Marianna Desideri

Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells.

Authors:

Marta Di Martile Chiara Gabellini Marianna Desideri Marta Matraxia Valentina Farini Elisabetta Valentini Simone Carradori Cristiana Ercolani Simonetta Buglioni Daniela Secci Massimiliano Andreazzoli Donatella Del Bufalo Daniela Trisciuoglio

J Exp Clin Cancer Res 2020 Jun 5;39(1):103. Epub 2020 Jun 5.

Preclinical Models and New Therapeutic Agents Unit, Department of Research and Advanced Technologies, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

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June 2020

Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages.

Authors:

Marta Di Martile Valentina Farini Francesca Maria Consonni Daniela Trisciuoglio Marianna Desideri Elisabetta Valentini Simona D'Aguanno Maria Grazia Tupone Simonetta Buglioni Cristiana Ercolani Enzo Gallo Bruno Amadio Irene Terrenato Maria Laura Foddai Antonio Sica Donatella Del Bufalo

J Immunother Cancer 2020 04;8(1)

Preclinical Models and New Therapeutic Agents Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy

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April 2020

microRNA-378a-5p iS a novel positive regulator of melanoma progression.

Authors:

Maria Grazia Tupone Simona D'Aguanno Marta Di Martile Elisabetta Valentini Marianna Desideri Daniela Trisciuoglio Sara Donzelli Andrea Sacconi Simonetta Buglioni Cristiana Ercolani Alessio Biagioni Gabriella Fibbi Luigi Fattore Rita Mancini Gennaro Ciliberto Giovanni Blandino Donatella Del Bufalo

Oncogenesis 2020 Feb 14;9(2):22. Epub 2020 Feb 14.

Preclinical Models and New Therapeutic Agents Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

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February 2020

Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb.

Authors:

Simona D'Aguanno Elisabetta Valentini Maria Grazia Tupone Marianna Desideri Marta Di Martile Manuela Spagnuolo Simonetta Buglioni Cristiana Ercolani Italia Falcone Marco De Dominici Michele Milella Maria Giulia Rizzo Bruno Calabretta Carlo Cota Andrea Anichini Daniela Trisciuoglio Donatella Del Bufalo

J Exp Clin Cancer Res 2018 Nov 19;37(1):278. Epub 2018 Nov 19.

Preclinical Models and New Therapeutic Agents Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

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November 2018

Histone deacetylase inhibitor ITF2357 leads to apoptosis and enhances doxorubicin cytotoxicity in preclinical models of human sarcoma.

Authors:

Marta Di Martile Marianna Desideri Maria Grazia Tupone Simonetta Buglioni Barbara Antoniani Carlotta Mastroiorio Rita Falcioni Virginia Ferraresi Nicola Baldini Roberto Biagini Michele Milella Daniela Trisciuoglio Donatella Del Bufalo

Oncogenesis 2018 Feb 23;7(2):20. Epub 2018 Feb 23.

Preclinical Models and New Therapeutic Agents Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

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February 2018

BCL-X overexpression promotes tumor progression-associated properties.

Authors:

Daniela Trisciuoglio Maria Grazia Tupone Marianna Desideri Marta Di Martile Chiara Gabellini Simonetta Buglioni Matteo Pallocca Gabriele Alessandrini Simona D'Aguanno Donatella Del Bufalo

Cell Death Dis 2017 12 13;8(12):3216. Epub 2017 Dec 13.

Preclinical Models and New Therapeutic Agents Unit, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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December 2017

Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma.

Authors:

Giulia Fianco Maria Patrizia Mongiardi Andrea Levi Teresa De Luca Marianna Desideri Daniela Trisciuoglio Donatella Del Bufalo Irene Cinà Anna Di Benedetto Marcella Mottolese Antonietta Gentile Diego Centonze Fabrizio Ferrè Daniela Barilà

Elife 2017 06 8;6. Epub 2017 Jun 8.

Department of Biology, University of Rome Tor Vergata, Rome, Italy.

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June 2017

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells.

Authors:

Marta Di Martile Marianna Desideri Teresa De Luca Chiara Gabellini Simonetta Buglioni Adriana Eramo Giovanni Sette Michele Milella Dante Rotili Antonello Mai Simone Carradori Daniela Secci Ruggero De Maria Donatella Del Bufalo Daniela Trisciuoglio

Oncotarget 2016 Mar;7(10):11332-48

Department of Research, Advanced Diagnostics and Technological Innovation, Regina Elena National Cancer Institute, Rome, Italy.

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March 2016

NAADP-Dependent Ca(2+) Signaling Controls Melanoma Progression, Metastatic Dissemination and Neoangiogenesis.

Authors:

Annarita Favia Irene Pafumi Marianna Desideri Fabrizio Padula Camilla Montesano Daniela Passeri Carmine Nicoletti Augusto Orlandi Donatella Del Bufalo Manuel Sergi Elio Ziparo Fioretta Palombi Antonio Filippini

Sci Rep 2016 Jan 6;6:18925. Epub 2016 Jan 6.

Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Unit of Histology and Medical Embryology,SAPIENZA University of Rome, 16 Via A. Scarpa, 00161 Rome, Italy.

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January 2016

miR-211 and MITF modulation by Bcl-2 protein in melanoma cells.

Authors:

Teresa De Luca Andrea Pelosi Daniela Trisciuoglio Simona D'Aguanno Marianna Desideri Valentina Farini Marta Di Martile Barbara Bellei Maria Grazia Tupone Antonio Candiloro Giulia Regazzo Maria Giulia Rizzo Donatella Del Bufalo

Mol Carcinog 2016 12 24;55(12):2304-2312. Epub 2015 Nov 24.

Experimental Chemotherapy Laboratory, Regina Elena National Cancer Institute, Rome, Italy.

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December 2016

TLR3 engagement induces IRF-3-dependent apoptosis in androgen-sensitive prostate cancer cells and inhibits tumour growth in vivo.

Authors:

Guido Gambara Marianna Desideri Antonella Stoppacciaro Fabrizio Padula Paola De Cesaris Donatella Starace Andrea Tubaro Donatella Del Bufalo Antonio Filippini Elio Ziparo Anna Riccioli

J Cell Mol Med 2015 Feb 2;19(2):327-39. Epub 2014 Dec 2.

Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Section of Histology and Medical Embryology, Sapienza University of Rome, Rome, Italy.

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February 2015

VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling.

Authors:

Annarita Favia Marianna Desideri Guido Gambara Alessio D'Alessio Margarida Ruas Bianca Esposito Donatella Del Bufalo John Parrington Elio Ziparo Fioretta Palombi Antony Galione Antonio Filippini

Proc Natl Acad Sci U S A 2014 Nov 20;111(44):E4706-15. Epub 2014 Oct 20.

Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Unit of Histology and Medical Embryology, Sapienza University of Rome, 00161 Rome, Italy;

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November 2014

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer.

Authors:

Donatella Del Bufalo Marianna Desideri Teresa De Luca Marta Di Martile Chiara Gabellini Valentina Monica Simone Busso Adriana Eramo Ruggero De Maria Michele Milella Daniela Trisciuoglio

Mol Cancer 2014 Oct 9;13:230. Epub 2014 Oct 9.

Experimental Chemotherapy Laboratory, Regina Elena National Cancer Institute, Rome, Italy.

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October 2014

BH4 domain of bcl-2 protein is required for its proangiogenic function under hypoxic condition.

Authors:

Chiara Gabellini Teresa De Luca Daniela Trisciuoglio Marianna Desideri Marta Di Martile Daniela Passeri Antonio Candiloro Mauro Biffoni Maria Giulia Rizzo Augusto Orlandi Donatella Del Bufalo

Carcinogenesis 2013 Nov 8;34(11):2558-67. Epub 2013 Jul 8.

Experimental Chemotherapy Laboratory, Regina Elena National Cancer Institute, Rome 00158, Italy.

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November 2013

Papillary carcinoma of the thyroid: high expression of COX-2 and low expression of KAI-1/CD82 are associated with increased tumor invasiveness.

Authors:

Stefania Scarpino Enrico Duranti Simona Giglio Arianna Di Napoli Dino Galafate Donatella Del Bufalo Marianna Desideri Fabio Socciarelli Antonella Stoppacciaro Luigi Ruco

Thyroid 2013 Sep 27;23(9):1127-37. Epub 2013 Aug 27.

1 Department of Clinical and Molecular Medicine, "Sapienza" University, Sant'Andrea Hospital, Rome, Italy .

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September 2013

Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth.

Authors:

Daniela Trisciuoglio Teresa De Luca Marianna Desideri Daniela Passeri Chiara Gabellini Stefania Scarpino Chengyu Liang Augusto Orlandi Donatella Del Bufalo

Neoplasia 2013 Mar;15(3):315-27

Experimental Chemotherapy Laboratory, Regina Elena National Cancer Institute, Rome, Italy.

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March 2013

LMNA knock-down affects differentiation and progression of human neuroblastoma cells.

Authors:

Giovanna Maresca Manuela Natoli Marta Nardella Ivan Arisi Daniela Trisciuoglio Marianna Desideri Rossella Brandi Simona D'Aguanno Maria Rita Nicotra Mara D'Onofrio Andrea Urbani Pier Giorgio Natali Donatella Del Bufalo Armando Felsani Igea D'Agnano

PLoS One 2012 26;7(9):e45513. Epub 2012 Sep 26.

CNR-Institute of Cell Biology and Neurobiology, Santa Lucia Foundation-IRCCS, Rome, Italy.

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April 2013

Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125.

Authors:

Simona Caporali Ester Alvino Lauretta Levati Alessia I Esposito Marina Ciomei Maria G Brasca Donatella Del Bufalo Marianna Desideri Enzo Bonmassar Ulrich Pfeffer Stefania D'Atri

Biochem Pharmacol 2012 Sep 13;84(5):598-611. Epub 2012 Jun 13.

Laboratory of Molecular Oncology, Istituto Dermopatico dell'Immacolata-IRCCS, Via dei Monti di Creta 104, 00167 Rome, Italy.

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September 2012

The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms.

J Mol Med (Berl) 2012 Jun 4;90(6):667-79. Epub 2012 Jan 4.

Division of Medical Oncology A, Laboratory of Experimental Preclinical Chemotherapy and Translational Oncogenomics, Regina Elena National Cancer Institute, Chianesi, n. 53, 00144, Rome, Italy.

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June 2012