Publications by authors named "Marjorie Romkes"

59Publications

PARP1 rs1805407 Increases Sensitivity to PARP1 Inhibitors in Cancer Cells Suggesting an Improved Therapeutic Strategy.

Sci Rep 2019 03 1;9(1):3309. Epub 2019 Mar 1.

Department of Melanoma Medical Oncology, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1038/s41598-019-39542-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397203PMC
March 2019

Expression of PAM50 Genes in Lung Cancer: Evidence that Interactions between Hormone Receptors and HER2/HER3 Contribute to Poor Outcome.

Neoplasia 2015 Nov;17(11):817-25

Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15213; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15213. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2015.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681883PMC
November 2015

Lung Cancer Risk Prediction Using Common SNPs Located in GWAS-Identified Susceptibility Regions.

J Thorac Oncol 2015 Nov;10(11):1538-45

Departments of *Epidemiology and †Biostatistics, Graduate School of Public Health, Pittsburgh, Pennsylvania; Departments of ‡Medicine, §Radiology, and ‖Cardiothoracic Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; and ¶Department of Pharmacology, School of Medicine, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1097/JTO.0000000000000666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636453PMC
November 2015

15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers.

J Natl Cancer Inst 2015 Feb 23;107(5). Epub 2015 Feb 23.

: Lung Cancer Program, Lovelace Respiratory Research Institute, Albuquerque, NM (SL, YL, CLT, MAP, RPW, KCD, XZ, EAB, YT, SAB); Department of Epidemiology, Graduate School of Public Health (JLW) and Department of Medicine (TN, MR), University of Pittsburgh, Pittsburgh, PA; Center for Genomic Medicine, Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH (YH, CIA); Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA (CKE, DVDB, WJG, FDG); Department of Pharmacology & Chemical Biology, Hillman Cancer Center of the University of Pittsburgh Medical Center, Pittsburgh, PA (ALGD, JMS); Department of Internal Medicine, University of New Mexico, Albuquerque, NM (REC, CAS); Department of Pharmacology, University of Minnesota, Minneapolis, MN (JMS).

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http://jnci.oxfordjournals.org/content/107/5/djv035.full.pdf
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http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/djv035
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http://dx.doi.org/10.1093/jnci/djv035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555640PMC
February 2015

Identification of epidermal growth factor receptor (EGFR) genetic variants that modify risk for head and neck squamous cell carcinoma.

Cancer Lett 2015 Feb 12;357(2):549-56. Epub 2014 Dec 12.

Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295492PMC
February 2015

Inherited variation in the ATP-binding cassette transporter ABCB1 and survival after chemotherapy for stage III-IV lung cancer.

J Thorac Oncol 2014 Sep;9(9):1264-71

*University of Pittsburgh Cancer Institute and †Department of Epidemiology, University of Pittsburgh Graduate School of Public Health; ‡Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh School of Medicine; §Department of Medicine, University of Pittsburgh School of Medicine; ‖Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine; ¶Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864153067
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http://dx.doi.org/10.1097/JTO.0000000000000262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134100PMC
September 2014

Genotyping technologies: application to biotransformation enzyme genetic polymorphism screening.

Methods Mol Biol 2014 ;1105:99-115

Division of Hematology/Oncology, Department of Medicine, Hillman Cancer Center, 5117 Centre Avenue, Suite 1.32e, Pittsburgh, PA, 15213, USA,

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http://dx.doi.org/10.1007/978-1-62703-739-6_8DOI Listing
November 2014

Strategies for measurement of biotransformation enzyme gene expression.

Methods Mol Biol 2014 ;1105:85-97

Division of Hematology/Oncology, Department of Medicine, Hillman Cancer Center, 5117 Centre Avenue, Suite 1.32e, Pittsburgh, PA, 15213, USA,

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http://dx.doi.org/10.1007/978-1-62703-739-6_7DOI Listing
November 2014

An empirical workflow for genome-wide single nucleotide polymorphism-based predictive modeling.

AMIA Jt Summits Transl Sci Proc 2013 18;2013:53-7. Epub 2013 Mar 18.

Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814469PMC
December 2013

Childhood passive smoke exposure is associated with adult head and neck cancer.

Cancer Epidemiol 2013 Aug 22;37(4):417-23. Epub 2013 Apr 22.

Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1016/j.canep.2013.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706460PMC
August 2013

Genetic variation in ESR2 and estrogen receptor-beta expression in lung tumors.

Cancer Epidemiol 2013 Aug 23;37(4):518-22. Epub 2013 Apr 23.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.canep.2013.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684046PMC
August 2013

CYP2A6 genotype and smoking behavior in current smokers screened for lung cancer.

Subst Use Misuse 2013 May 25;48(7):490-4. Epub 2013 Mar 25.

Department of Health and Community Systems, University of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.3109/10826084.2013.778280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788637PMC
May 2013

Polymorphisms in NAT2 and GSTP1 are associated with survival in oral and oropharyngeal cancer.

Cancer Epidemiol 2013 Aug 21;37(4):505-11. Epub 2013 Mar 21.

Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1016/j.canep.2013.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690299PMC
August 2013

Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer.

Mol Carcinog 2012 Oct 4;51 Suppl 1:E11-20. Epub 2011 Oct 4.

Center for Clinical Pharmacology, University of Pittsburgh School of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1002/mc.20858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289753PMC
October 2012

XPF expression correlates with clinical outcome in squamous cell carcinoma of the head and neck.

Clin Cancer Res 2011 Aug 7;17(16):5513-22. Epub 2011 Jul 7.

Departments of Otolaryngology and Head and Neck Surgery, University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, PA 15213, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-0086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156890PMC
August 2011

A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.

Authors:
James D McKay Therese Truong Valerie Gaborieau Amelie Chabrier Shu-Chun Chuang Graham Byrnes David Zaridze Oxana Shangina Neonila Szeszenia-Dabrowska Jolanta Lissowska Peter Rudnai Eleonora Fabianova Alexandru Bucur Vladimir Bencko Ivana Holcatova Vladimir Janout Lenka Foretova Pagona Lagiou Dimitrios Trichopoulos Simone Benhamou Christine Bouchardy Wolfgang Ahrens Franco Merletti Lorenzo Richiardi Renato Talamini Luigi Barzan Kristina Kjaerheim Gary J Macfarlane Tatiana V Macfarlane Lorenzo Simonato Cristina Canova Antonio Agudo Xavier Castellsagué Ray Lowry David I Conway Patricia A McKinney Claire M Healy Mary E Toner Ariana Znaor Maria Paula Curado Sergio Koifman Ana Menezes Victor Wünsch-Filho José Eluf Neto Leticia Fernández Garrote Stefania Boccia Gabriella Cadoni Dario Arzani Andrew F Olshan Mark C Weissler William K Funkhouser Jingchun Luo Jan Lubiński Joanna Trubicka Marcin Lener Dorota Oszutowska Stephen M Schwartz Chu Chen Sherianne Fish David R Doody Joshua E Muscat Philip Lazarus Carla J Gallagher Shen-Chih Chang Zuo-Feng Zhang Qingyi Wei Erich M Sturgis Li-E Wang Silvia Franceschi Rolando Herrero Karl T Kelsey Michael D McClean Carmen J Marsit Heather H Nelson Marjorie Romkes Shama Buch Tomoko Nukui Shilong Zhong Martin Lacko Johannes J Manni Wilbert H M Peters Rayjean J Hung John McLaughlin Lars Vatten Inger Njølstad Gary E Goodman John K Field Triantafillos Liloglou Paolo Vineis Francoise Clavel-Chapelon Domenico Palli Rosario Tumino Vittorio Krogh Salvatore Panico Carlos A González J Ramón Quirós Carmen Martínez Carmen Navarro Eva Ardanaz Nerea Larrañaga Kay-Tee Khaw Timothy Key H Bas Bueno-de-Mesquita Petra H M Peeters Antonia Trichopoulou Jakob Linseisen Heiner Boeing Göran Hallmans Kim Overvad Anne Tjønneland Merethe Kumle Elio Riboli Kristjan Välk Tõnu Vooder Tõnu Voodern Andres Metspalu Diana Zelenika Anne Boland Marc Delepine Mario Foglio Doris Lechner Hélène Blanché Ivo G Gut Pilar Galan Simon Heath Mia Hashibe Richard B Hayes Paolo Boffetta Mark Lathrop Paul Brennan

PLoS Genet 2011 Mar 17;7(3):e1001333. Epub 2011 Mar 17.

International Agency for Research on Cancer (IARC), Lyon, France.

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http://pure.au.dk/ws/files/36381633/A_Genome_Wide_Associatio
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http://dx.plos.org/10.1371/journal.pgen.1001333
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http://dx.doi.org/10.1371/journal.pgen.1001333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060072PMC
March 2011

A sex-specific association between a 15q25 variant and upper aerodigestive tract cancers.

Cancer Epidemiol Biomarkers Prev 2011 Apr 18;20(4):658-64. Epub 2011 Feb 18.

International Agency for Research on Cancer (IARC), 150 Cours Albert Thomas, 69372 Lyon CEDEX 08, France.

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http://dx.doi.org/10.1158/1055-9965.EPI-10-1008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070066PMC
April 2011

Genetic polymorphisms in the DNA repair genes XPD and XRCC1, p53 gene mutations and bladder cancer risk.

Oncol Rep 2010 Jul;24(1):257-62

The Institute of Environmental and Human Health (TIEHH) and Department of Environmental Toxicology, Texas Tech University, Lubbock, TX 79409, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638861PMC
http://dx.doi.org/10.3892/or_00000854DOI Listing
July 2010

Smoking behavior 1 year after computed tomography screening for lung cancer: Effect of physician referral for abnormal CT findings.

Cancer Epidemiol Biomarkers Prev 2009 Dec;18(12):3484-9

Department of Health and Community Systems, University of Pittsburgh School of Nursing, PA, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789354PMC
December 2009

Pharmacogenomics.

Methods Mol Biol 2009 ;520:231-45

Department of Medicine, Center for Clinical Pharmacology, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/978-1-60327-811-9_17DOI Listing
May 2009

Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes.

Head Neck 2008 Sep;30(9):1139-47

Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1002/hed.20867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627181PMC
September 2008

The impact of genetic variation in DRD2 and SLC6A3 on smoking cessation in a cohort of participants 1 year after enrollment in a lung cancer screening study.

Am J Med Genet B Neuropsychiatr Genet 2009 Mar;150B(2):254-61

Department of Health and Community Systems, University of Pittsburgh School of Nursing, Pennsylvania, USA.

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http://dx.doi.org/10.1002/ajmg.b.30801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730224PMC
March 2009

Mutation and polymorphism in the EGFR-TK domain associated with lung cancer.

J Thorac Oncol 2006 Sep;1(7):635-47

Department of Pharmacology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213-1863, USA.

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September 2006

Association of the EGFR intron 1 CA repeat length with lung cancer risk.

Mol Carcinog 2007 May;46(5):372-80

Department of Pharmacology, University of Pittsburgh Cancer Institute, SPORE in Lung Cancer, University of Pittsburgh, Pittsburgh, Pennsylvania 15213-1863, USA.

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http://dx.doi.org/10.1002/mc.20285DOI Listing
May 2007

Validation of incorporating flurbiprofen into the Pittsburgh cocktail.

Clin Pharmacol Ther 2006 Sep;80(3):257-63

Center for Clinical Pharmacology, University of Pittsburgh, Pittsburgh, PA 15219-3138, USA.

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http://dx.doi.org/10.1016/j.clpt.2006.06.005DOI Listing
September 2006

Polymorphisms in DNA repair genes XPD and XRCC1 and p53 mutations in lung carcinomas of never-smokers.

Mol Carcinog 2006 Nov;45(11):828-32

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15219, USA.

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http://dx.doi.org/10.1002/mc.20208DOI Listing
November 2006

CYP2D6 genotype and venlafaxine-XR concentrations in depressed elderly.

Int J Geriatr Psychiatry 2006 Jun;21(6):542-9

Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, USA.

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http://dx.doi.org/10.1002/gps.1522DOI Listing
June 2006

The absence of interaction between drug metabolizing enzyme genotypes and maternal lifestyle factors on glycophorin A somatic mutation frequency levels in newborns.

Pharmacogenet Genomics 2006 Feb;16(2):129-38

Center for Clinical Pharmacology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15219, USA.

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http://dx.doi.org/10.1097/01.fpc.0000184954.08453.e1DOI Listing
February 2006

Association of polymorphisms in the cyclin D1 and XPD genes and susceptibility to cancers of the upper aero-digestive tract.

Mol Carcinog 2005 Apr;42(4):222-8

Center for Clinical Pharmacology, Department of Medicine, University of Pittsburgh, 100 Technology Drive, Pittsburgh, PA 15219, USA.

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http://dx.doi.org/10.1002/mc.20086DOI Listing
April 2005

Bioequivalence revisited: influence of age and sex on CYP enzymes.

Clin Pharmacol Ther 2004 Dec;76(6):618-27

Center for Clinical Pharmacology and Department of Pharmaceutical Sciences, University of Pittsburgh, PA 15219, USA.

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http://dx.doi.org/10.1016/j.clpt.2004.08.021DOI Listing
December 2004

Genotyping technologies: application to biotransformation enzyme genetic polymorphism screening.

Methods Mol Biol 2005 ;291:399-414

Center for Clinical Pharmacology, University of Pittsburgh, PA, USA.

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http://dx.doi.org/10.1385/1-59259-840-4:399DOI Listing
February 2005

Strategies for measurement of biotransformation enzyme gene expression.

Methods Mol Biol 2005 ;291:387-98

Center for Clinical Pharmacology, University of Pittsburgh, PA, USA.

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http://dx.doi.org/10.1385/1-59259-840-4:387DOI Listing
February 2005

Maternal/newborn GSTT1 null genotype contributes to risk of preterm, low birthweight infants.

Pharmacogenetics 2004 Sep;14(9):569-76

Department of Medicine, The Center of Clinical Pharmacology, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/00008571-200409000-00001DOI Listing
September 2004

No association between the XPD 312, 751, or XRCC1 399 polymorphisms and K-ras gene mutation in smoking non-small-cell lung cancer.

Cancer Epidemiol Biomarkers Prev 2004 Apr;13(4):673-5

Department of Environmental and Occupational Health, University of Pittsburgh, 3343 Forbes Avenue, Pittsburgh, PA 15260, USA.

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April 2004

A potential role for the estrogen-metabolizing cytochrome P450 enzymes in human breast carcinogenesis.

Breast Cancer Res Treat 2003 Dec;82(3):191-7

Department of Epidemiology, University of Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1023/B:BREA.0000004376.21491.44DOI Listing
December 2003

Association of the DNA repair gene XPD Asp312Asn polymorphism with p53 gene mutations in tobacco-related non-small cell lung cancer.

Carcinogenesis 2003 Oct 4;24(10):1671-6. Epub 2003 Jul 4.

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1093/carcin/bgg115DOI Listing
October 2003