Publications by authors named "Mario A Eisenberger"

100Publications

Telomere lengths differ significantly between small-cell neuroendocrine prostate carcinoma and adenocarcinoma of the prostate.

Hum Pathol 2020 Jul 7;101:70-79. Epub 2020 May 7.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA.

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July 2020

Progress in the Systemic Management of Advanced Prostate Cancer: The Hormone-Sensitive Paradigm.

J Clin Oncol 2019 11 4;37(32):2957-2960. Epub 2019 Sep 4.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD.

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November 2019

Genomic and clinical characterization of pulmonary-only metastatic prostate cancer: A unique molecular subtype.

Prostate 2019 09 7;79(13):1572-1579. Epub 2019 Aug 7.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland.

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September 2019

Wnt-pathway Activating Mutations Are Associated with Resistance to First-line Abiraterone and Enzalutamide in Castration-resistant Prostate Cancer.

Eur Urol 2020 01 5;77(1):14-21. Epub 2019 Jun 5.

Johns Hopkins Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD, USA; Brady Urological Institute, Johns Hopkins University, Baltimore, MD, USA. Electronic address:

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January 2020

Efficacy of Radium-223 in Bone-metastatic Castration-resistant Prostate Cancer with and Without Homologous Repair Gene Defects.

Eur Urol 2019 08 4;76(2):170-176. Epub 2018 Oct 4.

Johns Hopkins Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD, USA; Brady Urological Institute, Johns Hopkins University, Baltimore, MD, USA. Electronic address:

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August 2019

There Is Now Compelling Evidence to Further Evaluate Lower Doses of Abiraterone Acetate in Men With Metastatic Prostate Cancer: It Should Be Safer, May Be as Effective and Less Expensive.

J Clin Oncol 2018 10 6;36(30):3059-3060. Epub 2018 Sep 6.

Pedro Isaacsson Velho and Mario A. Eisenberger, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD.

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October 2018

Reply to M. Horiguchi et al.

J Clin Oncol 2018 03 26;36(8):826-827. Epub 2018 Jan 26.

Mario A. Eisenberger, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; Wenping Zhang, Sanofi, Bridgewater, NJ; Zhenming Shun, Sanofi, Cambridge, MA; and Johann de Bono, Royal Marsden National Health Service Foundation Trust/The Institute of Cancer Research, Sutton, United Kingdom.

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March 2018

Randomized, Noncomparative, Phase II Trial of Early Switch From Docetaxel to Cabazitaxel or Vice Versa, With Integrated Biomarker Analysis, in Men With Chemotherapy-Naïve, Metastatic, Castration-Resistant Prostate Cancer.

J Clin Oncol 2017 Oct 20;35(28):3181-3188. Epub 2017 Jun 20.

Emmanuel S. Antonarakis and Mario A. Eisenberger, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; Scott T. Tagawa, Giuseppe Galletti, Daniel Worroll, Karla Ballman, Ada Gjyrezi, Shinsuke Tasaki, Luigi Portella, Yang Bai, Brian J. Kirby, David M. Nanus, and Paraskevi Giannakakou, Weill Cornell Medicine/Meyer Cancer Center; Che-Kai Tsao, Mount Sinai Medical Center, New York; Timothy B. Lannin, Shalu Suri, Conor N. Gruber, Erica D. Pratt, and Brian J. Kirby, Cornell University, Ithaca, NY; Marie Vanhuyse, Medical Oncology, Montréal General Hospital; Fred Saad, University of Montreal Hospital Center, Montreal; John Stewart, Atef Zaher, and Wei Zhou, Sanofi, Laval, Quebec, Canada; Guru Sonpavde, University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, AL; Scott North, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada; Costantine Albany, Indiana University School of Medicine, Indianapolis, IN; and Ted Szatrowski, Sanofi, Bridgewater, NJ.

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October 2017

Extreme Response to High-dose Testosterone in BRCA2- and ATM-mutated Prostate Cancer.

Eur Urol 2017 03 29;71(3):499. Epub 2016 Sep 29.

Department of Oncology, Johns Hopkins Medicine, Baltimore, MD, USA. Electronic address:

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March 2017

A Potential Predictive Role for Prostate-specific Antigen Changes at 4 Weeks?

Eur Urol 2016 11 5;70(5):732-733. Epub 2016 Apr 5.

Genitourinary Oncology Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University, Baltimore, MD, USA. Electronic address:

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November 2016

Meta-Analysis Evaluating the Impact of Site of Metastasis on Overall Survival in Men With Castration-Resistant Prostate Cancer.

J Clin Oncol 2016 05 7;34(14):1652-9. Epub 2016 Mar 7.

Susan Halabi, Hua Ma, Nicole C. Solomon, and Andrew J. Armstrong, Duke University, Durham, NC; William Kevin Kelly, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA; Haojin Zhou, Merck, Beijing, China; Karim Fizazi, Institut Gustave Roussy, University of Paris Sud, Villejuif, France; Catherine M. Tangen, Southwest Oncology Group Statistical Center; Mark Rosenthal, Royal Melbourne Hospital, Melbourne, Victoria, Australia; Daniel P. Petrylak, Yale Cancer Center, New Haven, CT; Maha Hussain, University of Michigan, Ann Arbor, MI; Nicholas J. Vogelzang, US Oncology, Las Vegas, NV; Ian M. Thompson, University of Texas at San Antonio, San Antonio; John C. Araujo and Christopher J. Logothetis, The University of Texas MD Anderson Cancer Center, Houston, TX; Kim N. Chi, British Columbia Cancer Agency-Vancouver Cancer Centre, Vancouver, British Columbia; Ian F. Tannock, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada; Johann de Bono, Institute for Cancer Research, Royal Marsden Hospital, Sutton, Surrey, United Kingdom; Mario A. Eisenberger, Johns Hopkins University-School of Medicine, Oncology Center, Baltimore, MD; Abderrahim Fandi and Shaoyi Li, Celgene Corporation, Summit, NJ; David I. Quinn, University of Southern California Norris Cancer Center, Los Angeles; Eric J. Small, University of California San Francisco, San Francisco, CA; Celestia S. Higano, University of Washington, Seattle, WA; and Michael J. Morris, Memorial Sloan-Kettering Cancer Center New York, NY.

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May 2016

Advances in the Treatment of Metastatic Prostate Cancer.

Mayo Clin Proc 2015 Dec;90(12):1719-33

Genito-Urinary Oncology Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University, Baltimore, MD. Electronic address:

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December 2015

Intermittent Androgen Deprivation in Prostate Cancer: Are We Ready to Quit?

J Clin Oncol 2016 Jan 30;34(3):211-4. Epub 2015 Nov 30.

Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD

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January 2016

A Retrospective Analysis of the Effect on Survival of Time from Diagnosis to Neoadjuvant Chemotherapy to Cystectomy for Muscle Invasive Bladder Cancer.

J Urol 2016 Apr 18;195(4 Pt 1):880-5. Epub 2015 Nov 18.

Department of Oncology, Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland; Department of Urology, Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland. Electronic address:

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April 2016

Sarcomatoid Carcinoma of the Prostate: Retrospective Review of a Case Series From the Johns Hopkins Hospital.

Urology 2015 Sep 28;86(3):539-43. Epub 2015 Jun 28.

Division of Medical Oncology, Sidney Kimmel Cancer Center, The Johns Hopkins University, Baltimore, MD. Electronic address:

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September 2015

Initial Evaluation of [(18)F]DCFPyL for Prostate-Specific Membrane Antigen (PSMA)-Targeted PET Imaging of Prostate Cancer.

Mol Imaging Biol 2015 Aug;17(4):565-74

The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Cancer Research Bldg. 2, Room 492, 1550 Orleans St, Baltimore, MD, 21231, USA.

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August 2015

Is there a "Trial Effect" on Outcome of Patients with Metastatic Renal Cell Carcinoma Treated with Sunitinib?

Cancer Res Treat 2016 Jan 5;48(1):281-7. Epub 2015 Mar 5.

Genitourinary Oncology Service, Institute of Oncology, Meir Medical Center, Sackler School of Medicine, Tel Aviv University, Kfar Saba, Israel.

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January 2016

AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer.

N Engl J Med 2014 Sep 3;371(11):1028-38. Epub 2014 Sep 3.

From the Departments of Oncology (E.S.A., H.W., B.L., J.T.I., R.N., C.J.P., S.R.D., M.A.C., M.A.E.), Pathology (H.L.F., T.L.L., Q.Z., A.M.D.M.), and Urology (C.L., M.N., J.C.R., Yan Chen, W.B.I., J.L.), Johns Hopkins University School of Medicine, Baltimore; and Greehey Children's Cancer Research Institute (T.A.M., Yidong Chen) and the Department of Epidemiology and Biostatistics (Yidong Chen), University of Texas Health Science Center at San Antonio, San Antonio.

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September 2014

Small cell carcinoma of the prostate.

Nat Rev Urol 2014 Apr 18;11(4):213-9. Epub 2014 Feb 18.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, Baltimore, MD 21231-1000, USA.

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April 2014

Tolerability and efficacy of docetaxel in older men with metastatic castrate-resistant prostate cancer (mCRPC) in the TAX 327 trial.

J Geriatr Oncol 2014 Apr 2;5(2):119-26. Epub 2014 Jan 2.

Department of Medical Oncology, Princess Margaret Hospital, University Health Network and the University of Toronto, Toronto, Ontario, Canada.

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April 2014

Active smoking may negatively affect response rate, progression-free survival, and overall survival of patients with metastatic renal cell carcinoma treated with sunitinib.

Oncologist 2014 Jan 5;19(1):51-60. Epub 2013 Dec 5.

Genitourinary Oncology Service, Institute of Oncology, Meir Medical Center and the Sackler School of Medicine, Tel Aviv University, Kfar-Saba, Israel; Department of Oncology, Rambam Medical Center, Haifa, Israel; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA; Roswell Park Cancer Institute, Buffalo, New York, USA; Department of Oncology, Wolfson Medical Center, Holon, Israel; Department of Oncology, Asaf Harofe Medical Center, Zerifin, Israel; Department of Oncology, Sheba Medical Center, Tel Hashomer, Israel; Department of Oncology, Soroka University Medical Center, Beer-sheva, Israel.

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January 2014

Management of patients with biochemical recurrence after local therapy for prostate cancer.

Hematol Oncol Clin North Am 2013 Dec 18;27(6):1205-19, viii. Epub 2013 Sep 18.

Prostate Cancer Research Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street, CRB1-1M59, Baltimore, MD 21287, USA.

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December 2013

Determining the optimal treatment for metastatic castration-resistant prostate cancer: age should not be a factor.

Eur Urol 2014 May 16;65(5):884-6. Epub 2013 Oct 16.

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA. Electronic address:

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May 2014

The prognostic importance of metastatic site in men with metastatic castration-resistant prostate cancer.

Eur Urol 2014 Jan 5;65(1):3-6. Epub 2013 Oct 5.

Department of Oncology, McMaster University and Escarpment Cancer Research Institute, Hamilton, Ontario, Canada.

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January 2014

Initial biopsy Gleason score as a predictive marker for survival benefit in patients with castration-resistant prostate cancer treated with docetaxel: data from the TAX327 study.

Eur Urol 2014 Aug 11;66(2):330-6. Epub 2013 Aug 11.

Department of Medical Oncology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands.

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August 2014

The experience with cytotoxic chemotherapy in metastatic castration-resistant prostate cancer.

Urol Clin North Am 2012 Nov;39(4):573-81

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University, Baltimore, MD, USA.

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November 2012

AIM1 promoter hypermethylation as a predictor of decreased risk of recurrence following radical prostatectomy.

Prostate 2012 Jul 29;72(10):1133-9. Epub 2011 Nov 29.

Department of Otolaryngology and Head & Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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July 2012

Biomarkers in the management and treatment of men with metastatic castration-resistant prostate cancer.

Eur Urol 2012 Mar 12;61(3):549-59. Epub 2011 Nov 12.

Duke Cancer Institute and the Duke Prostate Center, Duke University, Durham, NC 27710, USA.

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March 2012

Phase I rapid dose-escalation study of AGS-1C4D4, a human anti-PSCA (prostate stem cell antigen) monoclonal antibody, in patients with castration-resistant prostate cancer: a PCCTC trial.

Cancer Chemother Pharmacol 2012 Mar 22;69(3):763-71. Epub 2011 Oct 22.

Prostate Cancer Research Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, CRB1-1M59, 1650 Orleans Street, Baltimore, MD 21231, USA.

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March 2012

Changes in PSA kinetics predict metastasis- free survival in men with PSA-recurrent prostate cancer treated with nonhormonal agents: combined analysis of 4 phase II trials.

Cancer 2012 Mar;118(6):1533-42

Prostate Cancer Research Program, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, CRB1-1M45, 1650 Orleans Street, Baltimore, MD 21231, USA.

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March 2012

The natural history of metastatic progression in men with prostate-specific antigen recurrence after radical prostatectomy: long-term follow-up.

BJU Int 2012 Jan 20;109(1):32-9. Epub 2011 Jul 20.

Prostate Cancer Research Program, Sidney Kimmel Comprehensive Cancer Center, Brady Urological Institute, Johns Hopkins University, Baltimore, MD 21231, USA.

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January 2012

Contemporary experience with ketoconazole in patients with metastatic castration-resistant prostate cancer: clinical factors associated with PSA response and disease progression.

Prostate 2012 Mar 17;72(4):461-7. Epub 2011 Jun 17.

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

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March 2012

The association between radiographic response and overall survival in men with metastatic castration-resistant prostate cancer receiving chemotherapy.

Cancer 2011 Sep 1;117(17):3963-71. Epub 2011 Mar 1.

Texas Oncology and Department of Medicine, Section of Medical Oncology, Baylor College of Medicine, Houston, Texas, USA.

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September 2011

A phase I study of OSI-461 in combination with mitoxantrone in patients with advanced solid tumors potentially responsive to mitoxantrone.

Cancer Chemother Pharmacol 2011 Feb 6;67(2):431-8. Epub 2010 May 6.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street, CRB1-1M59, Baltimore, MD 21231, USA.

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February 2011

Phase I trial with a combination of docetaxel and ¹⁵³Sm-lexidronam in patients with castration-resistant metastatic prostate cancer.

Urol Oncol 2011 Nov-Dec;29(6):670-5. Epub 2009 Dec 4.

Prostate Cancer Program, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21231, USA.

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March 2012