Marie-Laure Yaspo

Marie-Laure Yaspo

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Marie-Laure Yaspo

Marie-Laure Yaspo

Publications by authors named "Marie-Laure Yaspo"

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55Publications

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5-Fluorouracil treatment induces characteristic T>G mutations in human cancer.

Nat Commun 2019 Oct 8;10(1):4571. Epub 2019 Oct 8.

Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-12594-8DOI Listing
October 2019

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.

Cancer Cell 2018 12;34(6):996-1011.e8

Finsen Laboratory, Rigshospitalet, DK-2200, Copenhagen, Denmark; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, DK-2200, Copenhagen, Denmark; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69120 Heidelberg, Germany; Charité Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.10.016DOI Listing
December 2018

Cancer Precision Medicine: Why More Is More and DNA Is Not Enough.

Public Health Genomics 2017 9;20(2):70-80. Epub 2017 Jun 9.

Alacris Theranostics GmbH, Berlin, Germany.

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http://dx.doi.org/10.1159/000477157DOI Listing
April 2018

Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes.

Genome Med 2018 04 27;10(1):34. Epub 2018 Apr 27.

Otto Warburg Laboratory Gene Regulation and Systems Biology of Cancer, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1186/s13073-018-0542-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921987PMC
April 2018

The whole-genome landscape of medulloblastoma subtypes.

Nature 2017 07;547(7663):311-317

Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature22973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905700PMC
July 2017

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.

Cell 2016 11;167(5):1398-1414.e24

Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, Strangeways Research Laboratory, University of Cambridge, Wort's Causeway, Cambridge CB1 8RN, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674163144
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http://dx.doi.org/10.1016/j.cell.2016.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119954PMC
November 2016

Human Lineage-Specific Transcriptional Regulation through GA-Binding Protein Transcription Factor Alpha (GABPa).

Mol Biol Evol 2016 05 26;33(5):1231-44. Epub 2016 Jan 26.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany

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http://dx.doi.org/10.1093/molbev/msw007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839217PMC
May 2016

ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells.

PLoS One 2015 13;10(4):e0122518. Epub 2015 Apr 13.

IFOM (FIRC Institute of Molecular Oncology), IFOM-IEO-Campus, Milan, Italy; Department of Experimental Cardiology, Russian Cardiology Research and Production Complex, Moscow, Russia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122518PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395233PMC
January 2016

The direction of cross affects [corrected] obesity after puberty in male but not female offspring.

BMC Genomics 2015 Nov 6;16:904. Epub 2015 Nov 6.

Albrecht Daniel Thaer-Institut für Agrar- und Gartenbauwissenschaften, Humboldt-Universität zu Berlin, Invalidenstraße 42, D-10115, Berlin, Germany.

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http://dx.doi.org/10.1186/s12864-015-2164-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636810PMC
November 2015

Erratum to: 'The direction of cross affects obesity after puberty in male but not female offspring'.

BMC Genomics 2015 Nov 30;16(1):1018. Epub 2015 Nov 30.

Albrecht Daniel Thaer-Institut für Agrar- und Gartenbauwissenschaften, Humboldt-Universität zu Berlin, Invalidenstraße 42, Berlin, D-10115, Germany.

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http://dx.doi.org/10.1186/s12864-015-2204-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665910PMC
November 2015

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.

Nat Genet 2015 Sep 27;47(9):1020-1029. Epub 2015 Jul 27.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1038/ng.3362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603357PMC
September 2015

Network and systems biology: essential steps in virtualising drug discovery and development.

Drug Discov Today Technol 2015 Aug 8;15:33-40. Epub 2015 Aug 8.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany; Dahlem Centre for Genome Research and Medical Systems Biology, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ddtec.2015.07.002DOI Listing
August 2015

The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells.

PLoS One 2014 5;9(5):e92596. Epub 2014 May 5.

Institute of Pathology - University Hospital Berlin, Berlin, Germany; Laboratory of Functional Genomics (LFGC) - University Hospital Berlin, Berlin, Germany; Comprehensive Cancer Center Charité - University Hospital Berlin, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092596PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010406PMC
June 2015

ARH-seq: identification of differential splicing in RNA-seq data.

Nucleic Acids Res 2014 Aug 11;42(14):e110. Epub 2014 Jun 11.

Max-Planck-Institute for Molecular Genetics, Department of Vertebrate Genomics, Ihnestrasse 63-73, 14195 Berlin, Germany

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http://dx.doi.org/10.1093/nar/gku495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132698PMC
August 2014

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.

Nature 2014 Jul 22;511(7510):428-34. Epub 2014 Jun 22.

1] Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany [2] Department of Pediatric Oncology, Hematology & Immunology, Heidelberg University Hospital, Im Neuenheimer Feld 430, Heidelberg 69120, Germany.

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http://www.abta.org/resources/enhancers-hijacking-activates.
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http://www.nature.com/doifinder/10.1038/nature13379
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http://dx.doi.org/10.1038/nature13379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201514PMC
July 2014

Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation.

Sci Signal 2014 May 13;7(325):rs3. Epub 2014 May 13.

The David and Inez Myers Laboratory for Cancer Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1126/scisignal.2005032DOI Listing
May 2014

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.

Nat Genet 2013 Aug 30;45(8):927-32. Epub 2013 Jun 30.

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://pubman.mpdl.mpg.de/pubman/item/escidoc:1982973/compon
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http://www.nature.com/doifinder/10.1038/ng.2682
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http://dx.doi.org/10.1038/ng.2682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951336PMC
August 2013

Dissecting the genomic complexity underlying medulloblastoma.

Nature 2012 Aug;488(7409):100-5

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1038/nature11284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662966PMC
August 2012

A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods.

Biochem Biophys Res Commun 2012 Jun 15;422(4):643-6. Epub 2012 May 15.

Max Planck Institute for Molecular Genetics, Ihnestr. 73, D-14195 Berlin, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1200920
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http://dx.doi.org/10.1016/j.bbrc.2012.05.043DOI Listing
June 2012

Matrin 3 binds and stabilizes mRNA.

PLoS One 2011 17;6(8):e23882. Epub 2011 Aug 17.

The David and Inez Myers Laboratory for Cancer Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023882PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157474PMC
February 2012

A high-resolution anatomical atlas of the transcriptome in the mouse embryo.

PLoS Biol 2011 Jan 18;9(1):e1000582. Epub 2011 Jan 18.

Telethon Institute of Genetics and Medicine, Naples, Italy.

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http://digital.csic.es/bitstream/10261/52826/1/A%20High-Reso
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http://dx.plos.org/10.1371/journal.pbio.1000582
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http://dx.doi.org/10.1371/journal.pbio.1000582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022534PMC
January 2011

Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters.

Nucleic Acids Res 2010 Oct 21;38(18):6112-23. Epub 2010 May 21.

Department for Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1093/nar/gkq402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952857PMC
October 2010

Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments.

Nucleic Acids Res 2010 Jun 11;38(10):e112. Epub 2010 Feb 11.

Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Ihnestr 73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1093/nar/gkq041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879520PMC
June 2010

An efficient and economic enhancer mix for PCR.

Biochem Biophys Res Commun 2006 Sep 5;347(3):747-51. Epub 2006 Jul 5.

Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2006.06.151DOI Listing
September 2006

Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells.

Stem Cells 2005 Nov-Dec;23(10):1514-25. Epub 2005 Aug 4.

Max-Planck Institute for Molecular Genetics (Department of Vertebrate Genomics), Ihnestrasse 73, D-14195 Berlin, Germany.

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http://dx.doi.org/10.1634/stemcells.2005-0113DOI Listing
March 2006

A gene expression map of human chromosome 21 orthologues in the mouse.

Nature 2002 Dec;420(6915):586-90

Skirball Institute, Developmental Genetics Program and Department of Cell Biology, New York University School of Medicine, 540 First Avenue, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/nature01270DOI Listing
December 2002