Publications by authors named "Mariana C Castells"

75 Publications

Successful administration of omalizumab by desensitization protocol following systemic reactions in 12 patients.

J Allergy Clin Immunol Pract 2021 Feb 15. Epub 2021 Feb 15.

Division of Allergy and Clinical Immunology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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February 2021

Maintaining Safety with SARS-CoV-2 Vaccines. Reply.

N Engl J Med 2021 Feb 10. Epub 2021 Feb 10.

Vanderbilt University Medical Center, Nashville, TN.

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February 2021

Distinct Small Intestine Mast Cell Histologic Changes in Patients With Hereditary Alpha-tryptasemia and Mast Cell Activation Syndrome.

Am J Surg Pathol 2021 Jan 20. Epub 2021 Jan 20.

Division of Gastroenterology, Hepatology, and Endoscopy Division of Allergy and Clinical Immunology, Mastocytosis Center Departments of Pathology Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA Department of Pediatrics, Division of Pediatric Gastroenterology Department of Medicine, Division of Gastroenterology, University of Florida, Gainesville, FL Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD Department of Medicine, Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, MI.

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January 2021

Maintaining Safety with SARS-CoV-2 Vaccines.

N Engl J Med 2021 02 30;384(7):643-649. Epub 2020 Dec 30.

From Brigham and Women's Hospital, Boston (M.C.C.); and the Department of Medicine, Vanderbilt University Medical Center, Nashville (E.J.P.).

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February 2021

Drug allergy labeling and delabeling in the coronavirus disease 2019 era: What is important and what do we need to know.

Ann Allergy Asthma Immunol 2020 06;124(6):523-525

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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June 2020

Anaphylaxis: Parts Unknown.

J Allergy Clin Immunol Pract 2020 04;8(4):1216-1218

Division of Allergic Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minn.

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April 2020

Anaphylaxis: watch out, it is everywhere now!

Ann Allergy Asthma Immunol 2020 02;124(2):116-117

Hypersensitivity and Desensitization Center, Mastocytosis Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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February 2020

Soluble FcεRI, IgE, and tryptase as potential biomarkers of rapid desensitizations for platin IgE sensitized cancer patients.

J Allergy Clin Immunol Pract 2020 06 4;8(6):2085-2088.e10. Epub 2020 Feb 4.

Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.

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June 2020

Idiopathic anaphylaxis yardstick: Practical recommendations for clinical practice.

Ann Allergy Asthma Immunol 2020 01 9;124(1):16-27. Epub 2019 Sep 9.

Departments of Medicine and Pediatrics, Divisions of Allergy and Immunology, University of Tennessee, Memphis, Tennessee. Electronic address:

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January 2020

Blisters, Vaccines, and Mast Cells: A Difficult Case of Diffuse Cutaneous Mastocytosis.

J Allergy Clin Immunol Pract 2019 04;7(4):1370-1372

Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham, and Women's Hospital, Harvard Medical School, Boston, Mass.

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April 2019

Rituximab hypersensitivity and desensitization: a personalized approach to treat cancer and connective tissue diseases.

Ann Allergy Asthma Immunol 2019 07 16;123(1):11-15. Epub 2019 Mar 16.

Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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July 2019

Challenges and safety of beta-lactam desensitization during extracorporeal membrane oxygenation.

Ann Allergy Asthma Immunol 2019 06 13;122(6):661-663. Epub 2019 Mar 13.

Brigham and Women's Hospital, Boston, Massachusetts; Drug Hypersensitivity and Desensitization Center at Brigham and Women's Hospital, Boston, Massachusetts.

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June 2019

Capturing Drug-Induced Anaphylaxis Through Electronic Health Records: A Step Forward.

J Allergy Clin Immunol Pract 2019 01;7(1):112-113

Harvard Medical School, Brigham and Women's University, Boston, Mass. Electronic address:

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January 2019

The Contribution of the Basophil Activation Test to the Diagnosis of Hypersensitivity Reactions to Oxaliplatin.

Int Arch Allergy Immunol 2018;177(3):274-280. Epub 2018 Jul 24.

Unidade de Imunologia Clínica, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.

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December 2018

Mastocytosis: Moving the Field to Precision and Personalized Medicine.

Immunol Allergy Clin North Am 2018 08 9;38(3):xv-xvii. Epub 2018 Jun 9.

Drug Hypersensitivity and Desensitization Center, Mastoctytosis Center, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Room 5002, Boston, MA 02115, USA; 850 Boylston Street, Brookline, MA 02445, USA. Electronic address:

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August 2018

Patient Perceptions in Mast Cell Disorders.

Immunol Allergy Clin North Am 2018 08;38(3):505-525

Department of Medicine, Division of Rheumatology, Immunology, and Allergy, Mastocytosis Center, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA 02115, USA.

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August 2018

Specific questionnaire detects a high incidence of intra-operative hypersensitivity reactions.

Clinics (Sao Paulo) 2018 05 17;73:e287. Epub 2018 May 17.

Divisao de Imunologia Clinica e Alergia, Faculdade de Medicina (FMUSP), Universidade de Sao Paulo, Sao Paulo, SP, BR.

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May 2018

Drug Hypersensitivity and Desensitizations.

Immunol Allergy Clin North Am 2017 11;37(4):xvii-xviii

Drug Hypersensitivity and Desensitization Center, Mastocytosis Center Brigham and Women's Hospital/Dana Farber Cancer Institute, Harvard Medical School, 60 Fenwood Road, Room 5002, Boston, MA 02115, USA; 850 Boylston Street, Brookline, MA 02445, USA. Electronic address:

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November 2017

Invited Commentary: Mast Cell Activation.

Curr Allergy Asthma Rep 2017 09 27;17(10):73. Epub 2017 Sep 27.

Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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September 2017

Fatal anaphylaxis caused by gadolinium due to beta-tryptase-induced hemorragic diathesis.

J Allergy Clin Immunol Pract 2017 Sep - Oct;5(5):1433-1434. Epub 2017 Jun 19.

Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.

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June 2019

Drug Hypersensitivity and Desensitizations: Mechanisms and New Approaches.

Int J Mol Sci 2017 Jun 20;18(6). Epub 2017 Jun 20.

Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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June 2017

Drug Allergy: Phenotypes, Endotypes, and Biomarkers.

J Allergy Clin Immunol Pract 2017 May - Jun;5(3):626-627

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address:

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March 2019

Penicillin Allergy Testing: A Key Component of Antibiotic Stewardship.

Clin Infect Dis 2017 02;64(4):531-532

Department of Allergy and Clinical Immunology, Cleveland Clinic, Ohio.

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February 2017

Basophil Activation Test is a Relevant Biomarker of the Outcome of Rapid Desensitization in Platinum Compounds-Allergy.

J Allergy Clin Immunol Pract 2017 May - Jun;5(3):728-736. Epub 2016 Dec 27.

Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.

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February 2018

Carboplatin-allergic patients undergoing desensitization: prevalence and impact of the BRCA 1/2 mutation.

J Allergy Clin Immunol Pract 2017 May - Jun;5(3):816-818. Epub 2016 Oct 17.

Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Mass. Electronic address:

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February 2019

Reply.

J Allergy Clin Immunol Pract 2016 Jan-Feb;4(1):190-1

Brigham and Women's Hospital, Boston, Mass.

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May 2016

Risk stratification and skin testing to guide re-exposure in taxane-induced hypersensitivity reactions.

J Allergy Clin Immunol 2016 Apr 23;137(4):1154-1164.e12. Epub 2015 Dec 23.

Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Mass. Electronic address:

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April 2016