Mark Dickson

The Louis V. Gerstner Graduate School of Biomedical Sciences, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, 10065, USA.

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August 2017

A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours.

Authors:

Maja de Jonge Vincent A de Weger Mark A Dickson Marlies Langenberg Axel Le Cesne Andrew J Wagner Karl Hsu Wei Zheng Sandrine Macé Gilles Tuffal Koruth Thomas Jan H M Schellens

Eur J Cancer 2017 05 17;76:144-151. Epub 2017 Mar 17.

The Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address:

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May 2017

Combined KIT and CTLA-4 Blockade in Patients with Refractory GIST and Other Advanced Sarcomas: A Phase Ib Study of Dasatinib plus Ipilimumab.

Clin Cancer Res 2017 Jun 22;23(12):2972-2980. Epub 2016 Dec 22.

Department of Medicine, Sarcoma Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.

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June 2017

Dermatofibrosarcoma Protuberans-Like Tumor With COL1A1 Copy Number Gain in the Absence of t(17;22).

Authors:

Jad Saab Ian M Rosenthal Lu Wang Klaus J Busam Kishwer S Nehal Mark A Dickson Meera R Hameed Travis J Hollmann

Am J Dermatopathol 2017 Apr;39(4):304-309

*Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY; †Department of Medicine, Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY; and ‡Department of Medicine, Memorial Sloan Kettering Cancer Center and Department of Medicine, Weill Cornell Medical College, New York, NY.

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April 2017

Relationship between physician-adjudicated adverse events and patient-reported health-related quality of life in a phase II clinical trial (NCT01143402) of patients with metastatic uveal melanoma.

J Cancer Res Clin Oncol 2017 Mar 5;143(3):439-445. Epub 2016 Dec 5.

Columbia University Medical Center, New York, NY, USA.

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March 2017

Liposarcoma: Multimodality Management and Future Targeted Therapies.

Authors:

Aimee M Crago Mark A Dickson

Surg Oncol Clin N Am 2016 10 30;25(4):761-73. Epub 2016 Jul 30.

Sarcoma Disease Management Team, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; Sarcoma Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY 10065, USA; Department of Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.

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October 2016

TP53 mutations emerge with HDM2 inhibitor SAR405838 treatment in de-differentiated liposarcoma.

Authors:

Joonil Jung Joon Sang Lee Mark A Dickson Gary K Schwartz Axel Le Cesne Andrea Varga Rastilav Bahleda Andrew J Wagner Edwin Choy Maja J de Jonge Madelyn Light Steve Rowley Sandrine Macé James Watters

Nat Commun 2016 08 31;7:12609. Epub 2016 Aug 31.

Sanofi Oncology, Cambridge, Massachusetts 02139, USA.

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August 2016

Phase IB Study of Selinexor, a First-in-Class Inhibitor of Nuclear Export, in Patients With Advanced Refractory Bone or Soft Tissue Sarcoma.

J Clin Oncol 2016 09 25;34(26):3166-74. Epub 2016 Jul 25.

Mrinal M. Gounder, William D. Tap, Mark A. Dickson, Mary Louise Keohan, Sandra P. D'Angelo, Mercedes Condy, Lanier Tanner, Joseph P. Erinjeri, and Francis H. Jasmine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College; Gary K. Schwartz, Columbia University Medical Center, New York, NY; Alona Zer, Samer Salah, Abha A. Gupta, Herbert H. Loong, Stephanie Baker, Kjirsten Nyquist-Schultz, and Albiruni Ryan Abdul Razak, Princess Margaret Cancer Center, Toronto, Ontario, Canada; and Sharon Friedlander, Robert Carlson, Thaddeus J. Unger, Jean-Richard Saint-Martin, Tami Rashal, Joel Ellis, Michael Kauffman, and Sharon Shacham, Karyopharm Therapeutics, Newton, MA.

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September 2016

Progression-Free Survival Among Patients With Well-Differentiated or Dedifferentiated Liposarcoma Treated With CDK4 Inhibitor Palbociclib: A Phase 2 Clinical Trial.

Authors:

Mark A Dickson Gary K Schwartz Mary Louise Keohan Sandra P D'Angelo Mrinal M Gounder Ping Chi Cristina R Antonescu Jonathan Landa Li-Xuan Qin Aimee M Crago Samuel Singer Andrew Koff William D Tap

JAMA Oncol 2016 Jul;2(7):937-40

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York8Weill Cornell Medical College, New York, New York.

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July 2016

Autoimmune Bullous Skin Disorders with Immune Checkpoint Inhibitors Targeting PD-1 and PD-L1.

Authors:

Jarushka Naidoo Katja Schindler Christiane Querfeld Klaus Busam Jane Cunningham David B Page Michael A Postow Alyona Weinstein Anna Skripnik Lucas Kathryn T Ciccolini Elizabeth A Quigley Alexander M Lesokhin Paul K Paik Jamie E Chaft Neil H Segal Sandra P D'Angelo Mark A Dickson Jedd D Wolchok Mario E Lacouture

Cancer Immunol Res 2016 05 29;4(5):383-9. Epub 2016 Feb 29.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Weill Cornell Medical College, New York, New York. Department of Dermatology, Memorial Sloan Kettering Cancer Center, New York, New York.

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May 2016

Preclinical and first-in-human phase I studies of KW-2450, an oral tyrosine kinase inhibitor with insulin-like growth factor receptor-1/insulin receptor selectivity.

Authors:

Gary K Schwartz Mark A Dickson Patricia M LoRusso Edward A Sausville Yoshimi Maekawa Yasuo Watanabe Naomi Kashima Daisuke Nakashima Shiro Akinaga

Cancer Sci 2016 Apr 28;107(4):499-506. Epub 2016 Mar 28.

Tokyo Research Park, R&D Division, Kyowa Hakko Kirin Co., Ltd., Tokyo, Japan.

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April 2016

Reply to A. Indini et al.

Authors:

Troy Z Horvat Nelly G Adel Thu-Oanh Dang Parisa Momtaz Michael A Postow Margaret K Callahan Richard D Carvajal Mark A Dickson Sandra P D'Angelo Kaitlin M Woo Katherine S Panageas Jedd D Wolchok Paul B Chapman

J Clin Oncol 2016 Mar 19;34(9):1018-9. Epub 2016 Jan 19.

Memorial Sloan Kettering Cancer Center; and Weill Cornell Medical College, New York, NY

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March 2016

Kaposi Sarcoma of Childhood: Inborn or Acquired Immunodeficiency to Oncogenic HHV-8.

Authors:

Carolyn C Jackson Mark A Dickson Mahan Sadjadi Antoine Gessain Laurent Abel Emmanuelle Jouanguy Jean-Laurent Casanova

Pediatr Blood Cancer 2016 Mar 15;63(3):392-7. Epub 2015 Oct 15.

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York.

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March 2016

A Phase Ib/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib for the Neoadjuvant Treatment of Soft Tissue Sarcomas.

Oncologist 2015 Nov 8;20(11):1245-6. Epub 2015 Oct 8.

Memorial Sloan Kettering Cancer Center, New York, New York, USA Weill Cornell Medical College, New York, New York, USA

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November 2015

Impact of surgery, radiation and systemic therapy on the outcomes of patients with dendritic cell and histiocytic sarcomas.

Authors:

Mrinal Gounder Ved Desai Deborah Kuk Narasimhan Agaram Maria Arcila Benjamin Durham Mary L Keohan Mark A Dickson Sandra P D'Angelo Neerav Shukla Craig Moskowitz Ariela Noy Robert G Maki Diego Adrianzen Herrera Armando Sanchez Anita Krishnan Andrew Pourmoussa Li-Xuan Qin William D Tap

Eur J Cancer 2015 Nov 19;51(16):2413-22. Epub 2015 Aug 19.

Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY 10065, USA.

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November 2015

Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center.

Authors:

Troy Z Horvat Nelly G Adel Thu-Oanh Dang Parisa Momtaz Michael A Postow Margaret K Callahan Richard D Carvajal Mark A Dickson Sandra P D'Angelo Kaitlin M Woo Katherine S Panageas Jedd D Wolchok Paul B Chapman

J Clin Oncol 2015 Oct 17;33(28):3193-8. Epub 2015 Aug 17.

Troy Z. Horvat, Nelly G. Adel, Thu-Oanh Dang, Kaitlin M. Woo, Katherine S. Panageas, Parisa Momtaz, Michael A. Postow, Margaret K. Callahan, Richard D. Carvajal, Mark A. Dickson, Sandra P. D'Angelo, Jedd D. Wolchok, and Paul B. Chapman, Memorial Sloan Kettering Cancer Center; Jedd D. Wolchok, Ludwig Institute for Cancer Research; and Michael A. Postow, Margaret K. Callahan, Richard D. Carvajal, Mark A. Dickson, Sandra P. D'Angelo, Jedd D. Wolchok, and Paul B. Chapman, Weill Cornell Medical College, New York, NY.

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October 2015

Phase II Trial of Gemcitabine and Docetaxel with Bevacizumab in Soft Tissue Sarcoma.

Authors:

Mark A Dickson David R D'Adamo Mary L Keohan Sandra P D'Angelo Richard D Carvajal Mrinal M Gounder Robert G Maki Li-Xuan Qin Robert A Lefkowitz Olivia R McKennon Catherine M Hirst Gary K Schwartz William D Tap

Sarcoma 2015 14;2015:532478. Epub 2015 May 14.

Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA.

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June 2015

Outcomes of Systemic Therapy for Patients with Metastatic Angiosarcoma.

Authors:

Sandra P D'Angelo Rodrigo R Munhoz Deborah Kuk Johnathan Landa Eliza W Hartley Michael Bonafede Mark A Dickson Mrinal Gounder Mary L Keohan Aimee M Crago Cristina R Antonescu William D Tap

Oncology 2015 3;89(4):205-14. Epub 2015 Jun 3.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, N.Y., USA.

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December 2015

MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition.

Authors:

Marta Kovatcheva David D Liu Mark A Dickson Mary E Klein Rachael O'Connor Fatima O Wilder Nicholas D Socci William D Tap Gary K Schwartz Samuel Singer Aimee M Crago Andrew Koff

Oncotarget 2015 Apr;6(10):8226-43

The Louis V. Gerstner Graduate School of Biomedical Sciences, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, USA.

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April 2015

Dichotomy of Genetic Abnormalities in PEComas With Therapeutic Implications.

Authors:

Narasimhan P Agaram Yun-Shao Sung Lei Zhang Chun-Liang Chen Hsiao-Wei Chen Samuel Singer Mark A Dickson Michael F Berger Cristina R Antonescu

Am J Surg Pathol 2015 Jun;39(6):813-25

Departments of *Pathology †Surgery §Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center ‡Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY.

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June 2015

InformedTogether: Usability Evaluation of a Web-Based Decision Aid to Facilitate Shared Advance Care Planning for Severe Chronic Obstructive Pulmonary Disease.

Authors:

Lauren M Uhler Rafael E Pérez Figueroa Mark Dickson Lauren McCullagh Andre Kushniruk Helen Monkman Holly O Witteman Negin Hajizadeh

JMIR Hum Factors 2015 Feb 25;2(1):e2. Epub 2015 Feb 25.

Department of Medicine, Hofstra North Shore LIJ School of Medicine, North Shore LIJ Health System, Manhasset, NY, United States.

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February 2015

Prevalence of tumor-infiltrating lymphocytes and PD-L1 expression in the soft tissue sarcoma microenvironment.

Authors:

Sandra P D'Angelo Alexander N Shoushtari Narasimhan P Agaram Deborah Kuk Li-Xuan Qin Richard D Carvajal Mark A Dickson Mrinal Gounder Mary Louise Keohan Gary K Schwartz William D Tap

Hum Pathol 2015 Mar 15;46(3):357-65. Epub 2014 Nov 15.

Sarcoma Service, Dept. of Medicine, Memorial Sloan Kettering Cancer Center, 10065 New York, New York; Weill Cornell Medical College, 10065 New York, New York.

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March 2015

Phase I study of XL281 (BMS-908662), a potent oral RAF kinase inhibitor, in patients with advanced solid tumors.

Authors:

Mark A Dickson Michael S Gordon Gerald Edelman Johanna C Bendell Ragini R Kudchadkar Patricia M LoRusso Stuart H Johnston Douglas O Clary Gary K Schwartz

Invest New Drugs 2015 Apr 5;33(2):349-56. Epub 2014 Dec 5.

Memorial Sloan Kettering Cancer Center, New York, NY, USA,

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April 2015

Systemic treatment options for radiation-associated sarcomas.

Authors:

Mark A Dickson

Curr Treat Options Oncol 2014 Sep;15(3):476-81

Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, 300 E 66th St, New York, NY, 10065, USA,

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September 2014

Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial.

JAMA 2014 Jun;311(23):2397-405

Memorial Sloan-Kettering Cancer Center, New York, New York2Weill Medical College of Cornell University, New York, New York.

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June 2014

Acute myeloid leukemia arising from a donor derived premalignant hematopoietic clone: A possible mechanism for the origin of leukemia in donor cells.

Authors:

Mark A Dickson Esperanza B Papadopoulos Cyrus V Hedvat Suresh C Jhanwar Renier J Brentjens

Leuk Res Rep 2014 20;3(2):38-41. Epub 2014 May 20.

Departments of Medicine (M.A.D., E.B.P., S.C.J., R.J.B.) and Pathology (S.C.J., C.V.H.), Memorial Sloan-Kettering Cancer Center, New York, N.Y. 10065, USA.

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June 2014

Molecular pathways: CDK4 inhibitors for cancer therapy.

Authors:

Mark A Dickson

Clin Cancer Res 2014 Jul 2;20(13):3379-83. Epub 2014 May 2.

Author's Affiliation: Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York

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July 2014

Myasthenia Gravis Induced by Ipilimumab in Patients With Metastatic Melanoma.

Authors:

Douglas B Johnson Vita Saranga-Perry Patrick J M Lavin W Bryan Burnette Stephen W Clark David R Uskavitch Deborah E Wallace Mark A Dickson Ragini R Kudchadkar Jeffrey A Sosman

J Clin Oncol 2015 Nov 28;33(33):e122-4. Epub 2014 Apr 28.

Vanderbilt University Medical Center, Nashville, TN.

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November 2015

Animated randomness, avatars, movement, and personalization in risk graphics.

Authors:

Holly O Witteman Andrea Fuhrel-Forbis Harindra C Wijeysundera Nicole Exe Mark Dickson Lisa Holtzman Valerie C Kahn Brian J Zikmund-Fisher

J Med Internet Res 2014 Mar 18;16(3):e80. Epub 2014 Mar 18.

Department of Family and Emergency Medicine, Faculty of Medicine, Laval University, Quebec City, QC, Canada.

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March 2014

Blocks, ovals, or people? Icon type affects risk perceptions and recall of pictographs.

Authors:

Brian J Zikmund-Fisher Holly O Witteman Mark Dickson Andrea Fuhrel-Forbis Valerie C Kahn Nicole L Exe Melissa Valerio Lisa G Holtzman Laura D Scherer Angela Fagerlin

Med Decis Making 2014 05 18;34(4):443-53. Epub 2013 Nov 18.

Division of General Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI (BJZF, AF)

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May 2014

Clinical activity of ipilimumab for metastatic uveal melanoma: a retrospective review of the Dana-Farber Cancer Institute, Massachusetts General Hospital, Memorial Sloan-Kettering Cancer Center, and University Hospital of Lausanne experience.

Cancer 2013 Oct 2;119(20):3687-95. Epub 2013 Aug 2.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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October 2013

Ipilimumab for patients with advanced mucosal melanoma.

Oncologist 2013 Jun 28;18(6):726-32. Epub 2013 May 28.

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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June 2013

Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma.

Authors:

Mark A Dickson William D Tap Mary Louise Keohan Sandra P D'Angelo Mrinal M Gounder Cristina R Antonescu Jonathan Landa Li-Xuan Qin Dustin D Rathbone Mercedes M Condy Yelena Ustoyev Aimee M Crago Samuel Singer Gary K Schwartz

J Clin Oncol 2013 Jun 8;31(16):2024-8. Epub 2013 Apr 8.

Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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June 2013

Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial.

Lancet Oncol 2013 Apr 8;14(4):371-82. Epub 2013 Mar 8.

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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April 2013

Theria-specific homeodomain and cis-regulatory element evolution of the Dlx3-4 bigene cluster in 12 different mammalian species.

Authors:

Kenta Sumiyama Tsutomu Miyake Jane Grimwood Andrew Stuart Mark Dickson Jeremy Schmutz Frank H Ruddle Richard M Myers Chris T Amemiya

J Exp Zool B Mol Dev Evol 2012 Dec 5;318(8):639-50. Epub 2012 Sep 5.

Division of Population Genetics, National Institute of Genetics, Mishima, Japan.

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December 2012

Extrarenal perivascular epithelioid cell tumors (PEComas) respond to mTOR inhibition: clinical and molecular correlates.

Authors:

Mark A Dickson Gary K Schwartz Cristina R Antonescu David J Kwiatkowski Izabela A Malinowska

Int J Cancer 2013 Apr 21;132(7):1711-7. Epub 2012 Sep 21.

Melanoma and Sarcoma Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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April 2013

Animated graphics for comparing two risks: a cautionary tale.

Authors:

Brian J Zikmund-Fisher Holly O Witteman Andrea Fuhrel-Forbis Nicole L Exe Valerie C Kahn Mark Dickson

J Med Internet Res 2012 Jul 25;14(4):e106. Epub 2012 Jul 25.

Department of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, MI, United States.

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July 2012

Identification of factors contributing to variability in a blood-based gene expression test.

Authors:

Michael R Elashoff Rachel Nuttall Philip Beineke Michael H Doctolero Mark Dickson Andrea M Johnson Susan E Daniels Steven Rosenberg James A Wingrove

PLoS One 2012 3;7(7):e40068. Epub 2012 Jul 3.

CardioDx, Inc., Palo Alto, California, United States of America.

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December 2012

The genomic basis of adaptive evolution in threespine sticklebacks.

Nature 2012 Apr 4;484(7392):55-61. Epub 2012 Apr 4.

Department of Developmental Biology, Beckman Center B300, Stanford University School of Medicine, Stanford California 94305, USA.

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April 2012

The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: preclinical investigations and results of a phase I dose-escalation clinical trial.

Authors:

Jason J Luke David R D'Adamo Mark A Dickson Mary Louise Keohan Richard D Carvajal Robert G Maki Elisa de Stanchina Elgilda Musi Samuel Singer Gary K Schwartz

Clin Cancer Res 2012 May 28;18(9):2638-47. Epub 2012 Feb 28.

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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May 2012

Cool but counterproductive: interactive, Web-based risk communications can backfire.

Authors:

Brian J Zikmund-Fisher Mark Dickson Holly O Witteman

J Med Internet Res 2011 Aug 25;13(3):e60. Epub 2011 Aug 25.

Department of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, MI, United States. bzikmund [at] umich.edu

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August 2011

A phase I clinical trial of safingol in combination with cisplatin in advanced solid tumors.

Authors:

Mark A Dickson Richard D Carvajal Alfred H Merrill Mithat Gonen Lauren M Cane Gary K Schwartz

Clin Cancer Res 2011 Apr 21;17(8):2484-92. Epub 2011 Jan 21.

Melanoma and Sarcoma Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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April 2011

A phase I clinical trial of FOLFIRI in combination with the pan-cyclin-dependent kinase (CDK) inhibitor flavopiridol.

Authors:

Mark A Dickson Manish A Shah Dana Rathkopf Archie Tse Richard D Carvajal Nian Wu Robert A Lefkowitz Mithat Gonen Lauren M Cane Heather J Dials Gary K Schwartz

Cancer Chemother Pharmacol 2010 Nov 21;66(6):1113-21. Epub 2010 Feb 21.

Melanoma and Sarcoma Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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November 2010

A phase I pharmacokinetic study of pulse-dose vorinostat with flavopiridol in solid tumors.

Authors:

Mark Andrew Dickson Dana E Rathkopf Richard D Carvajal Steven Grant John D Roberts Joel M Reid Matthew M Ames Renee M McGovern Robert A Lefkowitz Mithat Gonen Lauren M Cane Heather J Dials Gary K Schwartz

Invest New Drugs 2011 Oct 12;29(5):1004-12. Epub 2010 May 12.

Melanoma and Sarcoma Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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October 2011

Complete HOX cluster characterization of the coelacanth provides further evidence for slow evolution of its genome.

Authors:

Chris T Amemiya Thomas P Powers Sonja J Prohaska Jane Grimwood Jeremy Schmutz Mark Dickson Tsutomu Miyake Michael A Schoenborn Richard M Myers Francis H Ruddle Peter F Stadler

Proc Natl Acad Sci U S A 2010 Feb 5;107(8):3622-7. Epub 2010 Feb 5.

Benaroya Research Institute, Virginia Mason, Seattle, WA 98101, USA.

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February 2010

Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes.

Authors:

David L Goode Gregory M Cooper Jeremy Schmutz Mark Dickson Eidelyn Gonzales Ming Tsai Kalpana Karra Eugene Davydov Serafim Batzoglou Richard M Myers Arend Sidow

Genome Res 2010 Mar 12;20(3):301-10. Epub 2010 Jan 12.

Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.

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March 2010

Phase I study of flavopiridol with oxaliplatin and fluorouracil/leucovorin in advanced solid tumors.

Authors:

Dana Rathkopf Mark A Dickson Darren R Feldman Richard D Carvajal Manish A Shah Nian Wu Robert Lefkowitz Mithat Gonen Lauren M Cane Heather J Dials Jennifer L Winkelmann George J Bosl Gary K Schwartz

Clin Cancer Res 2009 Dec 24;15(23):7405-11. Epub 2009 Nov 24.

Genitourinary Oncology Service, Department of Medicine, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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December 2009

The completion of the Mammalian Gene Collection (MGC).

Authors:

Gary Temple Daniela S Gerhard Rebekah Rasooly Elise A Feingold Peter J Good Cristen Robinson Allison Mandich Jeffrey G Derge Jeanne Lewis Debonny Shoaf Francis S Collins Wonhee Jang Lukas Wagner Carolyn M Shenmen Leonie Misquitta Carl F Schaefer Kenneth H Buetow Tom I Bonner Linda Yankie Ming Ward Lon Phan Alex Astashyn Garth Brown Catherine Farrell Jennifer Hart Melissa Landrum Bonnie L Maidak Michael Murphy Terence Murphy Bhanu Rajput Lillian Riddick David Webb Janet Weber Wendy Wu Kim D Pruitt Donna Maglott Adam Siepel Brona Brejova Mark Diekhans Rachel Harte Robert Baertsch Jim Kent David Haussler Michael Brent Laura Langton Charles L G Comstock Michael Stevens Chaochun Wei Marijke J van Baren Kourosh Salehi-Ashtiani Ryan R Murray Lila Ghamsari Elizabeth Mello Chenwei Lin Christa Pennacchio Kirsten Schreiber Nicole Shapiro Amber Marsh Elizabeth Pardes Troy Moore Anita Lebeau Mike Muratet Blake Simmons David Kloske Stephanie Sieja James Hudson Praveen Sethupathy Michael Brownstein Narayan Bhat Joseph Lazar Howard Jacob Chris E Gruber Mark R Smith John McPherson Angela M Garcia Preethi H Gunaratne Jiaqian Wu Donna Muzny Richard A Gibbs Alice C Young Gerard G Bouffard Robert W Blakesley Jim Mullikin Eric D Green Mark C Dickson Alex C Rodriguez Jane Grimwood Jeremy Schmutz Richard M Myers Martin Hirst Thomas Zeng Kane Tse Michelle Moksa Merinda Deng Kevin Ma Diana Mah Johnson Pang Greg Taylor Eric Chuah Athena Deng Keith Fichter Anne Go Stephanie Lee Jing Wang Malachi Griffith Ryan Morin Richard A Moore Michael Mayo Sarah Munro Susan Wagner Steven J M Jones Robert A Holt Marco A Marra Sun Lu Shuwei Yang James Hartigan Marcus Graf Ralf Wagner Stanley Letovksy Jacqueline C Pulido Keith Robison Dominic Esposito James Hartley Vanessa E Wall Ralph F Hopkins Osamu Ohara Stefan Wiemann

Genome Res 2009 Dec 18;19(12):2324-33. Epub 2009 Sep 18.

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December 2009

Creating healthy work environments. The ministry today is providing more care for its caregivers.

Authors:

Mark Dickson

Health Prog 2007 Sep-Oct;88(5):18-21

Bon Secours St. Francis Hospital, Roper St. Francis Healthcare, Charleston, SC, USA.

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December 2007

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Authors:

Ewan Birney John A Stamatoyannopoulos Anindya Dutta Roderic Guigó Thomas R Gingeras Elliott H Margulies Zhiping Weng Michael Snyder Emmanouil T Dermitzakis Robert E Thurman Michael S Kuehn Christopher M Taylor Shane Neph Christoph M Koch Saurabh Asthana Ankit Malhotra Ivan Adzhubei Jason A Greenbaum Robert M Andrews Paul Flicek Patrick J Boyle Hua Cao Nigel P Carter Gayle K Clelland Sean Davis Nathan Day Pawandeep Dhami Shane C Dillon Michael O Dorschner Heike Fiegler Paul G Giresi Jeff Goldy Michael Hawrylycz Andrew Haydock Richard Humbert Keith D James Brett E Johnson Ericka M Johnson Tristan T Frum Elizabeth R Rosenzweig Neerja Karnani Kirsten Lee Gregory C Lefebvre Patrick A Navas Fidencio Neri Stephen C J Parker Peter J Sabo Richard Sandstrom Anthony Shafer David Vetrie Molly Weaver Sarah Wilcox Man Yu Francis S Collins Job Dekker Jason D Lieb Thomas D Tullius Gregory E Crawford Shamil Sunyaev William S Noble Ian Dunham France Denoeud Alexandre Reymond Philipp Kapranov Joel Rozowsky Deyou Zheng Robert Castelo Adam Frankish Jennifer Harrow Srinka Ghosh Albin Sandelin Ivo L Hofacker Robert Baertsch Damian Keefe Sujit Dike Jill Cheng Heather A Hirsch Edward A Sekinger Julien Lagarde Josep F Abril Atif Shahab Christoph Flamm Claudia Fried Jörg Hackermüller Jana Hertel Manja Lindemeyer Kristin Missal Andrea Tanzer Stefan Washietl Jan Korbel Olof Emanuelsson Jakob S Pedersen Nancy Holroyd Ruth Taylor David Swarbreck Nicholas Matthews Mark C Dickson Daryl J Thomas Matthew T Weirauch James Gilbert Jorg Drenkow Ian Bell XiaoDong Zhao K G Srinivasan Wing-Kin Sung Hong Sain Ooi Kuo Ping Chiu Sylvain Foissac Tyler Alioto Michael Brent Lior Pachter Michael L Tress Alfonso Valencia Siew Woh Choo Chiou Yu Choo Catherine Ucla Caroline Manzano Carine Wyss Evelyn Cheung Taane G Clark James B Brown Madhavan Ganesh Sandeep Patel Hari Tammana Jacqueline Chrast Charlotte N Henrichsen Chikatoshi Kai Jun Kawai Ugrappa Nagalakshmi Jiaqian Wu Zheng Lian Jin Lian Peter Newburger Xueqing Zhang Peter Bickel John S Mattick Piero Carninci Yoshihide Hayashizaki Sherman Weissman Tim Hubbard Richard M Myers Jane Rogers Peter F Stadler Todd M Lowe Chia-Lin Wei Yijun Ruan Kevin Struhl Mark Gerstein Stylianos E Antonarakis Yutao Fu Eric D Green Ulaş Karaöz Adam Siepel James Taylor Laura A Liefer Kris A Wetterstrand Peter J Good Elise A Feingold Mark S Guyer Gregory M Cooper George Asimenos Colin N Dewey Minmei Hou Sergey Nikolaev Juan I Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham Haiyan Huang Nancy R Zhang Ian Holmes James C Mullikin Abel Ureta-Vidal Benedict Paten Michael Seringhaus Deanna Church Kate Rosenbloom W James Kent Eric A Stone Serafim Batzoglou Nick Goldman Ross C Hardison David Haussler Webb Miller Arend Sidow Nathan D Trinklein Zhengdong D Zhang Leah Barrera Rhona Stuart David C King Adam Ameur Stefan Enroth Mark C Bieda Jonghwan Kim Akshay A Bhinge Nan Jiang Jun Liu Fei Yao Vinsensius B Vega Charlie W H Lee Patrick Ng Atif Shahab Annie Yang Zarmik Moqtaderi Zhou Zhu Xiaoqin Xu Sharon Squazzo Matthew J Oberley David Inman Michael A Singer Todd A Richmond Kyle J Munn Alvaro Rada-Iglesias Ola Wallerman Jan Komorowski Joanna C Fowler Phillippe Couttet Alexander W Bruce Oliver M Dovey Peter D Ellis Cordelia F Langford David A Nix Ghia Euskirchen Stephen Hartman Alexander E Urban Peter Kraus Sara Van Calcar Nate Heintzman Tae Hoon Kim Kun Wang Chunxu Qu Gary Hon Rosa Luna Christopher K Glass M Geoff Rosenfeld Shelley Force Aldred Sara J Cooper Anason Halees Jane M Lin Hennady P Shulha Xiaoling Zhang Mousheng Xu Jaafar N S Haidar Yong Yu Yijun Ruan Vishwanath R Iyer Roland D Green Claes Wadelius Peggy J Farnham Bing Ren Rachel A Harte Angie S Hinrichs Heather Trumbower Hiram Clawson Jennifer Hillman-Jackson Ann S Zweig Kayla Smith Archana Thakkapallayil Galt Barber Robert M Kuhn Donna Karolchik Lluis Armengol Christine P Bird Paul I W de Bakker Andrew D Kern Nuria Lopez-Bigas Joel D Martin Barbara E Stranger Abigail Woodroffe Eugene Davydov Antigone Dimas Eduardo Eyras Ingileif B Hallgrímsdóttir Julian Huppert Michael C Zody Gonçalo R Abecasis Xavier Estivill Gerard G Bouffard Xiaobin Guan Nancy F Hansen Jacquelyn R Idol Valerie V B Maduro Baishali Maskeri Jennifer C McDowell Morgan Park Pamela J Thomas Alice C Young Robert W Blakesley Donna M Muzny Erica Sodergren David A Wheeler Kim C Worley Huaiyang Jiang George M Weinstock Richard A Gibbs Tina Graves Robert Fulton Elaine R Mardis Richard K Wilson Michele Clamp James Cuff Sante Gnerre David B Jaffe Jean L Chang Kerstin Lindblad-Toh Eric S Lander Maxim Koriabine Mikhail Nefedov Kazutoyo Osoegawa Yuko Yoshinaga Baoli Zhu Pieter J de Jong

Nature 2007 Jun;447(7146):799-816

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June 2007

Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.

Genome Res 2007 Jun;17(6):746-59

Grup de Recerca en Informática Biomèdica, Institut Municipal d'Investigació Mèdica/Universitat Pompeu Fabra, 08003 Barcelona, Catalonia, Spain.

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June 2007

Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling.

Genome Res 2006 Jun 3;16(6):796-803. Epub 2006 May 3.

British Columbia Genome Sciences Centre, BCCA, Vancouver, BC V5Z 1L3 Canada.

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June 2006

Widespread parallel evolution in sticklebacks by repeated fixation of Ectodysplasin alleles.

Authors:

Pamela F Colosimo Kim E Hosemann Sarita Balabhadra Guadalupe Villarreal Mark Dickson Jane Grimwood Jeremy Schmutz Richard M Myers Dolph Schluter David M Kingsley

Science 2005 Mar;307(5717):1928-33

Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305-5329, USA.

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March 2005

The sequence and analysis of duplication-rich human chromosome 16.

Authors:

Joel Martin Cliff Han Laurie A Gordon Astrid Terry Shyam Prabhakar Xinwei She Gary Xie Uffe Hellsten Yee Man Chan Michael Altherr Olivier Couronne Andrea Aerts Eva Bajorek Stacey Black Heather Blumer Elbert Branscomb Nancy C Brown William J Bruno Judith M Buckingham David F Callen Connie S Campbell Mary L Campbell Evelyn W Campbell Chenier Caoile Jean F Challacombe Leslie A Chasteen Olga Chertkov Han C Chi Mari Christensen Lynn M Clark Judith D Cohn Mirian Denys John C Detter Mark Dickson Mira Dimitrijevic-Bussod Julio Escobar Joseph J Fawcett Dave Flowers Dea Fotopulos Tijana Glavina Maria Gomez Eidelyn Gonzales David Goodstein Lynne A Goodwin Deborah L Grady Igor Grigoriev Matthew Groza Nancy Hammon Trevor Hawkins Lauren Haydu Carl E Hildebrand Wayne Huang Sanjay Israni Jamie Jett Phillip B Jewett Kristen Kadner Heather Kimball Arthur Kobayashi Marie-Claude Krawczyk Tina Leyba Jonathan L Longmire Frederick Lopez Yunian Lou Steve Lowry Thom Ludeman Chitra F Manohar Graham A Mark Kimberly L McMurray Linda J Meincke Jenna Morgan Robert K Moyzis Mark O Mundt A Christine Munk Richard D Nandkeshwar Sam Pitluck Martin Pollard Paul Predki Beverly Parson-Quintana Lucia Ramirez Sam Rash James Retterer Darryl O Ricke Donna L Robinson Alex Rodriguez Asaf Salamov Elizabeth H Saunders Duncan Scott Timothy Shough Raymond L Stallings Malinda Stalvey Robert D Sutherland Roxanne Tapia Judith G Tesmer Nina Thayer Linda S Thompson Hope Tice David C Torney Mary Tran-Gyamfi Ming Tsai Levy E Ulanovsky Anna Ustaszewska Nu Vo P Scott White Albert L Williams Patricia L Wills Jung-Rung Wu Kevin Wu Joan Yang Pieter Dejong David Bruce Norman A Doggett Larry Deaven Jeremy Schmutz Jane Grimwood Paul Richardson Daniel S Rokhsar Evan E Eichler Paul Gilna Susan M Lucas Richard M Myers Edward M Rubin Len A Pennacchio

Nature 2004 Dec;432(7020):988-94

DOE Joint Genome Institute, 2800 Mitchell Avenue, Walnut Creek, California 94598, USA.

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December 2004

Coelacanth genome sequence reveals the evolutionary history of vertebrate genes.

Authors:

James P Noonan Jane Grimwood Joshua Danke Jeremy Schmutz Mark Dickson Chris T Amemiya Richard M Myers

Genome Res 2004 Dec 15;14(12):2397-405. Epub 2004 Nov 15.

Department of Genetics, Stanford University School of Medicine, Stanford, California 94305-5120, USA.

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December 2004

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Authors:

Daniela S Gerhard Lukas Wagner Elise A Feingold Carolyn M Shenmen Lynette H Grouse Greg Schuler Steven L Klein Susan Old Rebekah Rasooly Peter Good Mark Guyer Allison M Peck Jeffery G Derge David Lipman Francis S Collins Wonhee Jang Steven Sherry Mike Feolo Leonie Misquitta Eduardo Lee Kirill Rotmistrovsky Susan F Greenhut Carl F Schaefer Kenneth Buetow Tom I Bonner David Haussler Jim Kent Mark Kiekhaus Terry Furey Michael Brent Christa Prange Kirsten Schreiber Nicole Shapiro Narayan K Bhat Ralph F Hopkins Florence Hsie Tom Driscoll M Bento Soares Tom L Casavant Todd E Scheetz Michael J Brown-stein Ted B Usdin Shiraki Toshiyuki Piero Carninci Yulan Piao Dawood B Dudekula Minoru S H Ko Koichi Kawakami Yutaka Suzuki Sumio Sugano C E Gruber M R Smith Blake Simmons Troy Moore Richard Waterman Stephen L Johnson Yijun Ruan Chia Lin Wei S Mathavan Preethi H Gunaratne Jiaqian Wu Angela M Garcia Stephen W Hulyk Edwin Fuh Ye Yuan Anna Sneed Carla Kowis Anne Hodgson Donna M Muzny John McPherson Richard A Gibbs Jessica Fahey Erin Helton Mark Ketteman Anuradha Madan Stephanie Rodrigues Amy Sanchez Michelle Whiting Anup Madari Alice C Young Keith D Wetherby Steven J Granite Peggy N Kwong Charles P Brinkley Russell L Pearson Gerard G Bouffard Robert W Blakesly Eric D Green Mark C Dickson Alex C Rodriguez Jane Grimwood Jeremy Schmutz Richard M Myers Yaron S N Butterfield Malachi Griffith Obi L Griffith Martin I Krzywinski Nancy Liao Ryan Morin Ryan Morrin Diana Palmquist Anca S Petrescu Ursula Skalska Duane E Smailus Jeff M Stott Angelique Schnerch Jacqueline E Schein Steven J M Jones Robert A Holt Agnes Baross Marco A Marra Sandra Clifton Kathryn A Makowski Stephanie Bosak Joel Malek

Genome Res 2004 Oct;14(10B):2121-7

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October 2004

The DNA sequence and comparative analysis of human chromosome 5.

Authors:

Jeremy Schmutz Joel Martin Astrid Terry Olivier Couronne Jane Grimwood Steve Lowry Laurie A Gordon Duncan Scott Gary Xie Wayne Huang Uffe Hellsten Mary Tran-Gyamfi Xinwei She Shyam Prabhakar Andrea Aerts Michael Altherr Eva Bajorek Stacey Black Elbert Branscomb Chenier Caoile Jean F Challacombe Yee Man Chan Mirian Denys John C Detter Julio Escobar Dave Flowers Dea Fotopulos Tijana Glavina Maria Gomez Eidelyn Gonzales David Goodstein Igor Grigoriev Matthew Groza Nancy Hammon Trevor Hawkins Lauren Haydu Sanjay Israni Jamie Jett Kristen Kadner Heather Kimball Arthur Kobayashi Frederick Lopez Yunian Lou Diego Martinez Catherine Medina Jenna Morgan Richard Nandkeshwar James P Noonan Sam Pitluck Martin Pollard Paul Predki James Priest Lucia Ramirez James Retterer Alex Rodriguez Stephanie Rogers Asaf Salamov Angelica Salazar Nina Thayer Hope Tice Ming Tsai Anna Ustaszewska Nu Vo Jeremy Wheeler Kevin Wu Joan Yang Mark Dickson Jan-Fang Cheng Evan E Eichler Anne Olsen Len A Pennacchio Daniel S Rokhsar Paul Richardson Susan M Lucas Richard M Myers Edward M Rubin

Nature 2004 Sep;431(7006):268-74

Stanford Human Genome Center, Department of Genetics, Stanford University School of Medicine, 975 California Ave, Palo Alto, California 94304, USA.

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September 2004

The master sex-determination locus in threespine sticklebacks is on a nascent Y chromosome.

Authors:

Catherine L Peichel Joseph A Ross Clinton K Matson Mark Dickson Jane Grimwood Jeremy Schmutz Richard M Myers Seiichi Mori Dolph Schluter David M Kingsley

Curr Biol 2004 Aug;14(16):1416-24

Department of Developmental Biology and Howard Hughes Medical Institute, Stanford University School of Medicine, Palo Alto, CA 94305, USA.

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August 2004

Quality assessment of the human genome sequence.

Nature 2004 May;429(6990):365-8

Stanford Human Genome Center, Department of Genetics, Stanford University School of Medicine, 975 California Avenue, Palo Alto, California 94304, USA.

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May 2004

The DNA sequence and biology of human chromosome 19.

Authors:

Jane Grimwood Laurie A Gordon Anne Olsen Astrid Terry Jeremy Schmutz Jane Lamerdin Uffe Hellsten David Goodstein Olivier Couronne Mary Tran-Gyamfi Andrea Aerts Michael Altherr Linda Ashworth Eva Bajorek Stacey Black Elbert Branscomb Sean Caenepeel Anthony Carrano Chenier Caoile Yee Man Chan Mari Christensen Catherine A Cleland Alex Copeland Eileen Dalin Paramvir Dehal Mirian Denys John C Detter Julio Escobar Dave Flowers Dea Fotopulos Carmen Garcia Anca M Georgescu Tijana Glavina Maria Gomez Eidelyn Gonzales Matthew Groza Nancy Hammon Trevor Hawkins Lauren Haydu Isaac Ho Wayne Huang Sanjay Israni Jamie Jett Kristen Kadner Heather Kimball Arthur Kobayashi Vladimer Larionov Sun-Hee Leem Frederick Lopez Yunian Lou Steve Lowry Stephanie Malfatti Diego Martinez Paula McCready Catherine Medina Jenna Morgan Kathryn Nelson Matt Nolan Ivan Ovcharenko Sam Pitluck Martin Pollard Anthony P Popkie Paul Predki Glenda Quan Lucia Ramirez Sam Rash James Retterer Alex Rodriguez Stephanine Rogers Asaf Salamov Angelica Salazar Xinwei She Doug Smith Tom Slezak Victor Solovyev Nina Thayer Hope Tice Ming Tsai Anna Ustaszewska Nu Vo Mark Wagner Jeremy Wheeler Kevin Wu Gary Xie Joan Yang Inna Dubchak Terrence S Furey Pieter DeJong Mark Dickson David Gordon Evan E Eichler Len A Pennacchio Paul Richardson Lisa Stubbs Daniel S Rokhsar Richard M Myers Edward M Rubin Susan M Lucas

Nature 2004 Apr;428(6982):529-35

Stanford Human Genome Center, Department of Genetics, Stanford University School of Medicine, 975 California Avenue, Palo Alto, California 94304, USA.

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April 2004