Marilyn Huestis

Marilyn Huestis

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Marilyn Huestis

Publications by authors named "Marilyn Huestis"

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Monitoring Prenatal Exposure to Buprenorphine and Methadone.

Ther Drug Monit 2019 Aug 14. Epub 2019 Aug 14.

Unit of Forensic Toxicology, Department of Anatomical, Histological, Forensic, and Orthopedic Sciences, Università la Sapienza, Viale Regina Elena 366, 00161 Rome, Italy.

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http://dx.doi.org/10.1097/FTD.0000000000000693DOI Listing
August 2019

Oral Fluid Drug Testing: Analytical Approaches, Issues and Interpretation of Results.

J Anal Toxicol 2019 Jul;43(6):415-443

Lambert Center for the Study of Medicinal Cannabis and Hemp, Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/jat/bkz048DOI Listing
July 2019

Monitoring the effects of perinatal cannabis and synthetic cannabinoid exposure.

Ther Drug Monit 2019 Jun 28. Epub 2019 Jun 28.

Section of Legal Medicine, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.1097/FTD.0000000000000667DOI Listing
June 2019

THC and CBD concentrations in blood, oral fluid and urine following a single and repeated administration of "light cannabis".

Clin Chem Lab Med 2019 Apr 8. Epub 2019 Apr 8.

Lambert Center for the Study of Medicinal Cannabis and Hemp, Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1515/cclm-2019-0119DOI Listing
April 2019

Effects of the Psychedelic Amphetamine MDA (3,4-Methylenedioxyamphetamine) in Healthy Volunteers.

J Psychoactive Drugs 2019 Apr-Jun;51(2):108-117. Epub 2019 Apr 9.

a Addiction and Pharmacology Research Laboratory , Friends Research Institute , San Francisco , CA , USA.

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http://dx.doi.org/10.1080/02791072.2019.1593560DOI Listing
April 2019

Prenatal exposure to tobacco and marijuana and child autonomic regulation and reactivity: An analysis of indirect pathways via maternal psychopathology and parenting.

Dev Psychobiol 2019 Mar 13. Epub 2019 Mar 13.

The Lambert Center for the Study of Medicinal Cannabis and Hemp, Thomas Jefferson, Philadelphia, PA.

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http://dx.doi.org/10.1002/dev.21844DOI Listing
March 2019

New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites.

Front Chem 2019 4;7:109. Epub 2019 Mar 4.

The Lambert Center for the Study of Medicinal Cannabis and Hemp, Institute for Emerging Health Professions, Thomas Jefferson University, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fchem.2019.00109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409358PMC
March 2019

Cannabidiol Adverse Effects and Toxicity.

Curr Neuropharmacol 2019 ;17(10):974-989

Section of Legal Medicine, Universita Politecnica delle Marche, Ancona, Italy.

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http://www.eurekaselect.com/172430/article
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http://dx.doi.org/10.2174/1570159X17666190603171901DOI Listing
January 2019

Pharmacodynamic Effects, Pharmacokinetics, and Metabolism of the Synthetic Cannabinoid AM-2201 in Male Rats.

J Pharmacol Exp Ther 2018 12 28;367(3):543-550. Epub 2018 Sep 28.

Chemistry and Drug Metabolism (J.C., A.W., K.B.S., M.A.H.) and Designer Drug Research Unit (B.D.S., M.H.B.), Intramural Research Program, National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Baltimore, Maryland

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http://dx.doi.org/10.1124/jpet.118.250530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246978PMC
December 2018

Prenatal tobacco and marijuana co-use: Impact on newborn neurobehavior.

Neurotoxicol Teratol 2018 Nov - Dec;70:28-39. Epub 2018 Sep 26.

Institute for Emerging Health Professions, Thomas Jefferson University, 1020 Walnut Street, Philadelphia, PA 19107, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08920362183002
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http://dx.doi.org/10.1016/j.ntt.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239899PMC
September 2018

Synthetic cannabinoid BB-22 (QUCHIC): Human hepatocytes metabolism with liquid chromatography-high resolution mass spectrometry detection.

J Pharm Biomed Anal 2018 Aug 7;157:27-35. Epub 2018 May 7.

Chemistry & Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD, 21224, USA; Institute of Emerging Health Professions, Thomas Jefferson University, 1020 Walnut Street, Philadelphia, PA, 19107, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2018.05.007DOI Listing
August 2018

Co-use of tobacco and marijuana during pregnancy: Pathways to externalizing behavior problems in early childhood.

Neurotoxicol Teratol 2018 Sep - Oct;69:39-48. Epub 2018 Aug 4.

Institute of Emerging Health Professions, Thomas Jefferson University, 1020 Walnut Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.ntt.2018.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396313PMC
August 2018

Prenatal exposure to tobacco and cannabis: Effects on autonomic and emotion regulation.

Neurotoxicol Teratol 2018 Jul - Aug;68:47-56. Epub 2018 May 1.

Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.ntt.2018.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161361PMC
May 2018

Recent Self-Reported Cannabis Use Is Associated With the Biometrics of Delta-9-Tetrahydrocannabinol.

J Stud Alcohol Drugs 2018 05;79(3):441-446

Warren Wright Adolescent Center, Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005260PMC
http://dx.doi.org/10.15288/jsad.2018.79.441DOI Listing
May 2018

Drug exposure during pregnancy: analytical methods and toxicological findings.

Bioanalysis 2018 Apr 21;10(8):587-606. Epub 2018 Mar 21.

Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.4155/bio-2017-0260DOI Listing
April 2018

Optimization of recombinant β-glucuronidase hydrolysis and quantification of eight urinary cannabinoids and metabolites by liquid chromatography tandem mass spectrometry.

Drug Test Anal 2018 Mar 16;10(3):518-529. Epub 2017 Aug 16.

Chemistry and Drug Metabolism Section, IRP, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1002/dta.2230DOI Listing
March 2018

Cannabinoid Markers in Biological Fluids and Tissues: Revealing Intake.

Trends Mol Med 2018 02;24(2):156-172

Huestis & Smith Toxicology LLC, Severna Park, MD, USA.

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http://dx.doi.org/10.1016/j.molmed.2017.12.006DOI Listing
February 2018

Tobacco exposure and maternal psychopathology: Impact on toddler problem behavior.

Neurotoxicol Teratol 2016 Sep - Oct;57:87-94. Epub 2016 Aug 3.

University of Maryland School of Medicine, United States.

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http://dx.doi.org/10.1016/j.ntt.2016.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059373PMC
December 2017

Adolescent cortical thickness pre- and post marijuana and alcohol initiation.

Neurotoxicol Teratol 2016 Sep - Oct;57:20-29. Epub 2016 Sep 26.

University of California San Diego, Department of Psychiatry, La Jolla, CA, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072451PMC
http://dx.doi.org/10.1016/j.ntt.2016.09.005DOI Listing
December 2017

Reprint of "Adolescent cortical thickness pre- and post marijuana and alcohol initiation".

Neurotoxicol Teratol 2016 Nov - Dec;58:78-87. Epub 2016 Nov 15.

University of California San Diego, Department of Psychiatry, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ntt.2016.11.003DOI Listing
December 2017

Modelling foetal exposure to maternal smoking using hepatoblasts from pluripotent stem cells.

Arch Toxicol 2017 Nov 16;91(11):3633-3643. Epub 2017 May 16.

Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, Scotland, UK.

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http://dx.doi.org/10.1007/s00204-017-1983-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696490PMC
November 2017

Human Hepatocyte Metabolism of Novel Synthetic Cannabinoids MN-18 and Its 5-Fluoro Analog 5F-MN-18.

Clin Chem 2017 Nov 18;63(11):1753-1763. Epub 2017 Aug 18.

Chemistry and Drug Metabolism, IRP, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD;

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http://dx.doi.org/10.1373/clinchem.2017.277152DOI Listing
November 2017

Acute effects of intravenous cocaine administration on serum concentrations of ghrelin, amylin, glucagon-like peptide-1, insulin, leptin and peptide YY and relationships with cardiorespiratory and subjective responses.

Drug Alcohol Depend 2017 11 31;180:68-75. Epub 2017 Aug 31.

Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, 10 Center Drive (10CRC/15330), Bethesda, MD 20892, United States; Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, Brown University, Providence, RI 02906, United States. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2017.07.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654385PMC
November 2017

Erratum to: Modelling foetal exposure to maternal smoking using hepatoblasts from pluripotent stem cells.

Arch Toxicol 2017 11;91(11):3645

Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, Scotland, UK.

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http://dx.doi.org/10.1007/s00204-017-2075-xDOI Listing
November 2017

Impact of Novel Psychoactive Substances on Clinical and Forensic Toxicology and Global Public Health.

Clin Chem 2017 10 30;63(10):1564-1569. Epub 2017 Jun 30.

Staff Scientist and Facility Head, Designer Drug Research Unit, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD.

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http://dx.doi.org/10.1373/clinchem.2017.274662DOI Listing
October 2017

Reports of Adverse Events Associated with Use of Novel Psychoactive Substances, 2013-2016: A Review.

J Anal Toxicol 2017 Sep;41(7):573-610

Center for Forensic Science Research and Education at the Fredric Rieders Family Foundation, 2300 Stratford Ave, Willow Grove, PA 19090, USA.

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http://dx.doi.org/10.1093/jat/bkx031DOI Listing
September 2017

Evaluation of divided attention psychophysical task performance and effects on pupil sizes following smoked, vaporized and oral cannabis administration.

J Appl Toxicol 2017 08 31;37(8):922-932. Epub 2017 Jan 31.

Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/jat.3440DOI Listing
August 2017

Neuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related Analogs.

Curr Top Behav Neurosci 2017 ;32:93-117

Chemistry and Drug Metabolism Section of the Intramural Research Program, National Institute on Drug Abuse (NIDA), National Institutes of Health, Baltimore, MD, USA.

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http://link.springer.com/10.1007/7854_2016_53
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http://dx.doi.org/10.1007/7854_2016_53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392131PMC
July 2017

Tobacco Exposure and Conditional Weight-for-Length Gain by 2 Years of Age.

J Pediatr Psychol 2017 07;42(6):679-688

Research Institute on Addictions, State University of New York at Buffalo.

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http://dx.doi.org/10.1093/jpepsy/jsw095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896634PMC
July 2017

The acute effect of cannabis on plasma, liver and brain ammonia dynamics, a translational study.

Eur Neuropsychopharmacol 2017 07 26;27(7):679-690. Epub 2017 Apr 26.

Neural Engineering Unit, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2017.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091863PMC
July 2017

Erratum to: Modelling foetal exposure to maternal smoking using hepatoblasts from pluripotent stem cells.

Arch Toxicol 2017 Jul 21. Epub 2017 Jul 21.

Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, Scotland, UK.

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http://dx.doi.org/10.1007/s00204-017-2030-xDOI Listing
July 2017

Metabolite Profiling of ADB-FUBINACA, A New Synthetic Cannabinoid.

Curr Neuropharmacol 2017 Jul;15(5):682-691

Chemistry and Drug Metabolism Section, Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd, Suite 200 Room 05A727, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.2174/1570159X15666161108123419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771045PMC
July 2017

Cannabinoid disposition in oral fluid after controlled smoked, vaporized, and oral cannabis administration.

Drug Test Anal 2017 Jun 13;9(6):905-915. Epub 2016 Oct 13.

Chemistry and Drug Metabolism Section, Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/dta.2092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357602PMC
June 2017

Subjective and physiological effects, and expired carbon monoxide concentrations in frequent and occasional cannabis smokers following smoked, vaporized, and oral cannabis administration.

Drug Alcohol Depend 2017 06 29;175:67-76. Epub 2017 Mar 29.

Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse National Institutes of Health, Baltimore, MD, United States; University of Maryland School of Medicine, Baltimore, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2017.02.003DOI Listing
June 2017

25C-NBOMe and 25I-NBOMe metabolite studies in human hepatocytes, in vivo mouse and human urine with high-resolution mass spectrometry.

Drug Test Anal 2017 May 12;9(5):680-698. Epub 2016 Aug 12.

Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, 58758, Linköping, Sweden.

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http://dx.doi.org/10.1002/dta.2044DOI Listing
May 2017

Distinguishing Intake of New Synthetic Cannabinoids ADB-PINACA and 5F-ADB-PINACA with Human Hepatocyte Metabolites and High-Resolution Mass Spectrometry.

Clin Chem 2017 05 16;63(5):1008-1021. Epub 2017 Mar 16.

Chemistry & Drug Metabolism Section, Clinical Pharmacology & Therapeutics Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD;

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http://dx.doi.org/10.1373/clinchem.2016.267575DOI Listing
May 2017

Smoking in Pregnancy and Fetal Growth: The Case for More Intensive Assessment.

Nicotine Tob Res 2017 May;19(5):525-531

Department of Community Health and Health Behavior, State University of New York at Buffalo, Buffalo, NY.

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http://dx.doi.org/10.1093/ntr/ntx018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868096PMC
May 2017

Sativex Associated With Behavioral-Relapse Prevention Strategy as Treatment for Cannabis Dependence: A Case Series.

J Addict Med 2016 Jul-Aug;10(4):274-9

Translational Addiction Research Laboratory, Campbell Family Mental Health, Research Institute (JMT, AS, GS, BLF); Clinical Research (LQ); Social and Epidemiological Research Department (BF, JR); Schizophrenia Division and Complex Mental Illness Program, Centre for Addiction and Mental Health (CAMH), Toronto, Canada (TPG); Addiction Policy, Dalla Lana School of Public Health (JR); Institute of Medical Science, University of Toronto, Faculty of Medicine (BF, JR); Department of Psychiatry, University of Toronto, Toronto, Canada (BF, TPG, JR, PS); Institute of Clinical Psychology and Psychotherapy & Center of Clinical Epidemiology and Longitudinal Studies (CELOS), Technische Universität Dresden, Dresden, Germany (JR); Addictions Division, CAMH (PS, BLF); Department of Family and Community Medicine, University of Toronto, Toronto (PS); Centre for Applied Research in Mental Health & Addiction, Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada (BF); and Chemistry and Drug Metabolism, National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Baltimore, MD (AJB, MAH).

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http://dx.doi.org/10.1097/ADM.0000000000000229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586546PMC
April 2017

Identification of New Synthetic Cannabinoid ADB-CHMINACA (MAB-CHMINACA) Metabolites in Human Hepatocytes.

AAPS J 2017 03 9;19(2):568-577. Epub 2017 Jan 9.

Chemistry & Drug Metabolism Section, Clinical Pharmacology & Therapeutics Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, 21224, USA.

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http://dx.doi.org/10.1208/s12248-016-0037-5DOI Listing
March 2017

Pharmacokinetic Profiles and Pharmacodynamic Effects for Methylone and Its Metabolites in Rats.

Neuropsychopharmacology 2017 02 23;42(3):649-660. Epub 2016 Sep 23.

Designer Drug Research Unit, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/npp.2016.213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240186PMC
February 2017

Cocaine and benzoylecgonine oral fluid on-site screening and confirmation.

Drug Test Anal 2016 Mar-Apr;8(3-4):296-303. Epub 2016 Mar 9.

Chemistry and Drug Metabolism Section, IRP, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/dta.1966DOI Listing
January 2017

Long-term stability of cannabinoids in oral fluid after controlled cannabis administration.

Drug Test Anal 2017 Jan 13;9(1):143-147. Epub 2016 Sep 13.

Chemistry and Drug Metabolism Section, Clinical Pharmacology and Therapeutics Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1002/dta.2056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233598PMC
January 2017

In vitro and in vivo human metabolism of a new synthetic cannabinoid NM-2201 (CBL-2201).

Forensic Toxicol 2017 Jan 6;35(1):20-32. Epub 2016 Jul 6.

Chemistry and Drug Metabolism Section, Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd, Suite 200 Room 05A727, Baltimore, MD 21224, USA ; University of Maryland School of Medicine, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1007/s11419-016-0326-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342258PMC
January 2017

Free and Glucuronide Whole Blood Cannabinoids' Pharmacokinetics after Controlled Smoked, Vaporized, and Oral Cannabis Administration in Frequent and Occasional Cannabis Users: Identification of Recent Cannabis Intake.

Clin Chem 2016 Dec 10;62(12):1579-1592. Epub 2016 Oct 10.

Chemistry and Drug Metabolism Section, IRP, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD.

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http://dx.doi.org/10.1373/clinchem.2016.263475DOI Listing
December 2016

Cannabis effects on driving longitudinal control with and without alcohol.

J Appl Toxicol 2016 11 18;36(11):1418-29. Epub 2016 Feb 18.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, 251 Bayview Boulevard Street, 200 Rm 05A721, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/jat.3295DOI Listing
November 2016

Fatty Acid Amide Hydrolase Binding in Brain of Cannabis Users: Imaging With the Novel Radiotracer [C]CURB.

Biol Psychiatry 2016 11 25;80(9):691-701. Epub 2016 Apr 25.

Human Brain Lab, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050070PMC
http://dx.doi.org/10.1016/j.biopsych.2016.04.012DOI Listing
November 2016

Effects of fetal tobacco exposure on focused attention in infancy.

Infant Behav Dev 2016 Nov 18;45(Pt A):1-10. Epub 2016 Aug 18.

Department of Psychology, State University of New York at Buffalo, 227 Park Hall, Buffalo, NY 14260, United States. Electronic address:

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http://dx.doi.org/10.1016/j.infbeh.2016.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191843PMC
November 2016

Maternal Buprenorphine Maintenance and Lactation.

J Hum Lact 2016 Nov 26;32(4):675-681. Epub 2016 Sep 26.

6 University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/0890334416663198DOI Listing
November 2016

Metabolism of Carfentanil, an Ultra-Potent Opioid, in Human Liver Microsomes and Human Hepatocytes by High-Resolution Mass Spectrometry.

AAPS J 2016 11 5;18(6):1489-1499. Epub 2016 Aug 5.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, 21224, USA.

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http://dx.doi.org/10.1208/s12248-016-9963-5DOI Listing
November 2016

In Vitro Metabolite Profiling of ADB-FUBINACA, A New Synthetic Cannabinoid.

Curr Neuropharmacol 2016 Nov 8. Epub 2016 Nov 8.

Clinical Pharmacology and Therapeutics Branch, Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, Biomedical Research Center, 251 Bayview Boulevard, Suite 200 Room 05A-729, Baltimore, MD 21224, USA.

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November 2016

Naloxone and Metabolites Quantification in Cord Blood of Prenatally Exposed Newborns and Correlations with Maternal Concentrations.

AJP Rep 2016 Oct;6(4):e385-e390

Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1055/s-0036-1593993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120978PMC
October 2016

Simultaneous quantification of 11 cannabinoids and metabolites in human urine by liquid chromatography tandem mass spectrometry using WAX-S tips.

Anal Bioanal Chem 2016 Sep 15;408(23):6461-71. Epub 2016 Jul 15.

Chemistry and Drug Metabolism Section, Clinical Pharmacology and Therapeutics Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1007/s00216-016-9765-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010516PMC
September 2016

A preliminary evaluation of the relationship of cannabinoid blood concentrations with the analgesic response to vaporized cannabis.

J Pain Res 2016 31;9:587-98. Epub 2016 Aug 31.

VA Northern California Health Care System, Mather, CA; Department of Physical Medicine and Rehabilitation, University of California, Sacramento, CA.

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http://dx.doi.org/10.2147/JPR.S113138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012851PMC
September 2016

One Hundred False-Positive Amphetamine Specimens Characterized by Liquid Chromatography Time-of-Flight Mass Spectrometry.

J Anal Toxicol 2016 Jan-Feb;40(1):37-42. Epub 2015 Sep 4.

ARUP Laboratories, Inc., 500 Chipeta Way, Salt Lake City, UT 84108-1221, USA Department of Pathology, University of Utah Health Science Center, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1093/jat/bkv101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731401PMC
August 2016

Comparison of (+)- and (-)-Naloxone on the Acute Psychomotor-Stimulating Effects of Heroin, 6-Acetylmorphine, and Morphine in Mice.

J Pharmacol Exp Ther 2016 08 8;358(2):209-15. Epub 2016 Jun 8.

Department of Drug Abuse Research, Division for Forensic Sciences, Norwegian Institute of Public Health, Oslo, Norway (G.S.E., J.M.A., F.B., M.S.-S.B., V.V., J.M.); Institute of Clinical Medicine, University of Oslo, Oslo, Norway (V.V., J.M.); University of Maryland School of Medicine, Baltimore, Maryland (M.A.H.); and Section on Drug Design and Synthesis, National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland (K.C.R).

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http://dx.doi.org/10.1124/jpet.116.233544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959094PMC
August 2016

Extended plasma cannabinoid excretion in chronic frequent cannabis smokers during sustained abstinence and correlation with psychomotor performance.

Drug Test Anal 2016 Jul 11;8(7):682-9. Epub 2015 Jun 11.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd. Suite 05A721, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1002/dta.1825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676741PMC
July 2016

Controlled vaporized cannabis, with and without alcohol: subjective effects and oral fluid-blood cannabinoid relationships.

Drug Test Anal 2016 Jul 10;8(7):690-701. Epub 2015 Aug 10.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/dta.1839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749481PMC
July 2016

Drug Recognition Expert (DRE) examination characteristics of cannabis impairment.

Accid Anal Prev 2016 Jul 22;92:219-29. Epub 2016 Apr 22.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Boulevard Ste 200 Rm 05A721, Baltimore, MD, 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.aap.2016.04.012DOI Listing
July 2016

First metabolic profile of PV8, a novel synthetic cathinone, in human hepatocytes and urine by high-resolution mass spectrometry.

Anal Bioanal Chem 2016 Jul 16;408(18):4845-56. Epub 2016 May 16.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd. Suite 05A721, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1007/s00216-016-9599-4DOI Listing
July 2016

Quantification of cannabinoids and their free and glucuronide metabolites in whole blood by disposable pipette extraction and liquid chromatography-tandem mass spectrometry.

J Chromatogr A 2016 Jul 7;1453:34-42. Epub 2016 May 7.

Chemistry and Drug Metabolism Section, IRP, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.chroma.2016.05.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955402PMC
July 2016

MDMA Impairs Response to Water Intake in Healthy Volunteers.

Adv Pharmacol Sci 2016 14;2016:2175896. Epub 2016 Jun 14.

Addiction and Pharmacology Research Laboratory, Friends Research Institute, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1155/2016/2175896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923534PMC
July 2016

Cocaine and metabolite concentrations in DBS and venous blood after controlled intravenous cocaine administration.

Bioanalysis 2015 ;7(16):2041-56

Chemistry & Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.4155/bio.15.127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644129PMC
June 2016

Pharmacodynamic effects and relationships to plasma and oral fluid pharmacokinetics after intravenous cocaine administration.

Drug Alcohol Depend 2016 Jun 13;163:116-25. Epub 2016 Apr 13.

Chemistry and Drug Metabolism Section, IRP, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2016.04.004DOI Listing
June 2016

Quantification of [1-(5-fluoropentyl)-1H-indol-3-yl](naphthalene-1-yl)methanone (AM-2201) and 13 metabolites in human and rat plasma by liquid chromatography-tandem mass spectrometry.

J Chromatogr A 2016 Jun 6;1451:97-106. Epub 2016 May 6.

Clinical Pharmacology & Therapeutics Research Branch, Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), 251 Bayview Boulevard Suite 200, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.chroma.2016.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886661PMC
June 2016

Simultaneous quantification of buprenorphine, naloxone and phase I and II metabolites in plasma and breastmilk by liquid chromatography-tandem mass spectrometry.

J Chromatogr A 2016 May 31;1446:70-7. Epub 2016 Mar 31.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2016.03.076DOI Listing
May 2016

Synthetic cathinone pharmacokinetics, analytical methods, and toxicological findings from human performance and postmortem cases.

Drug Metab Rev 2016 05 1;48(2):237-65. Epub 2016 Jun 1.

a Chemistry and Drug Metabolism, IRP , National Institute on Drug Abuse, National Institutes of Health , Baltimore , MD , USA ;

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http://dx.doi.org/10.1080/03602532.2016.1188937DOI Listing
May 2016

Effects of fixed or self-titrated dosages of Sativex on cannabis withdrawal and cravings.

Drug Alcohol Depend 2016 Apr 23;161:298-306. Epub 2016 Feb 23.

Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada; Addictions Division, CAMH, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2016.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878903PMC
April 2016

Metabolic profiling of new synthetic cannabinoids AMB and 5F-AMB by human hepatocyte and liver microsome incubations and high-resolution mass spectrometry.

Rapid Commun Mass Spectrom 2016 Apr;30(8):1067-78

Chemistry and Drug Metabolism, IRP, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, 21224, USA.

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https://www.researchgate.net/profile/Xingxing_Diao/publicati
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http://doi.wiley.com/10.1002/rcm.7538
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http://dx.doi.org/10.1002/rcm.7538DOI Listing
April 2016

School-Aged Outcomes following Prenatal Methamphetamine Exposure: 7.5-Year Follow-Up from the Infant Development, Environment, and Lifestyle Study.

J Pediatr 2016 Mar 11;170:34-8.e1. Epub 2016 Jan 11.

Pediatrics Division, Brown Center for the Study of Children at Risk, Warren Alpert Medical School of Brown University, Women and Infants Hospital, Providence, RI.

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http://dx.doi.org/10.1016/j.jpeds.2015.11.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769906PMC
March 2016

In Vitro and In Vivo Human Metabolism of Synthetic Cannabinoids FDU-PB-22 and FUB-PB-22.

AAPS J 2016 Mar 25;18(2):455-64. Epub 2016 Jan 25.

Chemistry and Drug Metabolism, IRP, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd, Suite 200 Room 05A721, Baltimore, Maryland, 21224, USA.

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http://link.springer.com/content/pdf/10.1208%2Fs12248-016-98
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http://link.springer.com/10.1208/s12248-016-9867-4
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http://dx.doi.org/10.1208/s12248-016-9867-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779098PMC
March 2016

Oral fluid cocaine and benzoylecgonine concentrations following controlled intravenous cocaine administration.

Forensic Sci Int 2016 Mar 22;260:95-101. Epub 2016 Jan 22.

Chemistry and Drug Metabolism Section, IRP, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD. Electronic address:

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http://dx.doi.org/10.1016/j.forsciint.2016.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761476PMC
March 2016

Strategies to distinguish new synthetic cannabinoid FUBIMINA (BIM-2201) intake from its isomer THJ-2201: metabolism of FUBIMINA in human hepatocytes.

Forensic Toxicol 2016;34:256-267. Epub 2016 Mar 28.

Chemistry and Drug Metabolism, IRP, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Blvd, Suite 200 Room 05A721, Baltimore, MD 21224 USA.

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http://dx.doi.org/10.1007/s11419-016-0312-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971051PMC
March 2016

Extended Detection of Amphetamine and Methamphetamine in Oral Fluid.

Ther Drug Monit 2016 Feb;38(1):114-9

*Division of Forensic Sciences, Norwegian Institute of Public Health; †Trasoppklinikken, Oslo, Norway; ‡Chemistry and Drug Metabolism Section, IRP, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland; and §Department of Pharmaceutical Chemistry, School of Pharmacy, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1097/FTD.0000000000000248DOI Listing
February 2016

Effect of Blood Collection Time on Measured Δ9-Tetrahydrocannabinol Concentrations: Implications for Driving Interpretation and Drug Policy.

Clin Chem 2016 Feb;62(2):367-77

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, MD;

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http://dx.doi.org/10.1373/clinchem.2015.248492DOI Listing
February 2016

High-Resolution Mass Spectrometry for Characterizing the Metabolism of Synthetic Cannabinoid THJ-018 and Its 5-Fluoro Analog THJ-2201 after Incubation in Human Hepatocytes.

Clin Chem 2016 Jan 1;62(1):157-69. Epub 2015 Oct 1.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, MD;

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http://dx.doi.org/10.1373/clinchem.2015.243535DOI Listing
January 2016

Urine Mescaline Screening With a Biochip Array Immunoassay and Quantification by Gas Chromatography-Mass Spectrometry.

Ther Drug Monit 2015 Dec;37(6):805-11

*Department of Toxicology, Faculty of Pharmacy, Mersin University, Turkey; †Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland; and ‡Drug Testing and Program Policy, Office of the Secretary of Defense, Operational Readiness and Safety, Washington, District of Columbia.

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http://dx.doi.org/10.1097/FTD.0000000000000220DOI Listing
December 2015

Deterring driving under the influence of cannabis.

Addiction 2015 Nov 12;110(11):1697-8. Epub 2015 Aug 12.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1111/add.13041DOI Listing
November 2015

Cannabis-impaired driving: a public health and safety concern.

Clin Chem 2015 Oct 17;61(10):1223-5. Epub 2015 Aug 17.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, MD.

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http://dx.doi.org/10.1373/clinchem.2015.245001DOI Listing
October 2015

Plasma Cannabinoid Pharmacokinetics After Controlled Smoking and Ad libitum Cannabis Smoking in Chronic Frequent Users.

J Anal Toxicol 2015 Oct;39(8):580-7

Chemistry and Drug Metabolism, IRP, National Institute on Drug Abuse, NIH, Biomedical Research Center, 251 Bayview Blvd. Room 05A721, Baltimore, MD 21224, USA

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http://dx.doi.org/10.1093/jat/bkv082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570940PMC
October 2015

Cannabis effects on driving lateral control with and without alcohol.

Drug Alcohol Depend 2015 Sep 23;154:25-37. Epub 2015 Jun 23.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, 251 Bayview Boulevard Ste 200 Rm 05A721, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2015.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536116PMC
September 2015

Antiretroviral Drugs in Meconium: Detection for Different Gestational Periods of Exposure.

J Pediatr 2015 Aug 19;167(2):305-11.e3. Epub 2015 May 19.

Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2015.04.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516688PMC
August 2015

Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation.

Cancer Epidemiol Biomarkers Prev 2015 Aug 26;24(8):1239-46. Epub 2015 May 26.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada. Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-1381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526326PMC
August 2015

4-Methoxy-α-PVP: in silico prediction, metabolic stability, and metabolite identification by human hepatocyte incubation and high-resolution mass spectrometry.

Forensic Toxicol 2016;34:61-75. Epub 2015 Aug 5.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 251 Bayview Boulevard, Suite 200 Room 05A-721, Baltimore, MD 21224 USA.

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http://dx.doi.org/10.1007/s11419-015-0287-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705136PMC
August 2015

Meconium Atazanavir Concentrations and Early Language Outcomes in HIV-Exposed Uninfected Infants With Prenatal Atazanavir Exposure.

J Acquir Immune Defic Syndr 2015 Jun;69(2):178-86

*Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD; †Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA; ‡Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD; §Speech, Language, Hearing Department, University of Kansas, Lawrence, KS; ‖Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA; and ¶Department of Research Pediatrics, Maternal, Child, and Adolescent Program for Infectious Diseases and Virology, Keck School of Medicine of USC, Los Angeles, CA.

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http://dx.doi.org/10.1097/QAI.0000000000000558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887272PMC
June 2015

Controlled Cannabis Vaporizer Administration: Blood and Plasma Cannabinoids with and without Alcohol.

Clin Chem 2015 Jun 27;61(6):850-69. Epub 2015 May 27.

Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, MD;

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http://dx.doi.org/10.1373/clinchem.2015.238287DOI Listing
June 2015