Mark A Hanson

Mark A Hanson

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Mark A Hanson

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The prenatal embodiment of racial disparities.

Authors:
Mark A Hanson

Neurosci Biobehav Rev 2020 May 23;115:13-14. Epub 2020 May 23.

Institute of Developmental Sciences and NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2020.05.009DOI Listing
May 2020

Dynamic Evolution of Antimicrobial Peptides Underscores Trade-Offs Between Immunity and Ecological Fitness.

Front Immunol 2019 8;10:2620. Epub 2019 Nov 8.

Department of Molecular Biosciences, University of Kansas, Lawrence, KS, United States.

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http://dx.doi.org/10.3389/fimmu.2019.02620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857651PMC
November 2019

Niche Modification, Human Cultural Evolution and the Anthropocene.

Trends Ecol Evol 2019 10 15;34(10):883-885. Epub 2019 Aug 15.

Institute of Developmental Sciences, Faculty of Medicine, University Hospital Southampton, Mailpoint 887, Tremona Road, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1016/j.tree.2019.07.005DOI Listing
October 2019

Developing differences: early-life effects and evolutionary medicine.

Philos Trans R Soc Lond B Biol Sci 2019 04;374(1770):20190039

2 Centre for Ecology and Conservation , Penryn Campus, University of Exeter, Penryn TR10 IEZ , UK.

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http://dx.doi.org/10.1098/rstb.2019.0039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460072PMC
April 2019

Origins of lifetime health around the time of conception: causes and consequences.

Lancet 2018 05 16;391(10132):1842-1852. Epub 2018 Apr 16.

MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK; Institute of Developmental Sciences, University of Southampton, Southampton, UK; NIHR Southampton Biomedical Research Centre, University of Southampton & University Hospital Southampton NHS Foundation Trust, Southampton, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183031
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http://dx.doi.org/10.1016/S0140-6736(18)30312-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975952PMC
May 2018

Uncovering state-dependent relationships in shallow lakes using Bayesian latent variable regression.

Ecol Appl 2018 03 19;28(2):309-322. Epub 2018 Jan 19.

Department of Fisheries, Wildlife and Conservation Biology, University of Minnesota, St. Paul, Minnesota, 55108, USA.

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http://dx.doi.org/10.1002/eap.1645DOI Listing
March 2018

Transcriptome-wide analysis suggests that temporal changes in the relative contributions of hyperplasia, hypertrophy and apoptosis underlie liver growth in pregnant mice.

Biol Reprod 2017 Nov;97(5):762-771

Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1093/biolre/iox136DOI Listing
November 2017

Watershed vs. within-lake drivers of nitrogen: phosphorus dynamics in shallow lakes.

Ecol Appl 2017 10 7;27(7):2155-2169. Epub 2017 Sep 7.

Department of Ecology, Evolution, and Behavior, University of Minnesota, 1479 Gortner Avenue, St. Paul, Minnesota, 55108, USA.

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http://dx.doi.org/10.1002/eap.1599DOI Listing
October 2017

Avoidable early life environmental exposures.

Lancet Planet Health 2017 Aug 4;1(5):e172-e173. Epub 2017 Aug 4.

Department of Public Health, Environmental and Social Determinants of Health, World Health Organization, Geneva, Switzerland.

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http://dx.doi.org/10.1016/S2542-5196(17)30048-7DOI Listing
August 2017

ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity.

EBioMedicine 2017 May 26;19:60-72. Epub 2017 Apr 26.

NIHR Southampton Biomedical Research Centre, University of Southampton, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1016/j.ebiom.2017.03.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440605PMC
May 2017

The legacy of large regime shifts in shallow lakes.

Ecol Appl 2016 Dec 12;26(8):2660-2674. Epub 2016 Sep 12.

Department of Ecology, Evolution, and Behavior, University of Minnesota, 1479 Gortner Avenue, St. Paul, Minnesota, 55108, USA.

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http://dx.doi.org/10.1002/eap.1382DOI Listing
December 2016

Immune genes and divergent antimicrobial peptides in flies of the subgenus Drosophila.

BMC Evol Biol 2016 10 24;16(1):228. Epub 2016 Oct 24.

Department of Biology, University of Victoria, Victoria, BC, Canada.

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http://dx.doi.org/10.1186/s12862-016-0805-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078906PMC
October 2016

Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH.

Biochim Biophys Acta 2016 Jul 23;1861(7):584-93. Epub 2016 Apr 23.

Institute of Developmental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1016/j.bbalip.2016.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874946PMC
July 2016

A complex behavioural change intervention to reduce the risk of diabetes and prediabetes in the pre-conception period in Malaysia: study protocol for a randomised controlled trial.

Trials 2016 Apr 27;17(1):215. Epub 2016 Apr 27.

MRC Developmental Pathways for Health Research Unit, Department of Paediatrics, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1186/s13063-016-1345-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847351PMC
April 2016

Developmental origins of epigenetic transgenerational inheritance.

Environ Epigenet 2016;2(1). Epub 2016 Mar 6.

School of Biological Sciences, Center for Reproductive Biology, Washington State University, Pullman, WA 99164-4236, USA.

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http://dx.doi.org/10.1093/eep/dvw002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933018PMC
March 2016

Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast.

J Physiol 2015 Oct 9;593(20):4549-59. Epub 2015 Sep 9.

University of Southampton, Faculty of Medicine, Southampton General Hospital, Tremona Road, Southampton, UK.

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http://dx.doi.org/10.1113/JP270743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606536PMC
October 2015

Polyunsaturated fatty acid biosynthesis is involved in phenylephrine-mediated calcium release in vascular smooth muscle cells.

Prostaglandins Leukot Essent Fatty Acids 2015 Oct 20;101:31-9. Epub 2015 Aug 20.

Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK. Electronic address:

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http://dx.doi.org/10.1016/j.plefa.2015.08.001DOI Listing
October 2015

Maternal diabetes, gestational diabetes and the role of epigenetics in their long term effects on offspring.

Prog Biophys Mol Biol 2015 Jul 16;118(1-2):55-68. Epub 2015 Mar 16.

Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China.

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http://dx.doi.org/10.1016/j.pbiomolbio.2015.02.010DOI Listing
July 2015

Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms.

FASEB J 2015 Jun 11;29(6):2583-94. Epub 2015 Mar 11.

*Maternal and Fetal Health Research Centre, Institute of Human Development, University of Manchester, Manchester, United Kingdom; St. Mary's Hospital and Central Manchester University Hospitals National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom; Bioengineering Science Research Group, Faculty of Engineering and the Environment, University of Southampton, Southampton, United Kingdom; Mathematical Institute, Oxford University, Oxford, United Kingdom; and Faculty of Medicine, and Institute for Life Sciences, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1096/fj.14-267773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469330PMC
June 2015

Multi-Elements in Waters and Sediments of Shallow Lakes: Relationships with Water, Sediment, and Watershed Characteristics.

Wetlands (Wilmington) 2015 Jun;35(3):443-457

Wet Ecosystem Research Group, Department of Biological Sciences, North Dakota State University, NDSU Department 2715, P.O. Box 6050, Fargo, ND 58108-6050, USA.

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http://link.springer.com/content/pdf/10.1007%2Fs13157-015-06
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http://link.springer.com/10.1007/s13157-015-0632-8
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http://dx.doi.org/10.1007/s13157-015-0632-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460834PMC
June 2015

Genetics: Epigenetic mechanisms underlying type 2 diabetes mellitus.

Nat Rev Endocrinol 2015 May 10;11(5):261-2. Epub 2015 Mar 10.

MRC Lifecourse Epidemiology Unit, University of Southampton, University Road, Southampton SO17 1BJ, UK.

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http://dx.doi.org/10.1038/nrendo.2015.31DOI Listing
May 2015

Developmental origins of obesity and non-communicable disease.

Authors:
Mark A Hanson

Endocrinol Nutr 2013 ;60 Suppl 1:10-1

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http://dx.doi.org/10.1016/s1575-0922(13)70017-2DOI Listing
April 2015

Effect of maternal protein restriction during pregnancy and postweaning high-fat feeding on diet-induced thermogenesis in adult mouse offspring.

Eur J Nutr 2014 Oct 31;53(7):1523-31. Epub 2014 Jan 31.

Institute of Developmental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital (MP887), Southampton, SO16 6YD, UK.

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http://dx.doi.org/10.1007/s00394-014-0657-4DOI Listing
October 2014

Impaired cardiovascular structure and function in adult survivors of severe acute malnutrition.

Hypertension 2014 Sep 30;64(3):664-71. Epub 2014 Jun 30.

From the Tropical Medicine Research Institute (D.S.T., M.S.B.), Departments of Surgery, Radiology, Anaesthesia, and Intensive Care (I.A.T., A.T.B.), Medicine (Cardiology) (E.E.C., A.P.C.), and UWI Solutions for Developing Countries (T.E.F.), University of the West Indies, Mona, Kingston, Jamaica; Institute Biomedical Technology, Ghent University, Gent, Belgium (J.K., P.S.); MRC Lifecourse Epidemiology Unit (C.O.) and DOHAD Division (M.A.H.), University of Southampton, Southampton, United Kingdom; Centre for Human Evolution, Adaptation, and Disease, Liggins Institute, University of Auckland, Auckland, New Zealand (P.D.G.); and Division of Diabetes, Cardiovascular Medicine, and Nutrition, King's College and King's Health Partners, London, United Kingdom (J.K.C.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03230DOI Listing
September 2014

Glucose metabolism in adult survivors of severe acute malnutrition.

J Clin Endocrinol Metab 2014 Jun 11;99(6):2233-40. Epub 2014 Feb 11.

Tropical Medicine Research Institute (P.M.F.-E., D.S.T., A.T.B., T.E.F., M.S.B.) and Department of Surgery, Radiology, Anaesthesia, and Intensive Care (A.T.B.), The University of the West Indies, Mona, Kingston 7, Jamaica, West Indies; Medical Research Council Lifecourse Epidemiology Unit (C.O.), Institute of Developmental Sciences (M.A.H.) and Nutrition and Metabolism Unit (C.D.B.), School of Medicine, University of Southampton, Southampton SO16 6YD, United Kingdom; and Centre for Human Evolution, Adaptation, and Disease (P.D.G.), Liggins Institute, University of Auckland, Auckland 1142, New Zealand.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2013-3511DOI Listing
June 2014

Childhood bone mineral content is associated with methylation status of the RXRA promoter at birth.

J Bone Miner Res 2014 Mar;29(3):600-7

Medical Research Council (MRC) Lifecourse Epidemiology Unit, University of Southampton, UK; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service (NHS) Foundation Trust, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1002/jbmr.2056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836689PMC
March 2014

Tissue-specific 5' heterogeneity of PPARα transcripts and their differential regulation by leptin.

PLoS One 2013 25;8(6):e67483. Epub 2013 Jun 25.

Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067483PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692471PMC
February 2014

Relative importance of phosphorus, fish biomass, and watershed land use as drivers of phytoplankton abundance in shallow lakes.

Sci Total Environ 2014 Jan 25;466-467:849-55. Epub 2013 Aug 25.

Department of Biology, University of St. Thomas, St. Paul, MN, USA.

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http://dx.doi.org/10.1016/j.scitotenv.2013.07.106DOI Listing
January 2014

Non-imprinted epigenetics in fetal and postnatal development and growth.

Nestle Nutr Inst Workshop Ser 2013 22;71:57-63. Epub 2013 Jan 22.

MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1159/000342552DOI Listing
October 2013

Human growth: evolutionary and life history perspectives.

Nestle Nutr Inst Workshop Ser 2013 22;71:89-102. Epub 2013 Jan 22.

Centre for Human Evolution, Adaptation and Disease, Liggins Institute, The University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1159/000342572DOI Listing
October 2013

Gestational diabetes, maternal obesity, and the NCD burden.

Clin Obstet Gynecol 2013 Sep;56(3):633-41

Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1097/GRF.0b013e31829e5bb0DOI Listing
September 2013

Role of DNA methyltransferase 1 on the altered eNOS expression in human umbilical endothelium from intrauterine growth restricted fetuses.

Epigenetics 2013 Sep 18;8(9):944-52. Epub 2013 Jul 18.

Division of Obstetrics and Gynaecology; School of Medicine; Pontificia Universidad Católica de Chile; Santiago, Chile.

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http://dx.doi.org/10.4161/epi.25579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883771PMC
September 2013

Macrophytes in shallow lakes: relationships with water, sediment and watershed characteristics.

Aquat Bot 2013 Aug;109:39-48

Wet Ecosystem Research Group, Department of Biological Sciences, North Dakota State University, NDSU Department 2715, P.O. Box 6050, Fargo, ND 58108-6050.

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http://dx.doi.org/10.1016/j.aquabot.2013.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752979PMC
August 2013

Comparing effects of lake- and watershed-scale influences on communities of aquatic invertebrates in shallow lakes.

PLoS One 2012 6;7(9):e44644. Epub 2012 Sep 6.

Wetland Wildlife Populations and Research Group, Minnesota Department of Natural Resources, Bemidji, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044644PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435286PMC
March 2013

Early life opportunities for prevention of diabetes in low and middle income countries.

BMC Public Health 2012 Nov 23;12:1025. Epub 2012 Nov 23.

Institute of Developmental Sciences, Faculty of Medicine, University of Southampton, Mailpoint 887, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK.

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http://dx.doi.org/10.1186/1471-2458-12-1025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526388PMC
November 2012

Increasing the folic acid content of maternal or post-weaning diets induces differential changes in phosphoenolpyruvate carboxykinase mRNA expression and promoter methylation in rats.

Br J Nutr 2012 Sep 5;108(5):852-7. Epub 2011 Dec 5.

Academic Unit of Human Development and Health, Faculty of Medicine, Institute of Developmental Sciences, Southampton General Hospital, Tremona Road, Southampton, UK.

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http://dx.doi.org/10.1017/S0007114511006155DOI Listing
September 2012

A 200-year perspective on alternative stable state theory and lake management from a biomanipulated shallow lake.

Ecol Appl 2012 Jul;22(5):1483-96

St. Croix Watershed Research Station, Science Museum of Minnesota, Marine on St. Croix, Minnesota 55047, USA.

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http://dx.doi.org/10.1890/11-1485.1DOI Listing
July 2012

Associations between DNA methylation of a glucocorticoid receptor promoter and acute stress responses in a large healthy adult population are largely explained by lifestyle and educational differences.

Psychoneuroendocrinology 2012 Jun 5;37(6):782-8. Epub 2011 Oct 5.

Department of Clinical Epidemiology and Biostatistics, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.psyneuen.2011.09.010DOI Listing
June 2012

Progressive, transgenerational changes in offspring phenotype and epigenotype following nutritional transition.

PLoS One 2011 30;6(11):e28282. Epub 2011 Nov 30.

Academic Unit of Human Development and Health, Faculty of Medicine, Institute of Developmental Sciences, University of Southampton, Southampton General Hospital, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028282PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227644PMC
April 2012

Angiotensin II receptor antagonist reduces subsequent uterine arterial dysfunction in pregnant offspring of protein-restricted rat dams.

J Obstet Gynaecol Res 2012 Mar 16;38(3):483-9. Epub 2012 Feb 16.

Department of Obstetrics and Gynecology, School of Medicine, Juntendo University, Tokyo, Japan.

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http://doi.wiley.com/10.1111/j.1447-0756.2011.01737.x
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http://dx.doi.org/10.1111/j.1447-0756.2011.01737.xDOI Listing
March 2012

Dietary protein restriction during F0 pregnancy in rats induces transgenerational changes in the hepatic transcriptome in female offspring.

PLoS One 2011 7;6(7):e21668. Epub 2011 Jul 7.

Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Hampshire, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021668PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131279PMC
December 2011

Epigenetic epidemiology: the rebirth of soft inheritance.

Ann Nutr Metab 2011 12;58 Suppl 2:8-15. Epub 2011 Aug 12.

Institute of Developmental Sciences, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1159/000328033DOI Listing
December 2011

Developmental origins of health and disease: moving from biological concepts to interventions and policy.

Int J Gynaecol Obstet 2011 Nov;115 Suppl 1:S3-5

Institute of Developmental Sciences, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1016/S0020-7292(11)60003-9DOI Listing
November 2011

Umbilical venous-arterial plasma composition differences suggest differential incorporation of fatty acids in NEFA and cholesteryl ester pools.

Br J Nutr 2011 Aug 27;106(4):463-7. Epub 2011 Apr 27.

Institute of Developmental Sciences, Faculty of Medicine, University of Southampton, UK.

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http://dx.doi.org/10.1017/S0007114511000377DOI Listing
August 2011

Developmental plasticity and epigenetic mechanisms underpinning metabolic and cardiovascular diseases.

Epigenomics 2011 Jun;3(3):279-94

Liggins Institute, The University of Auckland, Auckland, New Zealand.

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https://www.futuremedicine.com/doi/10.2217/epi.11.17
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http://dx.doi.org/10.2217/epi.11.17DOI Listing
June 2011

The long-term effects of prenatal development on growth and metabolism.

Semin Reprod Med 2011 May 18;29(3):257-65. Epub 2011 Jul 18.

Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1055/s-0031-1275518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685133PMC
May 2011

Vascular, renal and placental effects on pregnant offspring of protein-restricted rat dams.

J Obstet Gynaecol Res 2011 Apr 27;37(4):343-51. Epub 2011 Jan 27.

Department of Obstetrics and Gynecology, School of Medicine, Juntendo University, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1447-0756.2010.01351.xDOI Listing
April 2011

Effect of sex and dietary fat intake on the fatty acid composition of phospholipids and triacylglycerol in rat heart.

Prostaglandins Leukot Essent Fatty Acids 2010 Oct-Dec;83(4-6):219-23. Epub 2010 Aug 16.

Institute of Human Nutrition, University of Southampton School of Medicine, Institute of Developmental Sciences Building, MP887, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1016/j.plefa.2010.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000522PMC
March 2011

How evolutionary principles improve the understanding of human health and disease.

Evol Appl 2011 Mar;4(2):249-63

Centre for Human Evolution, Adaptation and Disease, Liggins Institute, The University of Auckland Auckland, New Zealand.

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http://dx.doi.org/10.1111/j.1752-4571.2010.00164.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352556PMC
March 2011

The role of developmental plasticity and epigenetics in human health.

Birth Defects Res C Embryo Today 2011 Mar;93(1):12-8

Centre for Human Evolution, Adaptation and Disease, Liggins Institute, The University of Auckland, New Zealand.

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http://dx.doi.org/10.1002/bdrc.20198DOI Listing
March 2011

Developmental origins of the metabolic syndrome: body clocks and stress responses.

Brain Behav Immun 2011 Feb 17;25(2):214-20. Epub 2010 Sep 17.

Institute of Developmental Sciences, School of Medicine, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1016/j.bbi.2010.09.005DOI Listing
February 2011

Maternal protein restriction with or without folic acid supplementation during pregnancy alters the hepatic transcriptome in adult male rats.

Br J Nutr 2010 Jun 9;103(12):1711-9. Epub 2010 Mar 9.

Development and Cell Biology, University of Southampton, Bassett Crescent East, Southampton, UK.

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http://dx.doi.org/10.1017/S0007114509993795DOI Listing
June 2010

Sex- and age-specific effects of nutrition in early gestation and early postnatal life on hypothalamo-pituitary-adrenal axis and sympathoadrenal function in adult sheep.

J Physiol 2010 Jun 26;588(Pt 12):2219-37. Epub 2010 Apr 26.

Institute of Developmental Sciences, Developmental Origins of Health and Disease Division, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1113/jphysiol.2010.187682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911222PMC
June 2010

Developmental origins of metabolic disease: life course and intergenerational perspectives.

Trends Endocrinol Metab 2010 Apr 14;21(4):199-205. Epub 2010 Jan 14.

University of Southampton School of Medicine, Southampton, UK.

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http://dx.doi.org/10.1016/j.tem.2009.12.008DOI Listing
April 2010

The developmental origins, mechanisms, and implications of metabolic syndrome.

J Nutr 2010 Mar 27;140(3):648-52. Epub 2010 Jan 27.

Developmental Origins of Health and Disease Division, Institute of Developmental Sciences, University of Southampton School of Medicine, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.3945/jn.109.111179DOI Listing
March 2010

Developmental origins of health and disease: reducing the burden of chronic disease in the next generation.

Genome Med 2010 Feb 24;2(2):14. Epub 2010 Feb 24.

Liggins Institute, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.

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http://dx.doi.org/10.1186/gm135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847705PMC
February 2010

Redistribution pattern of fetal liver circulation in intrauterine growth restriction.

Acta Obstet Gynecol Scand 2009 ;88(10):1118-23

Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.

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http://dx.doi.org/10.1080/00016340903214924DOI Listing
December 2009

Effects of pre- and periconceptional undernutrition on arterial function in adult female sheep are vascular bed dependent.

Exp Physiol 2009 Sep 26;94(9):1024-33. Epub 2009 Jun 26.

Institute of Developmental Sciences, School of Medicine, University of Southampton, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1113/expphysiol.2009.047340DOI Listing
September 2009

Long-term maternal high-fat feeding from weaning through pregnancy and lactation predisposes offspring to hypertension, raised plasma lipids and fatty liver in mice.

Br J Nutr 2009 Aug 10;102(4):514-9. Epub 2009 Feb 10.

Institute of Developmental Sciences, Developmental Origins of Health and Disease Division, University of Southampton School of Medicine, Southampton General Hospital, Mailpoint 887, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1017/S000711450820749XDOI Listing
August 2009

Epigenetic mechanisms that underpin metabolic and cardiovascular diseases.

Nat Rev Endocrinol 2009 Jul 2;5(7):401-8. Epub 2009 Jun 2.

Centre for Human Evolution, Adaptation and Disease, Liggins Institute, The University of Auckland, New Zealand.

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http://www.nature.com/articles/nrendo.2009.102
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http://dx.doi.org/10.1038/nrendo.2009.102DOI Listing
July 2009

Fetal superior mesenteric artery: longitudinal reference ranges and evidence of regulatory link to portal liver circulation.

Early Hum Dev 2009 Apr 13;85(4):207-13. Epub 2008 Nov 13.

Department of Obsterics and Gynecology, Haukeland University Hospital, N-5021 Bergen, Norway.

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http://dx.doi.org/10.1016/j.earlhumdev.2008.09.412DOI Listing
April 2009

Atorvastatin restores endothelial function in offspring of protein-restricted rats in a cholesterol-independent manner.

Hypertension 2009 Apr 16;53(4):661-7. Epub 2009 Feb 16.

Vascular Biology Group, Institute of Developmental Sciences (887), University of Southampton, School of Medicine, Southampton General Hospital, Tremona Rd, Southampton S016 6YD, United Kingdom.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.108.122820DOI Listing
April 2009

The late gestation fetal cardiovascular response to hypoglycaemia is modified by prior peri-implantation undernutrition in sheep.

J Physiol 2009 Feb 22;587(3):611-24. Epub 2008 Dec 22.

Institute of Developmental Sciences, Southampton General Hospital, Tremona Road, Southampton, UK.

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http://dx.doi.org/10.1113/jphysiol.2008.165944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670084PMC
February 2009

Maternal undernutrition leads to endothelial dysfunction in adult male rat offspring independent of postnatal diet.

Br J Nutr 2009 Jan 20;101(1):27-33. Epub 2008 May 20.

Liggins Institute, Faculty of Medical and Health Science, University of Auckland and National Research Centre for Growth and Development, Auckland, New Zealand.

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http://dx.doi.org/10.1017/S0007114508988760DOI Listing
January 2009

Association of adult height and leg length with fasting plasma cortisol concentrations: evidence for an effect of normal variation in adrenocortical activity on growth.

Am J Hum Biol 2008 Nov-Dec;20(6):712-5

MRC Epidemiology Resource Centre, Mpt 95, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1002/ajhb.20803DOI Listing
January 2009

Sensitivity of housekeeping genes in the hypothalamus to mismatch in diets between pre- and postnatal periods in mice.

Neurosci Lett 2008 Dec 27;447(1):54-7. Epub 2008 Sep 27.

Developmental Origins of Health & Disease Division, Institute of Developmental Sciences, University of Southampton School of Medicine, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.neulet.2008.09.060DOI Listing
December 2008

Developmental perspectives on individual variation: implications for understanding nutritional needs.

Nestle Nutr Workshop Ser Pediatr Program 2008 ;62:1-9; disucssion 9-12

Liggins Institute, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1159/000146243DOI Listing
November 2008

Transmission of raised blood pressure and endothelial dysfunction to the F2 generation induced by maternal protein restriction in the F0, in the absence of dietary challenge in the F1 generation.

Br J Nutr 2008 Oct 28;100(4):760-6. Epub 2008 Feb 28.

Maternal, Fetal and Neonatal Physiology, Institute of Developmental Sciences, School of Medicine, University of Southampton, Southampton General Hospital, Tremona Road, Southampton SO166YD, UK.

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http://dx.doi.org/10.1017/S0007114508921747DOI Listing
October 2008

Appetite regulatory mechanisms and food intake in mice are sensitive to mismatch in diets between pregnancy and postnatal periods.

Brain Res 2008 Oct 13;1237:146-52. Epub 2008 Aug 13.

Institute of Developmental Sciences, Developmental Origins of Health and Disease Division, University of Southampton School of Medicine, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1016/j.brainres.2008.07.126DOI Listing
October 2008

Predictive adaptive responses in perspective.

Trends Endocrinol Metab 2008 May-Jun;19(4):109-10; author reply 112. Epub 2008 Mar 6.

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http://dx.doi.org/10.1016/j.tem.2008.02.002DOI Listing
July 2008

Effect of in utero and early-life conditions on adult health and disease.

N Engl J Med 2008 Jul;359(1):61-73

Liggins Institute, University of Auckland, and National Research Centre for Growth and Development, Auckland, New Zealand.

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http://dx.doi.org/10.1056/NEJMra0708473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923653PMC
July 2008

Peri-implantation and late gestation maternal undernutrition differentially affect fetal sheep skeletal muscle development.

J Physiol 2008 May 13;586(9):2371-9. Epub 2008 Mar 13.

Institute of Developmental Sciences, Developmental Origins of Health and Disease Division, MP 887, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1113/jphysiol.2008.150987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2479554PMC
May 2008

Transgenerational effects of prenatal nutrient restriction on cardiovascular and hypothalamic-pituitary-adrenal function.

J Physiol 2008 Apr 21;586(8):2217-29. Epub 2008 Feb 21.

1Centre for Developmental Origins of Health and Disease, Princess Anne Hospital, Coxford Road, Southampton SO16 5YA, UK.

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http://doi.wiley.com/10.1113/jphysiol.2007.147967
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2465204PMC
April 2008