Maris Kuningas

Maris Kuningas

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Maris Kuningas

Maris Kuningas

Publications by authors named "Maris Kuningas"

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Age- and sex-specific causal effects of adiposity on cardiovascular risk factors.

Diabetes 2015 May 23;64(5):1841-52. Epub 2015 Feb 23.

Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.

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http://diabetes.diabetesjournals.org/content/64/5/1841.full.
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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db14
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http://dx.doi.org/10.2337/db14-0988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407863PMC
May 2015

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.

Int J Epidemiol 2015 Apr 27;44(2):578-86. Epub 2015 May 27.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden, Estonian Genome Center, University of Tartu, Tartu, Estonia, Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands, EMGO Institute for Health and Care Research, Amsterdam, The Netherlands, Institute of Mathematical Statistics, University of Tartu, Tartu, Estonia, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, Leiden, The Netherlands, Department of Genetic Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Helsinki, Finland, Department of Neurology, and Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands, Inspectorate for Health Care, The Hague, The Netherlands, Queensland Brain Institute, University of Queensland, Brisbane, QLD, Australia, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia, Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, Division of Epidemiology, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK, Center for Life Course and Systems Epidemiology, University of Oulu, Oulu, Finland, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, Finland, Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland, MRC Health Protection Agency (HPE) Centre for Environment and Health, Imperial College London, London, UK, Unit of Primary Care, Oulu University Hospital, Oulu, Finland, Hjelt Institute, University of Helsinki,

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http://dx.doi.org/10.1093/ije/dyv094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553708PMC
April 2015

Association between trefoil factor 3 gene variants and idiopathic recurrent spontaneous abortion.

Reprod Biomed Online 2014 Dec 3;29(6):737-44. Epub 2014 Sep 3.

Department of Women's and Children's Health, Uppsala University, Uppsala University Hospital, Uppsala 751 85, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.rbmo.2014.08.007DOI Listing
December 2014

Variants of the IL-10 gene associate with muscle strength in elderly from rural Africa: a candidate gene study.

Aging Cell 2014 Oct 18;13(5):862-8. Epub 2014 Jul 18.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands.

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http://doi.wiley.com/10.1111/acel.12244
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http://dx.doi.org/10.1111/acel.12244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331746PMC
October 2014

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.

Authors:
Tove Fall Sara Hägg Reedik Mägi Alexander Ploner Krista Fischer Momoko Horikoshi Antti-Pekka Sarin Gudmar Thorleifsson Claes Ladenvall Mart Kals Maris Kuningas Harmen H M Draisma Janina S Ried Natalie R van Zuydam Ville Huikari Massimo Mangino Emily Sonestedt Beben Benyamin Christopher P Nelson Natalia V Rivera Kati Kristiansson Huei-Yi Shen Aki S Havulinna Abbas Dehghan Louise A Donnelly Marika Kaakinen Marja-Liisa Nuotio Neil Robertson Renée F A G de Bruijn M Arfan Ikram Najaf Amin Anthony J Balmforth Peter S Braund Alexander S F Doney Angela Döring Paul Elliott Tõnu Esko Oscar H Franco Solveig Gretarsdottir Anna-Liisa Hartikainen Kauko Heikkilä Karl-Heinz Herzig Hilma Holm Jouke Jan Hottenga Elina Hyppönen Thomas Illig Aaron Isaacs Bo Isomaa Lennart C Karssen Johannes Kettunen Wolfgang Koenig Kari Kuulasmaa Tiina Laatikainen Jaana Laitinen Cecilia Lindgren Valeriya Lyssenko Esa Läärä Nigel W Rayner Satu Männistö Anneli Pouta Wolfgang Rathmann Fernando Rivadeneira Aimo Ruokonen Markku J Savolainen Eric J G Sijbrands Kerrin S Small Jan H Smit Valgerdur Steinthorsdottir Ann-Christine Syvänen Anja Taanila Martin D Tobin Andre G Uitterlinden Sara M Willems Gonneke Willemsen Jacqueline Witteman Markus Perola Alun Evans Jean Ferrières Jarmo Virtamo Frank Kee David-Alexandre Tregouet Dominique Arveiler Philippe Amouyel Marco M Ferrario Paolo Brambilla Alistair S Hall Andrew C Heath Pamela A F Madden Nicholas G Martin Grant W Montgomery John B Whitfield Antti Jula Paul Knekt Ben Oostra Cornelia M van Duijn Brenda W J H Penninx George Davey Smith Jaakko Kaprio Nilesh J Samani Christian Gieger Annette Peters H Erich Wichmann Dorret I Boomsma Eco J C de Geus TiinaMaija Tuomi Chris Power Christopher J Hammond Tim D Spector Lars Lind Marju Orho-Melander Colin Neil Alexander Palmer Andrew D Morris Leif Groop Marjo-Riitta Järvelin Veikko Salomaa Erkki Vartiainen Albert Hofman Samuli Ripatti Andres Metspalu Unnur Thorsteinsdottir Kari Stefansson Nancy L Pedersen Mark I McCarthy Erik Ingelsson Inga Prokopenko

PLoS Med 2013 25;10(6):e1001474. Epub 2013 Jun 25.

Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1371/journal.pmed.1001474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692470PMC
March 2014

The association of trefoil factor 3 gene polymorphisms and haplotypes with unexplained female infertility: molecular insights into TFF3 regulation in receptive phase endometrium.

Hum Fertil (Camb) 2013 Dec 15;16(4):291-8. Epub 2013 Nov 15.

Department of Women's and Children's Health, Uppsala University, Uppsala University Hospital , Uppsala , Sweden.

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http://dx.doi.org/10.3109/14647273.2013.850747DOI Listing
December 2013

A genome-wide association study of depressive symptoms.

Biol Psychiatry 2013 Apr 3;73(7):667-78. Epub 2013 Jan 3.

Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.

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http://dx.doi.org/10.1016/j.biopsych.2012.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845085PMC
April 2013

Evidence of inbreeding depression on human height.

PLoS Genet 2012 19;8(7):e1002655. Epub 2012 Jul 19.

Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400549PMC
January 2013

The relationship between fertility and lifespan in humans.

Age (Dordr) 2011 Dec 11;33(4):615-22. Epub 2011 Jan 11.

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11357-010-9202-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220400PMC
December 2011

Runs of homozygosity do not influence survival to old age.

PLoS One 2011 25;6(7):e22580. Epub 2011 Jul 25.

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022580PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143169PMC
December 2011

When grandmothers matter.

Gerontology 2010 2;56(2):214-6. Epub 2009 Nov 2.

Department of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1159/000255170DOI Listing
June 2010

Polymorphisms in TLR4 and TLR2 genes, cytokine production and survival in rural Ghana.

Eur J Hum Genet 2010 Apr 21;18(4):490-5. Epub 2009 Oct 21.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2009.182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987239PMC
April 2010

Genetic variation in pentraxin (PTX) 3 gene associates with PTX3 production and fertility in women.

Biol Reprod 2010 Feb 21;82(2):299-304. Epub 2009 Oct 21.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1095/biolreprod.109.079111DOI Listing
February 2010

Common CFTR gene variants influence body composition and survival in rural Ghana.

Hum Genet 2010 Feb 5;127(2):201-6. Epub 2009 Nov 5.

Department of Gerontology and Geriatrics, Leiden University Medical Center (LUMC), C2-R, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00439-009-0762-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806536PMC
February 2010

Socio-economic status by rapid appraisal is highly correlated with mortality risks in rural Africa.

Trans R Soc Trop Med Hyg 2009 Aug;103(8):795-800

Department of Gerontology and Geriatrics, C-2-R, Leiden University Medical Center, RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.trstmh.2008.12.003DOI Listing
August 2009

VDR gene variants associate with cognitive function and depressive symptoms in old age.

Neurobiol Aging 2009 Mar 21;30(3):466-73. Epub 2007 Aug 21.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S019745800700258
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http://dx.doi.org/10.1016/j.neurobiolaging.2007.07.001DOI Listing
March 2009

Genes encoding longevity: from model organisms to humans.

Aging Cell 2008 Mar 15;7(2):270-80. Epub 2008 Jan 15.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://doi.wiley.com/10.1111/j.1474-9726.2008.00366.x
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http://dx.doi.org/10.1111/j.1474-9726.2008.00366.xDOI Listing
March 2008

SIRT1 gene, age-related diseases, and mortality: the Leiden 85-plus study.

J Gerontol A Biol Sci Med Sci 2007 Sep;62(9):960-5

Department of Gerontology and Geriatrics C2-R, Leiden University Medical Center, PO box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1093/gerona/62.9.960DOI Listing
September 2007

Mental performance in old age dependent on cortisol and genetic variance in the mineralocorticoid and glucocorticoid receptors.

Neuropsychopharmacology 2007 Jun 29;32(6):1295-301. Epub 2006 Nov 29.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/sj.npp.1301260DOI Listing
June 2007

Liver X receptor alpha associates with human life span.

J Gerontol A Biol Sci Med Sci 2007 Apr;62(4):343-9

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/gerona/62.4.343DOI Listing
April 2007

Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age.

Eur J Hum Genet 2007 Mar 24;15(3):294-301. Epub 2007 Jan 24.

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/sj.ejhg.5201766DOI Listing
March 2007

Genetic variants in the glucocorticoid receptor gene (NR3C1) and cardiovascular disease risk. The Leiden 85-plus Study.

Biogerontology 2006 Aug 5;7(4):231-8. Epub 2006 May 5.

Department of Gerontology and Geriatrics C2-R, Leiden University Medical Center (LUMC), PO box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10522-006-9021-2DOI Listing
August 2006

Impact of genetic variations in the WRN gene on age related pathologies and mortality.

Mech Ageing Dev 2006 Mar 6;127(3):307-13. Epub 2006 Jan 6.

Department of Gerontology and Geriatrics C2-R, Leiden University Medical Center (LUMC), P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.mad.2005.11.005DOI Listing
March 2006