Mariana J Kaplan

Mariana J Kaplan

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Mariana J Kaplan

Mariana J Kaplan

Publications by authors named "Mariana J Kaplan"

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Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus.

Proc Natl Acad Sci U S A 2020 Mar 24;117(10):5409-5419. Epub 2020 Feb 24.

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1916897117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071891PMC
March 2020

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.

Immunity 2020 Mar;52(3):513-527.e8

Complement and Inflammation Research Section (CIRS), National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD 20892, USA; School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London SE1 9RT, UK; Institute for Systemic Inflammation Research, University of Lübeck, Lübeck 23562, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.02.006DOI Listing
March 2020

NETs spread ever wider in rheumatic diseases.

Nat Rev Rheumatol 2020 Feb;16(2):73-74

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41584-019-0352-1DOI Listing
February 2020

Of larks and owls.

Authors:
Mariana J Kaplan

Nat Immunol 2020 Feb;21(2):104-105

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41590-019-0579-7DOI Listing
February 2020

Use of Magnetic Resonance Imaging to Identify Immune Checkpoint Inhibitor-Induced Inflammatory Arthritis.

JAMA Netw Open 2020 Feb 5;3(2):e200032. Epub 2020 Feb 5.

Office of the Clinical Director, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jamanetworkopen.2020.0032DOI Listing
February 2020

Deadliest catch: neutrophil extracellular traps in autoimmunity.

Curr Opin Rheumatol 2020 Jan;32(1):64-70

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http://dx.doi.org/10.1097/BOR.0000000000000667DOI Listing
January 2020

The mechanics of myeloid cells.

Biol Cell 2020 Jan 9. Epub 2020 Jan 9.

National Heart and Lung Institute, Imperial College London.

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http://dx.doi.org/10.1111/boc.201900084DOI Listing
January 2020

Equity and diversity in academic medicine: a perspective from the JCI editors.

J Clin Invest 2019 Oct;129(10):3974-3977

Department of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1172/JCI130902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763240PMC
October 2019

Myeloid-Specific Deletion of Peptidylarginine Deiminase 4 Mitigates Atherosclerosis.

Front Immunol 2018 26;9:1680. Epub 2018 Jul 26.

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fimmu.2018.01680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094966PMC
September 2019

NETched in Stone.

Immunity 2019 09;51(3):413-414

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Disease, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.08.015DOI Listing
September 2019

The Role of Neutrophils and Neutrophil Extracellular Traps in Vascular Damage in Systemic Lupus Erythematosus.

J Clin Med 2019 Aug 28;8(9). Epub 2019 Aug 28.

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.3390/jcm8091325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780421PMC
August 2019

Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2.

Blood 2019 07 23;134(4):395-406. Epub 2019 Apr 23.

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1182/blood.2018892752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659253PMC
July 2019

Response to: 'Neutrophil extracellular traps and low-density granulocytes are associated with the interferon signature in systemic lupus erythematosus, but not in antiphospholipid syndrome' by van den Hoogen .

Ann Rheum Dis 2019 Jul 4. Epub 2019 Jul 4.

Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA

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http://dx.doi.org/10.1136/annrheumdis-2019-215811DOI Listing
July 2019

Real-time deformability cytometry reveals sequential contraction and expansion during neutrophil priming.

J Leukoc Biol 2019 Jun 5;105(6):1143-1153. Epub 2019 Mar 5.

Department of Pediatrics, University Clinic Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

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http://doi.wiley.com/10.1002/JLB.MA0718-295RR
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http://dx.doi.org/10.1002/JLB.MA0718-295RRDOI Listing
June 2019

PAM3 supports the generation of M2-like macrophages from lupus patient monocytes and improves disease outcome in murine lupus.

J Autoimmun 2019 May 22;99:24-32. Epub 2019 Jan 22.

Cancer and Inflammation Program, National Cancer Institute, NIH, Frederick, MD 21720, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2019.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462249PMC
May 2019

Neutrophils in Rheumatoid Arthritis: Breaking Immune Tolerance and Fueling Disease.

Trends Mol Med 2019 03 29;25(3):215-227. Epub 2019 Jan 29.

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714914183024
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http://dx.doi.org/10.1016/j.molmed.2018.12.008DOI Listing
March 2019

Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils.

Clin Immunol 2018 11 22;196:110-116. Epub 2018 Nov 22.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413498PMC
November 2018

Hepatocytes and neutrophils cooperatively suppress bacterial infection by differentially regulating lipocalin-2 and neutrophil extracellular traps.

Hepatology 2018 10 10;68(4):1604-1620. Epub 2018 May 10.

Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1002/hep.29919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173649PMC
October 2018

Cardiovascular disease in systemic lupus erythematosus: an update.

Curr Opin Rheumatol 2018 09;30(5):441-448

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000528DOI Listing
September 2018

Differential ubiquitination in NETs regulates macrophage responses in systemic lupus erythematosus.

Ann Rheum Dis 2018 06 27;77(6):944-950. Epub 2018 Mar 27.

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1136/annrheumdis-2017-212617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560641PMC
June 2018

Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance.

Lupus Sci Med 2018 14;5(1):e000259. Epub 2018 May 14.

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1136/lupus-2018-000259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950641PMC
May 2018

Brief Report: Drugs Implicated in Systemic Autoimmunity Modulate Neutrophil Extracellular Trap Formation.

Arthritis Rheumatol 2018 03 23;70(3):468-474. Epub 2018 Jan 23.

National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland.

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http://doi.wiley.com/10.1002/art.40372
Publisher Site
http://dx.doi.org/10.1002/art.40372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826843PMC
March 2018

Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".

Sci Immunol 2018 03;3(21)

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1126/sciimmunol.aar3701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497166PMC
March 2018

A High-Throughput Real-Time Imaging Technique To Quantify NETosis and Distinguish Mechanisms of Cell Death in Human Neutrophils.

J Immunol 2018 01 1;200(2):869-879. Epub 2017 Dec 1.

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892; and

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http://dx.doi.org/10.4049/jimmunol.1700905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760330PMC
January 2018

Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis.

Clin Immunol 2017 12 9;185:59-73. Epub 2016 Aug 9.

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299061PMC
December 2017

Editorial: NETosis 2: The Excitement Continues.

Front Immunol 2017 20;8:1318. Epub 2017 Oct 20.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.3389/fimmu.2017.01318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655467PMC
October 2017

Metabolic abnormalities and oxidative stress in lupus.

Curr Opin Rheumatol 2017 Sep;29(5):442-449

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586499PMC
September 2017

Unraveling Vascular Inflammation: From Immunology to Imaging.

J Am Coll Cardiol 2017 Sep;70(11):1403-1412

Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.07.750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658004PMC
September 2017

Disentangling the role of neutrophil extracellular traps in rheumatic diseases.

Curr Opin Rheumatol 2017 01;29(1):65-70

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050586PMC
January 2017

Dysfunction of endothelial progenitor cells is associated with the type I IFN pathway in patients with polymyositis and dermatomyositis.

Rheumatology (Oxford) 2016 11 7;55(11):1987-1992. Epub 2016 Aug 7.

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/rheumatology/kew288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088625PMC
November 2016

Induction and Quantification of NETosis.

Curr Protoc Immunol 2016 11 1;115:14.41.1-14.41.14. Epub 2016 Nov 1.

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1002/cpim.16DOI Listing
November 2016

Review: Neutrophils as Invigorated Targets in Rheumatic Diseases.

Arthritis Rheumatol 2016 09 29;68(9):2071-82. Epub 2016 Jul 29.

National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1002/art.39745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001882PMC
September 2016

Update on cardiovascular disease in lupus.

Curr Opin Rheumatol 2016 09;28(5):468-76

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965310PMC
September 2016

Alterations in nuclear structure promote lupus autoimmunity in a mouse model.

Dis Model Mech 2016 08 9;9(8):885-97. Epub 2016 Jun 9.

Section of Rheumatology, Temple University School of Medicine, Philadelphia, PA 19140, USA

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http://dx.doi.org/10.1242/dmm.024851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007980PMC
August 2016

The role of neutrophils and NETosis in autoimmune and renal diseases.

Nat Rev Nephrol 2016 07 31;12(7):402-13. Epub 2016 May 31.

National Institute of Arthritis and Musculoskeletal and Skin Diseases, Systemic Autoimmunity Branch, Intramural Research Program, National Institutes of Health, Room 6D 47C, 10 Center Drive, Bethesda, MD 20892-1930, USA.

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http://dx.doi.org/10.1038/nrneph.2016.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510606PMC
July 2016

Placental histology and neutrophil extracellular traps in lupus and pre-eclampsia pregnancies.

Lupus Sci Med 2016 27;3(1):e000134. Epub 2016 Apr 27.

Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA; Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1136/lupus-2015-000134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854113PMC
May 2016

At the Bench: Neutrophil extracellular traps (NETs) highlight novel aspects of innate immune system involvement in autoimmune diseases.

J Leukoc Biol 2016 Feb 2;99(2):253-64. Epub 2015 Oct 2.

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1189/jlb.5BT0615-247RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718195PMC
February 2016

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.

Nat Med 2016 Feb 18;22(2):146-53. Epub 2016 Jan 18.

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIH), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/nm.4027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742415PMC
February 2016

Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice.

Ann Rheum Dis 2015 Dec 7;74(12):2199-206. Epub 2014 Aug 7.

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1136/annrheumdis-2014-205365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320672PMC
December 2015

Severity of Psoriasis Associates With Aortic Vascular Inflammation Detected by FDG PET/CT and Neutrophil Activation in a Prospective Observational Study.

Arterioscler Thromb Vasc Biol 2015 Dec 8;35(12):2667-76. Epub 2015 Oct 8.

From the Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute (H.B.N., B.N., E.S., H.T., T.S., Q.N., A.A.J., J.D., S.M.R., J.D., M.P.P., N.N.M.), Dermatology Branch, Center for Cancer Research, National Cancer Institute (H.B.N.), Molecular Biomedical Imaging Laboratory (M.A.A.), and Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (M.J.K.), National Institutes of Health, Bethesda, MD; Englewood Hospital, NJ (P.K.); The Washington Dermatology Center, Rockville, MD (R.B.P.); Department of Dermatology, George Washington Hospital, Washington DC (R.B.P., A.E.); DermAssociates, Silver Spring, MD (B.N.L.); and Department of Dermatology, Department of Biostatistics and Epidemiology, and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia (J.M.G.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662627PMC
December 2015

The development of depressive symptoms during medical internship stress predicts worsening vascular function.

J Psychosom Res 2015 Sep 18;79(3):243-5. Epub 2015 Jun 18.

Department of Psychiatry, University of Michigan, Ann Arbor, MI, United States; Molecular and Behavioral Neuroscience Institute, Department of Psychiatry, University of Michigan, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychores.2015.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522220PMC
September 2015

The role of neutrophils in the pathogenesis of systemic lupus erythematosus.

Curr Opin Rheumatol 2015 Sep;27(5):448-53

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000197DOI Listing
September 2015

The development of depressive symptoms during medical internship stress predicts worsening vascular function.

J Psychosom Res 2015 Sep 18;79(3):243-5. Epub 2015 Jun 18.

Department of Psychiatry, University of Michigan, Ann Arbor, MI, United States; Molecular and Behavioral Neuroscience Institute, Department of Psychiatry, University of Michigan, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychores.2015.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522220PMC
September 2015

Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2.

Ann Rheum Dis 2015 Jul 25;74(7):1417-24. Epub 2014 Feb 25.

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1136/annrheumdis-2013-204837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143484PMC
July 2015

Interleukin 10 hampers endothelial cell differentiation and enhances the effects of interferon α on lupus endothelial cell progenitors.

Rheumatology (Oxford) 2015 Jun 20;54(6):1114-23. Epub 2014 Nov 20.

Department of Internal Medicine, Division of Rheumatology, Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI and Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Disorders, National Institutes of Health, Bethesda, MD, USA

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http://dx.doi.org/10.1093/rheumatology/keu431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447841PMC
June 2015

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils.

J Autoimmun 2015 Apr 28;58:59-66. Epub 2015 Jan 28.

Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2015.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363276PMC
April 2015

Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors.

J Med Chem 2015 Feb 16;58(3):1337-44. Epub 2015 Jan 16.

Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School , 364 Plantation Street, Worcester, Massachusetts, 01605, United States.

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http://dx.doi.org/10.1021/jm501636xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610306PMC
February 2015

Detection of SLE antigens in neutrophil extracellular traps (NETs).

Methods Mol Biol 2014 ;1134:151-61

Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/978-1-4939-0326-9_11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123114PMC
September 2014

The inflammasome and lupus: another innate immune mechanism contributing to disease pathogenesis?

Curr Opin Rheumatol 2014 Sep;26(5):475-81

aDivision of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan bSystemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Disorders, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153426PMC
September 2014

Reply: To PMID 24449582.

Arthritis Rheumatol 2014 Aug;66(8):2311-2

University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1002/art.38677DOI Listing
August 2014

Prevalence of subclinical atherosclerosis is increased in systemic sclerosis and is associated with serum proteins: a cross-sectional, controlled study of carotid ultrasound.

Rheumatology (Oxford) 2014 Apr 19;53(4):704-13. Epub 2013 Dec 19.

Division of Rheumatology/Department of Internal Medicine, University of Michigan Scleroderma Program, Suite 7C27, 300 North Ingalls Street, SPC 5422, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1093/rheumatology/ket411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042927PMC
April 2014

Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis.

Circ Res 2014 Mar 14;114(6):947-56. Epub 2014 Jan 14.

From the Department of Rheumatology (J.S.K., A.A.O., S.Y., R.C.G.) and Cardiology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI (W.L., C.G., D.T.E.); Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD (W.Z., M.J.K.); and Department of Chemistry, The Scripps Research Institute, Jupiter, FL (V.S., P.R.T.).

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http://dx.doi.org/10.1161/CIRCRESAHA.114.303312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185401PMC
March 2014

Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease.

J Immunol 2013 Nov;191(10):4895-901

Division of Rheumatology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109.

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http://dx.doi.org/10.4049/jimmunol.1302005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836506PMC
November 2013

The peroxisome-proliferator activated receptor-γ agonist pioglitazone modulates aberrant T cell responses in systemic lupus erythematosus.

Clin Immunol 2013 Oct 20;149(1):119-32. Epub 2013 Jul 20.

Division of Rheumatology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.clim.2013.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184099PMC
October 2013