Mark E Hahn

Mark E Hahn

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Mark E Hahn

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Transcriptomic analysis of Anabas testudineus and its defensive mechanisms in response to persistent organic pollutants exposure.

Sci Total Environ 2019 Jun 28;669:621-630. Epub 2019 Feb 28.

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center of Eco-Environment Sciences, Chinese Academy of Sciences, Beijing 100085, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

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http://dx.doi.org/10.1016/j.scitotenv.2019.02.440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581032PMC
June 2019

Altered lipid homeostasis in a PCB-resistant Atlantic killifish (Fundulus heteroclitus) population from New Bedford Harbor, MA, U.S.A.

Aquat Toxicol 2019 May 18;210:30-43. Epub 2019 Feb 18.

Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA; Boston University Superfund Research Program, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.aquatox.2019.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544361PMC
May 2019

Aryl hydrocarbon receptor-mediated activity of gas-phase ambient air derived from passive sampling and an in vitro bioassay.

Environ Toxicol Chem 2019 Apr 4;38(4):748-759. Epub 2019 Mar 4.

University of Rhode Island Graduate School of Oceanography, Narragansett, Rhode Island, USA.

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http://dx.doi.org/10.1002/etc.4361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467651PMC
April 2019

Evolutionary concepts can benefit both fundamental research and applied research in toxicology (A comment on Brady et al. 2017).

Authors:
Mark E Hahn

Evol Appl 2019 Feb 5;12(2):350-352. Epub 2018 Nov 5.

Biology Department Woods Hole Oceanographic Institution Woods Hole Massachusetts.

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http://dx.doi.org/10.1111/eva.12695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346646PMC
February 2019

Redox stress and signaling during vertebrate embryonic development: Regulation and responses.

Semin Cell Dev Biol 2018 08 22;80:17-28. Epub 2017 Sep 22.

Department of Environmental Health Sciences, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA; Biotechnology Training Program, University of Massachusetts, Amherst, MA 01003, USA.

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http://dx.doi.org/10.1016/j.semcdb.2017.09.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650060PMC
August 2018

Molecular adaptation to high pressure in cytochrome P450 1A and aryl hydrocarbon receptor systems of the deep-sea fish Coryphaenoides armatus.

Biochim Biophys Acta Proteins Proteom 2018 Jan 8;1866(1):155-165. Epub 2017 Jul 8.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02540, USA; Boston University Superfund Research Program, Boston University School of Public Health, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2017.06.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693637PMC
January 2018

The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo.

Redox Biol 2017 10 30;13:207-218. Epub 2017 May 30.

Department of Environmental Health Sciences, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA; Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2017.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458767PMC
October 2017

When evolution is the solution to pollution: Key principles, and lessons from rapid repeated adaptation of killifish () populations.

Evol Appl 2017 09 26;10(8):762-783. Epub 2017 Apr 26.

Atlantic Ecology Division National Health and Environmental Effects Research Laboratory Office of Research and Development US Environmental Protection Agency Narragansett RI USA.

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http://dx.doi.org/10.1111/eva.12470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680427PMC
September 2017

Sequence and functional characterization of hypoxia-inducible factors, HIF1α, HIF2αa, and HIF3α, from the estuarine fish, .

Am J Physiol Regul Integr Comp Physiol 2017 03 30;312(3):R412-R425. Epub 2016 Dec 30.

Department of Biological Sciences, University of New Orleans, New Orleans, Louisiana

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http://dx.doi.org/10.1152/ajpregu.00402.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402000PMC
March 2017

Diversity as Opportunity: Insights from 600 Million Years of AHR Evolution.

Curr Opin Toxicol 2017 Feb 16;2:58-71. Epub 2017 Feb 16.

Biology Department, Rhode Island College, 600 Mt. Pleasant Avenue, 251 Fogarty Life Sciences, Providence, RI 02908.

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http://dx.doi.org/10.1016/j.cotox.2017.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343764PMC
February 2017

Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner.

Biochem Pharmacol 2016 06 22;110-111:117-29. Epub 2016 Apr 22.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543-1050, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2016.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887394PMC
June 2016

Delayed effects of developmental exposure to low levels of the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB126) on adult zebrafish behavior.

Neurotoxicology 2016 Jan 23;52:134-43. Epub 2015 Nov 23.

Biology Department and Woods Hole Center for Oceans and Human Health, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuro.2015.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753093PMC
January 2016

Nrf2 and Nrf2-related proteins in development and developmental toxicity: Insights from studies in zebrafish (Danio rerio).

Free Radic Biol Med 2015 Nov 28;88(Pt B):275-289. Epub 2015 Jun 28.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, United States of America.

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https://linkinghub.elsevier.com/retrieve/pii/S08915849150029
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http://dx.doi.org/10.1016/j.freeradbiomed.2015.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698826PMC
November 2015

Regulation of Ahr signaling by Nrf2 during development: Effects of Nrf2a deficiency on PCB126 embryotoxicity in zebrafish (Danio rerio).

Aquat Toxicol 2015 Oct 13;167:157-71. Epub 2015 Aug 13.

Department of Environmental Health Sciences, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA 01003, United States; Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, United States. Electronic address:

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http://dx.doi.org/10.1016/j.aquatox.2015.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703126PMC
October 2015

Naturally occurring marine brominated indoles are aryl hydrocarbon receptor ligands/agonists.

Chem Res Toxicol 2015 Jun 2;28(6):1176-85. Epub 2015 Jun 2.

†Department of Environmental Toxicology, University of California, Davis, California 95616, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.5b00003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469569PMC
June 2015

Targeted mutagenesis of aryl hydrocarbon receptor 2a and 2b genes in Atlantic killifish (Fundulus heteroclitus).

Aquat Toxicol 2015 Jan 26;158:192-201. Epub 2014 Nov 26.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA; Superfund Research Program, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.aquatox.2014.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272816PMC
January 2015

In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo.

Mol Pharmacol 2014 Nov 26;86(5):593-608. Epub 2014 Aug 26.

Molecular Medicine Program, Boston University School of Medicine, Boston, Massachusetts (A.J.P., E.A.S., O.N.); Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts (A.J.P., E.A.S., O.N., S.N., J.J.S., DHS); Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts (M.P.P., T.G.H.); Department of Chemistry, Boston University (T.D.A.); Biology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts (M.E.H., D.G.F.); Wake Forest Innovations, Wake Forest University, Winston-Salem, North Carolina (S.E.H.); and Biomedical Engineering, Boston University, Boston, Massachusetts (D.K., D.B., S.V.)

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http://dx.doi.org/10.1124/mol.114.093369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201140PMC
November 2014

Developmental exposure to valproic acid alters the expression of microRNAs involved in neurodevelopment in zebrafish.

Neurotoxicol Teratol 2013 Nov-Dec;40:46-58. Epub 2013 Oct 12.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ntt.2013.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895482PMC
July 2014

Developmental expression of the Nfe2-related factor (Nrf) transcription factor family in the zebrafish, Danio rerio.

PLoS One 2013 24;8(10):e79574. Epub 2013 Oct 24.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, United States of America ; Biology Department, Bates College, Lewiston, Maine, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079574PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840143PMC
June 2014

Knockdown of a zebrafish aryl hydrocarbon receptor repressor (AHRRa) affects expression of genes related to photoreceptor development and hematopoiesis.

Toxicol Sci 2014 Jun 27;139(2):381-95. Epub 2014 Mar 27.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts 02543.

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http://dx.doi.org/10.1093/toxsci/kfu052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031623PMC
June 2014

Species-specific relative AHR1 binding affinities of 2,3,4,7,8-pentachlorodibenzofuran explain avian species differences in its relative potency.

Comp Biochem Physiol C Toxicol Pharmacol 2014 Apr 13;161:21-5. Epub 2014 Jan 13.

Centre for Advanced Research in Environmental Genomics, Department of Biology, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada; Environment Canada, National Wildlife Research Centre, Ottawa, Ontario K1A 0H3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cbpc.2013.12.005DOI Listing
April 2014

Glutathione redox dynamics and expression of glutathione-related genes in the developing embryo.

Free Radic Biol Med 2013 Dec 13;65:89-101. Epub 2013 Jun 13.

Division of Pulmonary, Allergy/Immunology, Cystic Fibrosis and Sleep, Department of Pediatrics, Emory University, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823629PMC
December 2013

Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio).

Aquat Toxicol 2013 Oct 20;142-143:447-57. Epub 2013 Sep 20.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA; Departamento de Bioquímica, CCB, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil.

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http://dx.doi.org/10.1016/j.aquatox.2013.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873750PMC
October 2013

The African coelacanth genome provides insights into tetrapod evolution.

Nature 2013 Apr;496(7445):311-6

Molecular Genetics Program, Benaroya Research Institute, Seattle, Washington 98101, USA.

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http://dx.doi.org/10.1038/nature12027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633110PMC
April 2013

Differential sensitivity to pro-oxidant exposure in two populations of killifish (Fundulus heteroclitus).

Ecotoxicology 2013 Mar 18;22(2):387-401. Epub 2013 Jan 18.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1007/s10646-012-1033-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573531PMC
March 2013

Amino acid sequence of the ligand-binding domain of the aryl hydrocarbon receptor 1 predicts sensitivity of wild birds to effects of dioxin-like compounds.

Toxicol Sci 2013 Jan 24;131(1):139-52. Epub 2012 Aug 24.

Centre for Advanced Research in Environmental Genomics, Department of Biology, University of Ottawa, Ottawa, Ontario, Canada K1N 6N5.

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http://dx.doi.org/10.1093/toxsci/kfs259DOI Listing
January 2013

Effects of short-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on microRNA expression in zebrafish embryos.

Toxicol Appl Pharmacol 2012 Oct 18;264(2):262-73. Epub 2012 Aug 18.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1016/j.taap.2012.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471217PMC
October 2012

Sequence and in vitro function of chicken, ring-necked pheasant, and Japanese quail AHR1 predict in vivo sensitivity to dioxins.

Environ Sci Technol 2012 Mar 16;46(5):2967-75. Epub 2012 Feb 16.

Centre for Advanced Research in Environmental Genomics, Department of Biology, University of Ottawa , Ottawa, Ontario K1N 6N5, Canada.

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http://dx.doi.org/10.1021/es2043992DOI Listing
March 2012

Nrf2b, novel zebrafish paralog of oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2).

J Biol Chem 2012 Feb 15;287(7):4609-27. Epub 2011 Dec 15.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts 02543, USA.

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http://dx.doi.org/10.1074/jbc.M111.260125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281635PMC
February 2012

Mechanistic research in aquatic toxicology: perspectives and future directions.

Authors:
Mark E Hahn

Aquat Toxicol 2011 Oct 12;105(3-4 Suppl):67-71. Epub 2011 Jun 12.

Biology Department, MS #32, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, United States.

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http://dx.doi.org/10.1016/j.aquatox.2011.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220193PMC
October 2011

Reduced cytochrome P4501A activity and recovery from oxidative stress during subchronic benzo[a]pyrene and benzo[e]pyrene treatment of rainbow trout.

Toxicol Appl Pharmacol 2011 Jul 29;254(1):1-7. Epub 2011 Apr 29.

Oregon State University, Department of Environmental and Molecular Toxicology, Corvallis, OR, USA.

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http://dx.doi.org/10.1016/j.taap.2011.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124960PMC
July 2011

Mechanistic basis of resistance to PCBs in Atlantic tomcod from the Hudson River.

Science 2011 Mar 17;331(6022):1322-5. Epub 2011 Feb 17.

Department of Environmental Medicine, New York University School of Medicine,Tuxedo, NY 10987, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1197296
Publisher Site
http://dx.doi.org/10.1126/science.1197296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246799PMC
March 2011

Role of DNA methylation of AHR1 and AHR2 promoters in differential sensitivity to PCBs in Atlantic Killifish, Fundulus heteroclitus.

Aquat Toxicol 2011 Jan 30;101(1):288-94. Epub 2010 Oct 30.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1016/j.aquatox.2010.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019765PMC
January 2011

Cytochrome P450 diversity and induction by gorgonian allelochemicals in the marine gastropod Cyphoma gibbosum.

BMC Ecol 2010 Dec 1;10:24. Epub 2010 Dec 1.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1186/1472-6785-10-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022543PMC
December 2010

The role of multixenobiotic transporters in predatory marine molluscs as counter-defense mechanisms against dietary allelochemicals.

Comp Biochem Physiol C Toxicol Pharmacol 2010 Sep 21;152(3):288-300. Epub 2010 May 21.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1016/j.cbpc.2010.05.003DOI Listing
September 2010

Generalized concentration addition predicts joint effects of aryl hydrocarbon receptor agonists with partial agonists and competitive antagonists.

Environ Health Perspect 2010 May;118(5):666-72

Environmental Health Department, Boston University School of Public Health, Boston, Massachusetts 02118 , USA.

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http://dx.doi.org/10.1289/ehp.0901312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866683PMC
May 2010

Biochemical warfare on the reef: the role of glutathione transferases in consumer tolerance of dietary prostaglandins.

PLoS One 2010 Jan 6;5(1):e8537. Epub 2010 Jan 6.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008537PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796389PMC
January 2010

The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish.

Chem Biol Interact 2009 Oct 15;181(3):447-54. Epub 2009 Jul 15.

Biology Dept., Redfield 3-42, MS #32 Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1016/j.cbi.2009.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838191PMC
October 2009

Interaction of fish aryl hydrocarbon receptor paralogs (AHR1 and AHR2) with the retinoblastoma protein.

Aquat Toxicol 2009 Aug 2;94(1):47-55. Epub 2009 Jun 2.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1016/j.aquatox.2009.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833323PMC
August 2009

Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor.

Biochem Pharmacol 2009 Feb 20;77(4):485-97. Epub 2008 Sep 20.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000629520800640
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http://dx.doi.org/10.1016/j.bcp.2008.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701375PMC
February 2009

Proteomic identification, cDNA cloning and enzymatic activity of glutathione S-transferases from the generalist marine gastropod, Cyphoma gibbosum.

Arch Biochem Biophys 2008 Oct 17;478(1):7-17. Epub 2008 Jul 17.

Biology Department, Woods Hole Oceanographic Institution, MS 32, 45 Water Street, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1016/j.abb.2008.07.007DOI Listing
October 2008

Key amino acids in the aryl hydrocarbon receptor predict dioxin sensitivity in avian species.

Environ Sci Technol 2008 Oct;42(19):7535-41

Department of Biology, Centre for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1021/es801082aDOI Listing
October 2008

Development of the morpholino gene knockdown technique in Fundulus heteroclitus: a tool for studying molecular mechanisms in an established environmental model.

Aquat Toxicol 2008 May 23;87(4):289-95. Epub 2008 Feb 23.

Nicholas School of the Environment and Earth Sciences, Duke University, Durham, NC 27708-0328, United States.

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http://dx.doi.org/10.1016/j.aquatox.2008.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413436PMC
May 2008

Fish models in toxicology.

Zebrafish 2007 ;4(1):9-20

Great Lakes Wisconsin Aquaculture Technology and Environmental Research (WATER) Institute, University of Wisconsin-Milwaukee, 600 E. Greenfield Avenue, Milwaukee, WI 53204, USA.

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http://dx.doi.org/10.1089/zeb.2006.9998DOI Listing
March 2008

Volumetric neuroimaging of the atlantic white-sided dolphin (Lagenorhynchus acutus) brain from in situ magnetic resonance images.

Anat Rec (Hoboken) 2008 Mar;291(3):263-82

Department of Biology, Woods Hole Oceanographic Institution, Woods Hole, MA, USA.

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http://dx.doi.org/10.1002/ar.20654DOI Listing
March 2008

Functional properties of the four Atlantic salmon (Salmo salar) aryl hydrocarbon receptor type 2 (AHR2) isoforms.

Aquat Toxicol 2008 Jan 1;86(2):121-30. Epub 2007 Nov 1.

Woods Hole Oceanographic Institution, Biology Department, Woods Hole, MA, USA.

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http://dx.doi.org/10.1016/j.aquatox.2007.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2264924PMC
January 2008

Neuroanatomy of the subadult and fetal brain of the Atlantic white-sided dolphin (Lagenorhynchus acutus) from in situ magnetic resonance images.

Anat Rec (Hoboken) 2007 Dec;290(12):1459-79

Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, USA.

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http://dx.doi.org/10.1002/ar.20612DOI Listing
December 2007

Functional characterization and evolutionary history of two aryl hydrocarbon receptor isoforms (AhR1 and AhR2) from avian species.

Toxicol Sci 2007 Sep 7;99(1):101-17. Epub 2007 Jun 7.

Center for Marine Environmental Studies (CMES), Ehime University, Matsuyama 790-8577, Japan.

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http://dx.doi.org/10.1093/toxsci/kfm139DOI Listing
September 2007

The genome of the sea urchin Strongylocentrotus purpuratus.

Authors:
Erica Sodergren George M Weinstock Eric H Davidson R Andrew Cameron Richard A Gibbs Robert C Angerer Lynne M Angerer Maria Ina Arnone David R Burgess Robert D Burke James A Coffman Michael Dean Maurice R Elphick Charles A Ettensohn Kathy R Foltz Amro Hamdoun Richard O Hynes William H Klein William Marzluff David R McClay Robert L Morris Arcady Mushegian Jonathan P Rast L Courtney Smith Michael C Thorndyke Victor D Vacquier Gary M Wessel Greg Wray Lan Zhang Christine G Elsik Olga Ermolaeva Wratko Hlavina Gretchen Hofmann Paul Kitts Melissa J Landrum Aaron J Mackey Donna Maglott Georgia Panopoulou Albert J Poustka Kim Pruitt Victor Sapojnikov Xingzhi Song Alexandre Souvorov Victor Solovyev Zheng Wei Charles A Whittaker Kim Worley K James Durbin Yufeng Shen Olivier Fedrigo David Garfield Ralph Haygood Alexander Primus Rahul Satija Tonya Severson Manuel L Gonzalez-Garay Andrew R Jackson Aleksandar Milosavljevic Mark Tong Christopher E Killian Brian T Livingston Fred H Wilt Nikki Adams Robert Bellé Seth Carbonneau Rocky Cheung Patrick Cormier Bertrand Cosson Jenifer Croce Antonio Fernandez-Guerra Anne-Marie Genevière Manisha Goel Hemant Kelkar Julia Morales Odile Mulner-Lorillon Anthony J Robertson Jared V Goldstone Bryan Cole David Epel Bert Gold Mark E Hahn Meredith Howard-Ashby Mark Scally John J Stegeman Erin L Allgood Jonah Cool Kyle M Judkins Shawn S McCafferty Ashlan M Musante Robert A Obar Amanda P Rawson Blair J Rossetti Ian R Gibbons Matthew P Hoffman Andrew Leone Sorin Istrail Stefan C Materna Manoj P Samanta Viktor Stolc Waraporn Tongprasit Qiang Tu Karl-Frederik Bergeron Bruce P Brandhorst James Whittle Kevin Berney David J Bottjer Cristina Calestani Kevin Peterson Elly Chow Qiu Autumn Yuan Eran Elhaik Dan Graur Justin T Reese Ian Bosdet Shin Heesun Marco A Marra Jacqueline Schein Michele K Anderson Virginia Brockton Katherine M Buckley Avis H Cohen Sebastian D Fugmann Taku Hibino Mariano Loza-Coll Audrey J Majeske Cynthia Messier Sham V Nair Zeev Pancer David P Terwilliger Cavit Agca Enrique Arboleda Nansheng Chen Allison M Churcher F Hallböök Glen W Humphrey Mohammed M Idris Takae Kiyama Shuguang Liang Dan Mellott Xiuqian Mu Greg Murray Robert P Olinski Florian Raible Matthew Rowe John S Taylor Kristin Tessmar-Raible D Wang Karen H Wilson Shunsuke Yaguchi Terry Gaasterland Blanca E Galindo Herath J Gunaratne Celina Juliano Masashi Kinukawa Gary W Moy Anna T Neill Mamoru Nomura Michael Raisch Anna Reade Michelle M Roux Jia L Song Yi-Hsien Su Ian K Townley Ekaterina Voronina Julian L Wong Gabriele Amore Margherita Branno Euan R Brown Vincenzo Cavalieri Véronique Duboc Louise Duloquin Constantin Flytzanis Christian Gache François Lapraz Thierry Lepage Annamaria Locascio Pedro Martinez Giorgio Matassi Valeria Matranga Ryan Range Francesca Rizzo Eric Röttinger Wendy Beane Cynthia Bradham Christine Byrum Tom Glenn Sofia Hussain Gerard Manning Esther Miranda Rebecca Thomason Katherine Walton Athula Wikramanayke Shu-Yu Wu Ronghui Xu C Titus Brown Lili Chen Rachel F Gray Pei Yun Lee Jongmin Nam Paola Oliveri Joel Smith Donna Muzny Stephanie Bell Joseph Chacko Andrew Cree Stacey Curry Clay Davis Huyen Dinh Shannon Dugan-Rocha Jerry Fowler Rachel Gill Cerrissa Hamilton Judith Hernandez Sandra Hines Jennifer Hume Laronda Jackson Angela Jolivet Christie Kovar Sandra Lee Lora Lewis George Miner Margaret Morgan Lynne V Nazareth Geoffrey Okwuonu David Parker Ling-Ling Pu Rachel Thorn Rita Wright

Science 2006 Nov;314(5801):941-52

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http://dx.doi.org/10.1126/science.1133609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159423PMC
November 2006

Unexpected diversity of aryl hydrocarbon receptors in non-mammalian vertebrates: insights from comparative genomics.

J Exp Zool A Comp Exp Biol 2006 Sep;305(9):693-706

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, USA.

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http://dx.doi.org/10.1002/jez.a.323DOI Listing
September 2006

Development and characterization of polyclonal antibodies against the aryl hydrocarbon receptor protein family (AHR1, AHR2, and AHR repressor) of Atlantic killifish Fundulus heteroclitus.

Comp Biochem Physiol C Toxicol Pharmacol 2006 Jan-Feb;142(1-2):85-94. Epub 2005 Dec 20.

Biology Department, Woods Hole Oceanographic Institution, MA 02543, USA.

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http://dx.doi.org/10.1016/j.cbpc.2005.10.013DOI Listing
April 2006

The molecular basis for differential dioxin sensitivity in birds: role of the aryl hydrocarbon receptor.

Proc Natl Acad Sci U S A 2006 Apr 10;103(16):6252-7. Epub 2006 Apr 10.

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1073/pnas.0509950103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435364PMC
April 2006

AHR1B, a new functional aryl hydrocarbon receptor in zebrafish: tandem arrangement of ahr1b and ahr2 genes.

Biochem J 2005 Nov;392(Pt 1):153-61

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1042/BJ20050713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1317674PMC
November 2005

The aryl hydrocarbon receptor constitutively represses c-myc transcription in human mammary tumor cells.

Oncogene 2005 Nov;24(53):7869-81

Department of Environmental Health, Boston University School of Public Health, Boston, MA 02118, USA.

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http://dx.doi.org/10.1038/sj.onc.1208938DOI Listing
November 2005

Duplicate aryl hydrocarbon receptor repressor genes (ahrr1 and ahrr2) in the zebrafish Danio rerio: structure, function, evolution, and AHR-dependent regulation in vivo.

Arch Biochem Biophys 2005 Sep;441(2):151-67

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1016/j.abb.2005.07.008DOI Listing
September 2005

Two zebrafish alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V alcohol dehydrogenase genes but have distinct functional characteristics.

J Biol Chem 2004 Sep 1;279(37):38303-12. Epub 2004 Jul 1.

Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon 97331, USA.

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http://dx.doi.org/10.1074/jbc.M401165200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261772PMC
September 2004

Aryl hydrocarbon receptor polymorphisms and dioxin resistance in Atlantic killifish (Fundulus heteroclitus).

Pharmacogenetics 2004 Feb;14(2):131-43

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts 02543-1049, USA.

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http://www.whoi.edu/science/B/people/mhahn/Hahn_Pharmacogene
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February 2004

Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories.

Environ Toxicol Chem 2003 Oct;22(10):2337-43

Nicholas School of the Environment and Earth Sciences and Integrated Toxicology Program, Duke University, Durham, North Carolina 27708-0328, USA.

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http://dx.doi.org/10.1897/02-495DOI Listing
October 2003

Naturally produced halogenated dimethyl bipyrroles bind to the aryl hydrocarbon receptor and induce cytochrome P4501A and porphyrin accumulation in chicken embryo hepatocytes.

Environ Toxicol Chem 2003 Jul;22(7):1622-31

Centre for Analytical and Environmental Chemistry, Carleton University, Ottawa, Ontario K1S 5B6, Canada.

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July 2003

Gonadal feminization and halogenated environmental contaminants in common terns (Sterna hirundo): evidence that ovotestes in male embryos do not persist to the prefledgling stage.

Ecotoxicology 2003 Feb-Aug;12(1-4):125-40

Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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June 2003

cDNA cloning of an aryl hydrocarbon receptor from Baikal seals (Phoca sibirica).

Mar Environ Res 2002 Sep-Dec;54(3-5):285-9

Environmental Chemistry and Ecotoxicology, Center for Marine Environmental Studies, Ehime University, Matsuyama, Japan.

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November 2002

A ligand for the aryl hydrocarbon receptor isolated from lung.

Proc Natl Acad Sci U S A 2002 Nov 30;99(23):14694-9. Epub 2002 Oct 30.

Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin, Madison 53706, USA.

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http://dx.doi.org/10.1073/pnas.232562899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137481PMC
November 2002

Expression of P-glycoprotein in killifish (Fundulus heteroclitus) exposed to environmental xenobiotics.

Aquat Toxicol 2002 Sep;59(3-4):237-51

Department of Biology, Mail Stop #32, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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September 2002

Aryl hydrocarbon receptors: diversity and evolution.

Authors:
Mark E Hahn

Chem Biol Interact 2002 Sep;141(1-2):131-60

Biology Department, Woods Hole Oceanographic Institution, Redfield 340, MS 32, 45 Water Street, MA 02543-1049, USA.

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http://dx.doi.org/10.1016/s0009-2797(02)00070-4DOI Listing
September 2002

Binding of polycyclic aromatic hydrocarbons (PAHs) to teleost aryl hydrocarbon receptors (AHRs).

Comp Biochem Physiol B Biochem Mol Biol 2002 Sep;133(1):55-68

Department of Biology, Queen's University, ON, Kingston, Canada.

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http://dx.doi.org/10.1016/s1096-4959(02)00105-7DOI Listing
September 2002

Relationships among the cell cycle, cell proliferation, and aryl hydrocarbon receptor expression in PLHC-1 cells.

Aquat Toxicol 2002 Aug;58(3-4):201-13

Biology Department, Redfield 340, MS 32, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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August 2002

The zebrafish (Danio rerio) aryl hydrocarbon receptor type 1 is a novel vertebrate receptor.

Mol Pharmacol 2002 Aug;62(2):234-49

Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1124/mol.62.2.234DOI Listing
August 2002

cDNA cloning and characterization of an aryl hydrocarbon receptor from the harbor seal (Phoca vitulina): a biomarker of dioxin susceptibility?

Aquat Toxicol 2002 Jul;58(1-2):57-73

Biology Department, MS 32, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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July 2002

Serum withdrawal leads to reduced aryl hydrocarbon receptor expression and loss of cytochrome P4501A inducibility in PLHC-1 cells.

Biochem Pharmacol 2002 Apr;63(8):1405-14

Biology Department, Redfield 340, MS 32, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.

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http://dx.doi.org/10.1016/s0006-2952(02)00892-4DOI Listing
April 2002

Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment.

Authors:
Mark E Hahn

Sci Total Environ 2002 Apr;289(1-3):49-69

Biology Department, Woods Hole Oceanographic Institution, MA 02543-1049, USA.

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http://dx.doi.org/10.1016/s0048-9697(01)01016-6DOI Listing
April 2002