Marina Pajic

Marina Pajic

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Marina Pajic

Publications by authors named "Marina Pajic"

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Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy.

Small GTPases 2020 Jan 3;11(1):45-52. Epub 2017 Oct 3.

The Garvan Institute of Medical Research, Sydney, Australia.

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http://dx.doi.org/10.1080/21541248.2017.1345712DOI Listing
January 2020

Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy.

FEBS J 2019 Sep 5;286(18):3510-3539. Epub 2019 Aug 5.

The Kinghorn Cancer Centre, The Garvan Institute of Medical Research, Sydney, Australia.

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http://dx.doi.org/10.1111/febs.15011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771888PMC
September 2019

RET gene rearrangements occur in a subset of pancreatic acinar cell carcinomas.

Mod Pathol 2019 Sep 26. Epub 2019 Sep 26.

Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, NSW, Australia.

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http://dx.doi.org/10.1038/s41379-019-0373-yDOI Listing
September 2019

PAK inhibition by PF-3758309 enhanced the sensitivity of multiple chemotherapeutic reagents in patient-derived pancreatic cancer cell lines.

Am J Transl Res 2019 15;11(6):3353-3364. Epub 2019 Jun 15.

Department of Surgery, University of Melbourne, Austin Health Studley Road, Heidelberg, Victoria 3084, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614655PMC
June 2019

ATRX loss is an independent predictor of poor survival in pancreatic neuroendocrine tumors.

Hum Pathol 2018 12 3;82:249-257. Epub 2018 Aug 3.

Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, NSW 2065, Australia; University of Sydney, Sydney, NSW 2006, Australia; NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2018.07.032DOI Listing
December 2018

The Evolving Understanding of the Molecular and Therapeutic Landscape of Pancreatic Ductal Adenocarcinoma.

Diseases 2018 Nov 13;6(4). Epub 2018 Nov 13.

The Kinghorn Cancer Centre, The Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.3390/diseases6040103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313363PMC
November 2018

Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors.

Pharmacol Res 2018 08 23;134:166-178. Epub 2018 Jun 23.

The University of Sydney, Faculty of Medicine and Health, Charles Perkins Centre, NSW 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2018.06.023DOI Listing
August 2018

BRAF gene rearrangements can be identified by FISH studies in pancreatic acinar cell carcinoma.

Pathology 2018 04 3;50(3):345-348. Epub 2018 Mar 3.

Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, NSW, Australia; University of Sydney, Sydney, NSW, Australia; NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pathol.2017.09.027DOI Listing
April 2018

Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer.

Gastroenterology 2018 03 26;154(4):820-838. Epub 2017 Dec 26.

The Garvan Institute of Medical Research, Sydney, New South Wales, Australia; The Kinghorn Cancer Center, Sydney, New South Wales, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.11.280DOI Listing
March 2018

Selected Alkylating Agents Can Overcome Drug Tolerance of G-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice.

Clin Cancer Res 2017 Nov 18;23(22):7020-7033. Epub 2017 Aug 18.

Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-1279DOI Listing
November 2017

Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours.

Authors:
Aldo Scarpa David K Chang Katia Nones Vincenzo Corbo Ann-Marie Patch Peter Bailey Rita T Lawlor Amber L Johns David K Miller Andrea Mafficini Borislav Rusev Maria Scardoni Davide Antonello Stefano Barbi Katarzyna O Sikora Sara Cingarlini Caterina Vicentini Skye McKay Michael C J Quinn Timothy J C Bruxner Angelika N Christ Ivon Harliwong Senel Idrisoglu Suzanne McLean Craig Nourse Ehsan Nourbakhsh Peter J Wilson Matthew J Anderson J Lynn Fink Felicity Newell Nick Waddell Oliver Holmes Stephen H Kazakoff Conrad Leonard Scott Wood Qinying Xu Shivashankar Hiriyur Nagaraj Eliana Amato Irene Dalai Samantha Bersani Ivana Cataldo Angelo P Dei Tos Paola Capelli Maria Vittoria Davì Luca Landoni Anna Malpaga Marco Miotto Vicki L J Whitehall Barbara A Leggett Janelle L Harris Jonathan Harris Marc D Jones Jeremy Humphris Lorraine A Chantrill Venessa Chin Adnan M Nagrial Marina Pajic Christopher J Scarlett Andreia Pinho Ilse Rooman Christopher Toon Jianmin Wu Mark Pinese Mark Cowley Andrew Barbour Amanda Mawson Emily S Humphrey Emily K Colvin Angela Chou Jessica A Lovell Nigel B Jamieson Fraser Duthie Marie-Claude Gingras William E Fisher Rebecca A Dagg Loretta M S Lau Michael Lee Hilda A Pickett Roger R Reddel Jaswinder S Samra James G Kench Neil D Merrett Krishna Epari Nam Q Nguyen Nikolajs Zeps Massimo Falconi Michele Simbolo Giovanni Butturini George Van Buren Stefano Partelli Matteo Fassan Kum Kum Khanna Anthony J Gill David A Wheeler Richard A Gibbs Elizabeth A Musgrove Claudio Bassi Giampaolo Tortora Paolo Pederzoli John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2017 10 27;550(7677):548. Epub 2017 Sep 27.

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http://dx.doi.org/10.1038/nature24026DOI Listing
October 2017

Transient targeting of the pancreatic cancer stroma as a 'fine-tuned' anti-tumor and anti-metastatic therapy.

Oncotarget 2017 Oct 3;8(49):84635-84636. Epub 2017 Oct 3.

Paul Timpson and Marina Pajic: The Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW & The Kinghorn Cancer Centre, Cancer Division, Australia and St Vincent's Clinical School, Faculty of Medicine, University of NSW, Australia.

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http://dx.doi.org/10.18632/oncotarget.21468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689559PMC
October 2017

Effective modulation of stromal signaling through ROCK inhibition: Is it all in the timing?

Mol Cell Oncol 2017 26;4(5):e1333973. Epub 2017 May 26.

The Kinghorn Cancer Centre, The Garvan Institute of Medical Research, Darlinghurst, Sydney, Australia.

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http://dx.doi.org/10.1080/23723556.2017.1333973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644476PMC
May 2017

Whole-genome landscape of pancreatic neuroendocrine tumours.

Authors:
Aldo Scarpa David K Chang Katia Nones Vincenzo Corbo Ann-Marie Patch Peter Bailey Rita T Lawlor Amber L Johns David K Miller Andrea Mafficini Borislav Rusev Maria Scardoni Davide Antonello Stefano Barbi Katarzyna O Sikora Sara Cingarlini Caterina Vicentini Skye McKay Michael C J Quinn Timothy J C Bruxner Angelika N Christ Ivon Harliwong Senel Idrisoglu Suzanne McLean Craig Nourse Ehsan Nourbakhsh Peter J Wilson Matthew J Anderson J Lynn Fink Felicity Newell Nick Waddell Oliver Holmes Stephen H Kazakoff Conrad Leonard Scott Wood Qinying Xu Shivashankar Hiriyur Nagaraj Eliana Amato Irene Dalai Samantha Bersani Ivana Cataldo Angelo P Dei Tos Paola Capelli Maria Vittoria Davì Luca Landoni Anna Malpaga Marco Miotto Vicki L J Whitehall Barbara A Leggett Janelle L Harris Jonathan Harris Marc D Jones Jeremy Humphris Lorraine A Chantrill Venessa Chin Adnan M Nagrial Marina Pajic Christopher J Scarlett Andreia Pinho Ilse Rooman Christopher Toon Jianmin Wu Mark Pinese Mark Cowley Andrew Barbour Amanda Mawson Emily S Humphrey Emily K Colvin Angela Chou Jessica A Lovell Nigel B Jamieson Fraser Duthie Marie-Claude Gingras William E Fisher Rebecca A Dagg Loretta M S Lau Michael Lee Hilda A Pickett Roger R Reddel Jaswinder S Samra James G Kench Neil D Merrett Krishna Epari Nam Q Nguyen Nikolajs Zeps Massimo Falconi Michele Simbolo Giovanni Butturini George Van Buren Stefano Partelli Matteo Fassan Kum Kum Khanna Anthony J Gill David A Wheeler Richard A Gibbs Elizabeth A Musgrove Claudio Bassi Giampaolo Tortora Paolo Pederzoli John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2017 03 15;543(7643):65-71. Epub 2017 Feb 15.

University of Melbourne Centre for Cancer Research, University of Melbourne, Melbourne, 3010, Victoria, Australia.

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http://dx.doi.org/10.1038/nature21063DOI Listing
March 2017

Hypermutation In Pancreatic Cancer.

Gastroenterology 2017 01 15;152(1):68-74.e2. Epub 2016 Nov 15.

Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales Australia, Liverpool, New South Wales, Australia; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085163518
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http://dx.doi.org/10.1053/j.gastro.2016.09.060DOI Listing
January 2017

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling.

Mol Cell Proteomics 2016 08 3;15(8):2671-85. Epub 2016 Jun 3.

¶Cancer Program, Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Level 1, Building 77, Monash University, VIC 3800, Australia;

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http://dx.doi.org/10.1074/mcp.M116.058313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974343PMC
August 2016

Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis.

Mol Oncol 2016 06 2;10(6):866-78. Epub 2016 Mar 2.

Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Randwick 2031, Australia; Kids Cancer Centre, Sydney Children's Hospital, Randwick 2031, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2016.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423163PMC
June 2016

The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment.

Small GTPases 2015 23;6(2):123-33. Epub 2015 Jun 23.

a The Kinghorn Cancer Center; Cancer Division; Garvan Institute of Medical Research ; Sydney , Australia.

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http://dx.doi.org/10.4161/21541248.2014.973749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601362PMC
April 2016

Genomic analyses identify molecular subtypes of pancreatic cancer.

Authors:
Peter Bailey David K Chang Katia Nones Amber L Johns Ann-Marie Patch Marie-Claude Gingras David K Miller Angelika N Christ Tim J C Bruxner Michael C Quinn Craig Nourse L Charles Murtaugh Ivon Harliwong Senel Idrisoglu Suzanne Manning Ehsan Nourbakhsh Shivangi Wani Lynn Fink Oliver Holmes Venessa Chin Matthew J Anderson Stephen Kazakoff Conrad Leonard Felicity Newell Nick Waddell Scott Wood Qinying Xu Peter J Wilson Nicole Cloonan Karin S Kassahn Darrin Taylor Kelly Quek Alan Robertson Lorena Pantano Laura Mincarelli Luis N Sanchez Lisa Evers Jianmin Wu Mark Pinese Mark J Cowley Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Lorraine A Chantrill Amanda Mawson Jeremy Humphris Angela Chou Marina Pajic Christopher J Scarlett Andreia V Pinho Marc Giry-Laterriere Ilse Rooman Jaswinder S Samra James G Kench Jessica A Lovell Neil D Merrett Christopher W Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Kim Moran-Jones Nigel B Jamieson Janet S Graham Fraser Duthie Karin Oien Jane Hair Robert Grützmann Anirban Maitra Christine A Iacobuzio-Donahue Christopher L Wolfgang Richard A Morgan Rita T Lawlor Vincenzo Corbo Claudio Bassi Borislav Rusev Paola Capelli Roberto Salvia Giampaolo Tortora Debabrata Mukhopadhyay Gloria M Petersen Donna M Munzy William E Fisher Saadia A Karim James R Eshleman Ralph H Hruban Christian Pilarsky Jennifer P Morton Owen J Sansom Aldo Scarpa Elizabeth A Musgrove Ulla-Maja Hagbo Bailey Oliver Hofmann Robert L Sutherland David A Wheeler Anthony J Gill Richard A Gibbs John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2016 Mar 24;531(7592):47-52. Epub 2016 Feb 24.

Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1038/nature16965DOI Listing
March 2016

Imaging fibrosis in pancreatic cancer using second harmonic generation.

Pancreatology 2015 Mar-Apr;15(2):200-1

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http://dx.doi.org/10.1016/j.pan.2015.02.004DOI Listing
December 2015

Second-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials.

Crit Rev Oncol Hematol 2015 Dec 26;96(3):483-97. Epub 2015 Jul 26.

Department of Medical Oncology, The Canberra Hospital, Garran, ACT, Australia; ANU Medical School, Australian National University, Acton, ACT, Australia.

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http://dx.doi.org/10.1016/j.critrevonc.2015.07.007DOI Listing
December 2015

Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities.

Expert Rev Mol Med 2015 Oct 28;17:e17. Epub 2015 Oct 28.

The Kinghorn Cancer Centre,Cancer Division,Garvan Institute of Medical Research,384 Victoria St,Darlinghurst,Sydney,NSW 2010,Australia.

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http://dx.doi.org/10.1017/erm.2015.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836205PMC
October 2015

Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial.

Clin Cancer Res 2015 May;21(9):2029-37

The Kinghorn Cancer Centre, Cancer Division, Garvan Institute of Medical Research, Sydney, New South Wales, Australia. Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland. Department of Surgery, Bankstown Hospital, Sydney, New South Wales, Australia. South Western Sydney Clinical School, Faculty of Medicine, University of NSW, Liverpool, New South Wales, Australia. West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0426DOI Listing
May 2015

Whole genomes redefine the mutational landscape of pancreatic cancer.

Nature 2015 Feb;518(7540):495-501

1] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia [2] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.

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http://dx.doi.org/10.1038/nature14169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523082PMC
February 2015

Clinical and pathologic features of familial pancreatic cancer.

Cancer 2014 Dec 14;120(23):3669-75. Epub 2014 Oct 14.

The Kinghorn Cancer Center, Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1002/cncr.28863DOI Listing
December 2014

Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma.

Clin Cancer Res 2014 Jun 16;20(12):3187-97. Epub 2014 May 16.

Authors' Affiliations: Signal Transduction Laboratory, QIMR Berghofer Medical Research Institute, Herston; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland; The Kinghorn Cancer Centre, Cancer Division, Garvan Institute of Medical Research; St Vincent's Clinical School, Faculty of Medicine, University of NSW; Department of Anatomical Pathology, SYDPATH, St Vincent's Hospital, Darlinghurst, New South Wales; Australian Pancreatic Cancer Genome Initiative, for the full list of contributors see http://www.pancreaticcancer.net.au/apgi/collaborators; Cancer Clinical Trials Unit, Royal Adelaide Hospital Cancer Centre, and Centre for Cancer Biology, SA Pathology; School of Medicine, University of Adelaide, Adelaide, Australia; and Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United KingdomAuthors' Affiliations: Signal Transduction Laboratory, QIMR Berghofer Medical Research Institute, Herston; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland; The Kinghorn Cancer Centre, Cancer Division, Garvan Institute of Medical Research; St Vincent's Clinical School, Faculty of Medicine, University of NSW; Department of Anatomical Pathology, SYDPATH, St Vincent's Hospital, Darlinghurst, New South Wales; Australian Pancreatic Cancer Genome Initiative, for the full list of contributors see http://www.pancreaticcancer.net.au/apgi/collaborators; Cancer Clinical Trials Unit, Royal Adelaide Hospital Cancer Centre, and Centre for Cancer Biology, SA Pathology; School of Medicine, University of Adelaide, Adelaide, Australia; and Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom.

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http://clincancerres.aacrjournals.org/content/early/2014/05/
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http://clincancerres.aacrjournals.org/content/early/2014/05/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-14-0048DOI Listing
June 2014

Clinical and molecular characterization of HER2 amplified-pancreatic cancer.

Genome Med 2013 31;5(8):78. Epub 2013 Aug 31.

Kinghorn Cancer Centre and Garvan Institute of Medical Research, Darlinghurst, Sydney, Australia ; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK ; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, UK.

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http://dx.doi.org/10.1186/gm482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978667PMC
May 2014

An analysis of reported motivational orientation in students undertaking doctoral studies in the biomedical sciences.

BMC Med Educ 2014 Feb 27;14:38. Epub 2014 Feb 27.

School of Women's and Infants' Health, M550, The University of Western Australia, Perth WA6009, Australia.

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http://dx.doi.org/10.1186/1472-6920-14-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974041PMC
February 2014

Understanding pancreatic cancer genomes.

J Hepatobiliary Pancreat Sci 2013 Aug;20(6):549-56

The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, Australia; Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, NSW, 2010, Australia.

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http://dx.doi.org/10.1007/s00534-013-0610-6DOI Listing
August 2013

Signatures of mutational processes in human cancer.

Nature 2013 Aug 14;500(7463):415-21. Epub 2013 Aug 14.

Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature12477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776390PMC
August 2013

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.

Authors:
Andrew V Biankin Nicola Waddell Karin S Kassahn Marie-Claude Gingras Lakshmi B Muthuswamy Amber L Johns David K Miller Peter J Wilson Ann-Marie Patch Jianmin Wu David K Chang Mark J Cowley Brooke B Gardiner Sarah Song Ivon Harliwong Senel Idrisoglu Craig Nourse Ehsan Nourbakhsh Suzanne Manning Shivangi Wani Milena Gongora Marina Pajic Christopher J Scarlett Anthony J Gill Andreia V Pinho Ilse Rooman Matthew Anderson Oliver Holmes Conrad Leonard Darrin Taylor Scott Wood Qinying Xu Katia Nones J Lynn Fink Angelika Christ Tim Bruxner Nicole Cloonan Gabriel Kolle Felicity Newell Mark Pinese R Scott Mead Jeremy L Humphris Warren Kaplan Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Angela Chou Venessa T Chin Lorraine A Chantrill Amanda Mawson Jaswinder S Samra James G Kench Jessica A Lovell Roger J Daly Neil D Merrett Christopher Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Nipun Kakkar Fengmei Zhao Yuan Qing Wu Min Wang Donna M Muzny William E Fisher F Charles Brunicardi Sally E Hodges Jeffrey G Reid Jennifer Drummond Kyle Chang Yi Han Lora R Lewis Huyen Dinh Christian J Buhay Timothy Beck Lee Timms Michelle Sam Kimberly Begley Andrew Brown Deepa Pai Ami Panchal Nicholas Buchner Richard De Borja Robert E Denroche Christina K Yung Stefano Serra Nicole Onetto Debabrata Mukhopadhyay Ming-Sound Tsao Patricia A Shaw Gloria M Petersen Steven Gallinger Ralph H Hruban Anirban Maitra Christine A Iacobuzio-Donahue Richard D Schulick Christopher L Wolfgang Richard A Morgan Rita T Lawlor Paola Capelli Vincenzo Corbo Maria Scardoni Giampaolo Tortora Margaret A Tempero Karen M Mann Nancy A Jenkins Pedro A Perez-Mancera David J Adams David A Largaespada Lodewyk F A Wessels Alistair G Rust Lincoln D Stein David A Tuveson Neal G Copeland Elizabeth A Musgrove Aldo Scarpa James R Eshleman Thomas J Hudson Robert L Sutherland David A Wheeler John V Pearson John D McPherson Richard A Gibbs Sean M Grimmond

Nature 2012 Nov 24;491(7424):399-405. Epub 2012 Oct 24.

The Kinghorn Cancer Centre, 370 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/nature11547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530898PMC
November 2012

Preclinical strategies to define predictive biomarkers for therapeutically relevant cancer subtypes.

Hum Genet 2011 Jul 23;130(1):93-101. Epub 2011 Apr 23.

Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1007/s00439-011-0990-0DOI Listing
July 2011

ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.

Pharmacogenet Genomics 2011 May;21(5):270-9

Children's Cancer Institute Australia for Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1097/FPC.0b013e328343dd5fDOI Listing
May 2011

Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo.

Cell Cycle 2010 Sep 13;9(18):3780-91. Epub 2010 Sep 13.

Division of Molecular Biology of the Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047802PMC
http://dx.doi.org/10.4161/cc.9.18.13002DOI Listing
September 2010

Studying drug resistance using genetically engineered mouse models for breast cancer.

Methods Mol Biol 2010 ;596:33-45

Division of Molecular Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/978-1-60761-416-6_3DOI Listing
January 2010

Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubicin in a mouse model for hereditary breast cancer.

Cancer Res 2009 Aug 4;69(16):6396-404. Epub 2009 Aug 4.

Division of Molecular Biology and Centre for Biomedical Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-09-0041DOI Listing
August 2009

Nucleus pulposus cellular longevity by telomerase gene therapy.

Spine (Phila Pa 1976) 2007 May;32(11):1188-96

Orthopaedic Research Institute, University of New South Wales, St. George Hospital Campus, NSW, Australia.

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http://pdfs.journals.lww.com/spinejournal/2007/05150/Nucleus
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/BRS.0b013e31805471a3DOI Listing
May 2007

The role of the multidrug resistance-associated protein 1 gene in neuroblastoma biology and clinical outcome.

Cancer Lett 2005 Oct;228(1-2):241-6

Children's Cancer Institute Australia for Medical Research, P.O. Box 81 Randwick, Sydney, NSW 2031, Australia.

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http://dx.doi.org/10.1016/j.canlet.2005.01.060DOI Listing
October 2005

Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines.

Oncol Rep 2004 May;11(5):1091-5

Children's Cancer Institute of Australia for Medical Research, Randwick, Sydney, NSW 2031, Australia.

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May 2004