Publications by authors named "Marie Wahren-Herlenius"

100Publications

Learning from similarities between vaccine responses and SLE.

Nat Rev Rheumatol 2020 07;16(7):355-356

Department of Medical Sciences, Rheumatology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1038/s41584-020-0421-5DOI Listing
July 2020

Increased risk of multiple myeloma in primary Sjögren's syndrome is limited to individuals with Ro/SSA and La/SSB autoantibodies.

Ann Rheum Dis 2020 02 6;79(2):307-308. Epub 2019 Nov 6.

Division of Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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http://dx.doi.org/10.1136/annrheumdis-2019-216287DOI Listing
February 2020

Innate immunity and interferons in the pathogenesis of Sjögren's syndrome.

Rheumatology (Oxford) 2019 Feb 15. Epub 2019 Feb 15.

Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1093/rheumatology/key360DOI Listing
February 2019

An update on the role of type I interferons in systemic lupus erythematosus and Sjögren's syndrome.

Curr Opin Rheumatol 2018 09;30(5):471-481

Department of Medical Sciences, Science for Life Laboratory, Rheumatology, Uppsala University, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1097/BOR.0000000000000524DOI Listing
September 2018

Corrigendum to "Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome" [Clin. Immunol. 168 (2016) 25-29].

Clin Immunol 2018 02 7;187:137-138. Epub 2017 Dec 7.

Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA; Department of Pathology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Department of Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Medical Service, Department of Veterans Affairs Medical Center, Oklahoma City, OK, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2017.11.012DOI Listing
February 2018

Sex influences eQTL effects of SLE and Sjögren's syndrome-associated genetic polymorphisms.

Biol Sex Differ 2017 10 25;8(1):34. Epub 2017 Oct 25.

Unit of Experimental Rheumatology, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13293-017-0153-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657123PMC
October 2017

Augmented Th17 differentiation in Trim21 deficiency promotes a stable phenotype of atherosclerotic plaques with high collagen content.

Cardiovasc Res 2018 01;114(1):158-167

Unit of Experimental Rheumatology, Department of Medicine, Karolinska Insititutet, Center for Molecular Medicine L8:04, Karolinska University Hospital, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1093/cvr/cvx181DOI Listing
January 2018

Factors influencing fetal cardiac conduction in anti-Ro/SSA-positive pregnancies.

Rheumatology (Oxford) 2017 10;56(10):1755-1762

Experimental Rheumatology Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1093/rheumatology/kex263DOI Listing
October 2017

Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.

PLoS Genet 2017 Jun 22;13(6):e1006820. Epub 2017 Jun 22.

Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501660PMC
June 2017

Difference in clinical presentation between women and men in incident primary Sjögren's syndrome.

Biol Sex Differ 2017 12;8:16. Epub 2017 May 12.

Unit of Experimental Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13293-017-0137-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427625PMC
April 2018

TRIM21 is important in the early phase of inflammation in the imiquimod-induced psoriasis-like skin inflammation mouse model.

Exp Dermatol 2017 08 19;26(8):713-720. Epub 2017 Feb 19.

Department of Dermatology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/exd.13269DOI Listing
August 2017

Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.

Clin Immunol 2016 07 22;168:25-29. Epub 2016 Apr 22.

Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA; Department of Pathology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Department of Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Medical Service, Department of Veterans Affairs Medical Center, Oklahoma City, OK, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940221PMC
July 2016

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Arthritis Rheumatol 2016 05;68(5):1290-1300

College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

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http://dx.doi.org/10.1002/art.39560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019501PMC
May 2016

The Expression of BAFF Is Controlled by IRF Transcription Factors.

J Immunol 2016 Jan 20;196(1):91-6. Epub 2015 Nov 20.

Unit of Experimental Rheumatology, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, SE-171 76 Stockholm, Sweden;

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http://dx.doi.org/10.4049/jimmunol.1501061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683359PMC
January 2016

Outcome in 212 anti-Ro/SSA-positive pregnancies and population-based incidence of congenital heart block.

Acta Obstet Gynecol Scand 2016 Jan 26;95(1):98-105. Epub 2015 Oct 26.

Pediatric Cardiology Unit, Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1111/aogs.12785DOI Listing
January 2016

Update on the immunobiology of Sjögren's syndrome.

Curr Opin Rheumatol 2015 Sep;27(5):468-75

Unit of Experimental Rheumatology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1097/BOR.0000000000000195DOI Listing
September 2015

Pathogenesis of the Novel Autoimmune-Associated Long-QT Syndrome.

Circulation 2015 Jul 20;132(4):230-40. Epub 2015 May 20.

From Cardiovascular Research Program, VA New York Harbor Healthcare System, Brooklyn (Y.Y., U.S., F.F., K.S., Z.L., Y.Q., N.E.-S., M.M.H., X.-C.J., M.B.); Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Italy (M.C., P.-L.C., F.L.-P., P.-E.L.); Departments of Medicine, Cell Biology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn (U.S., F.F., Z.L., Y.Q., M.M.H., X.-C.J., M.B.); Knight Cardiovascular Institute, Oregon Health & Science University, Portland (Z.Z.); Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin, Madison (C.J.); Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York (E.A.S.); Unit of Experimental Rheumatology, Department of Medicine, Karolinska Institute, Stockholm, Sweden (M.W.-H.); Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec, Laval University, Quebec City, Canada (M.C.); and Department of Medicine, New York University School of Medicine, New York (M.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.009800DOI Listing
July 2015

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.

Hum Mol Genet 2015 Jan 8;24(2):582-96. Epub 2014 Sep 8.

Division of Rheumatology, Center for Autoimmune Genomics and Etiology and US Department of Veterans Affairs Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1093/hmg/ddu455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275071PMC
January 2015

Interferon beta treatment of multiple sclerosis increases serum interleukin-7.

Mult Scler 2014 Nov 12;20(13):1727-36. Epub 2014 May 12.

Center for Molecular Medicine, Karolinska Institutet, SE-17176 Stockholm, Sweden

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http://dx.doi.org/10.1177/1352458514532700DOI Listing
November 2014

Molecular mechanisms of congenital heart block.

Exp Cell Res 2014 Jul 13;325(1):2-9. Epub 2014 Jan 13.

Unit of Experimental Rheumatology, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.01.003DOI Listing
July 2014

Late development of complete atrioventricular block may be immune mediated and congenital in origin.

Acta Paediatr 2014 Mar 30;103(3):275-81. Epub 2013 Dec 30.

Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/apa.12483DOI Listing
March 2014

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.

Nat Genet 2013 Nov 6;45(11):1284-92. Epub 2013 Oct 6.

1] Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA. [2] Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

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http://dx.doi.org/10.1038/ng.2792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867192PMC
November 2013

A possible genetic association with chronic fatigue in primary Sjögren's syndrome: a candidate gene study.

Rheumatol Int 2014 Feb 3;34(2):191-7. Epub 2013 Sep 3.

Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Pb. 8100 Forus, 4068, Stavanger, Norway,

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http://dx.doi.org/10.1007/s00296-013-2850-9DOI Listing
February 2014

Immunopathogenic mechanisms of systemic autoimmune disease.

Lancet 2013 Aug;382(9894):819-31

Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/S0140-6736(13)60954-XDOI Listing
August 2013

Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factors.

J Immunol 2013 Oct 23;191(7):3753-63. Epub 2013 Aug 23.

Unit of Rheumatology, Department of Medicine, Karolinska Institutet, SE-171 76 Stockholm, Sweden;

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http://dx.doi.org/10.4049/jimmunol.1202341DOI Listing
October 2013

Genetic associations to germinal centre formation in primary Sjogren's syndrome.

Ann Rheum Dis 2014 Jun 20;73(6):1253-8. Epub 2013 Apr 20.

Broegelmann Research Laboratory, The Gade Institute, University of Bergen, , Bergen, Norway.

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http://dx.doi.org/10.1136/annrheumdis-2012-202500DOI Listing
June 2014

Long-term growth of children with autoantibody-mediated congenital heart block.

Acta Paediatr 2013 Jul 22;102(7):718-26. Epub 2013 Apr 22.

Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/apa.12248DOI Listing
July 2013

Neurodevelopment in children with and without congenital heart block born to anti-Ro/SSA-positive mothers.

Acta Paediatr 2013 Jan 1;102(1):40-6. Epub 2012 Nov 1.

Department of Medicine, Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/apa.12049DOI Listing
January 2013

IL-17: a new actor in IFN-driven systemic autoimmune diseases.

Eur J Immunol 2012 Sep;42(9):2274-84

Unit of Rheumatology, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/eji.201242653DOI Listing
September 2012

Congenital heart block: evidence for a pathogenic role of maternal autoantibodies.

Arthritis Res Ther 2012 Apr 26;14(2):208. Epub 2012 Apr 26.

Rheumatology Unit, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1186/ar3787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446439PMC
April 2012

The immunobiology of Ro52 (TRIM21) in autoimmunity: a critical review.

J Autoimmun 2012 Aug 7;39(1-2):77-82. Epub 2012 Mar 7.

Rheumatology Unit, Department of Medicine, Center for Molecular Medicine L8:04, Karolinska Institutet, 17176 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jaut.2012.01.014DOI Listing
August 2012

Progression to first-degree heart block in preschool children exposed in utero to maternal anti-SSA/Ro52 autoantibodies.

Acta Paediatr 2012 May 16;101(5):488-93. Epub 2012 Jan 16.

Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1651-2227.2011.02563.xDOI Listing
May 2012

Ro52 autoantibody-positive women's experience of being pregnant and giving birth to a child with congenital heart block.

Midwifery 2013 Jan 10;29(1):18-23. Epub 2011 Dec 10.

Department of Medicine, Karolinska Institutet, S-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.midw.2011.10.008DOI Listing
January 2013

The complexity of Sjögren's syndrome: novel aspects on pathogenesis.

Immunol Lett 2011 Dec 12;141(1):1-9. Epub 2011 Jul 12.

Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1016/j.imlet.2011.06.007DOI Listing
December 2011

Gene-environment interaction in induction of autoimmunity.

Semin Immunol 2011 Apr 12;23(2):65-6. Epub 2011 Mar 12.

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http://dx.doi.org/10.1016/j.smim.2011.02.002DOI Listing
April 2011

The experiences of pregnancy in women with SSA/Ro52 autoantibodies.

Musculoskeletal Care 2010 Dec 12;8(4):215-23. Epub 2010 Oct 12.

Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1002/msc.189DOI Listing
December 2010

Immunological contribution to the pathogenesis of congenital heart block.

Scand J Immunol 2010 Sep;72(3):171-2

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http://dx.doi.org/10.1111/j.1365-3083.2010.02446.xDOI Listing
September 2010

Serologic follow-up of children born to mothers with Ro/SSA autoantibodies.

Lupus 2009 Aug;18(9):792-8

Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/0961203309103188DOI Listing
August 2009

High Ro52 expression in spontaneous and UV-induced cutaneous inflammation.

J Invest Dermatol 2009 Aug 5;129(8):2000-10. Epub 2009 Feb 5.

Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/jid.2008.453DOI Listing
August 2009

The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide.

Exp Cell Res 2008 Dec 25;314(20):3605-13. Epub 2008 Sep 25.

Rheumatology Unit, Department of Medicine, CMM L8:04, Karolinska Institutet, SE-171 76 Stockholm, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S001448270800360
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http://dx.doi.org/10.1016/j.yexcr.2008.09.011DOI Listing
December 2008

Minor salivary gland immunohistology in the diagnosis of primary Sjögren's syndrome.

J Oral Pathol Med 2009 Mar 12;38(3):282-8. Epub 2008 Sep 12.

Department of Medicine, Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1600-0714.2008.00697.xDOI Listing
March 2009

Clinical follow-up of 102 anti-Ro/SSA-positive patients with dermatological manifestations.

Acta Derm Venereol 2008 ;88(4):370-5

Department of Clinical Sciences, Division of Dermatology, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.2340/00015555-0473DOI Listing
November 2008

Outcome and growth of infants fetally exposed to heart block-associated maternal anti-Ro52/SSA autoantibodies.

Pediatrics 2008 Apr;121(4):e803-9

Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1542/peds.2007-1659DOI Listing
April 2008

Detection of antigen specific B-cells in tissues.

Methods Mol Med 2007 ;136:19-24

Rheumatology Unit, Department of Medicine, Karolinska Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1007/978-1-59745-402-5_2DOI Listing
December 2007

Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis.

Arthritis Res Ther 2006 ;8(6):R167

Rheumatology Unit, Department of Medicine Solna, Karolinska Institutet, CMM L8:04, Karolinska Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1186/ar2076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794511PMC
February 2007

Specificity and effector mechanisms of autoantibodies in congenital heart block.

Curr Opin Immunol 2006 Dec 29;18(6):690-6. Epub 2006 Sep 29.

Rheumatology Unit, Department of Medicine, Karolinska Institutet, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.coi.2006.09.012DOI Listing
December 2006

The Sjogren's syndrome-associated autoantigen Ro52 is an E3 ligase that regulates proliferation and cell death.

J Immunol 2006 May;176(10):6277-85

Rheumatology Unit, Department of Medicine, Karolinska Institutet at Danderyd Hospital, Karolinska Institutet, S-17176 Stockholm, Sweden.

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http://dx.doi.org/10.4049/jimmunol.176.10.6277DOI Listing
May 2006

Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52.

J Biol Chem 2005 Sep 17;280(39):33250-61. Epub 2005 Jun 17.

Molecular Biotechnology, IFM, Campus Valla, Linköping University, S-581 83 Linköping, Sweden.

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http://dx.doi.org/10.1074/jbc.M503066200DOI Listing
September 2005

Structural, functional and immunologic characterization of folded subdomains in the Ro52 protein targeted in Sjögren's syndrome.

Mol Immunol 2006 Feb;43(6):588-98

Rheumatology Unit, Department of Medicine, CMM L8:04, Karolinska Institutet, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.molimm.2005.04.013DOI Listing
February 2006

Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands.

Nat Genet 2005 Feb 16;37(2):125-7. Epub 2005 Jan 16.

Department of Genetics and Pathology, Uppsala University, The Rudbeck laboratory, SE-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1038/ng1507DOI Listing
February 2005