Marily Theodoropoulou

Marily Theodoropoulou

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Marily Theodoropoulou

Marily Theodoropoulou

Publications by authors named "Marily Theodoropoulou"

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Geoffrey Harris Award 2019: Translational research in pituitary tumors.

Eur J Endocrinol 2019 Nov 1. Epub 2019 Nov 1.

U Renner, Neuroendocrinology, Max-Planck-Institute for Psychiatry, Munich, Germany.

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http://dx.doi.org/10.1530/EJE-19-0677DOI Listing
November 2019

Therapeutic options after surgical failure in Cushing's disease: A critical review.

Best Pract Res Clin Endocrinol Metab 2019 04 16;33(2):101270. Epub 2019 Apr 16.

Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.beem.2019.04.004DOI Listing
April 2019

Tumor-Directed Therapeutic Targets in Cushing Disease.

J Clin Endocrinol Metab 2019 03;104(3):925-933

Medizinische Klinik und Poliklinik IV, Ludwig Maximilian University Munich, Munich, Germany.

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http://dx.doi.org/10.1210/jc.2018-02080DOI Listing
March 2019

Genetics of Cushing's disease.

Clin Endocrinol (Oxf) 2018 Jan 22;88(1):3-12. Epub 2017 Sep 22.

Medizinische Klinik und Poliklinik IV, Klinikum der Universität, Ludwig-Maximilians-Universität München, Munich, Germany.

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http://dx.doi.org/10.1111/cen.13457DOI Listing
January 2018

Expression and mutational status of in tumors causing ectopic ACTH secretion syndrome.

Endocr Relat Cancer 2017 09 14;24(9):L73-L77. Epub 2017 Jul 14.

Medizinische Klinik und Poliklinik IVLudwig-Maximilians-Universität München, Munich, Germany

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http://dx.doi.org/10.1530/ERC-17-0054DOI Listing
September 2017

A rare case of an ACTH/CRH co-secreting midgut neuroendocrine tumor mimicking Cushing's disease.

Endocrinol Diabetes Metab Case Rep 2017 16;2017. Epub 2017 Jun 16.

Division of Endocrinology and Diabetes, Department of Internal Medicine.

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http://dx.doi.org/10.1530/EDM-17-0058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488327PMC
June 2017

In vitro impact of pegvisomant on growth hormone-secreting pituitary adenoma cells.

Endocr Relat Cancer 2016 07 7;23(7):509-19. Epub 2016 Jun 7.

Aix-Marseille UniversityCNRS, CRN2M UMR7286, Marseille, France APHMConception, Laboratory of Molecular Biology, Marseille, France

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http://dx.doi.org/10.1530/ERC-16-0140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064756PMC
July 2016

Differential Effects of PI3K and Dual PI3K/mTOR Inhibition in Rat Prolactin-Secreting Pituitary Tumors.

Mol Cancer Ther 2016 06 16;15(6):1261-70. Epub 2016 Mar 16.

INSERM U1052, CNRS UMR5286, Cancer Research Center of Lyon, Lyon, France. Université Lyon 1, Lyon, France. Fédération d'Endocrinologie, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0891DOI Listing
June 2016

Octreotide-Mediated Tumor-Targeted Drug Delivery via a Cleavable Doxorubicin-Peptide Conjugate.

Mol Pharm 2015 Dec 17;12(12):4290-300. Epub 2015 Nov 17.

Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany.

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http://dx.doi.org/10.1021/acs.molpharmaceut.5b00487DOI Listing
December 2015

Decoding the genetic basis of Cushing's disease: USP8 in the spotlight.

Eur J Endocrinol 2015 Oct 26;173(4):M73-83. Epub 2015 May 26.

Department of EndocrinologyMax Planck Institute of Psychiatry, Kraepelinstrasse 10, Munich 80804, GermanyMedizinische Klinik und Poliklinik IVLudwig-Maximilians-Universität München, Munich, GermanyEndocrine and Diabetes UnitDepartment of Medicine I, University Hospital, University of Würzburg, Würzburg, GermanyDepartment of Biological SciencesTokyo Institute of Technology, 4259-B16 Nagatsuta, Midori, Yokohama 226-8501, Japan

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http://dx.doi.org/10.1530/EJE-15-0320DOI Listing
October 2015

Coexisting Prolactinoma and Primary Aldosteronism: Is There a Pathophysiological Link?

J Clin Endocrinol Metab 2015 Sep 15;100(9):E1262-9. Epub 2015 Jul 15.

Medizinische Klinik und Poliklinik IV (T.A.W., A.S.D., A.R., E.F., M.B., J.S., F.B., M.R.) and Klinische Radiologie (M.Tr., L.G.), Klinikum der Ludwig-Maximilians-Universität München, 80336 Munich, Germany; Division of Internal Medicine and Hypertension (T.A.W., J.B., F.V., P.M.), Department of Medical Sciences, University of Turin, 10126 Turin, Italy; and Department of Endocrinology (M.Th.), Max Planck Institute of Psychiatry, 80804 Munich, Germany.

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http://dx.doi.org/10.1210/JC.2015-2422DOI Listing
September 2015

The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease.

J Clin Endocrinol Metab 2015 Jul 5;100(7):E997-1004. Epub 2015 May 5.

Medizinische Klinik und Poliklinik IV (L.G.P.-R., C.N., C.M.B., F.B., M.R.), Ludwig-Maximilians-Universität München, 80336 Munich, Germany; Department of Endocrinology (M.The., C.D., G.S.), Max Planck Institute of Psychiatry, 80804 Munich, Germany; Centre for Endocrinology (F.F., M.Kor.), William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, EC1M 6BQ London, United Kingdom; Department of Biological Sciences (K.K., A.I.A., M.Kom.), Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Midori 226-8501 Yokohama, Japan; Section on Endocrinology and Genetics (C.A.S., F.R.F.), Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-2425; Division of Endocrinology (L.E.W., M.R.G.), Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, 21941-913 Rio de Janeiro, Brazil; Inserm Unité 1016 (G.A., J.B.), Centre National de la Recherche Scientifique Unité Mixte de Recherche, Institut Cochin, Université Paris Descartes, 75014 Paris, France; Department of Neuropathology (R.B.), Institute of Pathology and Neuropathology, Eberhard Karls University Tübingen, 72076 Tübingen, Germany; Neurochirurgische Klinik (M.B.), Klinikum der Universität Erlangen, Friedrich-Alexander-Universität Erlangen-Nürmberg, 91054 Erlangen, Germany; Department of Neurosurgery (J.H.), Eberhard Karls University Tübingen, 72076 Tübingen, Germany; Faculty of Medicine (V.P.), University of Belgrade, and Clinic of Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center, University of Belgrade, 11 000 Belgrade, Serbia; Second Department of Medicine (M.Tót.), Faculty of Medicine, Semmelweis University, 1088 Budapest, Hungary; and School of Life Science and Technology (A.I.A.), Bandung Institute of Technology, 40132 Bandung, Ind

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http://dx.doi.org/10.1210/jc.2015-1453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490309PMC
July 2015

FKBPs and the Akt/mTOR pathway.

Cell Cycle 2013 Aug 1;12(15):2366-70. Epub 2013 Jul 1.

Max Planck Institute of Psychiatry; Munich, Germany.

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http://dx.doi.org/10.4161/cc.25508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841315PMC
August 2013

Somatostatin receptors: from signaling to clinical practice.

Front Neuroendocrinol 2013 Aug 18;34(3):228-52. Epub 2013 Jul 18.

Department of Endocrinology, Max Planck Institute of Psychiatry, Kraepelinstrasse 10, 80804 Munich, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S00913022130003
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http://dx.doi.org/10.1016/j.yfrne.2013.07.005DOI Listing
August 2013

Sirt1 inhibits the transcription factor CREB to regulate pituitary growth hormone synthesis.

FASEB J 2013 Apr 4;27(4):1561-71. Epub 2013 Jan 4.

Department of Endocrinology, Max Planck Institute of Psychiatry, Munich, Germany.

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http://dx.doi.org/10.1096/fj.12-220129DOI Listing
April 2013

A general overview on pituitary tumorigenesis.

Ann Endocrinol (Paris) 2012 Apr 26;73(2):71-2. Epub 2012 Apr 26.

Department of Endocrinology, Max Planck Institute of Psychiatry, Munich, Germany.

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http://dx.doi.org/10.1016/j.ando.2012.04.003DOI Listing
April 2012

Effect of SOM230 (pasireotide) on corticotropic cells: action in dogs with Cushing's disease.

Neuroendocrinology 2011 28;94(2):124-36. Epub 2011 Apr 28.

Unidad de Endocrinología, Hospital Escuela, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1159/000327429DOI Listing
January 2012

The SHP-1 protein tyrosine phosphatase negatively modulates Akt signaling in the ghrelin/GHSR1a system.

Mol Biol Cell 2011 Nov 7;22(21):4182-91. Epub 2011 Sep 7.

Área de Endocrinología Molecular y Celular, Instituto de Investigación Sanitaria de Santiago, Hospital Clinico Universitario de Santiago, Servicio Gallego de Salud, 15706 Santiago de Compostela, Spain.

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http://dx.doi.org/10.1091/mbc.E11-04-0373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204078PMC
November 2011

Levels of p27 sensitize to dual PI3K/mTOR inhibition.

Mol Cancer Ther 2011 Aug 6;10(8):1450-9. Epub 2011 Jun 6.

Institute of Pathology, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0188DOI Listing
August 2011

ZAC1 target genes and pituitary tumorigenesis.

Mol Cell Endocrinol 2010 Sep 1;326(1-2):60-5. Epub 2010 Feb 1.

Max Planck Institute of Psychiatry, Department of Endocrinology, Kraepelinstrasse 10, 80804 Munich, Germany.

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http://dx.doi.org/10.1016/j.mce.2010.01.033DOI Listing
September 2010

Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis.

Cancer Res 2010 Jul 29;70(14):6026-35. Epub 2010 Jun 29.

School of Medicine and Department of Urology, Helen Diller Family Comprehensive Center, University of California, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-4730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913864PMC
July 2010

NOD2 receptors in adenopituitary folliculostellate cells: expression and function.

J Endocrinol 2009 Oct 16;203(1):111-22. Epub 2009 Jul 16.

Department of Endocrinology, Max Planck Institute of Psychiatry, Kraepelinstrasse 2-10, 80804 Munich, Germany.

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http://dx.doi.org/10.1677/JOE-09-0113DOI Listing
October 2009

Mammalian target of rapamycin inhibitors rapamycin and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro.

Endocr Relat Cancer 2009 Sep 9;16(3):1017-27. Epub 2009 Jun 9.

Institute of Endocrinology and Metabolism and Felsenstein Medical Research Center, Rabin Medical Center, Beilinson Campus, Petach Tikva 49100, Israel.

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http://dx.doi.org/10.1677/ERC-08-0269DOI Listing
September 2009

Obestatin stimulates Akt signalling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation.

Endocr Relat Cancer 2009 Jun 19;16(2):599-611. Epub 2009 Jan 19.

Laboratorio de Endocrinología Molecular y Celular, Instituto de Investigaciones Sanitarias, Complejo Hospitalario Universitario de Santiago (CHUS), 15706 Santiago de Compostela, Spain.

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http://dx.doi.org/10.1677/ERC-08-0192DOI Listing
June 2009

Modulation of growth hormone and prolactin secretion in Trypanosoma cruzi-infected mammosomatotrophic cells.

Neuroimmunomodulation 2009 27;16(3):208-12. Epub 2009 Feb 27.

Laboratory of Thymus Research, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1159/000205513DOI Listing
June 2009

c-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and -dependent mechanisms.

PLoS One 2009 5;4(3):e4686. Epub 2009 Mar 5.

Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigaciones Sanitarias, Complejo Hospitalario Universitario de Santiago (CHUS), Santiago de Compostela, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004686PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650409PMC
June 2009

Interferon-gamma inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel janus kinases-signal transducer and activator of transcription 1/nuclear factor-kappa B inhibitory signaling pathway.

J Endocrinol 2008 Nov 20;199(2):177-89. Epub 2008 Aug 20.

Department of Neuroendocrinology, Department of Molecular Neurogenetics Department of Inflammatory Disorders of the CNS at the Max Planck Institute of Psychiatry, Munich 80804, Germany.

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http://dx.doi.org/10.1677/JOE-08-0011DOI Listing
November 2008

Orexin-A inhibits glucagon secretion and gene expression through a Foxo1-dependent pathway.

Endocrinology 2008 Apr 27;149(4):1618-26. Epub 2007 Dec 27.

Endokrinologie, Diabetes, und Stoffwechsel Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1210/en.2007-1257DOI Listing
April 2008

Pituitary action of cytokines: focus on BMP-4 and gp130 family.

Neuroendocrinology 2007 28;85(2):94-100. Epub 2007 Feb 28.

Laboratorio de Fisiología y Biología Molecular, Departamento de Fisiología y Biología Molecular y Celular, FCEN, Universidad de Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1159/000100428DOI Listing
June 2007

Bone morphogenetic protein-4 control of pituitary pathophysiology.

Front Horm Res 2006 ;35:22-31

Laboratorio de Fisiología y Biología Molecular, Departamento de Fisiología, Biología Molecular y Celular, FCEN, Universidad de Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1159/000094262DOI Listing
October 2006

Retinoic acid as a novel medical therapy for Cushing's disease in dogs.

Endocrinology 2006 Sep 1;147(9):4438-44. Epub 2006 Jun 1.

Unidad de Endocrinología, Hospital Escuela, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina.

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http://dx.doi.org/10.1210/en.2006-0414DOI Listing
September 2006

Hypothalamus-pituitary-adrenal axis during Trypanosoma cruzi acute infection in mice.

J Neuroimmunol 2006 Apr 21;173(1-2):12-22. Epub 2006 Feb 21.

Laboratory on Thymus Research, Department of Immunology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Ave. Brasil 4365, Manguinhos- 21045-900, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1016/j.jneuroim.2005.08.015DOI Listing
April 2006

Bone morphogenetic protein-4 inhibits corticotroph tumor cells: involvement in the retinoic acid inhibitory action.

Endocrinology 2006 Jan 29;147(1):247-56. Epub 2005 Sep 29.

Laboratorio de Fisiología y Biología Molecular, Departemento de Fisiología, Biología Molecular y Celular, Facultad Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Argentina.

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http://dx.doi.org/10.1210/en.2005-0958DOI Listing
January 2006

Expression and function of sonic hedgehog pathway components in pituitary adenomas: evidence for a direct role in hormone secretion and cell proliferation.

J Clin Endocrinol Metab 2005 Dec 13;90(12):6687-94. Epub 2005 Sep 13.

Department of Endocrinology, Max-Planck Institute of Psychiatry, Munich, Germany.

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http://dx.doi.org/10.1210/jc.2005-1014DOI Listing
December 2005

Sonic hedgehog regulates CRH signal transduction in the adult pituitary.

FASEB J 2005 Feb 30;19(2):281-3. Epub 2004 Nov 30.

Max-Planck Institute of Psychiatry, Kraepelinstrasse 10, Munich 80804, Germany.

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http://dx.doi.org/10.1096/fj.04-2138fjeDOI Listing
February 2005