Marja-Riitta Taskinen

Marja-Riitta Taskinen

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Marja-Riitta Taskinen

Marja-Riitta Taskinen

Publications by authors named "Marja-Riitta Taskinen"

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Relationship between alirocumab, PCSK9, and LDL-C levels in four phase 3 ODYSSEY trials using 75 and 150 mg doses.

Authors:
Jennifer G Robinson Michel Farnier John J P Kastelein Eli M Roth Marja-Riitta Taskinen Helen M Colhoun Aurelie Brunet A Thomas DiCioccio Guillaume Lecorps Robert Pordy Marie T Baccara-Dinet Christopher P Cannon

J Clin Lipidol 2019 Oct 14. Epub 2019 Oct 14.

Harvard Clinical Research Institute, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jacl.2019.10.004DOI Listing
October 2019

A higher glycemic response to oral glucose is associated with higher plasma apolipoprotein C3 independently of BMI in healthy twins.

Authors:
Lutgarda Bozzetto Bram J Berntzen Jaakko Kaprio Aila Rissanen Marja-Riitta Taskinen Kirsi H Pietiläinen

Nutr Metab Cardiovasc Dis 2019 Oct 15. Epub 2019 Oct 15.

Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Obesity Center, Endocrinology, Abdominal Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.numecd.2019.10.005DOI Listing
October 2019

Genetic architecture of human plasma lipidome and its link to cardiovascular disease.

Authors:
Rubina Tabassum Joel T Rämö Pietari Ripatti Jukka T Koskela Mitja Kurki Juha Karjalainen Priit Palta Shabbeer Hassan Javier Nunez-Fontarnau Tuomo T J Kiiskinen Sanni Söderlund Niina Matikainen Mathias J Gerl Michal A Surma Christian Klose Nathan O Stitziel Hannele Laivuori Aki S Havulinna Susan K Service Veikko Salomaa Matti Pirinen Matti Jauhiainen Mark J Daly Nelson B Freimer Aarno Palotie Marja-Riitta Taskinen Kai Simons Samuli Ripatti

Nat Commun 2019 Sep 24;10(1):4329. Epub 2019 Sep 24.

Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/s41467-019-11954-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760179PMC
September 2019

Role of apolipoprotein C-III overproduction in diabetic dyslipidaemia.

Authors:
Martin Adiels Marja-Riitta Taskinen Elias Björnson Linda Andersson Niina Matikainen Sanni Söderlund Juhani Kahri Antti Hakkarainen Nina Lundbom Carina Sihlbom Annika Thorsell Haihong Zhou Kirsi H Pietiläinen Chris Packard Jan Borén

Diabetes Obes Metab 2019 Aug 8;21(8):1861-1870. Epub 2019 May 8.

Department of Molecular and Clinical Medicine, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/dom.13744DOI Listing
August 2019

Dietary Fructose and the Metabolic Syndrome.

Authors:
Marja-Riitta Taskinen Chris J Packard Jan Borén

Nutrients 2019 Aug 22;11(9). Epub 2019 Aug 22.

Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.

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http://dx.doi.org/10.3390/nu11091987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770027PMC
August 2019

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk.

Authors:
François Mach Colin Baigent Alberico L Catapano Konstantinos C Koskinas Manuela Casula Lina Badimon M John Chapman Guy G De Backer Victoria Delgado Brian A Ference Ian M Graham Alison Halliday Ulf Landmesser Borislava Mihaylova Terje R Pedersen Gabriele Riccardi Dimitrios J Richter Marc S Sabatine Marja-Riitta Taskinen Lale Tokgozoglu Olov Wiklund

Eur Heart J 2019 Aug 31. Epub 2019 Aug 31.

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http://dx.doi.org/10.1093/eurheartj/ehz455DOI Listing
August 2019

Coronary Artery Disease Risk and Lipidomic Profiles Are Similar in Hyperlipidemias With Family History and Population-Ascertained Hyperlipidemias.

Authors:
Joel T Rämö Pietari Ripatti Rubina Tabassum Sanni Söderlund Niina Matikainen Mathias J Gerl Christian Klose Michal A Surma Nathan O Stitziel Aki S Havulinna Matti Pirinen Veikko Salomaa Nelson B Freimer Matti Jauhiainen Aarno Palotie Marja-Riitta Taskinen Kai Simons Samuli Ripatti

J Am Heart Assoc 2019 Jul 29;8(13):e012415. Epub 2019 Jun 29.

1 Institute for Molecular Medicine Finland HiLIFE University of Helsinki Finland.

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http://dx.doi.org/10.1161/JAHA.119.012415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662358PMC
July 2019

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation.

Authors:
Jean-Charles Fruchart Raul D Santos Carlos Aguilar-Salinas Masanori Aikawa Khalid Al Rasadi Pierre Amarenco Philip J Barter Richard Ceska Alberto Corsini Jean-Pierre Després Patrick Duriez Robert H Eckel Marat V Ezhov Michel Farnier Henry N Ginsberg Michel P Hermans Shun Ishibashi Fredrik Karpe Tatsuhiko Kodama Wolfgang Koenig Michel Krempf Soo Lim Alberto J Lorenzatti Ruth McPherson Jesus Millan Nuñez-Cortes Børge G Nordestgaard Hisao Ogawa Chris J Packard Jorge Plutzky Carlos I Ponte-Negretti Aruna Pradhan Kausik K Ray Željko Reiner Paul M Ridker Massimiliano Ruscica Shaukat Sadikot Hitoshi Shimano Piyamitr Sritara Jane K Stock Ta-Chen Su Andrey V Susekov André Tartar Marja-Riitta Taskinen Alexander Tenenbaum Lale S Tokgözoğlu Brian Tomlinson Anne Tybjærg-Hansen Paul Valensi Michal Vrablík Walter Wahli Gerald F Watts Shizuya Yamashita Koutaro Yokote Alberto Zambon Peter Libby

Cardiovasc Diabetol 2019 06 4;18(1):71. Epub 2019 Jun 4.

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1186/s12933-019-0864-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549355PMC
June 2019

Emerging Evidence that ApoC-III Inhibitors Provide Novel Options to Reduce the Residual CVD.

Authors:
Marja-Riitta Taskinen Chris J Packard Jan Borén

Curr Atheroscler Rep 2019 May 20;21(8):27. Epub 2019 May 20.

Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s11883-019-0791-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527792PMC
May 2019

Crosstalk between nonalcoholic fatty liver disease and cardiometabolic syndrome.

Authors:
Soo Lim Marja-Riitta Taskinen Jan Borén

Obes Rev 2019 04 27;20(4):599-611. Epub 2018 Dec 27.

Department of Molecular and Clinical Medicine/Wallenberg Lab, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://doi.wiley.com/10.1111/obr.12820
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http://dx.doi.org/10.1111/obr.12820DOI Listing
April 2019

Liraglutide treatment improves postprandial lipid metabolism and cardiometabolic risk factors in humans with adequately controlled type 2 diabetes: A single-centre randomized controlled study.

Authors:
Niina Matikainen Sanni Söderlund Elias Björnson Kirsi Pietiläinen Antti Hakkarainen Nina Lundbom Marja-Riitta Taskinen Jan Borén

Diabetes Obes Metab 2019 01 4;21(1):84-94. Epub 2018 Sep 4.

Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/dom.13487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585708PMC
January 2019

USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages.

Authors:
Maija Ruuth Jarkko Soronen Essi Kaiharju Krista Merikanto Julia Perttilä Jari Metso Miriam Lee-Rueckert Marja-Riitta Taskinen Petri T Kovanen Katariina Öörni Vesa M Olkkonen Matti S Jauhiainen Pirkka-Pekka Laurila

Lipids Health Dis 2018 Dec 13;17(1):285. Epub 2018 Dec 13.

Genomics and Biomarkers Unit, National Institute for Health and Welfare, FI-00251, Helsinki, Finland.

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https://lipidworld.biomedcentral.com/articles/10.1186/s12944
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http://dx.doi.org/10.1186/s12944-018-0930-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293625PMC
December 2018

Efficacy and safety of alirocumab in individuals with type 2 diabetes mellitus with or without mixed dyslipidaemia: Analysis of the ODYSSEY LONG TERM trial.

Authors:
Marja-Riitta Taskinen Stefano Del Prato Maja Bujas-Bobanovic Michael J Louie Alexia Letierce Desmond Thompson Helen M Colhoun

Atherosclerosis 2018 09 21;276:124-130. Epub 2018 Jul 21.

University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.07.017DOI Listing
September 2018

Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome.

Authors:
Alen Lovric Marit Granér Elias Bjornson Muhammad Arif Rui Benfeitas Kristofer Nyman Marcus Ståhlman Markku O Pentikäinen Jesper Lundbom Antti Hakkarainen Reijo Sirén Markku S Nieminen Nina Lundbom Kirsi Lauerma Marja-Riitta Taskinen Adil Mardinoglu Jan Boren

Sci Rep 2018 09 21;8(1):14200. Epub 2018 Sep 21.

Department of Molecular and Clinical Medicine/Wallenberg Lab, University of Gothenburg, and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1038/s41598-018-31865-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155005PMC
September 2018

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.

Authors:
Adil Mardinoglu Hao Wu Elias Bjornson Cheng Zhang Antti Hakkarainen Sari M Räsänen Sunjae Lee Rosellina M Mancina Mattias Bergentall Kirsi H Pietiläinen Sanni Söderlund Niina Matikainen Marcus Ståhlman Per-Olof Bergh Martin Adiels Brian D Piening Marit Granér Nina Lundbom Kevin J Williams Stefano Romeo Jens Nielsen Michael Snyder Mathias Uhlén Göran Bergström Rosie Perkins Hanns-Ulrich Marschall Fredrik Bäckhed Marja-Riitta Taskinen Jan Borén

Cell Metab 2018 03 15;27(3):559-571.e5. Epub 2018 Feb 15.

Department of Molecular and Clinical Medicine, University of Gothenburg, and Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706084PMC
March 2018

Family-specific aggregation of lipid GWAS variants confers the susceptibility to familial hypercholesterolemia in a large Austrian family.

Authors:
Elina Nikkola Arthur Ko Marcus Alvarez Rita M Cantor Kristina Garske Elliot Kim Stephanie Gee Alejandra Rodriguez Reinhard Muxel Niina Matikainen Sanni Söderlund Mahdi M Motazacker Jan Borén Claudia Lamina Florian Kronenberg Wolfgang J Schneider Aarno Palotie Markku Laakso Marja-Riitta Taskinen Päivi Pajukanta

Atherosclerosis 2017 Sep 22;264:58-66. Epub 2017 Jul 22.

Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, USA; Molecular Biology Institute at UCLA, Los Angeles, USA; Bioinformatics Interdepartmental Program, UCLA, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.07.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698088PMC
September 2017

Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel.

Authors:
Brian A Ference Henry N Ginsberg Ian Graham Kausik K Ray Chris J Packard Eric Bruckert Robert A Hegele Ronald M Krauss Frederick J Raal Heribert Schunkert Gerald F Watts Jan Borén Sergio Fazio Jay D Horton Luis Masana Stephen J Nicholls Børge G Nordestgaard Bart van de Sluis Marja-Riitta Taskinen Lale Tokgözoglu Ulf Landmesser Ulrich Laufs Olov Wiklund Jane K Stock M John Chapman Alberico L Catapano

Eur Heart J 2017 Aug;38(32):2459-2472

Department of Pharmacological and Biomolecular Sciences, University of Milan and IRCCS Multimedica, Milan, Italy.

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http://dx.doi.org/10.1093/eurheartj/ehx144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837225PMC
August 2017

Baseline Circulating FGF21 Concentrations and Increase after Fenofibrate Treatment Predict More Rapid Glycemic Progression in Type 2 Diabetes: Results from the FIELD Study.

Authors:
Kwok-Leung Ong Rachel O'Connell Andrzej S Januszewski Alicia J Jenkins Aimin Xu David R Sullivan Philip J Barter Russell S Scott Marja-Riitta Taskinen Boris Waldman Peter G Colman James D Best John R Simes Kerry-Anne Rye Anthony C Keech

Clin Chem 2017 Jul 12;63(7):1261-1270. Epub 2017 Jun 12.

Lipid Research Group, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.

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http://www.clinchem.org/lookup/doi/10.1373/clinchem.2016.270
Publisher Site
http://dx.doi.org/10.1373/clinchem.2016.270876DOI Listing
July 2017

Personal model-assisted identification of NAD and glutathione metabolism as intervention target in NAFLD.

Authors:
Adil Mardinoglu Elias Bjornson Cheng Zhang Martina Klevstig Sanni Söderlund Marcus Ståhlman Martin Adiels Antti Hakkarainen Nina Lundbom Murat Kilicarslan Björn M Hallström Jesper Lundbom Bruno Vergès Peter Hugh R Barrett Gerald F Watts Mireille J Serlie Jens Nielsen Mathias Uhlén Ulf Smith Hanns-Ulrich Marschall Marja-Riitta Taskinen Jan Boren

Mol Syst Biol 2017 03 2;13(3):916. Epub 2017 Mar 2.

Department of Molecular and Clinical Medicine, University of Gothenburg, and Sahlgrenska University Hospital, Gothenburg, Sweden

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371732PMC
http://dx.doi.org/10.15252/msb.20167422DOI Listing
March 2017

Kinetics of plasma triglycerides in abdominal obesity.

Authors:
Elias Björnson Martin Adiels Marja-Riitta Taskinen Jan Borén

Curr Opin Lipidol 2017 02;28(1):11-18

aDepartment of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden bResearch Programs Unit, Diabetes and Obesity, University of Helsinki and Heart and Lung Center, Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1097/MOL.0000000000000375DOI Listing
February 2017

Why Is Apolipoprotein CIII Emerging as a Novel Therapeutic Target to Reduce the Burden of Cardiovascular Disease?

Authors:
Marja-Riitta Taskinen Jan Borén

Curr Atheroscler Rep 2016 10;18(10):59

Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s11883-016-0614-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018018PMC
October 2016

Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men.

Authors:
Niina Matikainen Elias Björnson Sanni Söderlund Christofer Borén Björn Eliasson Kirsi H Pietiläinen Leonie H Bogl Antti Hakkarainen Nina Lundbom Angela Rivellese Gabriele Riccardi Jean-Pierre Després Natalie Alméras Jens Juul Holst Carolyn F Deacon Jan Borén Marja-Riitta Taskinen

PLoS One 2016 11;11(1):e0145890. Epub 2016 Jan 11.

Research programs Unit, Diabetes and Obesity, University of Helsinki and Heart and Lung Center, Helsinki University Hospital, Helsinki, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145890PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709062PMC
June 2016

Improved Estimation of Human Lipoprotein Kinetics with Mixed Effects Models.

Authors:
Martin Berglund Martin Adiels Marja-Riitta Taskinen Jan Borén Bernt Wennberg

PLoS One 2015 30;10(9):e0138538. Epub 2015 Sep 30.

Department of Mathematical Sciences, Chalmers University of Technology and the University of Gothenburg, Göteborg, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138538PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589417PMC
May 2016

The Contribution of GWAS Loci in Familial Dyslipidemias.

Authors:
Pietari Ripatti Joel T Rämö Sanni Söderlund Ida Surakka Niina Matikainen Matti Pirinen Päivi Pajukanta Antti-Pekka Sarin Susan K Service Pirkka-Pekka Laurila Christian Ehnholm Veikko Salomaa Richard K Wilson Aarno Palotie Nelson B Freimer Marja-Riitta Taskinen Samuli Ripatti

PLoS Genet 2016 05 26;12(5):e1006078. Epub 2016 May 26.

Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1371/journal.pgen.1006078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882070PMC
May 2016

ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal Obesity.

Authors:
Bruno Vergès Martin Adiels Jan Boren Peter Hugh Barrett Gerald F Watts Dick Chan Laurence Duvillard Sanni Söderlund Niina Matikainen Juhani Kahri Nina Lundbom Jesper Lundbom Antti Hakkarainen Serge Aho Isabelle Simoneau-Robin Marja-Riitta Taskinen

J Clin Endocrinol Metab 2016 Apr 2;101(4):1398-406. Epub 2016 Feb 2.

Departments of Endocrinology-Diabetology (B.V., I.S.-R.), Medical Biology (L.D.), and Statistics and Epidemiology (S.A.), University Hospital, 21000 Dijon, France; Centre Recherche INSERM 866 (B.V., L.D.), 21079 Dijon, France; Departments of Molecular and Clinical Medicine (M.A., J.B.) and Mathematical Sciences (M.A.), University of Gothenburg, S-405 30 Gothenburg, Sweden; Faculty of Engineering, Computing, and Mathematics (P.H.B.), University of Western Australia, Perth, Western Australia 6872, Australia; Lipid Disorders Clinic (G.F.W., D.C.), Metabolic Research Centre, Department of Cardiovascular Medicine, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia 6847, Australia; and Heart and Lung Centre (S.S., N.M., M.-R.T.), Helsinki University Hospital and Research Programs' Unit, Department of Diabetes and Obesity, University of Helsinki, Endocrinology, Abdominal Centre (N.M.), Department of Internal Medicine and Rehabilitation (J.K.), and Department of Radiology (N.L., J.L., A.H.), Helsingin ja Uudenmaan Sairaanhoitopiiri Medical Imaging Centre, Helsinki University Hospital, FI-00290 Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2015-3740DOI Listing
April 2016

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Authors:
Pirkka-Pekka Laurila Jarkko Soronen Sander Kooijman Saara Forsström Mariëtte R Boon Ida Surakka Essi Kaiharju Claudia P Coomans Sjoerd A A Van Den Berg Anu Autio Antti-Pekka Sarin Johannes Kettunen Emmi Tikkanen Tuula Manninen Jari Metso Reija Silvennoinen Krista Merikanto Maija Ruuth Julia Perttilä Anne Mäkelä Ayaka Isomi Anita M Tuomainen Anna Tikka Usama Abo Ramadan Ilkka Seppälä Terho Lehtimäki Johan Eriksson Aki Havulinna Antti Jula Pekka J Karhunen Veikko Salomaa Markus Perola Christian Ehnholm Miriam Lee-Rueckert Miranda Van Eck Anne Roivainen Marja-Riitta Taskinen Leena Peltonen Eero Mervaala Anu Jalanko Esa Hohtola Vesa M Olkkonen Samuli Ripatti Petri T Kovanen Patrick C N Rensen Anu Suomalainen Matti Jauhiainen

Sci Transl Med 2016 Jan;8(323):323ra13

Genomics and Biomarkers Unit, National Institute for Health and Welfare, Helsinki FI-00251, Finland.

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http://dx.doi.org/10.1126/scitranslmed.aad0015DOI Listing
January 2016

Kinetic Studies to Elucidate Impaired Metabolism of Triglyceride-rich Lipoproteins in Humans.

Authors:
Martin Adiels Adil Mardinoglu Marja-Riitta Taskinen Jan Borén

Front Physiol 2015 20;6:342. Epub 2015 Nov 20.

Department of Molecular and Clinical Medicine/Wallenberg Laboratory, University of Gothenburg Gothenburg, Sweden.

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http://dx.doi.org/10.3389/fphys.2015.00342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653309PMC
December 2015

Kinetic and Related Determinants of Plasma Triglyceride Concentration in Abdominal Obesity: Multicenter Tracer Kinetic Study.

Authors:
Jan Borén Gerald F Watts Martin Adiels Sanni Söderlund Dick C Chan Antti Hakkarainen Nina Lundbom Niina Matikainen Juhani Kahri Bruno Vergès P Hugh R Barrett Marja-Riitta Taskinen

Arterioscler Thromb Vasc Biol 2015 Oct 27;35(10):2218-24. Epub 2015 Aug 27.

From the Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden (J.B., M.A.); Lipid Disorders Clinic, Metabolic Research Centre, Cardiovascular Medicine, Royal Perth Hospital, School of Medicine and Pharmacology (G.F.W., D.C.C., P.H.R.B.) and Faculty of Engineering, Computing and Mathematics (P.H.R.B.), University of Western Australia, Perth, Australia; Heart and Lung Centre, Helsinki University Central Hospital and Research Programs' Unit, Diabetes and Obesity (S.S., N.M., M.-R.T.) and Department of Radiology, HUS Medical Imaging Center, Helsinki University Central Hospital (A.H., N.L.), University of Helsinki, Helsinki, Finland; Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland (N.M., J.K.); and Department of Endocrinology-Diabetology, University Hospital and INSERM CRI 866, Dijon, France (B.V.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305614DOI Listing
October 2015

Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment.

Authors:
Albert Wiegman Samuel S Gidding Gerald F Watts M John Chapman Henry N Ginsberg Marina Cuchel Leiv Ose Maurizio Averna Catherine Boileau Jan Borén Eric Bruckert Alberico L Catapano Joep C Defesche Olivier S Descamps Robert A Hegele G Kees Hovingh Steve E Humphries Petri T Kovanen Jan Albert Kuivenhoven Luis Masana Børge G Nordestgaard Päivi Pajukanta Klaus G Parhofer Frederick J Raal Kausik K Ray Raul D Santos Anton F H Stalenhoef Elisabeth Steinhagen-Thiessen Erik S Stroes Marja-Riitta Taskinen Anne Tybjærg-Hansen Olov Wiklund

Eur Heart J 2015 Sep 25;36(36):2425-37. Epub 2015 May 25.

Department of Experimental and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1093/eurheartj/ehv157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576143PMC
September 2015

Relationship of fibroblast growth factor 21 with baseline and new on-study microvascular disease in the Fenofibrate Intervention and Event Lowering in Diabetes study.

Authors:
Kwok-Leung Ong Andrzej S Januszewski Rachel O'Connell Luke Buizen Alicia J Jenkins Aimin Xu David R Sullivan Philip J Barter Russell S Scott Marja-Riitta Taskinen Kerry-Anne Rye Anthony C Keech

Diabetologia 2015 Sep 9;58(9):2035-44. Epub 2015 Jun 9.

Centre for Vascular Research, University of New South Wales, Sydney, NSW, 2052, Australia,

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http://dx.doi.org/10.1007/s00125-015-3652-2DOI Listing
September 2015

PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis.

Authors:
Sven Francque An Verrijken Sandrine Caron Janne Prawitt Réjane Paumelle Bruno Derudas Philippe Lefebvre Marja-Riitta Taskinen Wim Van Hul Ilse Mertens Guy Hubens Eric Van Marck Peter Michielsen Luc Van Gaal Bart Staels

J Hepatol 2015 Jul 19;63(1):164-73. Epub 2015 Feb 19.

Université Lille 2, INSERM U1011, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille, France.

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http://dx.doi.org/10.1016/j.jhep.2015.02.019DOI Listing
July 2015

Paradoxical dissociation between hepatic fat content and de novo lipogenesis due to PNPLA3 sequence variant.

Authors:
Rosellina M Mancina Niina Matikainen Cristina Maglio Sanni Söderlund Nina Lundbom Antti Hakkarainen Raffaela Rametta Enrico Mozzi Silvia Fargion Luca Valenti Stefano Romeo Marja-Riitta Taskinen Jan Borén

J Clin Endocrinol Metab 2015 May 12;100(5):E821-5. Epub 2015 Mar 12.

Department of Molecular and Clinical Medicine (R.M.M, C.M, S.R., J.B.), University of Gothenburg, S-413 45 Gothenburg, Sweden; Department of Medicine, Cardiovascular Research Unit, Diabetes and Obesity Research Program (N.M., S.S., M.-R.T.), Heart and Lung Centre and Division of Endocrinology and Helsinki University Central Hospital, University of Helsinki, 00100 Helsinki, Finland; Department of Radiology, HUS Medical Imaging Center (N.L., A.H.), Helsinki University Central Hospital, University of Helsinki, 00100 Helsinki, Finland; Departments of Internal Medicine (R.R, S.F., L.V.), and General Surgery (E.M.), Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Policlinico, and Department of Pathophysiology and Transplantation Università degli Studi di Milano, 20122 Milano, Italy; and Department of Medical and Surgical Sciences (S.R.), Clinical Nutrition Unit, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.

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http://dx.doi.org/10.1210/jc.2014-4464DOI Listing
May 2015

High-fat meals induce systemic cytokine release without evidence of endotoxemia-mediated cytokine production from circulating monocytes or myeloid dendritic cells.

Authors:
Christopher L Fogarty Janne K Nieminen Lina Peräneva Mariann I Lassenius Aila J Ahola Marja-Riitta Taskinen Matti Jauhiainen Juha Kirveskari Pirkko Pussinen Sohvi Hörkkö Ville-Petteri Mäkinen Daniel Gordin Carol Forsblom Per-Henrik Groop Outi Vaarala Markku Lehto

Acta Diabetol 2015 Apr 3;52(2):315-22. Epub 2014 Sep 3.

Folkhälsan Research Center, Biomedicum Helsinki (Room C317b), Haartmaninkatu 8, 00290, Helsinki, Finland.

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http://link.springer.com/content/pdf/10.1007/s00592-014-0641
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http://link.springer.com/10.1007/s00592-014-0641-8
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http://dx.doi.org/10.1007/s00592-014-0641-8DOI Listing
April 2015

New insights into the pathophysiology of dyslipidemia in type 2 diabetes.

Authors:
Marja-Riitta Taskinen Jan Borén

Atherosclerosis 2015 Apr 7;239(2):483-95. Epub 2015 Feb 7.

Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.01.039DOI Listing
April 2015

The relationship of fibroblast growth factor 21 with cardiovascular outcome events in the Fenofibrate Intervention and Event Lowering in Diabetes study.

Authors:
Kwok-Leung Ong Andrzej S Januszewski Rachel O'Connell Alicia J Jenkins Aimin Xu David R Sullivan Philip J Barter Wei-Ting Hung Russell S Scott Marja-Riitta Taskinen Anthony C Keech Kerry-Anne Rye

Diabetologia 2015 Mar 26;58(3):464-73. Epub 2014 Nov 26.

Lipid Research Group, Heart Research Institute, Sydney, NSW, Australia,

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http://dx.doi.org/10.1007/s00125-014-3458-7DOI Listing
March 2015

[Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society].

Authors:
Marina Cuchel Eric Bruckert Henry N Ginsberg Frederick J Raal Raul D Santos Robert A Hegele Jan Albert Kuivenhoven Børge G Nordestgaard Olivier S Descamps Elisabeth Steinhagen-Thiessen Anne Tybjaerg-Hansen Gerald F Watts Maurizio Averna Catherine Boileau Jan Borén Alberico L Catapano Joep C Defesche G Kees Hovingh Steve E Humphries Petri T Kovanen Luis Masana Päivi Pajukanta Klaus G Parhofer Kausik K Ray Anton F H Stalenhoef Erik Stroes Marja-Riitta Taskinen Albert Wiegman Olov Wiklund M John Chapman

Turk Kardiyol Dern Ars 2015 Mar;43 Suppl 1:1-14

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March 2015

Measuring short-term liver metabolism non-invasively: postprandial and post-exercise ¹H and ³¹P MR spectroscopy.

Authors:
Antti Hakkarainen Jesper Lundbom Esa K Tuominen Marja-Riitta Taskinen Kirsi H Pietiläinen Nina Lundbom

MAGMA 2015 Feb 4;28(1):57-66. Epub 2014 Jun 4.

Department of Radiology, HUS Medical Imaging Center, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland,

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http://dx.doi.org/10.1007/s10334-014-0450-7DOI Listing
February 2015

Ectopic fat depots and left ventricular function in nondiabetic men with nonalcoholic fatty liver disease.

Authors:
Marit Granér Kristofer Nyman Reijo Siren Markku O Pentikäinen Jesper Lundbom Antti Hakkarainen Kirsi Lauerma Nina Lundbom Markku S Nieminen Marja-Riitta Taskinen

Circ Cardiovasc Imaging 2015 Jan 30;8(1). Epub 2014 Dec 30.

From the Diabetes and Obesity Research Program, Division of Cardiology, Heart and Lung Center, Helsinki University Central Hospital (M.G., M.O.P., M.S.N., M.-R.T.), Department of Radiology, HUS Medical Imaging Center, Helsinki University Central Hospital (K.N., J.L., A.H., K.L., N.L.), and Department of General Practice and Primary Health Care, Health Center of City of Helsinki (R.S.), University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1161/CIRCIMAGING.114.001979DOI Listing
January 2015

Interrelationships between the kinetics of VLDL subspecies and HDL catabolism in abdominal obesity: a multicenter tracer kinetic study.

Authors:
Bruno Vergès Martin Adiels Jan Boren Peter Hugh Barrett Gerald F Watts Dick Chan Laurence Duvillard Sanni Söderlund Niina Matikainen Juhani Kahri Isabelle Robin Marja-Riitta Taskinen

J Clin Endocrinol Metab 2014 Nov 31;99(11):4281-90. Epub 2014 Jul 31.

Departments of Endocrinology-Diabetology (B.V., I.R.) and Medical Biology (L.D.), University Hospital, and INSERM CRI 866 (B.V., L.D.), 21000 Dijon, France; Departments of Molecular and Clinical Medicine (M.A., J.B.) and Mathematical Sciences (M.A.), University of Gothenburg, S-405 30 Gothenburg, Sweden; Faculty of Engineering, Computing, and Mathematics (H.B.), University of Western Australia, Perth, Western Australia 6872, Australia; Lipid Disorders Clinic (H.B., G.F.W., D.C.), Metabolic Research Centre, Department of Cardiovascular Medicine, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia 6847, Australia; and Heart and Lung Centre (S.S., N.M., M.-R.T.), Helsinki University Central Hospital and Research Programs' Unit, Department of Diabetes and Obesity, University of Helsinki, and Department of Medicine (N.M., J.K.), Helsinki University Central Hospital, 00290 Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2014-2365DOI Listing
November 2014

Factors associated with postprandial lipemia and apolipoprotein A-V levels in individuals with familial combined hyperlipidemia.

Authors:
Paloma Almeda-Valdes Daniel Cuevas-Ramos Roopa Mehta Liliana Muñoz-Hernandez Ivette Cruz-Bautista Oscar Perez-Mendez Maria Teresa Tusie-Luna Francisco J Gomez-Perez Päivi Pajukanta Niina Matikainen Marja-Riitta Taskinen Carlos A Aguilar-Salinas

BMC Endocr Disord 2014 Nov 25;14:90. Epub 2014 Nov 25.

Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico.

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http://dx.doi.org/10.1186/1472-6823-14-90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253986PMC
November 2014

Genetic variation in SULF2 is associated with postprandial clearance of triglyceride-rich remnant particles and triglyceride levels in healthy subjects.

Authors:
Niina Matikainen Maria Antonella Burza Stefano Romeo Antti Hakkarainen Martin Adiels Lasse Folkersen Per Eriksson Nina Lundbom Ewa Ehrenborg Marju Orho-Melander Marja-Riitta Taskinen Jan Borén

PLoS One 2013 20;8(11):e79473. Epub 2013 Nov 20.

HUCH Heart and Lung Centre, Cardiovascular Research Group, Helsinki University Central Hospital, Diabetes & Obesity, University of Helsinki, Helsinki, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079473PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835823PMC
September 2014

Monotherapy with the PCSK9 inhibitor alirocumab versus ezetimibe in patients with hypercholesterolemia: results of a 24 week, double-blind, randomized Phase 3 trial.

Authors:
Eli M Roth Marja-Riitta Taskinen Henry N Ginsberg John J P Kastelein Helen M Colhoun Jennifer G Robinson Laurence Merlet Robert Pordy Marie T Baccara-Dinet

Int J Cardiol 2014 Sep 2;176(1):55-61. Epub 2014 Jul 2.

Sanofi, Montpellier, France.

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http://dx.doi.org/10.1016/j.ijcard.2014.06.049DOI Listing
September 2014

The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management.

Authors:
Robert A Hegele Henry N Ginsberg M John Chapman Børge G Nordestgaard Jan Albert Kuivenhoven Maurizio Averna Jan Borén Eric Bruckert Alberico L Catapano Olivier S Descamps G Kees Hovingh Steve E Humphries Petri T Kovanen Luis Masana Päivi Pajukanta Klaus G Parhofer Frederick J Raal Kausik K Ray Raul D Santos Anton F H Stalenhoef Erik Stroes Marja-Riitta Taskinen Anne Tybjærg-Hansen Gerald F Watts Olov Wiklund

Lancet Diabetes Endocrinol 2014 Aug 23;2(8):655-66. Epub 2013 Dec 23.

Department of Cardiology, Wallenberg Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/S2213-8587(13)70191-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201123PMC
August 2014

HDL-C and HDL-C/ApoA-I predict long-term progression of glycemia in established type 2 diabetes.

Authors:
Boris Waldman Alicia J Jenkins Timothy M E Davis Marja-Riitta Taskinen Russell Scott Rachel L O'Connell Val J Gebski Martin K C Ng Anthony C Keech

Diabetes Care 2014 Aug 7;37(8):2351-8. Epub 2014 May 7.

NHMRC Clinical Trials Centre, Sydney Medical School, University of Sydney, Sydney, AustraliaDepartment of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia.

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http://dx.doi.org/10.2337/dc13-2738DOI Listing
August 2014

Different lipid variables predict incident coronary artery disease in patients with type 1 diabetes with or without diabetic nephropathy: the FinnDiane study.

Authors:
Nina Tolonen Carol Forsblom Ville-Petteri Mäkinen Valma Harjutsalo Daniel Gordin Maija Feodoroff Niina Sandholm Lena M Thorn Johan Wadén Marja-Riitta Taskinen Per-Henrik Groop

Diabetes Care 2014 Aug 30;37(8):2374-82. Epub 2014 May 30.

Folkhälsan Institute of Genetics, Folkhälsan Research Center, University of Helsinki, Helsinki, FinlandDivision of Nephrology, Department of Medicine, Helsinki University Central Hospital, Helsinki, FinlandResearch Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki, FinlandBaker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

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http://care.diabetesjournals.org/lookup/doi/10.2337/dc13-287
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http://dx.doi.org/10.2337/dc13-2873DOI Listing
August 2014

Hepatic lipogenesis and a marker of hepatic lipid oxidation, predict postprandial responses of triglyceride-rich lipoproteins.

Authors:
Niina Matikainen Martin Adiels Sanni Söderlund Sanna Stennabb Tytti Ahola Antti Hakkarainen Jan Borén Marja-Riitta Taskinen

Obesity (Silver Spring) 2014 Aug 28;22(8):1854-9. Epub 2014 May 28.

Department of Medicine, Cardiovascular Research Unit, Diabetes and Obesity Research Program, Heart and Lung Center, University of Helsinki, Finland; Division of Endocrinology, Helsinki University Central Hospital, University of Helsinki, Finland.

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http://dx.doi.org/10.1002/oby.20781DOI Listing
August 2014

Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society.

Authors:
Marina Cuchel Eric Bruckert Henry N Ginsberg Frederick J Raal Raul D Santos Robert A Hegele Jan Albert Kuivenhoven Børge G Nordestgaard Olivier S Descamps Elisabeth Steinhagen-Thiessen Anne Tybjærg-Hansen Gerald F Watts Maurizio Averna Catherine Boileau Jan Borén Alberico L Catapano Joep C Defesche G Kees Hovingh Steve E Humphries Petri T Kovanen Luis Masana Päivi Pajukanta Klaus G Parhofer Kausik K Ray Anton F H Stalenhoef Erik Stroes Marja-Riitta Taskinen Albert Wiegman Olov Wiklund M John Chapman

Eur Heart J 2014 Aug 22;35(32):2146-57. Epub 2014 Jul 22.

Institute for Translational Medicine and Therapeutics, University of Pennsylvania, 8039 Maloney Building, 3600 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/eurheartj/ehu274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139706PMC
August 2014

Cardiac steatosis in patients with dilated cardiomyopathy.

Authors:
Marit Granér Markku O Pentikäinen Kristofer Nyman Reijo Siren Jesper Lundbom Antti Hakkarainen Kirsi Lauerma Nina Lundbom Markku S Nieminen Max Petzold Marja-Riitta Taskinen

Heart 2014 Jul 24;100(14):1107-12. Epub 2014 Apr 24.

Division of Cardiology, Diabetes and Obesity Research Program, Heart and Lung Center, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1136/heartjnl-2013-304961DOI Listing
July 2014

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.

Authors:
Arthur Ko Rita M Cantor Daphna Weissglas-Volkov Elina Nikkola Prasad M V Linga Reddy Janet S Sinsheimer Bogdan Pasaniuc Robert Brown Marcus Alvarez Alejandra Rodriguez Rosario Rodriguez-Guillen Ivette C Bautista Olimpia Arellano-Campos Linda L Muñoz-Hernández Veikko Salomaa Jaakko Kaprio Antti Jula Matti Jauhiainen Markku Heliövaara Olli Raitakari Terho Lehtimäki Johan G Eriksson Markus Perola Kirk E Lohmueller Niina Matikainen Marja-Riitta Taskinen Maribel Rodriguez-Torres Laura Riba Teresa Tusie-Luna Carlos A Aguilar-Salinas Päivi Pajukanta

Nat Commun 2014 Jun 2;5:3983. Epub 2014 Jun 2.

1] Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA [2] Molecular Biology Institute at UCLA, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/ncomms4983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062071PMC
June 2014

Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals.

Authors:
Mariann I Lassenius Ville-Petteri Mäkinen Christopher L Fogarty Lina Peräneva Matti Jauhiainen Pirkko J Pussinen Marja-Riitta Taskinen Juha Kirveskari Outi Vaarala Janne K Nieminen Sohvi Hörkkö Antti J Kangas Pasi Soininen Mika Ala-Korpela Daniel Gordin Aila J Ahola Carol Forsblom Per-Henrik Groop Markku Lehto

Nutr Metab (Lond) 2014 13;11:28. Epub 2014 Jun 13.

Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum, Helsinki, Finland ; Department of Medicine, Division of Nephrology, Helsinki University Central Hospital, Helsinki, Finland ; Diabetes & Obesity Research Program, Research Program's Unit, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1186/1743-7075-11-28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067102PMC
June 2014

Postprandial hypertriglyceridemia as a coronary risk factor.

Authors:
Jan Borén Niina Matikainen Martin Adiels Marja-Riitta Taskinen

Clin Chim Acta 2014 Apr 6;431:131-42. Epub 2014 Feb 6.

HUCH Heart and Lung Centre, Research Programs Unit Diabetes and Obesity, Cardiovascular Research Group, Finland.

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http://dx.doi.org/10.1016/j.cca.2014.01.015DOI Listing
April 2014

Comment to the position paper on global recommendations for the management of dyslipidemia developed by the International Atherosclerosis Society (IAS).

Authors:
Alberico L Catapano M J Chapman Guy de Backer Marja-Riitta Taskinen Zeljko Reiner Olov Wiklund

Atherosclerosis 2014 Apr 21;233(2):508-9. Epub 2014 Jan 21.

University of Milan, 20133 Milano, Italy.

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.12.050DOI Listing
April 2014

Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society.

Authors:
Børge G Nordestgaard M John Chapman Steve E Humphries Henry N Ginsberg Luis Masana Olivier S Descamps Olov Wiklund Robert A Hegele Frederick J Raal Joep C Defesche Albert Wiegman Raul D Santos Gerald F Watts Klaus G Parhofer G Kees Hovingh Petri T Kovanen Catherine Boileau Maurizio Averna Jan Borén Eric Bruckert Alberico L Catapano Jan Albert Kuivenhoven Päivi Pajukanta Kausik Ray Anton F H Stalenhoef Erik Stroes Marja-Riitta Taskinen Anne Tybjærg-Hansen

Eur Heart J 2013 Dec 15;34(45):3478-90a. Epub 2013 Aug 15.

Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, DK-2730 Herlev, Copenhagen, Denmark.

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http://dx.doi.org/10.1093/eurheartj/eht273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844152PMC
December 2013

Efficacy and safety of linagliptin in subjects with type 2 diabetes mellitus and poor glycemic control: pooled analysis of data from three placebo-controlled phase III trials.

Authors:
Stefano Del Prato Marja-Riitta Taskinen David R Owens Maximilian von Eynatten Angela Emser Yan Gong Silvia Chiavetta Sanjay Patel Hans-Juergen Woerle

J Diabetes Complications 2013 May-Jun;27(3):274-9. Epub 2013 Feb 9.

Department of Endocrinology and Metabolism, Section of Diabetes, University of Pisa, Pisa, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S10568727120033
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http://dx.doi.org/10.1016/j.jdiacomp.2012.11.008DOI Listing
November 2013

Cardiac steatosis and left ventricular function in men with metabolic syndrome.

Authors:
Kristofer Nyman Marit Granér Markku O Pentikäinen Jesper Lundbom Antti Hakkarainen Reijo Sirén Markku S Nieminen Marja-Riitta Taskinen Nina Lundbom Kirsi Lauerma

J Cardiovasc Magn Reson 2013 Nov 14;15:103. Epub 2013 Nov 14.

Department of Radiology, HUS Medical Imaging Center, Helsinki University Central Hospital and University of Helsinki, Stenbäckinkatu 11, BOX 281, Helsinki FI-00029 HUS, Finland.

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http://dx.doi.org/10.1186/1532-429X-15-103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842676PMC
November 2013

Diagnostic efficacy of myeloperoxidase to identify acute coronary syndrome in subjects with chest pain.

Authors:
Marit Granér Emmi Tikkanen Olga Rimpilä Helena Tikkanen Samuli Ripatti Marja-Liisa Lokki Markku S Nieminen Marja-Riitta Taskinen Juha Sinisalo

Ann Med 2013 Jun 8;45(4):322-7. Epub 2013 May 8.

Heart and Lung Center, Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.3109/07853890.2013.783996DOI Listing
June 2013

Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

Authors:
Daphna Weissglas-Volkov Carlos A Aguilar-Salinas Elina Nikkola Kerry A Deere Ivette Cruz-Bautista Olimpia Arellano-Campos Linda Liliana Muñoz-Hernandez Lizeth Gomez-Munguia Maria Luisa Ordoñez-Sánchez Prasad M V Linga Reddy Aldons J Lusis Niina Matikainen Marja-Riitta Taskinen Laura Riba Rita M Cantor Janet S Sinsheimer Teresa Tusie-Luna Päivi Pajukanta

J Med Genet 2013 May 15;50(5):298-308. Epub 2013 Mar 15.

Department of Human Genetics, David Geffen School of Medicine at UCLA, Gonda Center, Room 6335B, 695 Charles E. Young Drive South, Los Angeles, CA 90095-7088, USA.

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http://dx.doi.org/10.1136/jmedgenet-2012-101461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917605PMC
May 2013

Genomic, transcriptomic, and lipidomic profiling highlights the role of inflammation in individuals with low high-density lipoprotein cholesterol.

Authors:
Pirkka-Pekka Laurila Ida Surakka Antti-Pekka Sarin Laxman Yetukuri Tuulia Hyötyläinen Sanni Söderlund Jussi Naukkarinen Jing Tang Johannes Kettunen Daniel B Mirel Jarkko Soronen Terho Lehtimäki Aimo Ruokonen Christian Ehnholm Johan G Eriksson Veikko Salomaa Antti Jula Olli T Raitakari Marjo-Riitta Järvelin Aarno Palotie Leena Peltonen Matej Oresic Matti Jauhiainen Marja-Riitta Taskinen Samuli Ripatti

Arterioscler Thromb Vasc Biol 2013 Apr 14;33(4):847-57. Epub 2013 Feb 14.

Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Finland.

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http://dx.doi.org/10.1161/ATVBAHA.112.300733DOI Listing
April 2013

Cardiac steatosis associates with visceral obesity in nondiabetic obese men.

Authors:
Marit Granér Reijo Siren Kristofer Nyman Jesper Lundbom Antti Hakkarainen Markku O Pentikäinen Kirsi Lauerma Nina Lundbom Martin Adiels Markku S Nieminen Marja-Riitta Taskinen

J Clin Endocrinol Metab 2013 Mar 15;98(3):1189-97. Epub 2013 Feb 15.

Department of Medicine, Division of Cardiology, Helsinki University Central Hospital, Haartmaninkatu 4, FIN-00290 HUCH, Finland.

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http://dx.doi.org/10.1210/jc.2012-3190DOI Listing
March 2013

A continuous-time adaptive particle filter for estimations under measurement time uncertainties with an application to a plasma-leucine mixed effects model.

Authors:
Annette Krengel Jan Hauth Marja-Riitta Taskinen Martin Adiels Mats Jirstrand

BMC Syst Biol 2013 Jan 19;7. Epub 2013 Jan 19.

Fraunhofer-Institut für Techno- und Wirtschaftsmathematik (ITWM; Fraunhofer Institute for Industrial Mathematics), Kaiserslautern, Germany.

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http://dx.doi.org/10.1186/1752-0509-7-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848953PMC
January 2013

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro.

Authors:
Carlo Pirazzi Martin Adiels Maria Antonella Burza Rosellina Margherita Mancina Malin Levin Marcus Ståhlman Marja-Riitta Taskinen Marju Orho-Melander Jeanna Perman Arturo Pujia Linda Andersson Cristina Maglio Tiziana Montalcini Olov Wiklund Jan Borén Stefano Romeo

J Hepatol 2012 Dec 6;57(6):1276-82. Epub 2012 Aug 6.

Sahlgrenska Center for Cardiovascular and Metabolic Research/Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.jhep.2012.07.030DOI Listing
December 2012

Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.

Authors:
Michael Inouye Samuli Ripatti Johannes Kettunen Leo-Pekka Lyytikäinen Niku Oksala Pirkka-Pekka Laurila Antti J Kangas Pasi Soininen Markku J Savolainen Jorma Viikari Mika Kähönen Markus Perola Veikko Salomaa Olli Raitakari Terho Lehtimäki Marja-Riitta Taskinen Marjo-Riitta Järvelin Mika Ala-Korpela Aarno Palotie Paul I W de Bakker

PLoS Genet 2012 16;8(8):e1002907. Epub 2012 Aug 16.

Medical Systems Biology, Departments of Pathology and of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.plos.org/10.1371/journal.pgen.1002907
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http://dx.doi.org/10.1371/journal.pgen.1002907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420921PMC
December 2012

Management of dyslipidemias in the presence of the metabolic syndrome or type 2 diabetes.

Authors:
Niina Matikainen Marja-Riitta Taskinen

Curr Cardiol Rep 2012 Dec;14(6):721-31

Department of Medicine, Division of Endocrinology, Helsinki University Central Hospital, University of Helsinki, Finland.

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http://dx.doi.org/10.1007/s11886-012-0309-3DOI Listing
December 2012

Metabolomic analysis of polar metabolites in lipoprotein fractions identifies lipoprotein-specific metabolic profiles and their association with insulin resistance.

Authors:
Tuulia Hyötyläinen Ismo Mattila Susanne K Wiedmer Artturi Koivuniemi Marja-Riitta Taskinen Hannele Yki-Järvinen Matej Orešič

Mol Biosyst 2012 Oct;8(10):2559-65

VTT Technical Research Centre of Finland, Tietotie 2, P.O. Box 1000, FIN-02044 VTT, Espoo, Finland.

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http://xlink.rsc.org/?DOI=c2mb25115a
Publisher Site
http://dx.doi.org/10.1039/c2mb25115aDOI Listing
October 2012

Diabetes as a case study of chronic disease management with a personalized approach: the role of a structured feedback loop.

Authors:
Antonio Ceriello László Barkai Jens Sandahl Christiansen Leszek Czupryniak Ramon Gomis Kari Harno Bernhard Kulzer Johnny Ludvigsson Zuzana Némethyová David Owens Oliver Schnell Tsvetalina Tankova Marja-Riitta Taskinen Bruno Vergès Raimund Weitgasser Johan Wens

Diabetes Res Clin Pract 2012 Oct 20;98(1):5-10. Epub 2012 Aug 20.

Insititut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Hospital Clínic Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.diabres.2012.07.005DOI Listing
October 2012

[New European clinical guidelines on dyslipidemias].

Authors:
Niina Matikainen Marja-Riitta Taskinen

Duodecim 2012 ;128(16):1651-62

HUS, Peijaksen sairaala, endokrinologian klinikka ja Biomedicum, kardiovaskulaarisairauksien tutkimusyksikkö.

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October 2012

Statins are diabetogenic--myth or reality?

Authors:
Naveed Sattar Marja-Riitta Taskinen

Atheroscler Suppl 2012 Aug 19;13(1):1-10. Epub 2012 Jul 19.

Institute of Cardiovascular & Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University Of Glasgow, 126 University Place, Glasgow G12 8TA, UK.

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http://dx.doi.org/10.1016/j.atherosclerosissup.2012.06.001DOI Listing
August 2012

Transgenic expression and genetic variation of Lmf1 affect LPL activity in mice and humans.

Authors:
Maryam Hosseini Nicole Ehrhardt Daphna Weissglas-Volkov Ching-Mei Lai Hui Z Mao Jo-Ling Liao Elina Nikkola André Bensadoun Marja-Riitta Taskinen Mark H Doolittle Päivi Pajukanta Miklós Péterfy

Arterioscler Thromb Vasc Biol 2012 May 16;32(5):1204-10. Epub 2012 Feb 16.

Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1161/ATVBAHA.112.245696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331946PMC
May 2012

Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity.

Authors:
Martin Adiels Niina Matikainen Jukka Westerbacka Sanni Söderlund Thomas Larsson Sven-Olof Olofsson Jan Borén Marja-Riitta Taskinen

Atherosclerosis 2012 May 7;222(1):222-8. Epub 2012 Feb 7.

Sahlgrenska Center for Cardiovascular and Metabolic Research/Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.02.001DOI Listing
May 2012

Glycemic control over 5 years in 4,900 people with type 2 diabetes: real-world diabetes therapy in a clinical trial cohort.

Authors:
James D Best Paul L Drury Timothy M E Davis Marja-Riitta Taskinen Y Antero Kesäniemi Russell Scott Christopher Pardy Merryn Voysey Anthony C Keech

Diabetes Care 2012 May 19;35(5):1165-70. Epub 2012 Mar 19.

Department of Medicine, University of Melbourne Medical School, St. Vincent’s Hospital, Melbourne, Victoria, Australia.

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http://care.diabetesjournals.org/cgi/doi/10.2337/dc11-1307
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http://dx.doi.org/10.2337/dc11-1307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329812PMC
May 2012

Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci.

Authors:
Taru Tukiainen Johannes Kettunen Antti J Kangas Leo-Pekka Lyytikäinen Pasi Soininen Antti-Pekka Sarin Emmi Tikkanen Paul F O'Reilly Markku J Savolainen Kimmo Kaski Anneli Pouta Antti Jula Terho Lehtimäki Mika Kähönen Jorma Viikari Marja-Riitta Taskinen Matti Jauhiainen Johan G Eriksson Olli Raitakari Veikko Salomaa Marjo-Riitta Järvelin Markus Perola Aarno Palotie Mika Ala-Korpela Samuli Ripatti

Hum Mol Genet 2012 Mar 9;21(6):1444-55. Epub 2011 Dec 9.

Institute for Molecular Medicine Finland FIMM, Helsinki University Hospital, FI-00014 University of Helsinki, Helsinki, Finland.

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March 2012

Decrease in circulating fibroblast growth factor 21 after an oral fat load is related to postprandial triglyceride-rich lipoproteins and liver fat.

Authors:
Niina Matikainen Marja-Riitta Taskinen Sanna Stennabb Nina Lundbom Antti Hakkarainen Kirsi Vaaralahti Taneli Raivio

Eur J Endocrinol 2012 Mar 21;166(3):487-92. Epub 2011 Dec 21.

Division of Cardiology Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, University of Helsinki, PO Box 700, FIN-00029 Helsinki, Finland.

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http://dx.doi.org/10.1530/EJE-11-0783DOI Listing
March 2012

High density lipoprotein structural changes and drug response in lipidomic profiles following the long-term fenofibrate therapy in the FIELD substudy.

Authors:
Laxman Yetukuri Ilkka Huopaniemi Artturi Koivuniemi Marianna Maranghi Anne Hiukka Heli Nygren Samuel Kaski Marja-Riitta Taskinen Ilpo Vattulainen Matti Jauhiainen Matej Orešič

PLoS One 2011 24;6(8):e23589. Epub 2011 Aug 24.

Technical Research Centre of Finland, Espoo, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023589PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160907PMC
January 2012

Dietary omega-3 polyunsaturated fatty acid intake is related to a protective high-density lipoprotein subspecies profile independent of genetic effects: a monozygotic twin pair study.

Authors:
Leonie H Bogl Marianna Maranghi Aila Rissanen Jaakko Kaprio Marja-Riitta Taskinen Kirsi H Pietiläinen

Atherosclerosis 2011 Dec 17;219(2):880-6. Epub 2011 Sep 17.

The Finnish Twin Cohort Study, Hjelt Institute, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.09.010DOI Listing
December 2011

[ESC/EAS Guidelines for the management of dyslipidaemias].

Authors:
Željko Reiner Alberico L Catapano Guy De Backer Ian Graham Marja-Riitta Taskinen Olov Wiklund Stefan Agewall Eduardo Alegría M John Chapman Paul Durrington Serap Erdine Julian Halcox Richard Hobbs Hobbs John Kjekshus Kjekshus Pasquale Perrone Filardi Gabriele Riccardi Robert F Storey Wood David

Rev Esp Cardiol 2011 Dec;64(12):1168.e1-1168.e60

University Hospital Center Zagreb, School of Medicine, University of Zagreb, Salata 2, 10 000 Zagreb, Croacia.

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http://dx.doi.org/10.1016/j.recesp.2011.09.014DOI Listing
December 2011

Macrophage cholesterol efflux to plasma and HDL in subjects with low and high homocysteine levels: a FIELD substudy.

Authors:
Marianna Maranghi Anne Hiukka Robert Badeau Jouko Sundvall Matti Jauhiainen Marja-Riitta Taskinen

Atherosclerosis 2011 Nov 25;219(1):259-65. Epub 2011 May 25.

Helsinki University Central Hospital, Biomedicum, Haartmaninkatu 8 PO Box 700, FIN-00029 Helsinki, Finland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.05.018DOI Listing
November 2011

Impact of metabolic syndrome and its components on cardiovascular disease event rates in 4900 patients with type 2 diabetes assigned to placebo in the FIELD randomised trial.

Authors:
Russell Scott Mark Donoghoe Gerald F Watts Richard O'Brien Christopher Pardy Marja-Riitta Taskinen Timothy M E Davis Peter G Colman Patrick Manning Gregory Fulcher Anthony C Keech

Cardiovasc Diabetol 2011 Nov 21;10:102. Epub 2011 Nov 21.

Lipid & Diabetes Research Group, Christchurch Hospital, Christchurch, New Zealand.

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http://dx.doi.org/10.1186/1475-2840-10-102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286386PMC
November 2011

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.

Authors:
Ida Surakka Aaron Isaacs Lennart C Karssen Pirkka-Pekka P Laurila Rita P S Middelberg Emmi Tikkanen Janina S Ried Claudia Lamina Massimo Mangino Wilmar Igl Jouke-Jan Hottenga Vasiliki Lagou Pim van der Harst Irene Mateo Leach Tõnu Esko Zoltán Kutalik Nicholas W Wainwright Maksim V Struchalin Antti-Pekka Sarin Antti J Kangas Jorma S Viikari Markus Perola Taina Rantanen Ann-Kristin Petersen Pasi Soininen Asa Johansson Nicole Soranzo Andrew C Heath Theodore Papamarkou Inga Prokopenko Anke Tönjes Florian Kronenberg Angela Döring Fernando Rivadeneira Grant W Montgomery John B Whitfield Mika Kähönen Terho Lehtimäki Nelson B Freimer Gonneke Willemsen Eco J C de Geus Aarno Palotie Manj S Sandhu Dawn M Waterworth Andres Metspalu Michael Stumvoll André G Uitterlinden Antti Jula Gerjan Navis Cisca Wijmenga Bruce H R Wolffenbuttel Marja-Riitta Taskinen Mika Ala-Korpela Jaakko Kaprio Kirsten O Kyvik Dorret I Boomsma Nancy L Pedersen Ulf Gyllensten James F Wilson Igor Rudan Harry Campbell Peter P Pramstaller Tim D Spector Jacqueline C M Witteman Johan G Eriksson Veikko Salomaa Ben A Oostra Olli T Raitakari H-Erich Wichmann Christian Gieger Marjo-Riitta Järvelin Nicholas G Martin Albert Hofman Mark I McCarthy Leena Peltonen Cornelia M van Duijn Yurii S Aulchenko Samuli Ripatti

PLoS Genet 2011 Oct 20;7(10):e1002333. Epub 2011 Oct 20.

Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1371/journal.pgen.1002333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197672PMC
October 2011

Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects.

Authors:
Marja-Riitta Taskinen Martin Adiels Jukka Westerbacka Sanni Söderlund Juhani Kahri Nina Lundbom Jesper Lundbom Antti Hakkarainen Sven-Olof Olofsson Marju Orho-Melander Jan Borén

Arterioscler Thromb Vasc Biol 2011 Sep 21;31(9):2144-50. Epub 2011 Jul 21.

Department of Medicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1161/ATVBAHA.111.224808DOI Listing
September 2011

Effects of exenatide on measures of β-cell function after 3 years in metformin-treated patients with type 2 diabetes.

Authors:
Mathijs C Bunck Anja Cornér Bjorn Eliasson Robert J Heine Rimma M Shaginian Marja-Riitta Taskinen Ulf Smith Hannele Yki-Järvinen Michaela Diamant

Diabetes Care 2011 Sep;34(9):2041-7

Department of Internal Medicine, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.2337/dc11-0291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161303PMC
September 2011

ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS).

Authors:
Zeljko Reiner Alberico L Catapano Guy De Backer Ian Graham Marja-Riitta Taskinen Olov Wiklund Stefan Agewall Eduardo Alegria M John Chapman Paul Durrington Serap Erdine Julian Halcox Richard Hobbs John Kjekshus Pasquale Perrone Filardi Gabriele Riccardi Robert F Storey David Wood

Eur Heart J 2011 Jul 28;32(14):1769-818. Epub 2011 Jun 28.

University Hospital Center Zagreb, School of Medicine, University of Zagreb, Salata 2, 10 000 Zagreb, Croatia.

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http://dx.doi.org/10.1093/eurheartj/ehr158DOI Listing
July 2011

ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS).

Authors:
Alberico L Catapano Zeljko Reiner Guy De Backer Ian Graham Marja-Riitta Taskinen Olov Wiklund Stefan Agewall Eduardo Alegria M John Chapman Paul Durrington Serap Erdine Julian Halcox Richard Hobbs John Kjekshus Pasquale Perrone Filardi Gabriele Riccardi Robert F Storey David Wood

Atherosclerosis 2011 Jul;217 Suppl 1:S1-44

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.06.012DOI Listing
July 2011

ESC/EAS Guidelines for the management of dyslipidaemias The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS).

Authors:
Alberico L Catapano Zeljko Reiner Guy De Backer Ian Graham Marja-Riitta Taskinen Olov Wiklund Stefan Agewall Eduardo Alegria M John Chapman Paul Durrington Serap Erdine Julian Halcox Richard Hobbs John Kjekshus Pasquale Perrone Filardi Gabriele Riccardi Robert F Storey David Wood

Atherosclerosis 2011 Jul;217(1):3-46

Department of Pharmacological Science, University of Milan, Milano, Italy.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.06.028DOI Listing
July 2011

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management.

Authors:
M John Chapman Henry N Ginsberg Pierre Amarenco Felicita Andreotti Jan Borén Alberico L Catapano Olivier S Descamps Edward Fisher Petri T Kovanen Jan Albert Kuivenhoven Philippe Lesnik Luis Masana Børge G Nordestgaard Kausik K Ray Zeljko Reiner Marja-Riitta Taskinen Lale Tokgözoglu Anne Tybjærg-Hansen Gerald F Watts

Eur Heart J 2011 Jun 29;32(11):1345-61. Epub 2011 Apr 29.

European Atherosclerosis Society, INSERM UMR-S939, Pitié-Salpetriere University Hospital, Paris 75651, France.

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http://dx.doi.org/10.1093/eurheartj/ehr112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105250PMC
June 2011

Long-TE 1H MRS suggests that liver fat is more saturated than subcutaneous and visceral fat.

Authors:
Jesper Lundbom Antti Hakkarainen Sanni Söderlund Jukka Westerbacka Nina Lundbom Marja-Riitta Taskinen

NMR Biomed 2011 Apr 6;24(3):238-45. Epub 2010 Sep 6.

Department of Medicine, Division of Cardiology, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1002/nbm.1580DOI Listing
April 2011

Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia.

Authors:
Sandrine Caron An Verrijken Ilse Mertens Carolina Huaman Samanez Gisèle Mautino Joel T Haas Daniel Duran-Sandoval Janne Prawitt Sven Francque Emmanuelle Vallez Anne Muhr-Tailleux Isabelle Berard Folkert Kuipers Jan A Kuivenhoven Sudha B Biddinger Marja-Riitta Taskinen Luc Van Gaal Bart Staels

Arterioscler Thromb Vasc Biol 2011 Mar 23;31(3):513-9. Epub 2010 Dec 23.

University Lille Nord de France, Lille, France.

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http://dx.doi.org/10.1161/ATVBAHA.110.220723DOI Listing
March 2011

Lipoprotein(a) as a cardiovascular risk factor: current status.

Authors:
Børge G Nordestgaard M John Chapman Kausik Ray Jan Borén Felicita Andreotti Gerald F Watts Henry Ginsberg Pierre Amarenco Alberico Catapano Olivier S Descamps Edward Fisher Petri T Kovanen Jan Albert Kuivenhoven Philippe Lesnik Luis Masana Zeljko Reiner Marja-Riitta Taskinen Lale Tokgözoglu Anne Tybjærg-Hansen

Eur Heart J 2010 Dec 21;31(23):2844-53. Epub 2010 Oct 21.

Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, DK-2730 Herlev, Denmark.

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http://dx.doi.org/10.1093/eurheartj/ehq386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295201PMC
December 2010

Increased apolipoprotein E level and reduced high-density lipoprotein mean particle size associate with low high-density lipoprotein cholesterol and features of metabolic syndrome.

Authors:
Sanni Söderlund Hiroshi Watanabe Christian Ehnholm Matti Jauhiainen Marja-Riitta Taskinen

Metabolism 2010 Oct 6;59(10):1502-9. Epub 2010 Mar 6.

Division of Cardiology, Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Biomedicum, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.metabol.2010.01.015DOI Listing
October 2010

One-year treatment with exenatide vs. insulin glargine: effects on postprandial glycemia, lipid profiles, and oxidative stress.

Authors:
Mathijs C Bunck Anja Cornér Bjorn Eliasson Robert J Heine Rimma M Shaginian Yan Wu Ping Yan Ulf Smith Hannele Yki-Järvinen Michaela Diamant Marja-Riitta Taskinen

Atherosclerosis 2010 Sep 29;212(1):223-9. Epub 2010 Apr 29.

Department of Internal Medicine, Section of Endocrinology, Diabetes Center, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.04.024DOI Listing
September 2010

An immune response network associated with blood lipid levels.

Authors:
Michael Inouye Kaisa Silander Eija Hamalainen Veikko Salomaa Kennet Harald Pekka Jousilahti Satu Männistö Johan G Eriksson Janna Saarela Samuli Ripatti Markus Perola Gert-Jan B van Ommen Marja-Riitta Taskinen Aarno Palotie Emmanouil T Dermitzakis Leena Peltonen

PLoS Genet 2010 Sep 9;6(9):e1001113. Epub 2010 Sep 9.

Department of Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1001113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936545PMC
September 2010

Effect of HDL composition and particle size on the resistance of HDL to the oxidation.

Authors:
Nakanishi Shuhei Sanni Söderlund Matti Jauhiainen Marja-Riitta Taskinen

Lipids Health Dis 2010 Sep 23;9:104. Epub 2010 Sep 23.

Division of Cardiology, Department of Medicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1186/1476-511X-9-104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954910PMC
September 2010

Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.

Authors:
Mathijs C Bunck Michaela Diamant Bjorn Eliasson Anja Cornér Rimma M Shaginian Robert J Heine Marja-Riitta Taskinen Hannele Yki-Järvinen Ulf Smith

Diabetes Care 2010 Aug 27;33(8):1734-7. Epub 2010 Apr 27.

Department of Internal Medicine, Section of Endocrinology, Diabetes Center, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.2337/dc09-2361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909051PMC
August 2010

Composition and lipid spatial distribution of HDL particles in subjects with low and high HDL-cholesterol.

Authors:
Laxman Yetukuri Sanni Söderlund Artturi Koivuniemi Tuulikki Seppänen-Laakso Perttu S Niemelä Marja Hyvönen Marja-Riitta Taskinen Ilpo Vattulainen Matti Jauhiainen Matej Oresic

J Lipid Res 2010 Aug 29;51(8):2341-51. Epub 2010 Apr 29.

VTT Technical Research Centre of Finland, Espoo, Finland.

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http://dx.doi.org/10.1194/jlr.M006494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903811PMC
August 2010

PPARalpha: an emerging therapeutic target in diabetic microvascular damage.

Authors:
Anne Hiukka Marianna Maranghi Niina Matikainen Marja-Riitta Taskinen

Nat Rev Endocrinol 2010 Aug 22;6(8):454-63. Epub 2010 Jun 22.

Division of Cardiology, Department of Medicine, Helsinki University Central Hospital and Biomedicum, Haartmaninkatu 8, 00029 Helsinki, Finland.

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http://dx.doi.org/10.1038/nrendo.2010.89DOI Listing
August 2010

Postprandial lipid and apolipoprotein responses following three consecutive meals associate with liver fat content in type 2 diabetes and the metabolic syndrome.

Authors:
Maarten E Tushuizen Petra J Pouwels Saskia Bontemps Cees Rustemeijer Niina Matikainen Robert J Heine Marja-Riitta Taskinen Michaela Diamant

Atherosclerosis 2010 Jul 10;211(1):308-14. Epub 2010 Feb 10.

Department of Endocrinology/Diabetes Center, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.02.002DOI Listing
July 2010

CVD in women.

Authors:
Barbara V Howard Marja-Riitta Taskinen

Nutr Metab Cardiovasc Dis 2010 Jul 6;20(6):377-8. Epub 2010 Jul 6.

MedStar Health Research Institute, Georgetown University, Washington, DC, USA.

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http://dx.doi.org/10.1016/j.numecd.2010.02.011DOI Listing
July 2010

Characterizing human adipose tissue lipids by long echo time 1H-MRS in vivo at 1.5 Tesla: validation by gas chromatography.

Authors:
Jesper Lundbom Antti Hakkarainen Barbara Fielding Sanni Söderlund Jukka Westerbacka Marja-Riitta Taskinen Nina Lundbom

NMR Biomed 2010 Jun;23(5):466-72

Department of Medicine, Division of Cardiology, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1002/nbm.1483DOI Listing
June 2010

Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.

Authors:
Jussi Naukkarinen Ida Surakka Kirsi H Pietiläinen Aila Rissanen Veikko Salomaa Samuli Ripatti Hannele Yki-Järvinen Cornelia M van Duijn H-Erich Wichmann Jaakko Kaprio Marja-Riitta Taskinen Leena Peltonen

PLoS Genet 2010 Jun 3;6(6):e1000976. Epub 2010 Jun 3.

FIMM, Institute for Molecular Medicine Finland, University of Helsinki, Finland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880558PMC
June 2010

Reviewing statin therapy in diabetes--towards the best practise.

Authors:
Niina Matikainen Juhani Kahri Marja-Riitta Taskinen

Prim Care Diabetes 2010 Apr 19;4(1):9-15. Epub 2010 Feb 19.

Department of Medicine, University of Helsinki, Finland.

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http://dx.doi.org/10.1016/j.pcd.2010.01.005DOI Listing
April 2010

Optimization of N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide as a derivatization agent for determining isotopic enrichment of glycerol in very-low density lipoproteins.

Authors:
Martin Adiels Thomas Larsson Pauline Sutton Marja-Riitta Taskinen Jan Borén Barbara A Fielding

Rapid Commun Mass Spectrom 2010 Mar;24(5):586-92

Wallenberg Laboratory/Sahlgrenska Center for Cardiovascular and Metabolic Research, Göteborg University, 413 45 Göteborg, Sweden.

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http://dx.doi.org/10.1002/rcm.4422DOI Listing
March 2010