshuram Rath Bruce Variano John E Smart

Biopolymers 2002 ;67(1):41-8

Department of Physics, City College of New York, New York, New York 10031, USA.

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April 2002

Physical properties of compounds promoting oral delivery of macromolecular drugs.

Authors:

Ruel Z B Desamero Hu Cheng Sean Cahill Mark Girvin Hua Deng Robert Callender Parshuram Rath Bruce Variano John E Smart

Biopolymers 2002 ;67(1):26-40

Department of Physics, City College of New York, New York, New York 10031, USA.

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April 2002

Structure of the Rhodobacter sphaeroides light-harvesting 1 beta subunit in detergent micelles.

Authors:

Paul L Sorgen Sean M Cahill Ray D Krueger-Koplin Suzanne T Krueger-Koplin Craig C Schenck Mark E Girvin

Biochemistry 2002 Jan;41(1):31-41

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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January 2002

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