Marios Politis

Marios Politis

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Marios Politis

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Imidazoline 2 binding sites reflecting astroglia pathology in Parkinson's disease: an in vivo11C-BU99008 PET study.

Brain 2019 Oct;142(10):3116-3128

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1093/brain/awz260DOI Listing
October 2019

Applications of amyloid, tau, and neuroinflammation PET imaging to Alzheimer's disease and mild cognitive impairment.

Hum Brain Mapp 2019 Sep 14. Epub 2019 Sep 14.

Neurodegeneration Imaging Group (NIG), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London (KCL), London, UK.

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http://dx.doi.org/10.1002/hbm.24782DOI Listing
September 2019

Speech difficulties in early de novo patients with Parkinson's disease.

Parkinsonism Relat Disord 2019 Jul 7;64:256-261. Epub 2019 May 7.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.04.026DOI Listing
July 2019

Dysphagia is associated with presynaptic dopaminergic dysfunction and greater non-motor symptom burden in early drug-naïve Parkinson's patients.

PLoS One 2019 25;14(7):e0214352. Epub 2019 Jul 25.

Neurodegeneration Imaging Group (NIG), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214352PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657830PMC
July 2019

Magnetic resonance imaging in Alzheimer's disease and mild cognitive impairment.

J Neurol 2019 Jun 17;266(6):1293-1302. Epub 2018 Aug 17.

Neurodegeneration Imaging Group (NIG), Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.

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http://dx.doi.org/10.1007/s00415-018-9016-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517561PMC
June 2019

Comparison of phosphodiesterase 10A and dopamine transporter levels as markers of disease burden in early Parkinson's disease.

Mov Disord 2019 Jun 3. Epub 2019 Jun 3.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.27733DOI Listing
June 2019

Molecular Imaging in Huntington's Disease.

Int Rev Neurobiol 2018;142:289-333. Epub 2018 Aug 29.

Neurodegeneration Imaging Group (NIG), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2018.08.007DOI Listing
May 2019

Structural Magnetic Resonance Imaging in Huntington's Disease.

Int Rev Neurobiol 2018;142:335-380. Epub 2018 Oct 8.

Neurodegeneration Imaging Group (NIG), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2018.09.006DOI Listing
May 2019

Preface.

Authors:
Marios Politis

Int Rev Neurobiol 2018 ;142:xi-xii

The Neurodegeneration Imaging Group, King's College London.

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http://dx.doi.org/10.1016/S0074-7742(18)30146-6DOI Listing
May 2019

Imaging Transplantation in Movement Disorders.

Int Rev Neurobiol 2018 3;143:213-263. Epub 2018 Nov 3.

Neurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2018.10.002DOI Listing
May 2019

Preface.

Authors:
Marios Politis

Int Rev Neurobiol 2018 ;143:ix-x

The Neurodegeneration Imaging Group, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1016/S0074-7742(18)30162-4DOI Listing
May 2019

Predicting cognitive decline with non-clinical markers in Parkinson's disease (PRECODE-2).

J Neurol 2019 May 28;266(5):1203-1210. Epub 2019 Feb 28.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), Maurice Wohl Clinical Neuroscience Institute, King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.

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http://dx.doi.org/10.1007/s00415-019-09250-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469665PMC
May 2019

Molecular Imaging of the Dopaminergic System in Idiopathic Parkinson's Disease.

Int Rev Neurobiol 2018 6;141:131-172. Epub 2018 Sep 6.

Neurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2018.08.003DOI Listing
April 2019

Molecular Imaging of the Serotonergic System in Parkinson's Disease.

Int Rev Neurobiol 2018 6;141:173-210. Epub 2018 Sep 6.

Neurodegeneration Imaging Group, Department of Basic & Clinical Neuroscience, King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2018.08.002DOI Listing
April 2019

Advances in MRI Methodology.

Int Rev Neurobiol 2018 14;141:31-76. Epub 2018 Sep 14.

Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2018.08.008DOI Listing
April 2019

Preface.

Authors:
Marios Politis

Int Rev Neurobiol 2018 ;141:xv-xvi

The Neurodegeneration Imaging Group, King's College London.

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http://dx.doi.org/10.1016/S0074-7742(18)30122-3DOI Listing
April 2019

Cortical thinning across Parkinson's disease stages and clinical correlates.

J Neurol Sci 2019 Mar 17;398:31-38. Epub 2019 Jan 17.

Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2019.01.020DOI Listing
March 2019

Dementia spectrum disorders: lessons learnt from decades with PET research.

J Neural Transm (Vienna) 2019 Mar 14;126(3):233-251. Epub 2019 Feb 14.

Neurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.

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http://dx.doi.org/10.1007/s00702-019-01975-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449308PMC
March 2019

The role of phosphodiesterase 4 in excessive daytime sleepiness in Parkinson's disease.

Parkinsonism Relat Disord 2019 Feb 22. Epub 2019 Feb 22.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King's College London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.02.027DOI Listing
February 2019

Neuroimaging in Lewy body dementia.

J Neurol 2019 Jan 14;266(1):1-26. Epub 2018 May 14.

Neurodegeneration Imaging Group (NIG), Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.

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http://dx.doi.org/10.1007/s00415-018-8892-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342883PMC
January 2019

Serotonergic dysregulation is linked to sleep problems in Parkinson's disease.

Neuroimage Clin 2018 2;18:630-637. Epub 2018 Mar 2.

Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.

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http://dx.doi.org/10.1016/j.nicl.2018.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964830PMC
January 2019

Preface.

Authors:
Marios Politis

Int Rev Neurobiol 2019 ;144:xiii

The Neurodegeneration Imaging Group, King's College London.

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http://dx.doi.org/10.1016/S0074-7742(19)30009-1DOI Listing
January 2019

Disease-related patterns of in vivo pathology in Corticobasal syndrome.

Eur J Nucl Med Mol Imaging 2018 12 8;45(13):2413-2425. Epub 2018 Aug 8.

Neurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.

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http://dx.doi.org/10.1007/s00259-018-4104-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208819PMC
December 2018

PDE10A and ADCY5 mutations linked to molecular and microstructural basal ganglia pathology.

Mov Disord 2018 12 21;33(12):1961-1965. Epub 2018 Oct 21.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1002/mds.27523DOI Listing
December 2018

Hybrid PET-MRI Applications in Movement Disorders.

Int Rev Neurobiol 2019 8;144:211-257. Epub 2018 Nov 8.

Department of Basic & Clinical Neuroscience, Neurodegeneration Imaging Group, King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2018.10.003DOI Listing
November 2018

Molecular Imaging of Dementia With Lewy Bodies.

Int Rev Neurobiol 2019 28;144:59-93. Epub 2018 Nov 28.

Neurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2018.10.007DOI Listing
November 2018

Imaging Markers of Progression in Parkinson's Disease.

Mov Disord Clin Pract 2018 Nov-Dec;5(6):586-596. Epub 2018 Oct 9.

Parkinson's Disease Research Clinic, Brain and Mind Centre University of Sydney Sydney NSW Australia.

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http://dx.doi.org/10.1002/mdc3.12673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277366PMC
October 2018

REM behavior disorder predicts motor progression and cognitive decline in Parkinson disease.

Neurology 2018 09 8;91(10):e894-e905. Epub 2018 Aug 8.

From the Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006134DOI Listing
September 2018

Neuroimaging of Sleep Disturbances in Movement Disorders.

Front Neurol 2018 11;9:767. Epub 2018 Sep 11.

Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

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https://www.frontiersin.org/article/10.3389/fneur.2018.00767
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http://dx.doi.org/10.3389/fneur.2018.00767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141751PMC
September 2018

The serotonergic system in Parkinson's patients with dyskinesia: evidence from imaging studies.

J Neural Transm (Vienna) 2018 08 20;125(8):1217-1223. Epub 2017 Dec 20.

Neurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.

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http://dx.doi.org/10.1007/s00702-017-1823-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060863PMC
August 2018

Chronic exposure to dopamine agonists affects the integrity of striatal D receptors in Parkinson's patients.

Neuroimage Clin 2017 24;16:455-460. Epub 2017 Aug 24.

Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1016/j.nicl.2017.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577411PMC
May 2018

Diabetes mellitus and Parkinson disease.

Neurology 2018 05 6;90(19):e1654-e1662. Epub 2018 Apr 6.

From the Neurodegeneration Imaging Group (G.P., S.P., H.W., B.G., F.N., M.P.), Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; and Division of Geriatrics (B.G., N.F.), Department of Translational Medical Sciences, University of Naples Federico II, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000005475DOI Listing
May 2018

Nucleus basalis of Meynert degeneration precedes and predicts cognitive impairment in Parkinson's disease.

Brain 2018 05;141(5):1501-1516

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1093/brain/awy072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171218PMC
May 2018

Imaging the Nonmotor Symptoms in Parkinson's Disease.

Int Rev Neurobiol 2017 7;133:179-257. Epub 2017 Jun 7.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2017.05.001DOI Listing
April 2018

Excessive daytime sleepiness may be associated with caudate denervation in Parkinson disease.

J Neurol Sci 2018 04 21;387:220-227. Epub 2018 Feb 21.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.02.032DOI Listing
April 2018

Imaging in Parkinson's Disease.

Int Rev Neurobiol 2017 30;132:233-274. Epub 2017 Mar 30.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.

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http://dx.doi.org/10.1016/bs.irn.2017.02.015DOI Listing
March 2018

Dopamine reuptake transporter-single-photon emission computed tomography and transcranial sonography as imaging markers of prediagnostic Parkinson's disease.

Mov Disord 2018 03 30;33(3):478-482. Epub 2018 Jan 30.

Department of Clinical Neurosciences, Royal Free Campus, UCL Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1002/mds.27282DOI Listing
March 2018

Increased dopaminergic function in the thalamus is associated with excessive daytime sleepiness.

Sleep Med 2018 03 12;43:25-30. Epub 2017 Dec 12.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2017.11.1137DOI Listing
March 2018

Striatal molecular alterations in HD gene carriers: a systematic review and meta-analysis of PET studies.

J Neurol Neurosurg Psychiatry 2018 02 9;89(2):185-196. Epub 2017 Sep 9.

Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1136/jnnp-2017-316633DOI Listing
February 2018

C-PE2I and F-Dopa PET for assessing progression rate in Parkinson's: A longitudinal study.

Mov Disord 2018 01 30;33(1):117-127. Epub 2017 Oct 30.

Centre for Neurodegeneration and Neuroinflammation, Division of Brain Sciences, Imperial College London, London, UK.

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http://dx.doi.org/10.1002/mds.27183DOI Listing
January 2018

PET Molecular Imaging Research of Levodopa-Induced Dyskinesias in Parkinson's Disease.

Curr Neurol Neurosci Rep 2017 Oct 3;17(11):90. Epub 2017 Oct 3.

Neurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 125 Coldharbour Lane, London, Camberwell, SE5 9NU, UK.

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http://dx.doi.org/10.1007/s11910-017-0794-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626800PMC
October 2017

Loss of phosphodiesterase 4 in Parkinson disease: Relevance to cognitive deficits.

Neurology 2017 Aug 12;89(6):586-593. Epub 2017 Jul 12.

From the Neurodegeneration Imaging Group (F.N., H.W., G.P., M.P.) and Department of Neuroimaging (M.A.M., E.A.R.), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London; Imanova Ltd., Centre for Imaging Sciences (C.C., G.E.S., R.N.G., E.A.R.), and Division of Brain Sciences, Imperial College London (R.N.G), Hammersmith Hospital; and Sobell Department of Motor Neuroscience (T.F.), UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004201DOI Listing
August 2017

PET image reconstruction using multi-parametric anato-functional priors.

Phys Med Biol 2017 Jul 6;62(15):5975-6007. Epub 2017 Jul 6.

Department of Biomedical Engineering, Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, London, United Kingdom.

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http://dx.doi.org/10.1088/1361-6560/aa7670DOI Listing
July 2017

Urinary dysfunction in early de novo patients with Parkinson's disease.

Mov Disord 2017 06 3;32(6):939-940. Epub 2017 Mar 3.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King's College London, London, UK.

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http://dx.doi.org/10.1002/mds.26967DOI Listing
June 2017

Disease progression in LRRK2 parkinsonism.

Authors:
Marios Politis

Lancet Neurol 2017 05;16(5):334-335

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9NU, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30082-0DOI Listing
May 2017

Be vigilant for dementia in Parkinson’s disease.

Practitioner 2017 May;261(1804):11-5

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May 2017

Cognitive decline in Parkinson disease.

Nat Rev Neurol 2017 Apr 3;13(4):217-231. Epub 2017 Mar 3.

KCL-PARCOG group, Institute of Psychiatry, Psychology &Neuroscience, King's College London, De Crespigny Park, London SE5 8AF, UK.

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http://dx.doi.org/10.1038/nrneurol.2017.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643027PMC
April 2017

Parkinson's Disease, Diabetes and Cognitive Impairment.

Recent Pat Endocr Metab Immune Drug Discov 2016 ;10(1):11-21

Neurodegeneration Imaging Group, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), 125 Coldharbour Lane, Camberwell, London, SE5 9NU; UK.

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March 2017

A systematic review of lessons learned from PET molecular imaging research in atypical parkinsonism (Niccolini and Politis, 2016) : Reply to Jean-Claude Baron Letter to Editor.

Authors:
Marios Politis

Eur J Nucl Med Mol Imaging 2017 03;44(3):548-550

Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), Maurice Wohl Clinical Neuroscience Institute IoPPN, King's College London, 125 Coldharbour Lane, London, SE5 9NU, UK.

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http://dx.doi.org/10.1007/s00259-016-3597-9DOI Listing
March 2017

Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients.

Mov Disord 2017 02 17;32(2):235-240. Epub 2016 Nov 17.

Centre for Neurodegeneration and Neuroinflammation, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1002/mds.26848DOI Listing
February 2017

Serotonin transporter in Parkinson's disease: A meta-analysis of positron emission tomography studies.

Ann Neurol 2017 Feb;81(2):171-180

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.24859DOI Listing
February 2017

The psychosis spectrum in Parkinson disease.

Nat Rev Neurol 2017 Feb 20;13(2):81-95. Epub 2017 Jan 20.

KCL-PARCOG group, Institute of Psychiatry, Psychology &Neuroscience, King's College London, De Crespigny Park, London SE5 8AF, UK.

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http://dx.doi.org/10.1038/nrneurol.2016.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656278PMC
February 2017

Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers.

Mov Disord 2017 02 2;32(2):181-192. Epub 2017 Feb 2.

Morton and Gloria Shulman Movement Disorder Unit & E.J. Safra Parkinson Disease Program, Neurology Div/Dept. Medicine, Toronto Western Hospital, UHN; Krembil Research Institute, UHN; Research Imaging Centre, Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/mds.26907DOI Listing
February 2017

Molecular Imaging Markers to Track Huntington's Disease Pathology.

Front Neurol 2017 30;8:11. Epub 2017 Jan 30.

Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, King's College London , London , UK.

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http://dx.doi.org/10.3389/fneur.2017.00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278260PMC
January 2017

A systematic review of lessons learned from PET molecular imaging research in atypical parkinsonism.

Eur J Nucl Med Mol Imaging 2016 Nov 28;43(12):2244-2254. Epub 2016 Jul 28.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.

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http://dx.doi.org/10.1007/s00259-016-3464-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047923PMC
November 2016

Loss of extra-striatal phosphodiesterase 10A expression in early premanifest Huntington's disease gene carriers.

J Neurol Sci 2016 Sep 15;368:243-8. Epub 2016 Jul 15.

Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK; Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2016.07.033DOI Listing
September 2016

Serotonergic loss underlying apathy in Parkinson's disease.

Brain 2016 09;139(Pt 9):2338-9

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.

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http://dx.doi.org/10.1093/brain/aww190DOI Listing
September 2016

Imaging in Parkinson's disease.

Clin Med (Lond) 2016 Aug;16(4):371-5

Neurodegeneration Imaging Group, King's College London, London, UK

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http://dx.doi.org/10.7861/clinmedicine.16-4-371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280219PMC
August 2016

Phosphodiesterase 10A in Schizophrenia: A PET Study Using [(11)C]IMA107.

Am J Psychiatry 2016 07 19;173(7):714-21. Epub 2016 Feb 19.

From the Department of Psychosis Studies, the Neurodegeneration Imaging Group, the Department of Basic and Clinical Neuroscience, and the Department of Neuroimaging, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London; the Division of Brain Sciences, Department of Medicine, and the Psychiatric Imaging Group, Medical Research Council Clinical Sciences Centre, Institute of Clinical Science, Imperial College London, London; and Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London.

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http://dx.doi.org/10.1176/appi.ajp.2015.15040518DOI Listing
July 2016

Cholinergic imaging in dementia spectrum disorders.

Eur J Nucl Med Mol Imaging 2016 Jul 16;43(7):1376-86. Epub 2016 Mar 16.

Neurodegeneration Imaging Group, Department of Basic & Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1007/s00259-016-3349-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865532PMC
July 2016

Aberrant nigral diffusion in Parkinson's disease: A longitudinal diffusion tensor imaging study.

Mov Disord 2016 07 22;31(7):1020-6. Epub 2016 Apr 22.

Neurology Imaging Unit, Hammersmith Hospital, Imperial College London, London, UK.

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http://dx.doi.org/10.1002/mds.26606DOI Listing
July 2016

Current status of PET imaging in Huntington's disease.

Eur J Nucl Med Mol Imaging 2016 Jun 22;43(6):1171-82. Epub 2016 Feb 22.

Neurodegeneration Imaging Group, Department of Basic & Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King's College London, 125 Coldharbour Lane, Camberwell, London, SE5 9NU, UK.

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http://dx.doi.org/10.1007/s00259-016-3324-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844650PMC
June 2016

Serotonin-to-dopamine transporter ratios in Parkinson disease: Relevance for dyskinesias.

Neurology 2016 Mar 26;86(12):1152-8. Epub 2016 Feb 26.

From the Neurology Imaging Unit (A.-A.R., P.P.), Centre of Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Hammersmith Campus, Imperial College London; Neurodegeneration Imaging Group (M.P.), Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London; and Radiological Sciences Unit (D.T.), Imperial College Healthcare NHS Trust, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000002494DOI Listing
March 2016

The X-Linked Hypothesis of Brain Disorders: Can Gender Ratios Tell Us Anything About Cellular Etiology of Neurodegenerative and Psychiatric Diseases?

Neuroscientist 2015 Dec 8;21(6):589-98. Epub 2014 Aug 8.

Department of Psychology, University of New Mexico, Albuquerque, NM, USA.

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http://dx.doi.org/10.1177/1073858414545999DOI Listing
December 2015

Morphometric changes in the reward system of Parkinson's disease patients with impulse control disorders.

J Neurol 2015 Dec 26;262(12):2653-61. Epub 2015 Sep 26.

Division of Brain Sciences, Neurology Imaging Unit, Centre of Neuroinflammation and Neurodegeneration, Hammersmith Campus, Imperial College London, London, UK.

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http://link.springer.com/content/pdf/10.1007%2Fs00415-015-78
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http://dx.doi.org/10.1007/s00415-015-7892-3DOI Listing
December 2015

Increased central microglial activation associated with peripheral cytokine levels in premanifest Huntington's disease gene carriers.

Neurobiol Dis 2015 Nov 18;83:115-21. Epub 2015 Aug 18.

Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2015.08.011DOI Listing
November 2015

Psychogenic and neural visual-cue response in PD dopamine dysregulation syndrome.

Parkinsonism Relat Disord 2015 Nov 25;21(11):1336-41. Epub 2015 Sep 25.

Division of Brain Sciences, Department of Medicine, Hammersmith Hospital, Imperial College London, UK; Neurodegeneration Imaging Group, Department of Clinical Neuroscience, King's College London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2015.09.042DOI Listing
November 2015

Altered PDE10A expression detectable early before symptomatic onset in Huntington's disease.

Brain 2015 Oct 21;138(Pt 10):3016-29. Epub 2015 Jul 21.

1 Neurodegeneration Imaging Group, Department of Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK 2 Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK

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http://dx.doi.org/10.1093/brain/awv214DOI Listing
October 2015

Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease.

Brain 2015 Oct 25;138(Pt 10):3003-15. Epub 2015 Jul 25.

1 Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK 2 Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK

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http://dx.doi.org/10.1093/brain/awv219DOI Listing
October 2015

Recent imaging advances in neurology.

J Neurol 2015 Sep 26;262(9):2182-94. Epub 2015 Mar 26.

Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, SE5 8AF, UK.

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http://dx.doi.org/10.1007/s00415-015-7711-xDOI Listing
September 2015

Molecular imaging of levodopa-induced dyskinesias.

Cell Mol Life Sci 2015 Jun 15;72(11):2107-17. Epub 2015 Feb 15.

Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, SE5 8AF, UK.

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http://dx.doi.org/10.1007/s00018-015-1854-xDOI Listing
June 2015

Single versus multiple impulse control disorders in Parkinson's disease: an ¹¹C-raclopride positron emission tomography study of reward cue-evoked striatal dopamine release.

J Neurol 2015 Jun 18;262(6):1504-14. Epub 2015 Apr 18.

Centre for Neuroinflammation and Neurodegeneration, Imperial College London, Hammersmith Hospital Campus, London, W12 0NN, UK,

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http://dx.doi.org/10.1007/s00415-015-7722-7DOI Listing
June 2015

The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study.

Neurobiol Aging 2015 Apr 6;36(4):1736-1742. Epub 2015 Jan 6.

Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK; Neurodegeneration Imaging Group, Department of Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.037DOI Listing
April 2015

PET in multiple sclerosis.

Clin Nucl Med 2015 Jan;40(1):e46-52

From the *Division of Brain Sciences, Department of Medicine, Hammersmith Hospital, Imperial College London; and †Neurodegeneration Imaging Group, Department of Clinical Neuroscience, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1097/RLU.0000000000000359DOI Listing
January 2015

Serotonin in Parkinson's disease.

Behav Brain Res 2015 Jan 31;277:136-45. Epub 2014 Jul 31.

Neurodegeneration Imaging Group, Department of Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, United Kingdom; Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.bbr.2014.07.037DOI Listing
January 2015

Increased PK11195-PET binding in normal-appearing white matter in clinically isolated syndrome.

Brain 2015 Jan 21;138(Pt 1):110-9. Epub 2014 Nov 21.

1 Centre for Neuroinflammation and Neurodegeneration, Faculty of Medicine, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.

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http://dx.doi.org/10.1093/brain/awu331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383265PMC
January 2015

Dopamine receptor mapping with PET imaging in Parkinson's disease.

J Neurol 2014 Dec 15;261(12):2251-63. Epub 2014 Mar 15.

Neurodegeneration Imaging Group, Department of Clinical Neuroscience, King's College London, London, SE5 8AF, UK.

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http://dx.doi.org/10.1007/s00415-014-7302-2DOI Listing
December 2014

Neuroimaging in Parkinson disease: from research setting to clinical practice.

Authors:
Marios Politis

Nat Rev Neurol 2014 Dec 11;10(12):708-22. Epub 2014 Nov 11.

Neurodegeneration Imaging Group, Department of Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London SE5 8AF, UK.

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http://dx.doi.org/10.1038/nrneurol.2014.205DOI Listing
December 2014

Neuroimaging in Huntington's disease.

World J Radiol 2014 Jun;6(6):301-12

Flavia Niccolini, Marios Politis, Neurodegeneration Imaging Group, Department of Clinical Neuroscience, King's College London, London SE5 8AF, United Kingdom.

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http://dx.doi.org/10.4329/wjr.v6.i6.301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072816PMC
June 2014

Microglia activation in multiple sclerosis black holes predicts outcome in progressive patients: an in vivo [(11)C](R)-PK11195-PET pilot study.

Neurobiol Dis 2014 May 6;65:203-10. Epub 2014 Feb 6.

Centre for Neuroinflammation and Neurodegeneration, Faculty of Medicine, Imperial College London, Hammersmith Campus, Du Cane Road, London W12 0NN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.01.018DOI Listing
May 2014

Problematic Internet use in Parkinson's disease.

Parkinsonism Relat Disord 2014 May 5;20(5):482-7. Epub 2014 Feb 5.

Division of Brain Sciences, Department of Medicine, Hammersmith Hospital, Imperial College London, London W12 0NN, UK.

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http://dx.doi.org/10.1016/j.parkreldis.2014.01.019DOI Listing
May 2014

Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART.

AIDS 2014 Jan;28(1):67-72

aDepartment of Medicine, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Norfolk Place bDepartment of HIV and GU Medicine, Imperial College Healthcare NHS Trust cDivision of Brain Sciences, Imperial College London, Hammersmith Hospital Campus, London, UK.

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http://dx.doi.org/10.1097/01.aids.0000432467.54003.f7DOI Listing
January 2014

In vivo imaging of the integration and function of nigral grafts in clinical trials.

Prog Brain Res 2012 ;200:199-220

Department of Medicine, Hammersmith Hospital, Imperial College London, London, UK.

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http://dx.doi.org/10.1016/B978-0-444-59575-1.00009-0DOI Listing
November 2013

Ambient particulate matter and its potential neurological consequences.

Rev Neurosci 2013 ;24(3):323-35

Imperial College, London, UK.

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http://dx.doi.org/10.1515/revneuro-2013-0001DOI Listing
November 2013

Clinical utility of DaTscan™ (123I-Ioflupane Injection) in the diagnosis of Parkinsonian Syndromes.

Degener Neurol Neuromuscul Dis 2013 27;3:33-39. Epub 2013 Jun 27.

Centre for Neuroinflammation and Neurodegeneration, Imperial College London, London, United Kingdom,

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http://dx.doi.org/10.2147/DNND.S19807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065574PMC
June 2013

Serotonergic loss in motor circuitries correlates with severity of action-postural tremor in PD.

Neurology 2013 May 17;80(20):1850-5. Epub 2013 Apr 17.

Department of Medicine, Division of Brain Sciences, Hammersmith Hospital, Imperial College London, UK.

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http://dx.doi.org/10.1212/WNL.0b013e318292a31dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908354PMC
May 2013

Reduplicative paramnesia: a review.

Psychopathology 2012 31;45(6):337-43. Epub 2012 Jul 31.

Centre for Neuroscience, Division of Experimental Medicine, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, UK.

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http://dx.doi.org/10.1159/000337748DOI Listing
March 2013

Neural response to visual sexual cues in dopamine treatment-linked hypersexuality in Parkinson's disease.

Brain 2013 Feb 31;136(Pt 2):400-11. Epub 2013 Jan 31.

Division of Brain Sciences, Department of Medicine, Hammersmith Hospital, Imperial College London, London W12 0NN, UK.

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http://dx.doi.org/10.1093/brain/aws326DOI Listing
February 2013

Imaging of microglia in patients with neurodegenerative disorders.

Front Pharmacol 2012 29;3:96. Epub 2012 May 29.

Division of Experimental Medicine, Faculty of Medicine, Centre for Neuroscience, Hammersmith Hospital, Imperial College London London, UK.

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http://dx.doi.org/10.3389/fphar.2012.00096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361961PMC
October 2012

Positron emission tomography imaging in neurological disorders.

J Neurol 2012 Sep;259(9):1769-80

Division of Experimental Medicine, Faculty of Medicine, Centre for Neuroscience, Hammersmith Hospital, Imperial College London, Cyclotron Building, London W12 0NN, UK.

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http://dx.doi.org/10.1007/s00415-012-6428-3DOI Listing
September 2012

The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study.

Brain 2012 Aug;135(Pt 8):2449-57

Centre for Neuroscience, Division of Experimental Medicine, Department of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1093/brain/aws157DOI Listing
August 2012

Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts.

Sci Transl Med 2012 Apr;4(128):128ra41

Centre for Neuroscience, Division of Experimental Medicine, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London W12 0NN, UK.

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http://dx.doi.org/10.1126/scitranslmed.3003391DOI Listing
April 2012

Clinical application of stem cell therapy in Parkinson's disease.

BMC Med 2012 Jan 4;10. Epub 2012 Jan 4.

Centre for Neuroscience, Department of Medicine, Imperial College London, Hammersmith Hospital, DuCane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1186/1741-7015-10-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261810PMC
January 2012