Mark A Valasek

Mark A Valasek

UNVERIFIED PROFILE

Are you Mark A Valasek?   Register this Author

Register author
Mark A Valasek

Mark A Valasek

Publications by authors named "Mark A Valasek"

Are you Mark A Valasek?   Register this Author

54Publications

1758Reads

49Profile Views

Race/Ethnicity-, Socioeconomic Status-, and Anatomic Subsite-Specific Risks for Gastric Cancer.

Gastroenterology 2019 01 26;156(1):59-62.e4. Epub 2018 Sep 26.

Moores Cancer Center, UC San Diego, La Jolla, California; Department of Family Medicine and Public Health, UC San Diego, La Jolla, California.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00165085183504
Publisher Site
http://dx.doi.org/10.1053/j.gastro.2018.09.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309455PMC
January 2019

Association Between Obesity and Discordance in Fibrosis Stage Determination by Magnetic Resonance vs Transient Elastography in Patients With Nonalcoholic Liver Disease.

Clin Gastroenterol Hepatol 2018 Dec 17;16(12):1974-1982.e7. Epub 2018 Jan 17.

NAFLD Research Center, Department of Medicine, University of California at San Diego, La Jolla, California; Division of Gastroenterology, Department of Medicine, University of California at San Diego, La Jolla, California; Division of Epidemiology, Department of Family and Preventive Medicine, University of California at San Diego, La Jolla, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cgh.2017.10.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050151PMC
December 2018

Magnetic Resonance Imaging Proton Density Fat Fraction Associates With Progression of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease.

Gastroenterology 2018 08 13;155(2):307-310.e2. Epub 2018 Apr 13.

NAFLD Research Center, Department of Medicine, University of California San Diego, La Jolla, California; Division of Gastroenterology, Department of Medicine, University of California at San Diego, La Jolla, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2018.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090543PMC
August 2018

Drug-Induced Liver Injury Associated with the Use of Everolimus in a Liver Transplant Patient.

Case Rep Transplant 2018 18;2018:7410508. Epub 2018 Jul 18.

University of California (UC) San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/7410508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076919PMC
July 2018

Biallelic Mismatch Repair Deficiency in an Adolescent Female.

Case Rep Genet 2018 25;2018:8657823. Epub 2018 Jul 25.

University of California San Diego Department of Pediatrics, Division of Gastroenterology, USA.

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/crig/2018/8657823/
Publisher Site
http://dx.doi.org/10.1155/2018/8657823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092986PMC
July 2018

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling.

Cancer Cell 2018 06;33(6):1061-1077.e6

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, School of Medicine, 9500 Gilman Drive, San Diego, CA 92093, USA; Department of Pathology, University of California San Diego, School of Medicine, 9500 Gilman Drive, San Diego, CA 92093, USA; Moores Cancer Center, University of California San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0723, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2018.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005359PMC
June 2018

Histologic Predictors of Recurrence in Mucinous Appendiceal Tumors with Peritoneal Dissemination after HIPEC.

Ann Surg Oncol 2018 Mar 27;25(3):702-708. Epub 2017 Dec 27.

Department of Surgery, Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Dr. #0987, La Jolla, CA, 92093-0987, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1245/s10434-017-6310-8
Publisher Site
http://dx.doi.org/10.1245/s10434-017-6310-8DOI Listing
March 2018

An Update on the Diagnosis, Grading, and Staging of Appendiceal Mucinous Neoplasms.

Adv Anat Pathol 2018 Jan;25(1):38-60

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAP.0000000000000178DOI Listing
January 2018

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

Cancer Cell 2017 Dec 16;32(6):824-839.e8. Epub 2017 Nov 16.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2017.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730340PMC
December 2017

Nonuterine Lipoleiomyoma.

Am Surg 2017 Dec;83(12):e474-475

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057751PMC
December 2017

Bullet fragment fiducials in stereotactic body radiotherapy as a bridge to transplant for hepatocellular carcinoma.

Acta Oncol 2017 10 12;56(10):1324-1327. Epub 2017 May 12.

b Department of Radiation Medicine and Applied Sciences , University of California San Diego , La Jolla , CA , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/0284186X.2017.1324208DOI Listing
October 2017

Vedolizumab in Patients With Common Variable Immune Deficiency and Gut Inflammation.

Am J Gastroenterol 2017 10;112(10):1621

Division of Gastroenterology, Inflammatory Bowel Disease Center, University of California San Diego, La Jolla, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ajg.2017.246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389596PMC
October 2017

Overinterpretation is common in pathological diagnosis of appendix cancer during patient referral for oncologic care.

PLoS One 2017 7;12(6):e0179216. Epub 2017 Jun 7.

Department of Surgery, Division of Surgical Oncology, University of California San Diego Moores Cancer Center, La Jolla, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179216PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462425PMC
September 2017

Gastric Medullary Carcinoma with Sporadic Mismatch Repair Deficiency and a R273C Mutation: An Unusual Case with Wild-Type .

Case Rep Pathol 2017 3;2017:3427343. Epub 2017 Aug 3.

Department of Pathology, University of California, San Diego, 200 West Arbor Drive, MC 8320, San Diego, CA 92103, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2017/3427343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559920PMC
August 2017

Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease.

Gastroenterology 2017 02 27;152(3):598-607.e2. Epub 2016 Oct 27.

Nonalcoholic Fatty Liver Disease Research Center, Department of Medicine, University of California at San Diego, La Jolla, California; Division of Gastroenterology, Department of Medicine, University of California at San Diego, La Jolla, California; Division of Epidemiology, Department of Family and Preventive Medicine, University of California at San Diego, La Jolla, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2016.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285304PMC
February 2017

Low-Grade Appendiceal Mucinous Neoplasm Involving the Endometrium and Presenting with Mucinous Vaginal Discharge.

Case Rep Obstet Gynecol 2016 23;2016:6841989. Epub 2016 Oct 23.

Department of Pathology, University of California San Diego, 200 W. Arbor Drive MC 8320, San Diego, CA 92103, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2016/6841989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097800PMC
October 2016

Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic Primaries.

Case Rep Pathol 2016 22;2016:1934759. Epub 2016 Sep 22.

Department of Pathology, University of California, San Diego, 200 West Arbor Drive, MC 8320, San Diego, CA 92103, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2016/1934759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055937PMC
September 2016

Helicobacter pylori Clarithromycin Resistance and Treatment Failure Are Common in the USA.

Dig Dis Sci 2016 08 29;61(8):2373-80. Epub 2016 Feb 29.

Department of Pathology, Virginia Commonwealth University Health System, Richmond, VA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10620-016-4091-8DOI Listing
August 2016

Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.

Cancer Discov 2016 08 13;6(8):870-85. Epub 2016 May 13.

Moores Cancer Center, University of California, San Diego, La Jolla, California. Department of Pathology, University of California, San Diego, La Jolla, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-15-1346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091937PMC
August 2016

p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells.

Cancer Cell 2016 06 19;29(6):935-948. Epub 2016 May 19.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA; Department of Pathology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2016.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907799PMC
June 2016

Cardiovascular risk assessment in the treatment of nonalcoholic steatohepatitis: a secondary analysis of the MOZART trial.

Therap Adv Gastroenterol 2016 Mar;9(2):152-61

Professor of Medicine and Associate Director of Clinical Research, Division of Gastroenterology, Adjunct Professor, Division of Epidemiology, University of California at San Diego, Biomedical Research Facility II, 4A18, 9500 Gilman Drive, La Jolla, CA 92093, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1756283X15621232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749859PMC
March 2016

Reproducibility of histological assessments of disease activity in UC.

Gut 2015 Nov 30;64(11):1765-73. Epub 2014 Oct 30.

Robarts Clinical Trials, Robarts Research Institute, Western University, London, Ontario, Canada Division of Gastroenterology, University of California San Diego, La Jolla, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/gutjnl-2014-307536DOI Listing
November 2015

Update on the Liver Imaging Reporting and Data System: What the Pathologist Needs to Know.

Adv Anat Pathol 2015 Sep;22(5):314-22

*Department of Radiology, Centre hospitalier de l'Université de Montréal (CHUM) †Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada ‡Department of Pathology §Liver Imaging Group, Department of Radiology, University of California, San Diego, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAP.0000000000000089DOI Listing
September 2015

Association Between Quantity of Liver Fat and Cardiovascular Risk in Patients With Nonalcoholic Fatty Liver Disease Independent of Nonalcoholic Steatohepatitis.

Clin Gastroenterol Hepatol 2015 Aug 3;13(8):1513-20.e1. Epub 2015 Feb 3.

NAFLD Translational Research Unit, Division of Gastroenterology, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California; Division of Epidemiology, Department of Family and Preventive Medicine, University of California San Diego School of Medicine, La Jolla, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cgh.2015.01.027DOI Listing
August 2015

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer.

Cell 2015 Aug;162(4):766-79

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA; Department of Pathology, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2015.07.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545590PMC
August 2015

Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial).

Hepatology 2015 Apr 27;61(4):1239-50. Epub 2015 Feb 27.

NAFLD Translational Research Unit, University of California at San Diego, La Jolla, CA; Division of Gastroenterology, Department of Medicine, University of California at San Diego, La Jolla, CA; Division of Epidemiology, Department of Family and Preventive Medicine, University of California at San Diego, La Jolla, CA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.27647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407930PMC
April 2015

Assessment of histologic disease activity in Crohn's disease: a systematic review.

Inflamm Bowel Dis 2014 Nov;20(11):2092-103

*Department of Medicine, Scripps Clinic, La Jolla, California; †Robarts Clinical Trials, Robarts Research Institute, Western University, London, ON, Canada; ‡Division of Gastroenterology, University of California San Diego, La Jolla, California; §Department of Gastroenterology, Academic Medical Center, Amsterdam, the Netherlands; ‖Departments of Medicine and Epidemiology and Biostatistics, Western University, London, Ontario, Canada; ¶Department of Pathology, University of California San Diego, La Jolla, CA; and **Department of Pathology, University Hospital of KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MIB.0000000000000155DOI Listing
November 2014

ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development.

Cancer Cell 2014 Sep 14;26(3):331-343. Epub 2014 Aug 14.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, San Diego, CA 92093, USA; Department of Pathology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, San Diego, CA 92093, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2014.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165611PMC
September 2014

Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition.

Cell Metab 2014 Jul 5;20(1):133-44. Epub 2014 Jun 5.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2014.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079758PMC
July 2014

The UPF1 RNA surveillance gene is commonly mutated in pancreatic adenosquamous carcinoma.

Nat Med 2014 Jun 25;20(6):596-8. Epub 2014 May 25.

Clinical and Translational Cancer Research Center, The Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.3548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048332PMC
June 2014

Sustained and selective suppression of intestinal cholesterol synthesis by Ro 48-8071, an inhibitor of 2,3-oxidosqualene:lanosterol cyclase, in the BALB/c mouse.

Biochem Pharmacol 2014 Apr 31;88(3):351-63. Epub 2014 Jan 31.

Departments of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2014.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989900PMC
April 2014

Paraneoplastic diarrhea in a patient with lung adenocarcinoma.

Clin J Gastroenterol 2013 Oct 26;6(5):357-60. Epub 2013 Jul 26.

Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390-9151, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12328-013-0407-9DOI Listing
October 2013

Prevalence of stimulant use in a sample of US medical students.

Ann Clin Psychiatry 2013 Feb;25(1):27-32

Yale Child Study Center, Yale School of Medicine, New Haven, CT, USA.

View Article

Download full-text PDF

Source
https://www.aacp.com/pdf%2F0213%2F0213ACP_Webb.pdf
Web Search
February 2013

Contemplating cognitive enhancement in medical students and residents.

Perspect Biol Med 2010 ;53(2):200-14

Medical Scientist Training Program, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1353/pbm.0.0154DOI Listing
November 2010

Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1.

Am J Physiol Gastrointest Liver Physiol 2010 Nov 19;299(5):G1012-22. Epub 2010 Aug 19.

Dept. of Internal Medicine, Univ. of Texas Southwestern Medical School, 5323 Harry Hines Blvd., Dallas, TX 75390-9151, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpgi.00190.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993165PMC
November 2010

Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters.

Am J Physiol Gastrointest Liver Physiol 2008 Oct 21;295(4):G813-22. Epub 2008 Aug 21.

Dept. of Internal Medicine, Univ. of Texas Southwestern Medical School, Dallas, TX 75390-9151, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpgi.90372.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575918PMC
October 2008

Fenofibrate reduces intestinal cholesterol absorption via PPARalpha-dependent modulation of NPC1L1 expression in mouse.

J Lipid Res 2007 Dec 28;48(12):2725-35. Epub 2007 Aug 28.

Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M700345-JLR200DOI Listing
December 2007

Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse.

J Neurosci 2007 Dec;27(52):14470-80

Department of Internal Medicine, University of Texas Southwestern Medical School, Dallas, Texas 75390-9151, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.4823-07.2007DOI Listing
December 2007

The power of real-time PCR.

Adv Physiol Educ 2005 Sep;29(3):151-9

Department of Physiology Touchstone Center for Diabetes Research, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8854, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/advan.00019.2005DOI Listing
September 2005

Caveolin-1 is not required for murine intestinal cholesterol transport.

J Biol Chem 2005 Jul 26;280(30):28103-9. Epub 2005 May 26.

Department of Physiology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M504609200DOI Listing
July 2005

Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.

Proc Natl Acad Sci U S A 2004 Jan 13;101(4):1045-50. Epub 2004 Jan 13.

Howard Hughes Medical Institute and Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9050, USA.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.2637002100
Publisher Site
http://dx.doi.org/10.1073/pnas.2637002100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC327148PMC
January 2004