Mario F Fraga

Mario F Fraga

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Mario F Fraga

Publications by authors named "Mario F Fraga"

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No genome-wide DNA methylation changes found associated with medium-term reduced graphene oxide exposure in human lung epithelial cells.

Epigenetics 2019 Sep 18:1-11. Epub 2019 Sep 18.

Cancer Epigenetics Laboratory, Instituto de Oncología de Asturias (IUOPA), Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Hospital Universitario Central de Asturias (HUCA), Universidad de Oviedo , Oviedo , Spain.

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http://dx.doi.org/10.1080/15592294.2019.1666650DOI Listing
September 2019

Epigenetics in cancer therapy and nanomedicine.

Clin Epigenetics 2019 May 16;11(1):81. Epub 2019 May 16.

Cancer Epigenetics Laboratory, Institute of Oncology of Asturias (IUOPA), ISPA-FINBA-Hospital Universitario Central de Asturias HUCA, Universidad de Oviedo, Avenida de Roma, 33011, Oviedo, Asturias, Spain.

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http://dx.doi.org/10.1186/s13148-019-0675-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524244PMC
May 2019

Alzheimer's disease DNA methylome of pyramidal layers in frontal cortex: laser-assisted microdissection study.

Epigenomics 2018 11 16;10(11):1365-1382. Epub 2018 Oct 16.

Grupo de Neurociencias y muerte Celular, Facultad de Medicina e instituto de Genética, Universidad Nacional de Colombia, Colombia.

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http://dx.doi.org/10.2217/epi-2017-0160DOI Listing
November 2018

Quantification of Global DNA Methylation Levels by Mass Spectrometry.

Methods Mol Biol 2018 ;1708:49-58

Cancer Epigenetics Laboratory, Institute of Oncology of Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1007/978-1-4939-7481-8_3DOI Listing
July 2018

Epigenome-wide analysis reveals specific DNA hypermethylation of T cells during human hematopoietic differentiation.

Epigenomics 2018 07 5;10(7):903-923. Epub 2018 Apr 5.

Cancer Epigenetics Laboratory, Institute of Oncology of Asturias (IUOPA), HUCA, Universidad de Oviedo, Principado de Asturias, Spain.

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http://dx.doi.org/10.2217/epi-2017-0163DOI Listing
July 2018

Distinct chromatin signatures of DNA hypomethylation in aging and cancer.

Aging Cell 2018 06 5;17(3):e12744. Epub 2018 Mar 5.

Nanomedicine Group, Nanomaterials and Nanotechnology Research Center (CINN-CSIC), Universidad de Oviedo, El Entrego, Asturias, Spain.

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http://dx.doi.org/10.1111/acel.12744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946083PMC
June 2018

TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin.

Nat Commun 2018 04 18;9(1):1548. Epub 2018 Apr 18.

Telomeres and Telomerase Group, Molecular Oncology Program, Melchor Fernández Almagro 3, E-28029, Madrid, Spain.

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http://dx.doi.org/10.1038/s41467-018-03916-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906467PMC
April 2018

SDHC Promoter Methylation, a Novel Pathogenic Mechanism in Parasympathetic Paragangliomas.

J Clin Endocrinol Metab 2018 01;103(1):295-305

Head and Neck Oncology Laboratory, Institute of Sanitary Research of Asturias (ISPA), Hospital Universitario Central de Asturias, Institute of Oncology of Asturias (IUOPA), CIBERONC, Oviedo, Spain.

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http://dx.doi.org/10.1210/jc.2017-01702DOI Listing
January 2018

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes.

Nanotoxicology 2017 Sep 13;11(7):857-870. Epub 2017 Sep 13.

f Nanomaterials and Nanotechnology Research Center (CINN-CSIC) , Universidad de Oviedo, Principado de Asturias , Asturias , Spain.

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http://dx.doi.org/10.1080/17435390.2017.1371350DOI Listing
September 2017

Interindividual epigenetic variability: Sound or noise?

Bioessays 2017 07 7;39(7). Epub 2017 Jun 7.

Nanomaterials and Nanotechnology Research Center (CINN-CSIC), Universidad de Oviedo, Principado de Asturias, Spain.

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http://dx.doi.org/10.1002/bies.201700055DOI Listing
July 2017

Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the "safe harbor" AAVS1 locus.

Stem Cell Res 2017 05 22;21:137-140. Epub 2017 Apr 22.

Josep Carreras Leukemia Research Institute, Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain; Center for Networked Biomedical Research on Cancer (CIBERONC), ISCIII, Madrid, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.scr.2017.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446316PMC
May 2017

Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency.

Stem Cell Reports 2016 10 22;7(4):602-618. Epub 2016 Sep 22.

Josep Carreras Leukemia Research Institute, School of Medicine, University of Barcelona, Casanova 143, 08036 Barcelona, Spain; Department of Biomedicine, School of Medicine, University of Barcelona, 08036 Barcelona, Spain; Instituciò Catalana de Recerca i Estudis Avançats (ICREA), 08036 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063541PMC
October 2016

Longitudinal study of DNA methylation during the first 5 years of life.

J Transl Med 2016 06 3;14(1):160. Epub 2016 Jun 3.

Servicio de Pediatría, Consorcio Hospital General Universitario, Universidad de Valencia, Avda. Tres Cruces s/n, 46014, Valencia, Spain.

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http://dx.doi.org/10.1186/s12967-016-0913-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891837PMC
June 2016

Generation of a human iPSC line from a patient with an optic atrophy 'plus' phenotype due to a mutation in the OPA1 gene.

Stem Cell Res 2016 05 13;16(3):673-6. Epub 2016 Apr 13.

Departamento de Bioquímica, Facultad de Medicina, Universidad Autónoma de Madrid, Spain; Instituto de Investigaciones Biomédicas "Alberto Sols" (UAM-CSIC), Madrid, Spain; Centro de Investigación Biomédica en Red (CIBERER), Madrid, Spain; Instituto de Investigación Hospital 12 de Octubre ("i+12"), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2016.03.011DOI Listing
May 2016

Generation of a human iPSC line from a patient with Leigh syndrome caused by a mutation in the MT-ATP6 gene.

Stem Cell Res 2016 05 18;16(3):766-9. Epub 2016 Apr 18.

Departamento de Bioquímica, Facultad de Medicina, Universidad Autónoma de Madrid, Spain; Instituto de Investigaciones Biomédicas "Alberto Sols", (UAM-CSIC) Madrid, Spain; Centro de Investigación Biomédica en Red (CIBERER), Madrid, Spain; Instituto de Investigación Hospital 12 de Octubre ("i + 12"), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2016.04.012DOI Listing
May 2016

Oncometabolic Nuclear Reprogramming of Cancer Stemness.

Stem Cell Reports 2016 Mar 11;6(3):273-83. Epub 2016 Feb 11.

Institució Catalana d'Estudis i Recerca Avançats (ICREA), 08010 Barcelona, Spain; Computational & Mathematical Biology Research Group, Centre de Recerca Matemàtica (CRM), 08193 Barcelona, Spain; Departament de Matemàtiques, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain; Barcelona Graduate School of Mathematics (BGSMath), 08193 Barcelona, Spain; Centre de Recerca Matemàtica (CRM), Office 29 (C3b/140), Edifici C, Campus de Bellaterra, E-08193 Bellaterra, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788754PMC
March 2016

HERG1A potassium channel is the predominant isoform in head and neck squamous cell carcinomas: evidence for regulation by epigenetic mechanisms.

Sci Rep 2016 Jan 20;6:19666. Epub 2016 Jan 20.

Servicio de Otorrinolaringología, Hospital Universitario Central de Asturias and Instituto Universitario de Oncología del Principado de Asturias, Oviedo, Spain.

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http://dx.doi.org/10.1038/srep19666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726400PMC
January 2016

Generation of a human iPSC line from a patient with Leigh syndrome.

Stem Cell Res 2016 Jan 12;16(1):63-6. Epub 2015 Dec 12.

Departamento de Bioquímica, Instituto de Investigaciones Biomédicas "Alberto Sols", Facultad de Medicina (UAM-CSIC), Spain; Centro de Investigación Biomédica en Red en Enfermedades Raras (CIBERER) Madrid, Spain; Instituto de Investigación Hospital 12 de Octubre ("i+12"), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2015.12.005DOI Listing
January 2016

Generation of a human control iPSC line with a European mitochondrial haplogroup U background.

Stem Cell Res 2016 Jan 15;16(1):88-91. Epub 2015 Dec 15.

Departamento de Bioquímica, Instituto de Investigaciones Biomédicas "Alberto Sols", Facultad de Medicina, (UAM-CSIC) and Centro de Investigación Biomédica en Red en Enfermedades Raras (CIBERER), Madrid, Spain; Instituto de Investigación Hospital 12 de Octubre ("i+12"), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2015.12.010DOI Listing
January 2016

Generation of a human iPSC line from a patient with a defect of intergenomic communication.

Stem Cell Res 2016 Jan 28;16(1):120-3. Epub 2015 Dec 28.

Departamento de Bioquímica, Instituto de Investigaciones Biomédicas "Alberto Sols ", Facultad de Medicina (UAM-CSIC), Spain; Centro de Investigación Biomédica en Red en Enfermedades Raras (CIBERER), Madrid, Spain; Instituto de Investigación Hospital 12 de Octubre ("i + 12"), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2015.12.016DOI Listing
January 2016

Generation of a human iPSC line from a patient with a mitochondrial encephalopathy due to mutations in the GFM1 gene.

Stem Cell Res 2016 Jan 29;16(1):124-7. Epub 2015 Dec 29.

Departamento de Bioquímica, Instituto de Investigaciones Biomédicas "Alberto Sols ", Facultad de Medicina (UAM-CSIC), Spain; Centro de Investigación Biomédica en Red en Enfermedades Raras (CIBERER) Madrid, Spain; Instituto de Investigación Hospital 12 de Octubre ("i + 12"), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2015.12.019DOI Listing
January 2016

Epigenetics of Aging.

Curr Genomics 2015 Dec;16(6):435-40

Cancer Epigenetics Laboratory, Institute of Oncology of Asturias (IUOPA), HUCA, Universidad de Oviedo and Nanomaterials and Nanotechnology Research Center (CINN-CSIC)-Universidad de Oviedo (UO) -Principado de Asturias, Spain.

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http://dx.doi.org/10.2174/1389202916666150817203459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765531PMC
December 2015

Aberrant DNA methylation patterns of spermatozoa in men with unexplained infertility.

Hum Reprod 2015 May 9;30(5):1014-28. Epub 2015 Mar 9.

Cancer Epigenetics Laboratory, Institute of Oncology of Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo 33006, Spain

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http://dx.doi.org/10.1093/humrep/dev053DOI Listing
May 2015

DNA methylation patterns in newborns exposed to tobacco in utero.

J Transl Med 2015 Jan 27;13:25. Epub 2015 Jan 27.

Pediatrics Department, Consorcio Hospital General, University of Valencia, Valencia, Spain.

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http://www.translational-medicine.com/content/13/1/25
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http://dx.doi.org/10.1186/s12967-015-0384-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312439PMC
January 2015

The epigenetic basis of adaptation and responses to environmental change: perspective on human reproduction.

Adv Exp Med Biol 2014 ;753:97-117

Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, C/Dr. Emilio Rodríguez Vigil, s/n., Bloque polivalente A, 4° planta, Oviedo, 33006, Asturias, Spain,

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http://link.springer.com/10.1007/978-1-4939-0820-2_6
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http://dx.doi.org/10.1007/978-1-4939-0820-2_6DOI Listing
November 2014

Epigenetic alterations in endocrine-related cancer.

Endocr Relat Cancer 2014 Aug 4;21(4):R319-30. Epub 2014 Jun 4.

Endocrinology and Nutrition ServiceHospital Universitario Central de Asturias, Av. Julian Clavería s/n, 33006 Oviedo, SpainCancer Epigenetics LaboratoryInstituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006 Oviedo, SpainDepartment of Immunology and OncologyNational Center for Biotechnology, CNB-CSIC, Cantoblanco, Madrid E-28049, SpainEndocrinology and Nutrition ServiceHospital Universitario Central de Asturias, Av. Julian Clavería s/n, 33006 Oviedo, SpainCancer Epigenetics LaboratoryInstituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006 Oviedo, SpainDepartment of Immunology and OncologyNational Center for Biotechnology, CNB-CSIC, Cantoblanco, Madrid E-28049, Spain

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http://dx.doi.org/10.1530/ERC-13-0070DOI Listing
August 2014

Reconstructing the DNA methylation maps of the Neandertal and the Denisovan.

Science 2014 May 17;344(6183):523-7. Epub 2014 Apr 17.

Department of Genetics, Alexander Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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http://dx.doi.org/10.1126/science.1250368DOI Listing
May 2014

Negative neuronal differentiation of human adipose-derived stem cell clones.

Regen Med 2014 May;9(3):279-93

Biochemistry & Cell Therapy Unit, Institute of Bioengineering, University Miguel Hernandez, 03202-Elche, Alicante, Spain.

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http://dx.doi.org/10.2217/rme.14.11DOI Listing
May 2014

Role of BRD4 in hematopoietic differentiation of embryonic stem cells.

Epigenetics 2014 Apr 20;9(4):566-78. Epub 2014 Jan 20.

Cancer Epigenetics Laboratory; Instituto Universitario de Oncología del Principado de Asturias (IUOPA); HUCA; Universidad de Oviedo; Oviedo, Spain; Department of Immunology and Oncology; Centro Nacional de Biotecnología/CNB-CSIC; Cantoblanco; Madrid, Spain.

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http://dx.doi.org/10.4161/epi.27711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121367PMC
April 2014

S-adenosylmethionine levels regulate the schwann cell DNA methylome.

Neuron 2014 Mar;81(5):1024-1039

CIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Bizkaia Technology Park, Derio, 48160 Bizkaia, Spain; IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.01.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960855PMC
March 2014

Aging epigenetics: causes and consequences.

Mol Aspects Med 2013 Jul-Aug;34(4):765-81. Epub 2012 Jul 4.

Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1016/j.mam.2012.06.006DOI Listing
December 2013

DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer.

Cancer Prev Res (Phila) 2013 Jul 21;6(7):656-65. Epub 2013 May 21.

Cancer Epigenetics and Biology Program (PEBC), Catalan Institute of Oncology (ICO-IDIBELL), Barcelona 08908, Spain.

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http://dx.doi.org/10.1158/1940-6207.CAPR-12-0501DOI Listing
July 2013

The role of genetics in the establishment and maintenance of the epigenome.

Cell Mol Life Sci 2013 May 10;70(9):1543-73. Epub 2013 Mar 10.

Cancer Epigenetics Laboratory, Institute of Oncology of Asturias (IUOPA-HUCA), University of Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1007/s00018-013-1296-2DOI Listing
May 2013

DNA methylation epigenotypes in breast cancer molecular subtypes.

Breast Cancer Res 2010 29;12(5):R77. Epub 2010 Sep 29.

BIOMICs Research Group, Centro de Investigacion y Estudios Avanzados ‘Lucio Lascaray’, University of the Basque Country UPV/EHU, Vitoria-Gazteiz, Spain.

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http://dx.doi.org/10.1186/bcr2721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096970PMC
February 2013

Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis.

Arthritis Rheum 2013 Jan;65(1):197-205

Departamento de Medicina Interna, Hospital U. M. Valdecilla-Instituto de Formación e Investigación Marqués de Valdecilla, University of Cantabria, and RETICEF, Santander, Spain.

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http://dx.doi.org/10.1002/art.37753DOI Listing
January 2013

Frequent aberrant expression of the human ether à go-go (hEAG1) potassium channel in head and neck cancer: pathobiological mechanisms and clinical implications.

J Mol Med (Berl) 2012 Oct 31;90(10):1173-84. Epub 2012 Mar 31.

Servicio de Otorrinolaringología, Hospital Universitario Central de Asturias and Instituto Universitario de Oncología del Principado de Asturias, Oviedo, Spain.

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http://dx.doi.org/10.1007/s00109-012-0893-0DOI Listing
October 2012

De novo DNA methyltransferases: oncogenes, tumor suppressors, or both?

Trends Genet 2012 Oct 14;28(10):474-9. Epub 2012 Jun 14.

Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo 33006, Spain.

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http://dx.doi.org/10.1016/j.tig.2012.05.006DOI Listing
October 2012

DNA methylation: a promising landscape for immune system-related diseases.

Trends Genet 2012 Oct 21;28(10):506-14. Epub 2012 Jul 21.

Immunology Department, Hospital Universitario Central de Asturias, Oviedo, Spain.

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http://dx.doi.org/10.1016/j.tig.2012.06.005DOI Listing
October 2012

Global DNA hypomethylation in cancer: review of validated methods and clinical significance.

Clin Chem Lab Med 2012 Oct;50(10):1733-42

Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1515/cclm-2011-0902DOI Listing
October 2012

Hypomethylation of LINE-1, and not centromeric SAT-α, is associated with centromeric instability in head and neck squamous cell carcinoma.

Cell Oncol (Dordr) 2012 Aug 21;35(4):259-67. Epub 2012 Jun 21.

Department of Otolaryngology, Instituto Universitario de Oncología del Principado de Asturias, Hospital Universitario Central de Asturias, Oviedo, Spain.

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http://dx.doi.org/10.1007/s13402-012-0085-5DOI Listing
August 2012

Maintenance of human embryonic stem cells in mesenchymal stem cell-conditioned media augments hematopoietic specification.

Stem Cells Dev 2012 Jun 27;21(9):1549-58. Epub 2011 Oct 27.

Stem Cells, Development, and Cancer Laboratory, GENYO: Centro de Genómica e Investigación Oncológica Pfizer-Universidad de Granada-Junta de Andalucía, Granada, Spain.

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http://dx.doi.org/10.1089/scd.2011.0400DOI Listing
June 2012

Epigenetics of embryonic stem cells.

Adv Exp Med Biol 2012 ;741:231-53

Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Madrid, Spain.

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http://dx.doi.org/10.1007/978-1-4614-2098-9_16DOI Listing
June 2012

Distinct DNA methylomes of newborns and centenarians.

Proc Natl Acad Sci U S A 2012 Jun 11;109(26):10522-7. Epub 2012 Jun 11.

Cancer Epigenetics and Biology Program, Spanish Biomedical Research Centre Network for Epidemiology and Public Health, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, L’Hospitalet, Barcelona, Catalonia 08908, Spain.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1120658109
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http://dx.doi.org/10.1073/pnas.1120658109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387108PMC
June 2012

iPSCs from cancer cells: challenges and opportunities.

Trends Mol Med 2012 May 20;18(5):245-7. Epub 2012 Apr 20.

Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research (GENyO), Avda de la Ilustración 114, 18007, Granada, Spain.

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http://dx.doi.org/10.1016/j.molmed.2012.04.001DOI Listing
May 2012

DNA methylation contributes to the regulation of sclerostin expression in human osteocytes.

J Bone Miner Res 2012 Apr;27(4):926-37

Department of Internal Medicine, Hospital U.M. Valdecilla-IFIMAV, University of Cantabria, RETICEF, Santander, Spain.

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http://doi.wiley.com/10.1002/jbmr.1491
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http://dx.doi.org/10.1002/jbmr.1491DOI Listing
April 2012

Epigenetic code and self-identity.

Adv Exp Med Biol 2012 ;738:236-55

Department of Immunology and Oncology, National Center for Biotechnology, Madrid, Spain.

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http://link.springer.com/10.1007/978-1-4614-1680-7_14
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http://dx.doi.org/10.1007/978-1-4614-1680-7_14DOI Listing
April 2012

Role of DNA methylation in the regulation of the RANKL-OPG system in human bone.

Epigenetics 2012 Jan 1;7(1):83-91. Epub 2012 Jan 1.

Department of Internal Medicine, Hospital U.M. Valdecilla-IFIMAV, University of Cantabria, RETICEF, Santander, Spain.

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http://dx.doi.org/10.4161/epi.7.1.18753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337833PMC
January 2012

Epigenetics and the environment: emerging patterns and implications.

Nat Rev Genet 2012 Jan 4;13(2):97-109. Epub 2012 Jan 4.

Institute of Molecular Genetics (IGMM), CNRS UMR-5535 and University of Montpellier, 1919 route de Mende, 34293 Montpellier, France. cnrs.fr

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http://dx.doi.org/10.1038/nrg3142DOI Listing
January 2012

The effects of the dietary polyphenol resveratrol on human healthy aging and lifespan.

Epigenetics 2011 Jul 1;6(7):870-4. Epub 2011 Jul 1.

Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.4161/epi.6.7.16499DOI Listing
July 2011

Aging genetics and aging.

Aging Dis 2011 Jun 28;2(3):186-95. Epub 2011 Apr 28.

Fundación ASTURCOR, Endocrinology and Nutrition Service, Hospital Universitario Central de Asturias, Av. Julian Clavería s/n, 33006 Oviedo, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295054PMC
June 2011

SirT1 brings stemness closer to cancer and aging.

Aging (Albany NY) 2011 Feb;3(2):162-7

Department of Immunology and Oncology, Centro Nacional Biotecnología/CSIC, Cantoblanco, Madrid, Spain.

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http://www.aging-us.com/article/100272
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082011PMC
http://dx.doi.org/10.18632/aging.100272DOI Listing
February 2011

Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease.

Aging Cell 2010 Dec 21;9(6):947-57. Epub 2010 Oct 21.

Departamento de Bioquímica y Biología Molecular Unidad de Epigenética, Instituto Universitario de Oncología, Universidad de Oviedo, 33006-Oviedo, Spain.

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http://dx.doi.org/10.1111/j.1474-9726.2010.00621.xDOI Listing
December 2010