Publications by authors named "Mark A Atkinson"

99Publications

Organisation of the human pancreas in health and in diabetes.

Diabetologia 2020 Oct 7;63(10):1966-1973. Epub 2020 Sep 7.

Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s00125-020-05203-7DOI Listing
October 2020

Removing Formaldehyde-Induced Peptidyl Crosslinks Enables Mass Spectrometry Imaging of Peptide Hormone Distributions from Formalin-Fixed Paraffin-Embedded Tissues.

Angew Chem Int Ed Engl 2020 Aug 6. Epub 2020 Aug 6.

University of Illinois, Department of Chemistry, 600 S. Mathews Ave. 63-5, 61801-5004, Urbana, UNITED STATES.

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http://dx.doi.org/10.1002/anie.202008847DOI Listing
August 2020

Large-scale electron microscopy database for human type 1 diabetes.

Nat Commun 2020 05 18;11(1):2475. Epub 2020 May 18.

Department of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/s41467-020-16287-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235089PMC
May 2020

Commercially Available Insulin Products Demonstrate Stability Throughout the Cold Supply Chain Across the U.S.

Diabetes Care 2020 Jun 9;43(6):1360-1362. Epub 2020 Apr 9.

Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL.

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http://dx.doi.org/10.2337/dc19-1941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245346PMC
June 2020

Obesity Treatment Among Adolescents: A Review of Current Evidence and Future Directions.

JAMA Pediatr 2020 Jun;174(6):609-617

Center for Pediatric Obesity Medicine, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota.

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http://dx.doi.org/10.1001/jamapediatrics.2020.0085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483247PMC
June 2020

Innate inflammation drives NK cell activation to impair Treg activity.

J Autoimmun 2020 Mar 6;108:102417. Epub 2020 Feb 6.

Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, USA; Department of Pediatrics, University of Florida, Gainesville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2020.102417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086400PMC
March 2020

Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation.

Cell Rep 2019 12;29(10):3073-3086.e5

Department of Microbiology and Immunology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA; Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA; Max McGee National Research Center for Juvenile Diabetes, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914223PMC
December 2019

Research digest: pioneering an oral GLP-1 receptor agonist.

Lancet Diabetes Endocrinol 2019 12 6;7(12):897. Epub 2019 Nov 6.

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http://dx.doi.org/10.1016/S2213-8587(19)30360-2DOI Listing
December 2019

Genetic risk for autoimmunity is associated with distinct changes in the human gut microbiome.

Nat Commun 2019 08 9;10(1):3621. Epub 2019 Aug 9.

Crown Princess Victoria's Children's Hospital, Region Östergötland, Division of Pediatrics, Linköping University, Linköping, SE 58185, Sweden.

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http://dx.doi.org/10.1038/s41467-019-11460-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689114PMC
August 2019

Pleiotropic roles of the insulin-like growth factor axis in type 1 diabetes.

Curr Opin Endocrinol Diabetes Obes 2019 08;26(4):188-194

Department of Pathology, Immunology, and Laboratory Medicine.

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http://dx.doi.org/10.1097/MED.0000000000000484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135378PMC
August 2019

NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP).

Diabetes 2019 07 24;68(7):1394-1402. Epub 2019 May 24.

Departments of Pathology and Pediatrics, University of Florida Diabetes Institute, Gainesville, FL.

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http://dx.doi.org/10.2337/db19-0058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609987PMC
July 2019

Islet amyloidosis in a child with type 1 diabetes.

Islets 2019 14;11(2):44-49. Epub 2019 May 14.

a Departments of Pathology, Immunology, and Laboratory Medicine , University of Florida , Gainesville , FL , USA.

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http://dx.doi.org/10.1080/19382014.2019.1599707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548483PMC
December 2019

Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the A obesity-associated gene.

Sci Rep 2019 03 12;9(1):4269. Epub 2019 Mar 12.

Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA, 90095-1735, United States.

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http://dx.doi.org/10.1038/s41598-019-38905-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414670PMC
March 2019

Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes.

Cell Metab 2019 03 31;29(3):769-783.e4. Epub 2019 Jan 31.

Department of Genetics and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436557PMC
March 2019

Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.

Front Endocrinol (Lausanne) 2018 9;9:791. Epub 2019 Jan 9.

Larry L. Hillblom Islet Research Center, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA, United States.

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http://dx.doi.org/10.3389/fendo.2018.00791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334491PMC
January 2019

The challenge of modulating β-cell autoimmunity in type 1 diabetes.

Lancet Diabetes Endocrinol 2019 01 24;7(1):52-64. Epub 2018 Oct 24.

Peter Gorer Department of Immunobiology, Faculty of Life Sciences & Medicine, King's College London, London, UK; King's Health Partners Institute of Diabetes, Obesity and Endocrinology, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S22138587183011
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http://dx.doi.org/10.1016/S2213-8587(18)30112-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322790PMC
January 2019

Nanowell-mediated two-dimensional liquid chromatography enables deep proteome profiling of <1000 mammalian cells.

Chem Sci 2018 Sep 18;9(34):6944-6951. Epub 2018 Jul 18.

Environmental Molecular Sciences Laboratory , Pacific Northwest National Laboratory , Richland , WA 99354 , USA . Email:

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http://dx.doi.org/10.1039/c8sc02680gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124911PMC
September 2018

How social is social inhibition of return?

Atten Percept Psychophys 2018 Nov;80(8):1892-1903

Department of Psychology and Centre for Brain Science, University of Essex, Exeter, UK.

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http://dx.doi.org/10.3758/s13414-018-1546-3DOI Listing
November 2018

Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus.

Front Immunol 2018 9;9:1053. Epub 2018 May 9.

Department of Pathology, Immunology, Laboratory Medicine, University of Florida Diabetes Institute, University of Florida, Gainesville, FL, United States.

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http://dx.doi.org/10.3389/fimmu.2018.01053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954343PMC
July 2019

Islet Microvasculature Alterations With Loss of Beta-cells in Patients With Type 1 Diabetes.

J Histochem Cytochem 2019 01 17;67(1):41-52. Epub 2018 May 17.

Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida.

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http://journals.sagepub.com/doi/10.1369/0022155418778546
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http://dx.doi.org/10.1369/0022155418778546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309032PMC
January 2019

Loss of B-Cell Anergy in Type 1 Diabetes Is Associated With High-Risk HLA and Non-HLA Disease Susceptibility Alleles.

Diabetes 2018 04 17;67(4):697-703. Epub 2018 Jan 17.

Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO

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http://dx.doi.org/10.2337/db17-0937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860860PMC
April 2018

Hospital time prior to death and pancreas histopathology: implications for future studies.

Diabetologia 2018 04 11;61(4):954-958. Epub 2017 Nov 11.

Department of Diabetes and Cancer Discovery Science, Diabetes and Metabolism Research Institute, City of Hope/Beckman Research Institute, 1500 East Duarte Road, Duarte, CA, 91010-3000, USA.

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http://dx.doi.org/10.1007/s00125-017-4494-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844815PMC
April 2018

T cells display mitochondria hyperpolarization in human type 1 diabetes.

Sci Rep 2017 09 7;7(1):10835. Epub 2017 Sep 7.

Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1038/s41598-017-11056-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589742PMC
September 2017

Type 1 Interferons Potentiate Human CD8 T-Cell Cytotoxicity Through a STAT4- and Granzyme B-Dependent Pathway.

Diabetes 2017 12 6;66(12):3061-3071. Epub 2017 Sep 6.

Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL

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http://dx.doi.org/10.2337/db17-0106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697952PMC
December 2017

Proteoliposome-based full-length ZnT8 self-antigen for type 1 diabetes diagnosis on a plasmonic platform.

Proc Natl Acad Sci U S A 2017 09 5;114(38):10196-10201. Epub 2017 Sep 5.

Department of Chemistry, Bio-X, and the Biophysics Program, Stanford University, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1711169114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617307PMC
September 2017

Untargeted metabolomic analysis in naturally occurring canine diabetes mellitus identifies similarities to human Type 1 Diabetes.

Sci Rep 2017 08 25;7(1):9467. Epub 2017 Aug 25.

Department of Pathology, Immunology, and Laboratory Medicine, The University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1038/s41598-017-09908-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573354PMC
August 2017

Impact of blood collection and processing on peripheral blood gene expression profiling in type 1 diabetes.

BMC Genomics 2017 Aug 18;18(1):636. Epub 2017 Aug 18.

Department of Medicine, Division of Immunology and Rheumatology, Stanford University, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1186/s12864-017-3949-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563008PMC
August 2017

Visual attention and action: How cueing, direct mapping, and social interactions drive orienting.

Psychon Bull Rev 2018 Oct;25(5):1585-1605

Department of Psychology and Centre for Brain Science, University of Essex, Colchester, UK.

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http://dx.doi.org/10.3758/s13423-017-1354-0DOI Listing
October 2018

N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults.

Front Immunol 2017 12;8:655. Epub 2017 Jun 12.

Department of Microbiology and Cell Science, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.

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http://dx.doi.org/10.3389/fimmu.2017.00655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466969PMC
June 2017

Spontaneous Perspective Taking in Humans?

Vision (Basel) 2017 Jun 16;1(2). Epub 2017 Jun 16.

Department of Psychology, University of Durham, Durham DH1 3HP, UK.

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http://dx.doi.org/10.3390/vision1020017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835973PMC
June 2017

Are goal states represented during kinematic imitation?

J Exp Psychol Hum Percept Perform 2018 Feb 29;44(2):226-242. Epub 2017 May 29.

Department of Psychology, University of Hull.

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http://dx.doi.org/10.1037/xhp0000429DOI Listing
February 2018

Mary Tyler Moore (1936-2017): Diabetes Educator and Advocate.

Diabetes Care 2017 06;40(6):732-735

Past Senior Director, International Partnerships and Cure Therapeutics, JDRF, New York, NY.

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http://dx.doi.org/10.2337/dci17-0015DOI Listing
June 2017

Plant-based vaccines for oral delivery of type 1 diabetes-related autoantigens: Evaluating oral tolerance mechanisms and disease prevention in NOD mice.

Sci Rep 2017 02 13;7:42372. Epub 2017 Feb 13.

Departments of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1038/srep42372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304332PMC
February 2017

Serum Trypsinogen Levels in Type 1 Diabetes.

Diabetes Care 2017 Apr 23;40(4):577-582. Epub 2017 Jan 23.

Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL

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http://dx.doi.org/10.2337/dc16-1774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360284PMC
April 2017

Factors That Influence the Quality of RNA From the Pancreas of Organ Donors.

Pancreas 2017 02;46(2):252-259

From the *Departments of Pathology, Immunology, & Laboratory Medicine, University of Florida, Gainesville, FL; †Department of Medicine, College of Medicine, University of Tennessee Health Science Center, Memphis, TN; ‡Diabetes Research Institute and Departments of Medicine, Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL; §Department of Information Sciences, ∥Division of Biostatistics, City of Hope, Duarte, CA; and ¶Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL.

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http://dx.doi.org/10.1097/MPA.0000000000000717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235995PMC
February 2017

Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease.

Diabetes 2016 11;65(11):3233-3239

Departments of Pathology and Pediatrics, UF Diabetes Institute, University of Florida, Gainesville, FL

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http://dx.doi.org/10.2337/db16-0687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860440PMC
November 2016

Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes.

Diabetologia 2016 11 9;59(11):2448-2458. Epub 2016 Aug 9.

Islet Biology Exeter (IBEx), Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, RILD Building (Level 4), Barrack Road, Exeter, EX2 5DW, UK.

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http://dx.doi.org/10.1007/s00125-016-4067-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042874PMC
November 2016

Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis.

Hum Pathol 2016 10 21;56:93-100. Epub 2016 Jun 21.

Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; Department of Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2016.06.006DOI Listing
October 2016

Presumptive Type 1 Diabetes With Comorbidities and Rapid Progression Despite Numerous Insulin-Positive Islets.

Diabetes Care 2016 07;39(7):1292-4

Department of Pediatrics, University of Florida, Gainesville, FL

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http://dx.doi.org/10.2337/dc16-0737DOI Listing
July 2016

Sulfatide Preserves Insulin Crystals Not by Being Integrated in the Lattice but by Stabilizing Their Surface.

J Diabetes Res 2016 14;2016:6179635. Epub 2016 Feb 14.

Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, 1600 SW Archer Road, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1155/2016/6179635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769769PMC
December 2016

Type 1 diabetes cadaveric human pancreata exhibit a unique exocrine tissue proteomic profile.

Proteomics 2016 05 13;16(9):1432-46. Epub 2016 Apr 13.

Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, NC, USA.

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http://dx.doi.org/10.1002/pmic.201500333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893790PMC
May 2016

Pancreatic duct hyperplasia/dysplasia in type 1 diabetes and pancreatic weight in individuals with and without diabetes. Reply to Kobayashi T, Aida K, Fukui T et al [letter] and Saisho Y [letter].

Diabetologia 2016 Apr 9;59(4):870-2. Epub 2016 Feb 9.

Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, POB 100275, 1395 Center Drive, Gainesville, FL, 32610, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047275PMC
http://dx.doi.org/10.1007/s00125-016-3889-4DOI Listing
April 2016

Action or attention in social inhibition of return?

Psychol Res 2017 Jan 26;81(1):43-54. Epub 2015 Dec 26.

Department of Psychology, Centre for Brain Science, University of Essex, Colchester, CO4 3SQ, Essex, UK.

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http://dx.doi.org/10.1007/s00426-015-0738-xDOI Listing
January 2017

Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes.

Diabetes 2016 Mar 18;65(3):719-31. Epub 2015 Nov 18.

Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL Department of Pediatrics, University of Florida, Gainesville, FL.

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http://dx.doi.org/10.2337/db15-0779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764143PMC
March 2016

The influence of type 1 diabetes on pancreatic weight.

Diabetologia 2016 Jan 10;59(1):217-221. Epub 2015 Sep 10.

Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, POB 100275, 1395 Center Drive, Gainesville, FL, 32610, USA.

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http://link.springer.com/content/pdf/10.1007%2Fs00125-015-37
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http://link.springer.com/10.1007/s00125-015-3752-z
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http://dx.doi.org/10.1007/s00125-015-3752-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670792PMC
January 2016

A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice.

Sci Rep 2015 Aug 17;5:13155. Epub 2015 Aug 17.

J. Crayton Pruitt Family Department of Biomedical Engineering, College of Engineering, University of Florida, Gainesville, FL 32611, USA.

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http://dx.doi.org/10.1038/srep13155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538389PMC
August 2015

The role for gut permeability in the pathogenesis of type 1 diabetes--a solid or leaky concept?

Pediatr Diabetes 2015 Nov 13;16(7):485-92. Epub 2015 Aug 13.

Departments of Pathology, Immunology, and Laboratory Medicine, and Pediatrics, College of Medicine, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1111/pedi.12305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638168PMC
November 2015

Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes.

Diabetes 2015 Nov 16;64(11):3873-84. Epub 2015 Jul 16.

Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL

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http://dx.doi.org/10.2337/db15-0164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613966PMC
November 2015

A run on the biobank: what have we learned about type 1 diabetes from the nPOD tissue repository?

Curr Opin Endocrinol Diabetes Obes 2015 Aug;22(4):290-5

aDepartment of Information Sciences, City of Hope, Duarte, California bDiabetes Research Institute and Departments of Medicine, Microbiology and Immunology, University of Miami Miller School of Medicine, Miami cDepartments of Pathology and Pediatrics, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1097/MED.0000000000000171DOI Listing
August 2015