Marie Jose Goumans

Marie Jose Goumans

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Marie Jose Goumans

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Pathogenic effect of a TGFBR1 mutation in a family with Loeys-Dietz syndrome.

Mol Genet Genomic Med 2019 Oct 1;7(10):e00943. Epub 2019 Sep 1.

Department of Clinical Genetics, Amsterdam University Medical Centre, VUMC, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/mgg3.943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785444PMC
October 2019

Injectable Supramolecular Ureidopyrimidinone Hydrogels Provide Sustained Release of Extracellular Vesicle Therapeutics.

Adv Healthc Mater 2019 Oct 26;8(20):e1900847. Epub 2019 Sep 26.

Department of Cardiology, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, 3584, The Netherlands.

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http://dx.doi.org/10.1002/adhm.201900847DOI Listing
October 2019

Stress-induced remodelling of the mitral valve: a model for leaflet thickening and superimposed tissue formation in mitral valve disease.

Cardiovasc Res 2019 Sep 8. Epub 2019 Sep 8.

Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvz204DOI Listing
September 2019

Reply to: More Insights into the Association Between RVX-208 and Pulmonary Arterial Hypertension.

Am J Respir Crit Care Med 2019 Sep 27. Epub 2019 Sep 27.

CRIUCPQ, Quebec, Quebec, Canada.

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http://dx.doi.org/10.1164/rccm.201909-1800LEDOI Listing
September 2019

The role of hemodynamics in bicuspid aortopathy: a histopathologic study.

Cardiovasc Pathol 2019 Jul - Aug;41:29-37. Epub 2019 Apr 1.

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.carpath.2019.03.002DOI Listing
July 2019

Immunofluorescent Visualization of BMP Signaling Activation on Paraffin-Embedded Tissue Sections.

Methods Mol Biol 2019 ;1891:191-200

Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.

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http://link.springer.com/10.1007/978-1-4939-8904-1_14
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http://dx.doi.org/10.1007/978-1-4939-8904-1_14DOI Listing
June 2019

Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5.

Stem Cell Reports 2019 05 4;12(5):906-919. Epub 2019 Apr 4.

Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), 1105 BA Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522954PMC
May 2019

Cardiac Progenitor Cell-Derived Extracellular Vesicles Reduce Infarct Size and Associate with Increased Cardiovascular Cell Proliferation.

J Cardiovasc Transl Res 2019 02 19;12(1):5-17. Epub 2018 Nov 19.

Laboratory of Cardiovascular Cell Biology, Department of Cell and Chemical Biology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s12265-018-9842-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394631PMC
February 2019

Pulmonary Arterial Hypertension and Hereditary Haemorrhagic Telangiectasia.

Int J Mol Sci 2018 Oct 17;19(10). Epub 2018 Oct 17.

Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.

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http://www.mdpi.com/1422-0067/19/10/3203
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http://dx.doi.org/10.3390/ijms19103203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213989PMC
October 2018

TGF-β and BMPR2 Signaling in PAH: Two Black Sheep in One Family.

Int J Mol Sci 2018 Aug 31;19(9). Epub 2018 Aug 31.

Department of Cell and Chemical Biology, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.

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http://www.mdpi.com/1422-0067/19/9/2585
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http://dx.doi.org/10.3390/ijms19092585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164161PMC
August 2018

The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens.

J Vis Exp 2018 04 24(134). Epub 2018 Apr 24.

Department of Molecular Cell Biology, Leiden University Medical Center;

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http://dx.doi.org/10.3791/57370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100756PMC
April 2018

TGF-β Signaling in Control of Cardiovascular Function.

Cold Spring Harb Perspect Biol 2018 02 1;10(2). Epub 2018 Feb 1.

Department of Molecular Cell Biology and Cancer Genomics Centre Netherlands, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

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http://cshperspectives.cshlp.org/lookup/doi/10.1101/cshpersp
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http://dx.doi.org/10.1101/cshperspect.a022210DOI Listing
February 2018

Bone Morphogenetic Proteins in Vascular Homeostasis and Disease.

Cold Spring Harb Perspect Biol 2018 02 1;10(2). Epub 2018 Feb 1.

Institut National de la Santé et de la Recherche Mécale (INSERM), U1036, 38000 Grenoble, France.

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http://dx.doi.org/10.1101/cshperspect.a031989DOI Listing
February 2018

MicroRNA-221/222 Family Counteracts Myocardial Fibrosis in Pressure Overload-Induced Heart Failure.

Hypertension 2018 02 18;71(2):280-288. Epub 2017 Dec 18.

From the Department of Cardiology (R.V., T.P., R.v.L., W.V., M.H., L.J.d.W., S.H., B.S.), Department of Physiology (C.M., F.A.v.N., M.v.B.), and Department of Internal Medicine (M.B.), CARIM School for Cardiovascular Diseases, Maastricht University, The Netherlands; Program of Cardiovascular Diseases, Centre for Applied Medical Research, University of Navarra, Pamplona, Spain (F.J.B., J.D., A.G.); Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain (F.J.B., J.D., A.G.); CIBERCV, Carlos III Institute of Health, Madrid, Spain (F.J.B., J.D., A.G.); Department of Molecular Cell Biology, Leiden University Medical Biology Center, The Netherlands (T.v.H., M.J.G.); Department of Cardiology and Cardiac Surgery, University of Navarra Clinic, Pamplona, Spain (J.D.); Netherlands Heart Institute (ICIN), Utrecht; and Department of Cardiovascular Sciences, Centre for Molecular and Vascular Biology (CMVB), KU Leuven, Belgium (S.H.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10094DOI Listing
February 2018

The epicardium as a source of multipotent adult cardiac progenitor cells: Their origin, role and fate.

Pharmacol Res 2018 01 24;127:129-140. Epub 2017 Jul 24.

Department of Molecular Cell Biology, Leiden University Medical Center, P.O. Box 9600, Postzone S-1-P, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.phrs.2017.07.020DOI Listing
January 2018

Glycosylated Cell Surface Markers for the Isolation of Human Cardiac Progenitors.

Stem Cells Dev 2017 11 17;26(21):1552-1565. Epub 2017 Oct 17.

1 Department of Molecular Cell Biology, Leiden University Medical Center , Leiden, the Netherlands .

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http://dx.doi.org/10.1089/scd.2017.0048DOI Listing
November 2017

Thoracic Aortic Aneurysm Development in Patients with Bicuspid Aortic Valve: What Is the Role of Endothelial Cells?

Front Physiol 2017 30;8:938. Epub 2017 Nov 30.

Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, Netherlands.

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http://dx.doi.org/10.3389/fphys.2017.00938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714935PMC
November 2017

Higher functionality of extracellular vesicles isolated using size-exclusion chromatography compared to ultracentrifugation.

Nanomedicine 2017 Aug 30;13(6):2061-2065. Epub 2017 Mar 30.

Laboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2017.03.011DOI Listing
August 2017

Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair.

Circulation 2017 May 6;135(19):1832-1847. Epub 2017 Feb 6.

From Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Germany (M.T., J.E.H., P.B., S.S., T.M., M.-L.C.L., E.L., F.R., S.Z., E. Wettwer, W.-H.Z.); German Center for Cardiovascular Research (DZHK), partner site Göttingen, Germany (M.T., J.E.H., P.B., S.S., T.M., M.-L.C.L., E.L., F.R., S.Z., E. Wingender, W.A.L., W.-H.Z.); Institute of Bioinformatics, University Medical Center Göttingen, Germany (S.Z., E. Wingender); Stanford Cardiovascular Institute (J.R., M.W., J.D.G., J.C.W.) and Department of Radiology (J.D.G., J.C.W.), Molecular Imaging Program, Stanford University School of Medicine, CA; The Sohnis Laboratory for Cardiac Electrophysiology and Regenerative Medicine, Technion-Israel Institute of Technology, Haifa (I.K., L.G.); Institute of Pharmacology and Toxicology, Technical University Dresden, Germany (E. Wettwer, U.R.); University Medical Center Utrecht and Hubrecht Institute, The Netherlands (P.D., L.W.v.L.); Leiden University Medical Center, The Netherlands (M.J.G.); Clinic for Cardiology and Pneumology, University Medical Center Göttingen, Germany (S.K., K.T., G.H., W.A.L.); Center for Applied Technology, Beckman Research Institute, City of Hope, Duarte, CA (L.A.C.); Department of Cardiovascular Physiology, Institute of Physiology, Ruhr University Bochum, Bochum, Germany (A.U., W.A.L.); New Laura and Isaac Perlmutter Cancer Center at New York University Langone (T.A., B.N.); and McEwen Centre for Regenerative Medicine, Toronto, Canada (G.K.). The current address for Dr Hudson is Laboratory for Cardiac Regeneration, School of Biomedical Sciences, The University of Queensland, Australia.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501412PMC
May 2017

Mimicking Cardiac Fibrosis in a Dish: Fibroblast Density Rather than Collagen Density Weakens Cardiomyocyte Function.

J Cardiovasc Transl Res 2017 Apr 9;10(2):116-127. Epub 2017 Mar 9.

Department of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, Eindhoven, 5600 MB, the Netherlands.

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http://dx.doi.org/10.1007/s12265-017-9737-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437129PMC
April 2017

The Microvasculature: The Next Battlefield Where Transforming Growth Factor-β and Endoglin Draw Their Double-Edged Swords?

Arterioscler Thromb Vasc Biol 2017 01;37(1):10-12

From the Laboratory of Experimental Cardiology, Department of Cardiology and Laboratory of Clinical Chemistry, University Medical Center Utrecht, The Netherlands (G.P.); and Department of Molecular Cell Biology, Leiden University Medical Center, The Netherlands (M.J.G.).

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http://dx.doi.org/10.1161/ATVBAHA.116.308610DOI Listing
January 2017

Comparative transcriptomic analysis identifies genes differentially expressed in human epicardial progenitors and hiPSC-derived cardiac progenitors.

Physiol Genomics 2016 11 2;48(11):771-784. Epub 2016 Sep 2.

Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1152/physiolgenomics.00064.2016DOI Listing
November 2016

Human fetal and adult epicardial-derived cells: a novel model to study their activation.

Stem Cell Res Ther 2016 11 29;7(1):174. Epub 2016 Nov 29.

Department of Molecular Cell Biology, Leiden University Medical Center, P.O Box 9600, Postzone S-1-P, 2300RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1186/s13287-016-0434-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129650PMC
November 2016

Exosomes from Cardiomyocyte Progenitor Cells and Mesenchymal Stem Cells Stimulate Angiogenesis Via EMMPRIN.

Adv Healthc Mater 2016 10 29;5(19):2555-2565. Epub 2016 Aug 29.

Department of Cardiology, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, 3584CX, The Netherlands.

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http://dx.doi.org/10.1002/adhm.201600308DOI Listing
October 2016

Part and Parcel of the Cardiac Autonomic Nerve System: Unravelling Its Cellular Building Blocks during Development.

J Cardiovasc Dev Dis 2016 Sep 12;3(3). Epub 2016 Sep 12.

Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZC Leiden, The Netherlands.

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http://dx.doi.org/10.3390/jcdd3030028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715672PMC
September 2016

Cardiomyocyte progenitor cell mechanoresponse unrevealed: strain avoidance and mechanosome development.

Integr Biol (Camb) 2016 09;8(9):991-1001

Department of Biomedical Engineering, Eindhoven University of Technology, PO box 513, Groene Loper, Building 15, Gem-Zuid 4.117, 5600 MB Eindhoven, The Netherlands. and Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands.

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http://dx.doi.org/10.1039/c6ib00117cDOI Listing
September 2016

Response by van der Bruggen et al to Letter Regarding Article, "Bone Morphogenetic Protein Receptor Type 2 Mutation in Pulmonary Arterial Hypertension: A View on the Right Ventricle".

Circulation 2016 Aug;134(9):e117-8

From VU University Medical Center/Institute of Cardiovascular Research, Pulmonology, Amsterdam, the Netherlands (C.E.E.v.d.B., C.M.H., H.J.B., A.V.N., F.S.d.M.); and Leiden University Medical Center, Molecular Cell Biology, Leiden, the Netherlands (M.J.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024173DOI Listing
August 2016

Bone Morphogenetic Protein Receptor Type 2 Mutation in Pulmonary Arterial Hypertension: A View on the Right Ventricle.

Circulation 2016 May 16;133(18):1747-60. Epub 2016 Mar 16.

From Department of Pulmonology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands (C.E.E.V.D.B., C.M.H., P.T., O.A.S., N.R., A.V.N., H.J.B., F.S.d.M.); Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands (C.M.H., N.R., F.P.H., J.V.D.V., F.S.d.M.); Univ. Paris-Sud, Le Kremlin-Bicêtre, France (P.D., B.G., .M.H.); AP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France (P.D., B.G., M.H.); INSERM999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France (P.D., B.G., M.H.); Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands (A.C.H.); Department of Physics and Medical Technology, VU University Medical Center, Amsterdam, The Netherlands (J.T.M.); Department of Thoracic and Vascular Surgery and Heart-Lung Transplantation, Hôpital Marie-Lannelongue, Le Plessis Robinson, Paris-Sud University, France (O.M.); Department of Cardiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands (M.L.H.); and Department of Molecular Cell Biology, Laboratory of Experimental Cardiology, Leiden University Medical Center, Leiden, The Netherlands (M.-J.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020696DOI Listing
May 2016

Cardiac Stem Cell Treatment in Myocardial Infarction: A Systematic Review and Meta-Analysis of Preclinical Studies.

Circ Res 2016 Apr 17;118(8):1223-32. Epub 2016 Feb 17.

From the Department of Cardiology, Experimental Cardiology Laboratory, University Medical Center Utrecht, Utrecht, The Netherlands (P.P.Z., A.M.D.V., S.J.J.o.L., G.P.J.v.H., J.W.B., P.A.D., S.A.J.C., J.P.G.S.); Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands (A.M.D.V., M.-J.G.); Department of Clinical Neurosciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom (G.L.C., E.S.S., M.R.M.); Department of Nephrology & Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands (H.G.); ICIN, Netherlands Heart Institute, Utrecht, The Netherlands (P.A.D., S.A.J.C., J.P.G.S.); and UMC Utrecht Regenerative Medicine Center, University Medical Center Utrecht, Utrecht, The Netherlands (P.A.D., S.A.J.C., J.P.G.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.307676DOI Listing
April 2016

Inhibition of TGFβ type I receptor activity facilitates liver regeneration upon acute CCl4 intoxication in mice.

Arch Toxicol 2016 Feb 8;90(2):347-57. Epub 2015 Jan 8.

Department of Molecular and Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2333ZC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00204-014-1436-yDOI Listing
February 2016

Environmental Influences on Endothelial to Mesenchymal Transition in Developing Implanted Cardiovascular Tissue-Engineered Grafts.

Tissue Eng Part B Rev 2016 Feb 8;22(1):58-67. Epub 2015 Oct 8.

1 Department of Nephrology and Hypertension, University Medical Center Utrecht , Utrecht, The Netherlands .

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https://www.liebertpub.com/doi/10.1089/ten.teb.2015.0167
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http://dx.doi.org/10.1089/ten.TEB.2015.0167DOI Listing
February 2016

Targeting BMP signalling in cardiovascular disease and anaemia.

Nat Rev Cardiol 2016 Feb 13;13(2):106-20. Epub 2015 Oct 13.

Anaesthesia Centre for Critical Care Research, Department of Anaesthesia, Critical Care and Pain Medicine, 55 Fruit Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/nrcardio.2015.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886232PMC
February 2016

Regulatory RNAs controlling vascular (dys)function by affecting TGF-ß family signalling.

EXCLI J 2015 10;14:832-50. Epub 2015 Jul 10.

Department of Molecular Cell Biology, Cancer Genomics Centre Netherlands, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.17179/excli2015-423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743484PMC
February 2016

Measuring the primary cilium length: improved method for unbiased high-throughput analysis.

Cilia 2016 11;5. Epub 2016 Feb 11.

Department Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.

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http://www.ciliajournal.com/content/5/1/7
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http://dx.doi.org/10.1186/s13630-016-0028-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750300PMC
February 2016

Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors.

Clin Cancer Res 2016 Jan 15;22(1):96-106. Epub 2015 Sep 15.

Department of Molecular Cell Biology and Cancer Genomics Centre Netherlands, Leiden University Medical Center, Leiden, the Netherlands. Ludwig Institute for Cancer Research, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0743DOI Listing
January 2016

The roadmap of WT1 protein expression in the human fetal heart.

J Mol Cell Cardiol 2016 Jan 10;90:139-45. Epub 2015 Dec 10.

Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.12.008DOI Listing
January 2016

The epicardium as modulator of the cardiac autonomic response during early development.

J Mol Cell Cardiol 2015 Dec 23;89(Pt B):251-9. Epub 2015 Oct 23.

Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.10.025DOI Listing
December 2015

The Derivation of Primary Human Epicardium-Derived Cells.

Curr Protoc Stem Cell Biol 2015 Nov 4;35:2C.5.1-2C.5.12. Epub 2015 Nov 4.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/9780470151808.sc02c05s35DOI Listing
November 2015

Behavior of CMPCs in unidirectional constrained and stress-free 3D hydrogels.

J Mol Cell Cardiol 2015 Oct 14;87:79-91. Epub 2015 Aug 14.

Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands; Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.08.010DOI Listing
October 2015

Culturing Mouse Cardiac Valves in the Miniature Tissue Culture System.

J Vis Exp 2015 Oct 19(105):e52750. Epub 2015 Oct 19.

Department of Molecular Cell Biology, Leiden University Medical Center.

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http://dx.doi.org/10.3791/52750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692664PMC
October 2015

mAb C19 targets a novel surface marker for the isolation of human cardiac progenitor cells from human heart tissue and differentiated hESCs.

J Mol Cell Cardiol 2015 May 25;82:228-37. Epub 2015 Mar 25.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore; Department of Bioengineering, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.02.016DOI Listing
May 2015

Cardiac endothelial cells express Wilms' tumor-1: Wt1 expression in the developing, adult and infarcted heart.

J Mol Cell Cardiol 2015 Apr 11;81:127-35. Epub 2015 Feb 11.

Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.02.007DOI Listing
April 2015

Mononuclear cells and vascular repair in HHT.

Front Genet 2015 23;6:114. Epub 2015 Mar 23.

Department of Molecular Cell Biology, Leiden University Medical Center Leiden, Netherlands.

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http://dx.doi.org/10.3389/fgene.2015.00114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369645PMC
April 2015

SLUG is expressed in endothelial cells lacking primary cilia to promote cellular calcification.

Arterioscler Thromb Vasc Biol 2015 Mar 29;35(3):616-27. Epub 2015 Jan 29.

From the Department of Molecular Cell Biology, Cancer Genomics Centre Netherlands (G.S.-D., A.G.d.V., M.-J.G., P.t.D.), Department of Vascular Surgery (J.H.L., A.M.-S.) and Department of Anatomy and Embryology (M.C.D., C.V.M., B.P.H.), Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1161/ATVBAHA.115.305268DOI Listing
March 2015

Remodeling of the myocardium in early trabeculation and cardiac valve formation; a role for TGFβ2.

Int J Dev Biol 2013 ;57(11-12):853-63

Cardiovascular Research Institute, Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey, USA.

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http://www.intjdevbiol.com/paper.php?doi=130302bk
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http://dx.doi.org/10.1387/ijdb.130302bkDOI Listing
November 2014

Ascending aorta dilation in association with bicuspid aortic valve: a maturation defect of the aortic wall.

J Thorac Cardiovasc Surg 2014 Oct 25;148(4):1583-90. Epub 2014 Jan 25.

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2014.01.027DOI Listing
October 2014

The microRNA-15 family inhibits the TGFβ-pathway in the heart.

Cardiovasc Res 2014 Oct 7;104(1):61-71. Epub 2014 Aug 7.

Department of Experimental Cardiology, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands

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http://dx.doi.org/10.1093/cvr/cvu184DOI Listing
October 2014

A straightforward guide to the basic science behind cardiovascular cell-based therapies.

Heart 2014 Aug;100(15):1153-7

Department of Molecular Cell Biology and Center for Biomedical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1136/heartjnl-2014-305646DOI Listing
August 2014

A multistep procedure to prepare pre-vascularized cardiac tissue constructs using adult stem sells, dynamic cell cultures, and porous scaffolds.

Front Physiol 2014 3;5:210. Epub 2014 Jun 3.

Biomaterials Unit, International Center for Materials Nanoarchitectonics, National Institute for Materials Science Tsukuba, Japan ; International Clinical Research Center, Integrated Center of Cellular Therapy and Regenerative Medicine, St. Anne's University Hospital Brno, Czech Republic.

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http://dx.doi.org/10.3389/fphys.2014.00210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042082PMC
June 2014

Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling.

Nat Commun 2014 Mar 3;5:3388. Epub 2014 Mar 3.

1] Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China [2] Department of Molecular Cell Biology, Cancer Genomics Centre Netherlands and Centre for Biomedical Genetics, Leiden University Medical Center, Postbus 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1038/ncomms4388DOI Listing
March 2014

MicroRNA-1 enhances the angiogenic differentiation of human cardiomyocyte progenitor cells.

J Mol Med (Berl) 2013 Aug 27;91(8):1001-12. Epub 2013 Apr 27.

Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Heidelberglaan 100, room G02.523, 3584 CX, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00109-013-1017-1DOI Listing
August 2013

Cardiac regeneration: stem cells and beyond.

Curr Med Chem 2012 ;19(35):5993-6002

Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands.

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http://dx.doi.org/10.2174/092986712804485935DOI Listing
June 2013

Extraembryonic endoderm cells as a model of endoderm development.

Dev Growth Differ 2013 Apr 18;55(3):301-8. Epub 2013 Feb 18.

Department of Molecular and Cell Biology, Centre of Biomedical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/dgd.12036DOI Listing
April 2013

CD26 inhibition enhances perfusion recovery in ApoE-/-mice.

Curr Vasc Pharmacol 2013 Jan;11(1):21-8

Laboratory of Experimental Cardiology, University Medical Center Utrecht, G02.523, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

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January 2013

Reduced CD26 expression is associated with improved cardiac function after acute myocardial infarction: insights from the REPERATOR study.

J Mol Cell Cardiol 2012 Dec 9;53(6):899-905. Epub 2012 Sep 9.

University Medical Center, Division Heart & Lungs, Laboratory Experimental Cardiology, G02-523, Postbus 85500, 3508 GA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.yjmcc.2012.08.026DOI Listing
December 2012