Marianne Nygaard

Marianne Nygaard

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Marianne Nygaard

Marianne Nygaard

Publications by authors named "Marianne Nygaard"

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A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2019 Aug 27;138(2):237-250. Epub 2019 May 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02026-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501PMC
August 2019

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 Aug 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

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http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

Epigenetic signature of preterm birth in adult twins.

Clin Epigenetics 2018 27;10:87. Epub 2018 Jun 27.

1Epidemiology and Biostatistics, Department of Public Health, Faculty of Health Science, University of Southern Denmark, J. B. Winsløws Vej 9B, DK-5000 Odense, Denmark.

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http://dx.doi.org/10.1186/s13148-018-0518-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020425PMC
July 2019

Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.

Biogerontology 2019 Jun 28. Epub 2019 Jun 28.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J.B. Winsløws Vej 9B, 5000, Odense C, Denmark.

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http://dx.doi.org/10.1007/s10522-019-09818-1DOI Listing
June 2019

White blood cell mitochondrial DNA copy number is decreased in rheumatoid arthritis and linked with risk factors. A twin study.

J Autoimmun 2019 Jan 14;96:142-146. Epub 2018 Oct 14.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark; Unit of Human Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2018.09.008DOI Listing
January 2019

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

Authors:
Jeanne E Savage Philip R Jansen Sven Stringer Kyoko Watanabe Julien Bryois Christiaan A de Leeuw Mats Nagel Swapnil Awasthi Peter B Barr Jonathan R I Coleman Katrina L Grasby Anke R Hammerschlag Jakob A Kaminski Robert Karlsson Eva Krapohl Max Lam Marianne Nygaard Chandra A Reynolds Joey W Trampush Hannah Young Delilah Zabaneh Sara Hägg Narelle K Hansell Ida K Karlsson Sten Linnarsson Grant W Montgomery Ana B Muñoz-Manchado Erin B Quinlan Gunter Schumann Nathan G Skene Bradley T Webb Tonya White Dan E Arking Dimitrios Avramopoulos Robert M Bilder Panos Bitsios Katherine E Burdick Tyrone D Cannon Ornit Chiba-Falek Andrea Christoforou Elizabeth T Cirulli Eliza Congdon Aiden Corvin Gail Davies Ian J Deary Pamela DeRosse Dwight Dickinson Srdjan Djurovic Gary Donohoe Emily Drabant Conley Johan G Eriksson Thomas Espeseth Nelson A Freimer Stella Giakoumaki Ina Giegling Michael Gill David C Glahn Ahmad R Hariri Alex Hatzimanolis Matthew C Keller Emma Knowles Deborah Koltai Bettina Konte Jari Lahti Stephanie Le Hellard Todd Lencz David C Liewald Edythe London Astri J Lundervold Anil K Malhotra Ingrid Melle Derek Morris Anna C Need William Ollier Aarno Palotie Antony Payton Neil Pendleton Russell A Poldrack Katri Räikkönen Ivar Reinvang Panos Roussos Dan Rujescu Fred W Sabb Matthew A Scult Olav B Smeland Nikolaos Smyrnis John M Starr Vidar M Steen Nikos C Stefanis Richard E Straub Kjetil Sundet Henning Tiemeier Aristotle N Voineskos Daniel R Weinberger Elisabeth Widen Jin Yu Goncalo Abecasis Ole A Andreassen Gerome Breen Lene Christiansen Birgit Debrabant Danielle M Dick Andreas Heinz Jens Hjerling-Leffler M Arfan Ikram Kenneth S Kendler Nicholas G Martin Sarah E Medland Nancy L Pedersen Robert Plomin Tinca J C Polderman Stephan Ripke Sophie van der Sluis Patrick F Sullivan Scott I Vrieze Margaret J Wright Danielle Posthuma

Nat Genet 2018 07 25;50(7):912-919. Epub 2018 Jun 25.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41588-018-0152-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411041PMC
July 2018

Investigation of the 5q33.3 longevity locus and age-related phenotypes.

Aging (Albany NY) 2017 01;9(1):247-255

The Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, 5000 Odense C, Denmark.

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http://dx.doi.org/10.18632/aging.101156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310666PMC
January 2017

Somatically acquired structural genetic differences: a longitudinal study of elderly Danish twins.

Eur J Hum Genet 2016 10 20;24(10):1506-10. Epub 2016 Apr 20.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1038/ejhg.2016.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027681PMC
October 2016

Genetic Variants in KLOTHO Associate With Cognitive Function in the Oldest Old Group.

J Gerontol A Biol Sci Med Sci 2016 09 24;71(9):1151-9. Epub 2015 Sep 24.

The Danish Aging Research Center and The Danish Twin Registry, Epidemiology, Biostatistics and Biodemography Unit, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1093/gerona/glv163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978356PMC
September 2016

No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.

Exp Gerontol 2016 Jun 3;78:57-61. Epub 2016 Mar 3.

Epidemiology, Biostatistics and Biodemography, The Danish Aging Research Center, Department of Public Health, University of Southern Denmark, J.B. Winsloews Vej 9B, 5000 Odense C, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709PMC
June 2016

Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment.

Aging Cell 2016 Feb 8;15(1):49-55. Epub 2015 Oct 8.

The Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J.B. Winsloews Vej 9B, 5000, Odense C, Denmark.

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http://dx.doi.org/10.1111/acel.12407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717275PMC
February 2016

Association study of FOXO3A SNPs and aging phenotypes in Danish oldest-old individuals.

Aging Cell 2015 Feb 2;14(1):60-6. Epub 2014 Dec 2.

The Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Institute of Public Health, University of Southern Denmark, J.B. Winsloews Vej 9B, 5000, Odense C, Denmark; Department of Clinical Genetics, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark.

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http://dx.doi.org/10.1111/acel.12295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326903PMC
February 2015

Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals.

Exp Gerontol 2014 Sep 5;57:41-6. Epub 2014 May 5.

The Danish Aging Research Center, Institute of Public Health, University of Southern Denmark, J.B. Winsloews Vej 9B, 5000 Odense C, Denmark; Department of Clinical Genetics, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C, Denmark; Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2014.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149928PMC
September 2014

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Hum Mol Genet 2014 Aug 31;23(16):4420-32. Epub 2014 Mar 31.

Department of Molecular Epidemiology, Netherlands Consortium for Healthy Ageing,

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http://dx.doi.org/10.1093/hmg/ddu139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103672PMC
August 2014

Dog bite injuries to the hand.

J Plast Surg Hand Surg 2011 Apr;45(2):96-101

Department of Hand Surgery, Skåne University Hospital, Malmö, Sweden.

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http://dx.doi.org/10.3109/2000656X.2011.558735DOI Listing
April 2011

[From haematoma to sarcoma].

Ugeskr Laeger 2010 Jan;172(3):217-8

Glostrup Hospital, Ortopaedkirurgisk Afdeling, Denmark.

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January 2010

Can ultrastructural particle location predict aseptic loosening? A biopsy study of nonloose hip implants one year postoperative using three bearing material combinations.

J Long Term Eff Med Implants 2007 ;17(4):321-34

Department of Orthopaedic Surgery, Frederiksberg University Hospital, Denmark.

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April 2009

A snapshot of CNVs in the pig genome.

PLoS One 2008 16;3(12):e3916. Epub 2008 Dec 16.

Group of Molecular Genetics and Systems Biology, Department of Genetics and Biotechnology, Faculty of Agricultural Sciences, Aarhus University, Tjele, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0003916PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596487PMC
February 2009

Acute rotator cuff tear: do we miss the early diagnosis? A prospective study showing a high incidence of rotator cuff tears after shoulder trauma.

J Shoulder Elbow Surg 2007 Mar-Apr;16(2):174-80. Epub 2006 Dec 13.

Department of Orthopedic Surgery, University Hospital of Copenhagen, Gentofte, Denmark.

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http://dx.doi.org/10.1016/j.jse.2006.06.010DOI Listing
June 2007

No difference in early cellular response of the pseudo-synovial membrane after total hip arthroplasty: comparison of 3 combinations of bearing materials.

Acta Orthop 2006 Jun;77(3):402-12

Department of Orthopaedic Surgery, Frederiksberg University Hospital, Frederiksberg, Denmark.

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http://dx.doi.org/10.1080/17453670610046325DOI Listing
June 2006