Mario A Barbosa

Mario A Barbosa

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Mario A Barbosa

Mario A Barbosa

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Osteogenic, anti-osteoclastogenic and immunomodulatory properties of a strontium-releasing hybrid scaffold for bone repair.

Mater Sci Eng C Mater Biol Appl 2019 Jun 16;99:1289-1303. Epub 2019 Feb 16.

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200 - 135 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen, 208, 4200 - 135 Porto, Portugal; ISEP - Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida 431, 4249-015, Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.msec.2019.02.053DOI Listing
June 2019

3D chitosan scaffolds impair NLRP3 inflammasome response in macrophages.

Acta Biomater 2019 Jun 17;91:123-134. Epub 2019 Apr 17.

i3S - Instituto de Inovação e Investigação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-125 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Rua Alfredo Allen, 208, 4200-125 Porto, Portugal; ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S17427061193027
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http://dx.doi.org/10.1016/j.actbio.2019.04.035DOI Listing
June 2019

Comparable Decellularization of Fetal and Adult Cardiac Tissue Explants as 3D-like Platforms for In Vitro Studies.

J Vis Exp 2019 Mar 21(145). Epub 2019 Mar 21.

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto; INEB - Instituto de Engenharia Biomédica, Universidade do Porto; Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto;

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http://dx.doi.org/10.3791/56924DOI Listing
March 2019

The inflammasome in host response to biomaterials: Bridging inflammation and tissue regeneration.

Acta Biomater 2019 Jan 29;83:1-12. Epub 2018 Sep 29.

i3S - Instituto de Inovação e Investigação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-125 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Rua Alfredo Allen, 208, 4200-125 Porto, Portugal; ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S17427061183058
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http://dx.doi.org/10.1016/j.actbio.2018.09.056DOI Listing
January 2019

Fibroblast growth factor improves the motility of human mesenchymal stem cells expanded in a human plasma-derived xeno-free medium through αVβ3 integrin.

J Tissue Eng Regen Med 2019 Jan 3;13(1):36-45. Epub 2018 Dec 3.

i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.

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http://doi.wiley.com/10.1002/term.2766
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http://dx.doi.org/10.1002/term.2766DOI Listing
January 2019

Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning.

Front Immunol 2018 4;9:2837. Epub 2018 Dec 4.

Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.3389/fimmu.2018.02837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288292PMC
December 2018

Extracellular vesicles: intelligent delivery strategies for therapeutic applications.

J Control Release 2018 Nov 24;289:56-69. Epub 2018 Sep 24.

i3S - Instituto de Investigação e Inovação em Saúde da Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2018.09.019DOI Listing
November 2018

The inflammatory response in the regression of lumbar disc herniation.

Arthritis Res Ther 2018 11 6;20(1):251. Epub 2018 Nov 6.

i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen 208, 4200-135, Porto, Portugal.

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https://arthritis-research.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s13075-018-1743-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235196PMC
November 2018

Chitosan porous 3D scaffolds embedded with resolvin D1 to improve in vivo bone healing.

J Biomed Mater Res A 2018 06 3;106(6):1626-1633. Epub 2018 Mar 3.

i3S - Instituto de Inovação e Investigação em Saúde, Universidade do Porto, Porto 4200-125, Portugal.

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http://dx.doi.org/10.1002/jbm.a.36370DOI Listing
June 2018

Profiling the circulating miRnome reveals a temporal regulation of the bone injury response.

Theranostics 2018 24;8(14):3902-3917. Epub 2018 Jun 24.

i3S - Instituto de Investigação e Inovação em Saúde, INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal.

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http://www.thno.org/v08p3902.htm
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http://dx.doi.org/10.7150/thno.24444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071520PMC
June 2018

Age-Correlated Phenotypic Alterations in Cells Isolated From Human Degenerated Intervertebral Discs With Contained Hernias.

Spine (Phila Pa 1976) 2018 03;43(5):E274-E284

Institute for Research and Innovation in Health Sciences (i3S), University of Porto, Porto, Portugal.

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http://dx.doi.org/10.1097/BRS.0000000000002311DOI Listing
March 2018

A co-culture system with three different primary human cell populations reveals that biomaterials and MSC modulate macrophage-driven fibroblast recruitment.

J Tissue Eng Regen Med 2018 Mar 26;12(3):e1433-e1440. Epub 2017 Nov 26.

i3S-Instituto de Investigação e Inovação em Saúde da Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1002/term.2560DOI Listing
March 2018

Pro-inflammatory chitosan/poly(γ-glutamic acid) nanoparticles modulate human antigen-presenting cells phenotype and revert their pro-invasive capacity.

Acta Biomater 2017 11 14;63:96-109. Epub 2017 Sep 14.

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal; Departamento de Patologia e Oncologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S17427061173057
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http://dx.doi.org/10.1016/j.actbio.2017.09.016DOI Listing
November 2017

Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers - pre-clinical and clinical investigations.

J Neuroinflammation 2017 Sep 4;14(1):179. Epub 2017 Sep 4.

i3S-Instituto de Investigação e Inovação em Saúde, University of Porto, Rua Alfredo Allen 208, 4200-135, Porto, Portugal.

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http://dx.doi.org/10.1186/s12974-017-0938-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584030PMC
September 2017

Injectable hybrid system for strontium local delivery promotes bone regeneration in a rat critical-sized defect model.

Sci Rep 2017 07 11;7(1):5098. Epub 2017 Jul 11.

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200 - 135, Porto, Portugal.

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http://dx.doi.org/10.1038/s41598-017-04866-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506032PMC
July 2017

Joint analysis of IVD herniation and degeneration by rat caudal needle puncture model.

J Orthop Res 2017 02 23;35(2):258-268. Epub 2016 Nov 23.

Instituto de Investigação e Inovação em Saúde (i3S), Rua Alfredo Allen 208, 4200-135, Porto, Portugal.

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http://dx.doi.org/10.1002/jor.23114DOI Listing
February 2017

Nanostructured lipid carriers loaded with resveratrol modulate human dendritic cells.

Int J Nanomedicine 2016 28;11:3501-16. Epub 2016 Jul 28.

Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Portugal.

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http://dx.doi.org/10.2147/IJN.S108694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970450PMC
February 2017

Extracellular Vesicles: Immunomodulatory messengers in the context of tissue repair/regeneration.

Eur J Pharm Sci 2017 Feb 17;98:86-95. Epub 2016 Sep 17.

i3S - Instituto de Investigação e Inovação em Saúde, University of Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, University of Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2016.09.017DOI Listing
February 2017

Adsorbed Fibrinogen stimulates TLR-4 on monocytes and induces BMP-2 expression.

Acta Biomater 2017 02 14;49:296-305. Epub 2016 Nov 14.

i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; INEB-Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre 823, 4150-180-Porto, Portugal; ICBAS-Instituto Ciências Biomédicas Abel Salazar da Universidade do Porto, Largo Prof. Abel Salazar, 2, 4099-003 Porto, Portugal.

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http://dx.doi.org/10.1016/j.actbio.2016.11.034DOI Listing
February 2017

Stiffness of polyelectrolyte multilayer film influences endothelial function of endothelial cell monolayer.

Colloids Surf B Biointerfaces 2017 Jan 9;149:379-387. Epub 2016 Nov 9.

MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China. Electronic address:

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http://dx.doi.org/10.1016/j.colsurfb.2016.11.012DOI Listing
January 2017

Poly(γ-glutamic acid) and poly(γ-glutamic acid)-based nanocomplexes enhance type II collagen production in intervertebral disc.

J Mater Sci Mater Med 2017 Jan 24;28(1). Epub 2016 Nov 24.

Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, Porto, 4200-135, Portugal.

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http://dx.doi.org/10.1007/s10856-016-5787-1DOI Listing
January 2017

Fibrinogen scaffolds with immunomodulatory properties promote in vivo bone regeneration.

Biomaterials 2016 12 4;111:163-178. Epub 2016 Oct 4.

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; ICBAS-Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2016.10.004DOI Listing
December 2016

Anti-inflammatory Chitosan/Poly-γ-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc.

Acta Biomater 2016 09 15;42:168-179. Epub 2016 Jun 15.

Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal; ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2016.06.013DOI Listing
September 2016

Macrophage interactions with polylactic acid and chitosan scaffolds lead to improved recruitment of human mesenchymal stem/stromal cells: a comprehensive study with different immune cells.

J R Soc Interface 2016 09;13(122)

i3S-Instituto de Investigação e Inovação em Saúde da Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal INEB-Instituto de Engenharia Biomédica, Porto, Portugal Department of Medical Sciences and Institute for Biomedicine-iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal

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http://rsif.royalsocietypublishing.org/lookup/doi/10.1098/rs
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046958PMC
http://dx.doi.org/10.1098/rsif.2016.0570DOI Listing
September 2016

Circulating extracellular vesicles: Their role in tissue repair and regeneration.

Transfus Apher Sci 2016 Aug 18;55(1):53-61. Epub 2016 Jul 18.

i3S - Instituto de Investigação e Inovação em Saúde, INEB - Instituto de Engenharia Biomédica, University of Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.transci.2016.07.015DOI Listing
August 2016

The two faces of metal ions: From implants rejection to tissue repair/regeneration.

Biomaterials 2016 Apr 25;84:262-275. Epub 2016 Jan 25.

Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; ICBAS - Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2016.01.046DOI Listing
April 2016

NAP-2 Secreted by Human NK Cells Can Stimulate Mesenchymal Stem/Stromal Cell Recruitment.

Stem Cell Reports 2016 Apr 24;6(4):466-473. Epub 2016 Mar 24.

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.

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http://dx.doi.org/10.1016/j.stemcr.2016.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834048PMC
April 2016

Ibuprofen-loaded poly(trimethylene carbonate-co-ε-caprolactone) electrospun fibres for nerve regeneration.

J Tissue Eng Regen Med 2016 Mar 16;10(3):E154-66. Epub 2013 Aug 16.

INEB - Instituto de Engenharia Biomédica, NEWTherapies Group, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1002/term.1792DOI Listing
March 2016

Strontium-rich injectable hybrid system for bone regeneration.

Mater Sci Eng C Mater Biol Appl 2016 Feb 23;59:818-827. Epub 2015 Oct 23.

Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal; ISEP - Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal.

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http://dx.doi.org/10.1016/j.msec.2015.10.038DOI Listing
February 2016

Self-Healing Spongy Coating for Drug "Cocktail" Delivery.

ACS Appl Mater Interfaces 2016 Feb 9;8(7):4309-13. Epub 2016 Feb 9.

MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University , Hangzhou 310027, China.

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http://dx.doi.org/10.1021/acsami.5b11602DOI Listing
February 2016

Development of an immunomodulatory biomaterial: using resolvin D1 to modulate inflammation.

Biomaterials 2015 23;53:566-73. Epub 2015 Mar 23.

ICBAS - Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira n.° 228, 4050-313 Porto, Portugal; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.02.120DOI Listing
January 2016

A Degenerative/Proinflammatory Intervertebral Disc Organ Culture: An Ex Vivo Model for Anti-inflammatory Drug and Cell Therapy.

Tissue Eng Part C Methods 2016 Jan 13;22(1):8-19. Epub 2015 Nov 13.

1 Institute of Orthopaedic Research and Biomechanics, Center for Musculoskeletal Research, University of Ulm , Ulm, Germany .

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http://dx.doi.org/10.1089/ten.tec.2015.0195DOI Listing
January 2016

Effect of Polyelectrolyte Film Stiffness on Endothelial Cells During Endothelial-to-Mesenchymal Transition.

Biomacromolecules 2015 Nov 23;16(11):3584-93. Epub 2015 Oct 23.

MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University , Hangzhou 310027, China.

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http://pubs.acs.org/doi/10.1021/acs.biomac.5b01057
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http://dx.doi.org/10.1021/acs.biomac.5b01057DOI Listing
November 2015

An interferon-γ-delivery system based on chitosan/poly(γ-glutamic acid) polyelectrolyte complexes modulates macrophage-derived stimulation of cancer cell invasion in vitro.

Acta Biomater 2015 Sep 23;23:157-171. Epub 2015 May 23.

I(3)S-Instituto de Investigação e Inovação em Saúde, Universidade doPorto, Porto, Portugal; INEB-Institute of Biomedical Engineering, University of Porto, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal; Department of Pathology and Oncology, Faculty of Medicine, University of Porto, Al. Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.

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http://dx.doi.org/10.1016/j.actbio.2015.05.022DOI Listing
September 2015

Improvement of Bovine Nucleus Pulposus Cells Isolation Leads to Identification of Three Phenotypically Distinct Cell Subpopulations.

Tissue Eng Part A 2015 Aug 14;21(15-16):2216-27. Epub 2015 Jul 14.

1 Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto , Porto, Portugal .

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http://dx.doi.org/10.1089/ten.TEA.2014.0461DOI Listing
August 2015

Poly(γ-Glutamic Acid) as an Exogenous Promoter of Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells.

Tissue Eng Part A 2015 Jun 30;21(11-12):1869-85. Epub 2015 Apr 30.

8REPAIR Lab, Institute of Pathology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

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http://dx.doi.org/10.1089/ten.TEA.2014.0386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449718PMC
June 2015

Neonatal human dermal fibroblasts immobilized in RGD-alginate induce angiogenesis.

Cell Transplant 2014 17;23(8):945-57. Epub 2013 Jul 17.

INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.3727/096368913X670183DOI Listing
May 2015

Finding and tracing human MSC in 3D microenvironments with the photoconvertible protein Dendra2.

Sci Rep 2015 May 14;5:10079. Epub 2015 May 14.

1] Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal [2] INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1038/srep10079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431349PMC
May 2015

Inflammation in intervertebral disc degeneration and regeneration.

J R Soc Interface 2015 Mar;12(104):20141191

Instituto de Engenharia Biomédica-INEB, Universidade do Porto, Porto, Portugal Instituto de Ciências Biomédicas Abel Salazar-ICBAS, Universidade do Porto, Porto, Portugal

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http://dx.doi.org/10.1098/rsif.2014.1191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345483PMC
March 2015

Modulation of the inflammatory response to chitosan through M2 macrophage polarization using pro-resolution mediators.

Biomaterials 2015 Jan 22;37:116-23. Epub 2014 Oct 22.

ICBAS - Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira n.° 228, 4050-313 Porto, Portugal; INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.10.035DOI Listing
January 2015

Kinetics and isotherm of fibronectin adsorption to three-dimensional porous chitosan scaffolds explored by ¹²⁵I-radiolabelling.

Biomatter 2013 Apr-Jun;3(2). Epub 2013 Apr 29.

INEB-Instituto de Engenharia Biomédica; Universidade do Porto; Porto, Portugal; Universidade do Porto; Instituto de Ciências Biomédicas Abel Salazar and Faculdade de Engenharia; Porto, Portugal.

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http://dx.doi.org/10.4161/biom.24791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749804PMC
December 2014

The effect of hyaluronan-based delivery of stromal cell-derived factor-1 on the recruitment of MSCs in degenerating intervertebral discs.

Biomaterials 2014 Sep 24;35(28):8144-53. Epub 2014 Jun 24.

AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.06.017DOI Listing
September 2014

Selective albumin-binding surfaces modified with a thrombin-inhibiting peptide.

Acta Biomater 2014 Mar 5;10(3):1227-37. Epub 2013 Dec 5.

INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal; Universidade do Porto, Instituto de Ciências Biomédicas Abel Salazar, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2013.11.023DOI Listing
March 2014

Impact of 3-D printed PLA- and chitosan-based scaffolds on human monocyte/macrophage responses: unraveling the effect of 3-D structures on inflammation.

Acta Biomater 2014 Feb 5;10(2):613-22. Epub 2013 Nov 5.

IBEC - Institute for Bioengineering of Catalonia, Biomaterials for Regenerative Group, Baldiri Reixac 15-21, 08028 Barcelona, Spain; CIBER in Bioengineering, Biomaterials and Nanomedicine, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2013.10.035DOI Listing
February 2014

Adsorbed fibrinogen enhances production of bone- and angiogenic-related factors by monocytes/macrophages.

Tissue Eng Part A 2014 Jan 14;20(1-2):250-63. Epub 2013 Nov 14.

1 INEB-Instituto de Engenharia Biomédica, Universidade do Porto , Porto, Portugal .

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http://dx.doi.org/10.1089/ten.TEA.2012.0439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875152PMC
January 2014

Macrophage polarization following chitosan implantation.

Biomaterials 2013 Dec 25;34(38):9952-9. Epub 2013 Sep 25.

INEB - Instituto de Engenharia Biomédica, NEWTherapies Group, Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2013.09.012DOI Listing
December 2013

Modulation of stability and mucoadhesive properties of chitosan microspheres for therapeutic gastric application.

Int J Pharm 2013 Sep 11;454(1):116-24. Epub 2013 Jul 11.

INEB - Instituto de Engenharia Biomédica, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.ijpharm.2013.06.068DOI Listing
September 2013

The effect of octadecyl chain immobilization on the hemocompatibility of poly (2-hydroxyethyl methacrylate).

Biomaterials 2012 Nov 26;33(31):7677-85. Epub 2012 Jul 26.

Max Bergmann Center of Biomaterials Dresden, Leibniz Institute of Polymer Research Dresden, Dresden, Germany.

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http://dx.doi.org/10.1016/j.biomaterials.2012.07.007DOI Listing
November 2012

Chitosan drives anti-inflammatory macrophage polarisation and pro-inflammatory dendritic cell stimulation.

Eur Cell Mater 2012 Jul 24;24:136-52; discussion 152-3. Epub 2012 Jul 24.

Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal.

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http://www.ecmjournal.org/journal/papers/vol024/pdf/v024a10.
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July 2012

Mesenchymal stem cell recruitment by stromal derived factor-1-delivery systems based on chitosan/poly(γ-glutamic acid) polyelectrolyte complexes.

Eur Cell Mater 2012 Apr 10;23:249-60; discussion 260-1. Epub 2012 Apr 10.

INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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April 2012

Enhanced mesenchymal stromal cell recruitment via natural killer cells by incorporation of inflammatory signals in biomaterials.

J R Soc Interface 2012 Feb 13;9(67):261-71. Epub 2011 Jul 13.

INEB-Instituto de Engenharia Biomédica, Biomaterials Division, NEWTherapies Group, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1098/rsif.2011.0357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243397PMC
February 2012

Protein adsorption characterization.

Methods Mol Biol 2012 ;811:141-61

Divisão de Biomateriais, INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1007/978-1-61779-388-2_10DOI Listing
February 2012

Layer-by-layer self-assembly of chitosan and poly(γ-glutamic acid) into polyelectrolyte complexes.

Biomacromolecules 2011 Dec 8;12(12):4183-95. Epub 2011 Nov 8.

INEB-Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1021/bm2008235DOI Listing
December 2011

Injectable in situ crosslinkable RGD-modified alginate matrix for endothelial cells delivery.

Biomaterials 2011 Nov 23;32(31):7897-904. Epub 2011 Jul 23.

INEB - Instituto de Engenharia Biomédica, Rua do Campo Alegre, n° 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2011.07.013DOI Listing
November 2011

Phenotypic and proliferative modulation of human mesenchymal stem cells via crosstalk with endothelial cells.

Stem Cell Res 2011 Nov 12;7(3):186-97. Epub 2011 Jun 12.

INEB - Instituto de Engenharia Biomédica, Porto, Portugal; FEUP - Faculdade de Engenharia, Universidade do Porto, Portugal.

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http://dx.doi.org/10.1016/j.scr.2011.05.006DOI Listing
November 2011

Platelet and leukocyte adhesion to albumin binding self-assembled monolayers.

J Mater Sci Mater Med 2011 Sep 14;22(9):2053-63. Epub 2011 Jul 14.

INEB-Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1007/s10856-011-4381-9DOI Listing
September 2011

Interactions of leukocytes and platelets with poly(lysine/leucine) immobilized on tetraethylene glycol-terminated self-assembled monolayers.

Acta Biomater 2011 May 13;7(5):1949-55. Epub 2011 Jan 13.

Instituto de Engenharia Biomédica, Divisão de Biomateriais, Universidade do Porto, Rua do Campo Alegre, Portugal.

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http://dx.doi.org/10.1016/j.actbio.2011.01.013DOI Listing
May 2011

The stability of self-assembled monolayers with time and under biological conditions.

J Biomed Mater Res A 2010 Sep;94(3):833-43

Divisão de Biomateriais, INEB-Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1002/jbm.a.32746DOI Listing
September 2010

Immobilization of human mesenchymal stem cells within RGD-grafted alginate microspheres and assessment of their angiogenic potential.

Biomacromolecules 2010 Aug;11(8):1956-64

INEB-Instituto de Engenharia Biomedica, Rua do Campo Alegre No. 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1021/bm100264aDOI Listing
August 2010

Characterization of polymeric solutions as injectable vehicles for hydroxyapatite microspheres.

AAPS PharmSciTech 2010 Jun 19;11(2):852-8. Epub 2010 May 19.

Dep. de Eng. Mecânica e Gestão Industrial, Escola Superior de Tecnologia e Gestão de Viseu, Campus Politécnico de Repeses, 3504-510, Viseu, Portugal.

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http://dx.doi.org/10.1208/s12249-010-9447-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902341PMC
June 2010

Targeted gene delivery into peripheral sensorial neurons mediated by self-assembled vectors composed of poly(ethylene imine) and tetanus toxin fragment c.

J Control Release 2010 May 20;143(3):350-8. Epub 2010 Jan 20.

INEB-Instituto de Engenharia Biomédica, Divisão de Biomateriais, Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.jconrel.2010.01.018DOI Listing
May 2010

The effect of immobilization of thrombin inhibitors onto self-assembled monolayers on the adsorption and activity of thrombin.

Biomaterials 2010 May 11;31(14):3772-80. Epub 2010 Feb 11.

INEB-Instituto de Engenharia Biomédica, Divisão de Biomateriais, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2010.01.097DOI Listing
May 2010

Adhesion of human leukocytes on mixtures of hydroxyl- and methyl-terminated self-assembled monolayers: effect of blood protein adsorption.

J Biomed Mater Res A 2010 Apr;93(1):12-9

Divisão de Biomateriais, INEB-Instituto de Engenharia Biomédica, Universidade do Porto, Porto 4150-180, Portugal.

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http://dx.doi.org/10.1002/jbm.a.32480DOI Listing
April 2010

Evaluation of the effect of the degree of acetylation on the inflammatory response to 3D porous chitosan scaffolds.

J Biomed Mater Res A 2010 Apr;93(1):20-8

Divisão de Biomateriais, Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1002/jbm.a.32499DOI Listing
April 2010

Induction of notch signaling by immobilization of jagged-1 on self-assembled monolayers.

Biomaterials 2009 Dec 23;30(36):6879-87. Epub 2009 Sep 23.

INEB, Biomaterials Division, NEWTherapies Group, R. Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2009.09.010DOI Listing
December 2009

Protein adsorption and clotting time of pHEMA hydrogels modified with C18 ligands to adsorb albumin selectively and reversibly.

Biomaterials 2009 Oct;30(29):5541-51

INEB-Instituto de Engenharia Biomédica, Divisão de Biomateriais, Universidade do Porto, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2009.06.025DOI Listing
October 2009

Fibronectin-mediated endothelialisation of chitosan porous matrices.

Biomaterials 2009 Oct 16;30(29):5465-75. Epub 2009 Jul 16.

INEB-Instituto de Engenharia Biomédica, Divisão de Biomateriais, Universidade do Porto, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2009.06.056DOI Listing
October 2009

Selective protein adsorption modulates platelet adhesion and activation to oligo(ethylene glycol)-terminated self-assembled monolayers with C18 ligands.

J Biomed Mater Res A 2009 Jun;89(3):642-53

INEB-Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre, Portugal.

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http://dx.doi.org/10.1002/jbm.a.32011DOI Listing
June 2009

Engineering endochondral bone: in vitro studies.

Tissue Eng Part A 2009 Mar;15(3):625-34

Department of Mechanical Engineering, ESTV-Escola Superior de Tecnologia de Viseu, Viseu, Portugal.

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http://dx.doi.org/10.1089/ten.tea.2008.0051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744199PMC
March 2009

Engineering endochondral bone: in vivo studies.

Tissue Eng Part A 2009 Mar;15(3):635-43

Department of Mechanical Engineering, ESTV-Escola Superior de Tecnologia de Viseu, Viseu, Portugal.

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http://dx.doi.org/10.1089/ten.tea.2008.0052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751848PMC
March 2009

Molecularly designed surfaces for blood deheparinization using an immobilized heparin-binding peptide.

J Biomed Mater Res A 2009 Jan;88(1):162-73

Instituto de Engenharia Biomédica, Divisão de Biomateriais, Universidade do Porto, Rua do Campo Alegre, 823, 4150-180, Porto, Portugal.

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http://dx.doi.org/10.1002/jbm.a.31849DOI Listing
January 2009

The correlation between the adsorption of adhesive proteins and cell behaviour on hydroxyl-methyl mixed self-assembled monolayers.

Biomaterials 2009 Jan 25;30(3):307-16. Epub 2008 Oct 25.

INEB - Instituto de Engenharia Biomédica, Divisão de Biomateriais, Universidade do Porto, R. Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2008.09.048DOI Listing
January 2009

Injectability of a bone filler system based on hydroxyapatite microspheres and a vehicle with in situ gel-forming ability.

J Biomed Mater Res B Appl Biomater 2008 Oct;87(1):49-58

Escola Superior de Tecnologia de Viseu (ESTV), Dep. de Eng. Mecânica e Gestão Industrial, 3504-510 Viseu, Portugal.

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http://dx.doi.org/10.1002/jbm.b.31066DOI Listing
October 2008

Fibrinogen adsorption, platelet adhesion and activation on mixed hydroxyl-/methyl-terminated self-assembled monolayers.

Biomaterials 2006 Nov 13;27(31):5357-67. Epub 2006 Jul 13.

INEB - Instituto de Engenharia Biomédica, Laboratório de Biomateriais, Universidade do Porto, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2006.06.010DOI Listing
November 2006

The influence of functional groups of self-assembled monolayers on fibrous capsule formation and cell recruitment.

J Biomed Mater Res A 2006 Mar;76(4):737-43

INEB-Instituto de Engenharia Biomédica, Laboratório de Biomateriais, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1002/jbm.a.30602DOI Listing
March 2006

The attraction of Mac-1+ phagocytes during acute inflammation by methyl-coated self-assembled monolayers.

Biomaterials 2005 Jun;26(16):3021-7

INEB-Instituto de Engenharia Biomédica, Laboratório de Biomateriais, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2004.09.002DOI Listing
June 2005

Protein adsorption on 18-alkyl chains immobilized on hydroxyl-terminated self-assembled monolayers.

Biomaterials 2005 Jun;26(18):3891-99

INEB-Instituto de Engenharia Biomedica, Laboratório de Biomateriais, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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June 2005

Adsorption of a therapeutic enzyme to self-assembled monolayers: effect of surface chemistry and solution pH on the amount and activity of adsorbed enzyme.

Biomaterials 2005 May;26(15):2695-704

INEB - Instituto de Engenharia Biomédica, Laboratório de Biomateriais, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.biomaterials.2004.07.033DOI Listing
May 2005

Proliferation, activity, and osteogenic differentiation of bone marrow stromal cells cultured on calcium titanium phosphate microspheres.

J Biomed Mater Res A 2005 Jan;72(1):57-66

INEB-Instituto de Engenharia Biomédica, Laboratório de Biomateriais, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1002/jbm.a.30217DOI Listing
January 2005

Inflammatory cell recruitment and adhesion to methyl-terminated self-assembled monolayers: effect of implantation time.

Microsc Res Tech 2005 Jan;66(1):37-42

INEB-Instituto de Engenharia Biomédica, Laboratório de Biomateriais, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1002/jemt.20141DOI Listing
January 2005

Inflammatory responses and cell adhesion to self-assembled monolayers of alkanethiolates on gold.

Biomaterials 2004 Jun;25(13):2557-63

Laboratório de Biomaterials (INEB), Instituto de Engenharia Biomédica, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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June 2004

Biocompatibility of chemoenzymatically derived dextran-acrylate hydrogels.

J Biomed Mater Res A 2004 Mar;68(3):584-96

Departamento de Engenharia Química, Universidade de Coimbra, Pinhal de Marrocos, 3030-290 Coimbra, Portugal.

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http://dx.doi.org/10.1002/jbm.a.20102DOI Listing
March 2004

Albumin adsorption on cibacron blue F3G-A immobilized onto oligo(ethylene glycol)-terminated self-assembled monolayers.

J Mater Sci Mater Med 2003 Nov;14(11):945-54

INEB - Instituto de Engenharia Biomédica, Laboratório de Biomateriais, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

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November 2003

Protein adsorption on mixtures of hydroxyl- and methyl-terminated alkanethiols self-assembled monolayers.

J Biomed Mater Res A 2003 Oct;67(1):158-71

Instituto de Engenharia Biomédica, Laboratório de Biomateriais, and Departmento de Engenharia Metalúrgica e Materias, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1002/jbm.a.10096DOI Listing
October 2003

Adhesion of human leukocytes to biomaterials: an in vitro study using alkanethiolate monolayers with different chemically functionalized surfaces.

J Biomed Mater Res A 2003 Jun;65(4):429-34

INEB-Instituto de Engenharia Biomédica, Laboratório de Biomateriais, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1002/jbm.a.10488DOI Listing
June 2003