Mark A Hancock

Mark A Hancock

UNVERIFIED PROFILE

Are you Mark A Hancock?   Register this Author

Register author
Mark A Hancock

Mark A Hancock

Publications by authors named "Mark A Hancock"

Are you Mark A Hancock?   Register this Author

38Publications

418Reads

16Profile Views

Label-free distribution of anti-amyloid D-AIP in Drosophila melanogaster: prevention of Aβ42-induced toxicity without side effects in transgenic flies.

J Neurochem 2019 May 11. Epub 2019 May 11.

Department of Pharmacology & Therapeutics, Life Sciences Complex, McGill University, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jnc.14720DOI Listing
May 2019

Neurodegenerative Disease-Related Proteins within the Epidermal Layer of the Human Skin.

J Alzheimers Dis 2019 ;69(2):463-478

Department of Pharmacology & Therapeutics, Life Sciences Complex, McGill University, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-181191DOI Listing
January 2019

Staphylococcal Superantigens Use LAMA2 as a Coreceptor To Activate T Cells.

J Immunol 2018 02 15;200(4):1471-1479. Epub 2018 Jan 15.

Microbiome and Disease Tolerance Centre, Department of Microbiology and Immunology, McGill University, Montreal, Quebec H3A 2B4, Canada;

View Article

Download full-text PDF

Source
http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1701212
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1701212DOI Listing
February 2018

Development of DNA Nanostructures for High-Affinity Binding to Human Serum Albumin.

J Am Chem Soc 2017 05 18;139(21):7355-7362. Epub 2017 May 18.

Department of Chemistry and Centre for Self-Assembled Chemical Structures (CSACS), McGill University , 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.7b02917DOI Listing
May 2017

Structural Analysis and Inhibition of TraE from the pKM101 Type IV Secretion System.

J Biol Chem 2016 Nov 15;291(45):23817-23829. Epub 2016 Sep 15.

From the Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, Quebec H3C 3J7, Canada, and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M116.753327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095433PMC
November 2016

Soluble CD109 binds TGF-β and antagonizes TGF-β signalling and responses.

Biochem J 2016 Mar 30;473(5):537-47. Epub 2015 Nov 30.

Division of Plastic Surgery, Department of Surgery, McGill University Health Centre, Montreal, QC, Canada, H3G1A4

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20141488DOI Listing
March 2016

Purification and interaction analyses of two human lysosomal vitamin B12 transporters: LMBD1 and ABCD4.

Mol Membr Biol 2014 Nov-Dec;31(7-8):250-61

Department of Microbiology and Immunology, McGill University , Montreal , Canada .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/09687688.2014.990998DOI Listing
August 2015

Ivermectin binds to Haemonchus contortus tubulins and promotes stability of microtubules.

Int J Parasitol 2015 Aug 5;45(9-10):647-54. Epub 2015 May 5.

Institute of Parasitology, McGill University-Macdonald Campus, Sainte-Anne-de-Bellevue, Quebec, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpara.2015.03.010DOI Listing
August 2015

The IGF-Trap: Novel Inhibitor of Carcinoma Growth and Metastasis.

Mol Cancer Ther 2015 Apr 11;14(4):982-93. Epub 2015 Feb 11.

Department of Surgery, McGill University Health Centre, McGill University, Montreal, Québec, Canada. Department of Medicine, McGill University Health Centre, McGill University, Montreal, Québec, Canada. Department of Oncology, McGill University Health Centre, McGill University, Montreal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-14-0751DOI Listing
April 2015

Leucine-responsive regulatory protein Lrp and PapI homologues influence phase variation of CS31A fimbriae.

J Bacteriol 2014 Aug 9;196(16):2944-53. Epub 2014 Jun 9.

Groupe de Recherche sur les Maladies Infectieuses du Porc (GREMIP) and Centre de Recherche en Infectiologie Porcine (CRIP), Université de Montréal, Saint-Hyacinthe, Quebec, Canada

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JB.01622-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135631PMC
August 2014

Novel zinc-binding site in the E2 domain regulates amyloid precursor-like protein 1 (APLP1) oligomerization.

J Biol Chem 2014 Jul 22;289(27):19019-30. Epub 2014 May 22.

From the Institut für Chemie und Biochemie, Freie Universität Berlin, Thielallee 63, 14195 Berlin, Germany, the Department of Pharmacology and Therapeutics, McGill University Montreal, Montreal, Quebec H3G 1Y6, Canada,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M114.570382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081940PMC
July 2014

An immunogenic peptide in the A-box of HMGB1 protein reverses apoptosis-induced tolerance through RAGE receptor.

J Biol Chem 2014 Mar 28;289(11):7777-86. Epub 2014 Jan 28.

From the Department of Microbiology and Immunology, SPR Facility, Department of Biochemistry and Department of Medicine, McGill University, Montreal, Quebec H3G 0B1, Canada.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M113.541474
Publisher Site
http://dx.doi.org/10.1074/jbc.M113.541474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953289PMC
March 2014

Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells.

Cell Signal 2013 Dec 7;25(12):2717-26. Epub 2013 Sep 7.

Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellsig.2013.09.002DOI Listing
December 2013

A platinum(II) phenylphenanthroimidazole with an extended side-chain exhibits slow dissociation from a c-Kit G-quadruplex motif.

Chemistry 2013 Dec 18;19(52):17836-45. Epub 2013 Nov 18.

McGill University Department of Chemistry, 801 Sherbrooke West, Montreal, Quebec, H3A 0B8 (Canada).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/chem.201301590DOI Listing
December 2013

Structural features of recombinant MMADHC isoforms and their interactions with MMACHC, proteins of mammalian vitamin B12 metabolism.

Mol Genet Metab 2012 Nov 11;107(3):352-62. Epub 2012 Jul 11.

Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymgme.2012.07.001DOI Listing
November 2012

Biochemical and biological characterization of Escherichia coli STb His12 to Asn variant.

Toxicon 2012 Feb 1;59(2):300-5. Epub 2011 Dec 1.

Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, 3200 rue Sicotte, Saint-Hyacinthe, Québec, Canada J2S 7C6.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxicon.2011.11.015DOI Listing
February 2012

Lrp-DNA complex stability determines the level of ON cells in type P fimbriae phase variation.

Mol Microbiol 2011 Sep 20;81(5):1286-99. Epub 2011 Jul 20.

Groupe de Recherche sur les Maladies Infectieuses du Porc and Centre de Recherche en Infectiologie Porcine, Université de Montréal, Saint-Hyacinthe, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2958.2011.07761.xDOI Listing
September 2011

Binding between insulin-like growth factor 1 and insulin-like growth factor-binding protein 3 is not influenced by glucose or 2-deoxy-D-glucose.

J Biol Chem 2011 May 9;286(19):16567-73. Epub 2011 Mar 9.

Segal Cancer Centre and Lady Davis Institute of the Jewish General Hospital, Montreal, Quebec H3T 1E2, Canada.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M110.213033
Publisher Site
http://dx.doi.org/10.1074/jbc.M110.213033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089499PMC
May 2011

Interaction between MMACHC and MMADHC, two human proteins participating in intracellular vitamin B₁₂ metabolism.

Mol Genet Metab 2011 Feb 21;102(2):139-48. Epub 2010 Oct 21.

Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymgme.2010.10.011DOI Listing
February 2011

Quantitative analysis of VirB8-VirB9-VirB10 interactions provides a dynamic model of type IV secretion system core complex assembly.

Biochemistry 2010 Jun;49(21):4483-93

Department of Biology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi902201yDOI Listing
June 2010

Conformation change in a self-recognizing autotransporter modulates bacterial cell-cell interaction.

J Biol Chem 2010 Apr 1;285(14):10616-26. Epub 2010 Feb 1.

Canada Research Chair on Bacterial Animal Diseases, Université de Montréal, Saint-Hyacinthe, Québec J2S 7C6, Canaada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.069070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856270PMC
April 2010

TonB interacts with BtuF, the Escherichia coli periplasmic binding protein for cyanocobalamin.

Biochemistry 2009 Oct;48(39):9212-20

Department of Microbiology and Immunology, McGill University, 3775 University Street,Montreal, Quebec, Canada H3A 2B4.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi900722pDOI Listing
October 2009

TonB induces conformational changes in surface-exposed loops of FhuA, outer membrane receptor of Escherichia coli.

Protein Sci 2008 Oct 24;17(10):1679-88. Epub 2008 Jul 24.

Department of Microbiology and Immunology, McGill University, Montreal, Quebec H3A 2B4, Canada.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1110/ps.036244.108
Publisher Site
http://dx.doi.org/10.1110/ps.036244.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2548371PMC
October 2008

Mutation in the LPS outer core biosynthesis gene, galU, affects LPS interaction with the RTX toxins ApxI and ApxII and cytolytic activity of Actinobacillus pleuropneumoniae serotype 1.

Mol Microbiol 2008 Oct 18;70(1):221-35. Epub 2008 Aug 18.

Groupe de recherche sur les maladies infectieuses du porc, Faculté de médecine vétérinaire, Université de Montréal, St-Hyacinthe, QC, Canada J2S 7C6.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2958.2008.06409.xDOI Listing
October 2008

Isolation and characterization of alpha-enolase, a novel fibronectin-binding protein from Streptococcus suis.

Microbiology 2008 Sep;154(Pt 9):2668-79

Groupe de Recherche sur les Maladies Infectieuses du Porc (GREMIP) and Centre de Recherche en Infectiologie Porcine (CRIP), Faculté de Médecine Vétérinaire, Université de Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://mic.microbiologyresearch.org/content/journal/micro/10
Publisher Site
http://dx.doi.org/10.1099/mic.0.2008/017145-0DOI Listing
September 2008

The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures.

Mol Biol Cell 2007 Sep 20;18(9):3225-36. Epub 2007 Jun 20.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, H3A 2B4, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.e07-05-0404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1951767PMC
September 2007

Plasminogen binds to plasmin-modulated factor Xa by Ca(2+) - and C-terminal lysine-dependent and -independent interactions.

Thromb Haemost 2007 Jan;97(1):38-44

Canadian Blood Services, R&D Department, University of British Columbia/Centre for Blood Research, Department of Pathology and Laboratory Medicine, Vancouver.

View Article

Download full-text PDF

Source
January 2007

Interactions between TonB from Escherichia coli and the periplasmic protein FhuD.

J Biol Chem 2006 Nov 23;281(46):35413-24. Epub 2006 Aug 23.

Department of Microbiology and Immunology, and Sheldon Biotechnology Centre, McGill University, Montreal, Quebec H3A 2B4, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M607611200DOI Listing
November 2006

Definition of the structural elements in plasminogen required for high-affinity binding to apolipoprotein(a): a study utilizing surface plasmon resonance.

Biochemistry 2004 Sep;43(38):12237-48

Department of Biochemistry, Queen's University, Kingston, Ontario, Canada K7L 3N6.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/bi048756o
Publisher Site
http://dx.doi.org/10.1021/bi048756oDOI Listing
September 2004