Marisa S Bartolomei

Marisa S Bartolomei

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H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice.

Physiol Rep 2019 Oct;7(19):e14244

Biomedical Engineering, Vanderbilt University, Nashville, Tennessee.

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http://dx.doi.org/10.14814/phy2.14244DOI Listing
October 2019

The effects of Assisted Reproductive Technologies on genomic imprinting in the placenta.

Placenta 2019 Sep 4;84:37-43. Epub 2019 Mar 4.

Epigenetics Institute, Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Smilow Center for Translational Research, 3400 Civic Center Blvd, Bldg 421, Philadelphia, PA, 19104-6058, USA. Electronic address:

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http://dx.doi.org/10.1016/j.placenta.2019.02.013DOI Listing
September 2019

Histone modification signatures in human sperm distinguish clinical abnormalities.

J Assist Reprod Genet 2019 Feb 5;36(2):267-275. Epub 2018 Nov 5.

Department of Cell and Developmental Biology, Perelman School of Medicine, 9-125 Smilow Center for Translational Research, University of Pennsylvania, 3400 Civic Center Blvd, Bldg 421, Philadelphia, PA, 19104-6058, USA.

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http://link.springer.com/10.1007/s10815-018-1354-7
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http://dx.doi.org/10.1007/s10815-018-1354-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420512PMC
February 2019

Imatinib treatments have long-term impact on placentation and embryo survival.

Sci Rep 2019 Feb 22;9(1):2535. Epub 2019 Feb 22.

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/s41598-019-39134-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385245PMC
February 2019

Evolving imprinting control regions: KRAB zinc fingers hold the key.

Genes Dev 2019 01;33(1-2):1-3

Epigenetics Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1101/gad.322990.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317316PMC
January 2019

Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting.

PLoS Genet 2019 01 9;15(1):e1007874. Epub 2019 Jan 9.

Department of Bioengineering, University of Pennsylvania, Skirkanich Hall, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342324PMC
January 2019

Mapping the diploid genome, one cell at a time.

Nat Struct Mol Biol 2018 11;25(11):994-995

Epigenetics Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://www.nature.com/articles/s41594-018-0149-y
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http://dx.doi.org/10.1038/s41594-018-0149-yDOI Listing
November 2018

TRPM7 and Ca3.2 channels mediate Ca influx required for egg activation at fertilization.

Proc Natl Acad Sci U S A 2018 10 15;115(44):E10370-E10378. Epub 2018 Oct 15.

Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709;

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http://dx.doi.org/10.1073/pnas.1810422115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217414PMC
October 2018

DNA methylation dynamics of genomic imprinting in mouse development.

Biol Reprod 2018 07;99(1):252-262

Epigenetics Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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https://academic.oup.com/biolreprod/article/99/1/252/4862468
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http://dx.doi.org/10.1093/biolre/ioy036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044325PMC
July 2018

In Inflamed Intestinal Tissues and Epithelial Cells, Interleukin 22 Signaling Increases Expression of H19 Long Noncoding RNA, Which Promotes Mucosal Regeneration.

Gastroenterology 2018 07 3;155(1):144-155. Epub 2018 Apr 3.

Center for Intestinal and Liver Inflammation Research, Stanley Manne Children's Research Institute, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.03.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475625PMC
July 2018

Rapamycin-independent IGF2 expression in Tsc2-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells.

PLoS One 2018 14;13(5):e0197105. Epub 2018 May 14.

Penn Center for Pulmonary Biology and Pulmonary, Allergy and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197105PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951544PMC
July 2018

Mice exposed to bisphenol A exhibit depressive-like behavior with neurotransmitter and neuroactive steroid dysfunction.

Horm Behav 2018 06 18;102:93-104. Epub 2018 May 18.

Epigenetics Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Excellence in Environmental Toxicology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yhbeh.2018.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261494PMC
June 2018

Assisted Reproductive Technologies and the Placenta: Clinical, Morphological, and Molecular Outcomes.

Semin Reprod Med 2018 05 13;36(3-04):240-248. Epub 2019 Mar 13.

Department of Cell and Developmental Biology, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1055/s-0038-1676640DOI Listing
May 2018

Endocrine-disrupting chemicals, epigenetics, and skeletal system dysfunction: exploration of links using bisphenol A as a model system.

Environ Epigenet 2018 Apr 26;4(2):dvy002. Epub 2018 Apr 26.

Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1093/eep/dvy002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920333PMC
April 2018

Imprinted gene dysregulation in a null mouse model is stochastic and variable in the germline and offspring.

Development 2018 03 29;145(7). Epub 2018 Mar 29.

University of Pennsylvania, Perelman School of Medicine, Department of Cell and Developmental Biology, SCTR 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA

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http://dx.doi.org/10.1242/dev.160622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963867PMC
March 2018

Obituary: Denise Barlow (1950-2017).

Development 2018 03 14;145(5). Epub 2018 Mar 14.

Department of Cell & Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

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http://dev.biologists.org/lookup/doi/10.1242/dev.164616
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http://dx.doi.org/10.1242/dev.164616DOI Listing
March 2018

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome.

J Vis Exp 2018 03 2(133). Epub 2018 Mar 2.

Clinical Research Division, Fred Hutchinson Cancer Research Center; Departments of Medicine and Biochemistry, University of Washington;

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http://dx.doi.org/10.3791/56398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931421PMC
March 2018

Sex- and Dose-Specific Effects of Maternal Bisphenol A Exposure on Pancreatic Islets of First- and Second-Generation Adult Mice Offspring.

Environ Health Perspect 2017 09 27;125(9):097022. Epub 2017 Sep 27.

Center for Research on Reproduction and Women's Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1289/EHP1674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915189PMC
September 2017

Bile Acids and Tryptophan Metabolism Are Novel Pathways Involved in Metabolic Abnormalities in BPA-Exposed Pregnant Mice and Male Offspring.

Endocrinology 2017 08;158(8):2533-2542

Epigenetics Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104.

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http://dx.doi.org/10.1210/en.2017-00046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551548PMC
August 2017

The superovulated environment, independent of embryo vitrification, results in low birthweight in a mouse model.

Biol Reprod 2017 Jul;97(1):133-142

Division of Reproductive Endocrinology and Infertility, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1093/biolre/iox067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248797PMC
July 2017

Can assisted reproductive technologies cause adult-onset disease? Evidence from human and mouse.

Reprod Toxicol 2017 03 26;68:72-84. Epub 2016 Jul 26.

Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2016.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269604PMC
March 2017

A Hox-Embedded Long Noncoding RNA: Is It All Hot Air?

PLoS Genet 2016 Dec 15;12(12):e1006485. Epub 2016 Dec 15.

HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157941PMC
December 2016

Morphologic and molecular changes in the placenta: what we can learn from environmental exposures.

Fertil Steril 2016 09 11;106(4):930-40. Epub 2016 Aug 11.

Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2016.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026950PMC
September 2016

Humanized H19/Igf2 locus reveals diverged imprinting mechanism between mouse and human and reflects Silver-Russell syndrome phenotypes.

Proc Natl Acad Sci U S A 2016 09 12;113(39):10938-43. Epub 2016 Sep 12.

Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047210PMC
http://dx.doi.org/10.1073/pnas.1603066113DOI Listing
September 2016

Morphokinetic Evaluation of Embryo Development in a Mouse Model: Functional and Molecular Correlates.

Biol Reprod 2016 Apr 24;94(4):84. Epub 2016 Feb 24.

Division of Reproductive Endocrinology and Infertility, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1095/biolreprod.115.134080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322449PMC
April 2016

Visualizing allele-specific expression in single cells reveals epigenetic mosaicism in an H19 loss-of-imprinting mutant.

Genes Dev 2016 Mar;30(5):567-78

Department of Bioengineering, University of Pennsylvania, Skirkanich Hall, Philadelphia, Pennsylvania 19104, USA;

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http://dx.doi.org/10.1101/gad.275958.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782050PMC
March 2016

CRISPR-Cas9-Mediated Genetic Screening in Mice with Haploid Embryonic Stem Cells Carrying a Guide RNA Library.

Cell Stem Cell 2015 Aug 9;17(2):221-32. Epub 2015 Jul 9.

Group of Epigenetic Reprogramming, State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; Shanghai Key Laboratory of Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; School of Life Science and Technology, Shanghai Tech University, Shanghai 200031, China. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.06.005DOI Listing
August 2015

Multigenerational and transgenerational inheritance of drug exposure: The effects of alcohol, opiates, cocaine, marijuana, and nicotine.

Prog Biophys Mol Biol 2015 Jul 1;118(1-2):21-33. Epub 2015 Apr 1.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pbiomolbio.2015.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459901PMC
July 2015

Multigenerational and transgenerational effects of endocrine disrupting chemicals: A role for altered epigenetic regulation?

Semin Cell Dev Biol 2015 Jul 28;43:66-75. Epub 2015 May 28.

Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, 9-123 Smilow Center for Translational Research, Philadelphia, PA 19104, United States; Center of Excellence in Environmental Toxicology, University of Pennsylvania Perelman School of Medicine, 1316 Biomedical Research Building II/III, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2015.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662893PMC
July 2015

Tissue-specific regulation and function of Grb10 during growth and neuronal commitment.

Proc Natl Acad Sci U S A 2015 Jun 3;112(22):6841-7. Epub 2014 Nov 3.

Department of Cell & Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104

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http://www.pnas.org/lookup/doi/10.1073/pnas.1411254111
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http://dx.doi.org/10.1073/pnas.1411254111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460511PMC
June 2015

Bisphenol a exposure disrupts metabolic health across multiple generations in the mouse.

Endocrinology 2015 Jun 25;156(6):2049-58. Epub 2015 Mar 25.

Department of Cell and Developmental Biology (M.S., F.X., M.S., M.S.B.), Center of Excellence in Environmental Toxicology (M.S., F.X., R.A.S., M.S.B.), Center for Research on Reproduction and Women's Health (M.S., F.X., A.B., R.A.S., M.S.B.), and Division of Neonatology (A.B., R.A.S.), Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104; and Division of Endocrinology and Metabolism (C.L.), The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104.

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http://dx.doi.org/10.1210/en.2014-2027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430620PMC
June 2015

Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.

Nature 2015 May;521(7552):E1-4

1] Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [2] Department of Neurology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [3] Veterans Affairs, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [4] Weill Cornell Autism Research Program, Weill Cornell Medical College, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/nature14444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684952PMC
May 2015

Characterization of BRD4 during mammalian postmeiotic sperm development.

Mol Cell Biol 2015 Apr 17;35(8):1433-48. Epub 2015 Feb 17.

Penn Epigenetics Program, Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA

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http://mcb.asm.org/content/early/2015/02/11/MCB.01328-14.ful
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http://mcb.asm.org/lookup/doi/10.1128/MCB.01328-14
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http://dx.doi.org/10.1128/MCB.01328-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372693PMC
April 2015

Epigenetics and imprinting in human disease.

Int J Dev Biol 2014 ;58(2-4):291-8

Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://www.intjdevbiol.com/paper.php?doi=140077mb
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http://dx.doi.org/10.1387/ijdb.140077mbDOI Listing
March 2015

Differential methylation of genes associated with cell adhesion in preeclamptic placentas.

PLoS One 2014 25;9(6):e100148. Epub 2014 Jun 25.

Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100148PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070941PMC
February 2015

Tissue-specific insulator function at H19/Igf2 revealed by deletions at the imprinting control region.

Hum Mol Genet 2014 Dec 2;23(23):6246-59. Epub 2014 Jul 2.

Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, 9-123 SCTR, 3400 Civic Center Boulevard, Philadelphia PA 19104, USA and

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http://dx.doi.org/10.1093/hmg/ddu344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222363PMC
December 2014

Epigenetics. You are what you eat, but what about your DNA?

Science 2014 Aug;345(6198):733-4

Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.1258654DOI Listing
August 2014

Genomic imprinting in development, growth, behavior and stem cells.

Development 2014 May;141(9):1805-13

Department of Cell & Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1242/dev.101428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994769PMC
May 2014

Chromatin regulators of genomic imprinting.

Biochim Biophys Acta 2014 Mar 15;1839(3):169-77. Epub 2013 Dec 15.

Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, 9-123 Smilow Center for Translational Research, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2013.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951659PMC
March 2014

Genomic imprinting in mammals.

Cold Spring Harb Perspect Biol 2014 Feb 1;6(2). Epub 2014 Feb 1.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, CeMM, 1090 Vienna, Austria.

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http://cshperspectives.cshlp.org/lookup/doi/10.1101/cshpersp
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http://dx.doi.org/10.1101/cshperspect.a018382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941233PMC
February 2014

CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation.

Nucleic Acids Res 2014 Jan 10;42(2):774-89. Epub 2013 Oct 10.

Department of Cell & Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA, Program of Gene Expression and Regulation, The Wistar Institute, Philadelphia, PA 19104, USA, Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA and Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA.

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http://dx.doi.org/10.1093/nar/gkt910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902912PMC
January 2014

Loss of DNMT1o disrupts imprinted X chromosome inactivation and accentuates placental defects in females.

PLoS Genet 2013 Nov 21;9(11):e1003873. Epub 2013 Nov 21.

Departments of Pharmacology & Therapeutics, Pediatrics and Human Genetics, Research Institute at The Montreal Children's Hospital of the McGill University Health Centre, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1003873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836718PMC
November 2013

Autism: A long genetic explanation.

Nature 2013 Sep 28;501(7465):36-7. Epub 2013 Aug 28.

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http://www.nature.com/articles/nature12553
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September 2013

Bisphenol a exposure disrupts genomic imprinting in the mouse.

PLoS Genet 2013 Apr 4;9(4):e1003401. Epub 2013 Apr 4.

Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.

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https://dx.plos.org/10.1371/journal.pgen.1003401
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http://dx.doi.org/10.1371/journal.pgen.1003401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616904PMC
April 2013

X-inactivation, imprinting, and long noncoding RNAs in health and disease.

Cell 2013 Mar;152(6):1308-23

Howard Hughes Medical Institute, Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.cell.2013.02.016DOI Listing
March 2013

Nonrandom X chromosome inactivation is influenced by multiple regions on the murine X chromosome.

Genetics 2012 Nov 10;192(3):1095-107. Epub 2012 Aug 10.

Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://genetics.org/content/genetics/192/3/1095.full.pdf
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http://www.genetics.org/cgi/doi/10.1534/genetics.112.144477
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http://dx.doi.org/10.1534/genetics.112.144477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522153PMC
November 2012

Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice.

Hum Mol Genet 2012 Oct 16;21(20):4460-72. Epub 2012 Jul 16.

Department of Biology, University of Texas, San Antonio, TX 78249, USA.

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http://dx.doi.org/10.1093/hmg/dds287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459467PMC
October 2012

Imprinted genes … and the number is?

PLoS Genet 2012 29;8(3):e1002601. Epub 2012 Mar 29.

Epigenetics Programme, The Babraham Institute, Cambridge, United Kingdom.

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https://dx.plos.org/10.1371/journal.pgen.1002601
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http://dx.doi.org/10.1371/journal.pgen.1002601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315456PMC
September 2012

Fertile offspring derived from mouse spermatogonial stem cells cryopreserved for more than 14 years.

Hum Reprod 2012 May 12;27(5):1249-59. Epub 2012 Mar 12.

Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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https://academic.oup.com/humrep/article-lookup/doi/10.1093/h
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http://dx.doi.org/10.1093/humrep/des077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329194PMC
May 2012

Genomic imprinting: recognition and marking of imprinted loci.

Curr Opin Genet Dev 2012 Apr 21;22(2):72-8. Epub 2011 Dec 21.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S0959437X110018
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http://dx.doi.org/10.1016/j.gde.2011.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314145PMC
April 2012

ZFP57: KAPturing DNA methylation at imprinted loci.

Mol Cell 2011 Nov;44(3):341-2

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.molcel.2011.10.008DOI Listing
November 2011

Nonallelic transcriptional roles of CTCF and cohesins at imprinted loci.

Mol Cell Biol 2011 Aug 31;31(15):3094-104. Epub 2011 May 31.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1128/MCB.01449-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147605PMC
August 2011

Mammalian genomic imprinting.

Cold Spring Harb Perspect Biol 2011 Jul 1;3(7). Epub 2011 Jul 1.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19063, USA.

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http://dx.doi.org/10.1101/cshperspect.a002592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119911PMC
July 2011

Novel cis-regulatory function in ICR-mediated imprinted repression of H19.

Dev Biol 2011 Jul 10;355(2):349-57. Epub 2011 May 10.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.ydbio.2011.04.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125397PMC
July 2011

A YY1 bridge for X inactivation.

Cell 2011 Jul;146(1):11-3

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.cell.2011.06.029DOI Listing
July 2011

Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo.

Dev Biol 2011 May 24;353(2):420-31. Epub 2011 Feb 24.

CeMM, Research Center for Molecular Medicine of the Austrian Academy of Science, Lazarettgasse 14, AKH-BT 25.3, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.ydbio.2011.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081948PMC
May 2011

Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development.

Biol Reprod 2010 Dec 18;83(6):1027-35. Epub 2010 Aug 18.

Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6018, USA.

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http://dx.doi.org/10.1095/biolreprod.110.086397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994328PMC
December 2010

Domain-specific response of imprinted genes to reduced DNMT1.

Mol Cell Biol 2010 Aug 14;30(16):3916-28. Epub 2010 Jun 14.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, CRB 363, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1128/MCB.01278-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916450PMC
August 2010

Defective imprint resetting in carriers of Robertsonian translocation Rb (8.12).

Mamm Genome 2010 Aug 25;21(7-8):377-87. Epub 2010 Jun 25.

Department of Human Genetics, McGill University, Montreal, QC, Canada.

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http://link.springer.com/10.1007/s00335-010-9271-9
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August 2010

CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features.

Genome Biol 2009 18;10(11):R131. Epub 2009 Nov 18.

Penn Center for Bioinformatics, Department of Genetics, 415 Curie Boulevard, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1186/gb-2009-10-11-r131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091324PMC
July 2010

Imprinting and epigenetic changes in the early embryo.

Mamm Genome 2009 Sep-Oct;20(9-10):532-43. Epub 2009 Sep 16.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, 415 Curie Blvd., Philadelphia, PA 19104-6148, USA.

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March 2010

Genomic imprinting: employing and avoiding epigenetic processes.

Genes Dev 2009 Sep;23(18):2124-33

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://genesdev.cshlp.org/cgi/doi/10.1101/gad.1841409
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751984PMC
September 2009

Genomic imprinting mechanisms in mammals.

Mutat Res 2008 Dec 20;647(1-2):77-85. Epub 2008 Aug 20.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.mrfmmm.2008.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645997PMC
December 2008

Regulation of imprinting in clusters: noncoding RNAs versus insulators.

Adv Genet 2008 ;61:207-23

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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November 2008

Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development.

Development 2008 Aug 9;135(16):2729-38. Epub 2008 Jul 9.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1242/dev.024539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596970PMC
August 2008

H19 in the pouch.

Nat Genet 2008 Aug;40(8):932-3

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http://dx.doi.org/10.1038/ng0808-932DOI Listing
August 2008

Genetic and epigenetic mechanisms combine to control MMP1 expression and its association with preterm premature rupture of membranes.

Hum Mol Genet 2008 Apr 4;17(8):1087-96. Epub 2008 Jan 4.

State Key Laboratory of Genetic Engineering, Institute of Genetics, Fudan University School of Life Science, Shanghai 200433, China.

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April 2008

Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators.

EMBO J 2008 Feb 24;27(4):654-66. Epub 2008 Jan 24.

Gene Regulation Program, The Wistar Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/emboj.2008.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262040PMC
February 2008

Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development.

Hum Mol Genet 2008 Jan 27;17(1):1-14. Epub 2007 Sep 27.

Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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January 2008

The transcriptional status but not the imprinting control region determines allele-specific histone modifications at the imprinted H19 locus.

Mol Cell Biol 2008 Jan 29;28(1):71-82. Epub 2007 Oct 29.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1128/MCB.01534-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223277PMC
January 2008

SnapShot: imprinted gene clusters.

Cell 2007 Sep;130(5):958

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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September 2007

Maintenance of paternal methylation and repression of the imprinted H19 gene requires MBD3.

PLoS Genet 2007 Aug 29;3(8):e137. Epub 2007 Jun 29.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.0030137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950162PMC
August 2007

X-tra! X-tra! News from the mouse X chromosome.

Dev Biol 2006 Oct 15;298(2):344-53. Epub 2006 Jul 15.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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October 2006

CTCF binding sites promote transcription initiation and prevent DNA methylation on the maternal allele at the imprinted H19/Igf2 locus.

Hum Mol Genet 2006 Oct 23;15(19):2945-54. Epub 2006 Aug 23.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.

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http://dx.doi.org/10.1093/hmg/ddl237DOI Listing
October 2006

DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages.

Development 2006 Sep 3;133(17):3411-8. Epub 2006 Aug 3.

Department of Molecular Genetics and Microbiology, PO Box 100266, University of Florida, Gainesville, FL 32610-0266, USA.

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http://dev.biologists.org/cgi/doi/10.1242/dev.02500
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September 2006

Identification of candidate maternal-effect genes through comparison of multiple microarray data sets.

Mamm Genome 2006 Sep 8;17(9):941-9. Epub 2006 Sep 8.

Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1007/s00335-006-0034-6DOI Listing
September 2006

Genetic control of X chromosome inactivation in mice: definition of the Xce candidate interval.

Genetics 2006 Aug 2;173(4):2103-10. Epub 2006 Apr 2.

Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA.

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http://dx.doi.org/10.1534/genetics.105.054882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569705PMC
August 2006

Strategies for dissecting epigenetic mechanisms in the mouse.

Nat Genet 2005 Nov;37(11):1194-200

Howard Hughes Medical Institute and Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://www.nature.com/articles/ng1664
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November 2005

Adult mice cloned from migrating primordial germ cells.

Proc Natl Acad Sci U S A 2005 Aug 29;102(32):11361-6. Epub 2005 Jul 29.

Institute for Biogenesis Research, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96822, USA.

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http://dx.doi.org/10.1073/pnas.0504943102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182132PMC
August 2005

X chromosome reactivation and regulation in cloned embryos.

Dev Biol 2005 Mar;279(2):525-40

Department of Cell and Developmental Biology, Howard Hughes Medical Institute, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Philadelphia, PA 19104-6148, USA.

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http://dx.doi.org/10.1016/j.ydbio.2005.01.016DOI Listing
March 2005

Evidence for genetic modifiers of postnatal lethality in PWS-IC deletion mice.

Hum Mol Genet 2004 Dec 30;13(23):2971-7. Epub 2004 Sep 30.

Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, FL 32610, USA.

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http://academic.oup.com/hmg/article/13/23/2971/625567/Eviden
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http://dx.doi.org/10.1093/hmg/ddh314DOI Listing
December 2004

Antagonism between DNA hypermethylation and enhancer-blocking activity at the H19 DMD is uncovered by CpG mutations.

Nat Genet 2004 Aug 25;36(8):883-8. Epub 2004 Jul 25.

Howard Hughes Medical Institute and Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://www.nature.com/articles/ng1399
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August 2004