Publications by authors named "Mariah Brown"

38 Publications

Tissue Expansion Before Mohs Micrographic Surgery for a Large Scalp Tumor.

Dermatol Surg 2021 Jul;47(7):997-998

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000003075DOI Listing
July 2021

Aggressive Cutaneous Squamous Cell Carcinoma as an Adult Manifestation of Incontinentia Pigmenti.

Dermatol Surg 2021 Jun;47(6):824-826

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000002780DOI Listing
June 2021

BRAF/MEK inhibitor-induced remission of primary cutaneous myoepithelial carcinoma after local recurrence.

JAAD Case Rep 2020 Aug 23;6(8):783-786. Epub 2020 Jul 23.

Departments of Dermatology, University of Colorado, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.jdcr.2019.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525063PMC
August 2020

Treatment of steroid atrophy with hyaluronic acid filler.

JAAD Case Rep 2020 Oct 28;6(10):973-974. Epub 2020 Jul 28.

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.jdcr.2020.07.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508711PMC
October 2020

Early neurodevelopmental and medical profile in children with sex chromosome trisomies: Background for the prospective eXtraordinarY babies study to identify early risk factors and targets for intervention.

Am J Med Genet C Semin Med Genet 2020 06 7;184(2):428-443. Epub 2020 Jun 7.

Pediatric Endocrinology, University of Colorado School of Medicine Department of Pediatrics, Aurora, Colorado, USA.

Sex chromosome trisomies (SCT), including Klinefelter syndrome/XXY, Trisomy X, and XYY syndrome, occur in 1 of every 500 births. The past decades of research have resulted in a broadening of known associated medical comorbidities as well as advances in psychological research. This review summarizes what is known about early neurodevelopmental, behavioral, and medical manifestations in young children with SCT. We focus on recent research and unanswered questions related to the risk for neurodevelopmental disorders that commonly present in the first years of life and discuss the medical and endocrine manifestations of SCT at this young age. The increasing rate of prenatal SCT diagnoses provides the opportunity to address gaps in the existing literature in a new birth cohort, leading to development of the eXtraordinarY Babies Study. This study aims to better describe and compare the natural history of SCT conditions, identify predictors of positive and negative outcomes in SCT, evaluate developmental and autism screening measures commonly used in primary care practices for the SCT population, and build a rich data set linked to a bank of biological samples for future study. Results from this study and ongoing international research efforts will inform evidence-based care and improve health and neurodevelopmental outcomes.
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http://dx.doi.org/10.1002/ajmg.c.31807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413625PMC
June 2020

A Large Surgical Defect of the Central Upper Lip.

Dermatol Surg 2020 May 29. Epub 2020 May 29.

Both authors are affiliated with the Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000002365DOI Listing
May 2020

Analysis of Speaking Opportunities by Gender at National Dermatologic Surgery Conferences.

Dermatol Surg 2020 09;46(9):1195-1201

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

Background: Although gender disparities for those entering medicine have equalized, the number of women advancing in academia has remained low. Studies have demonstrated that women's representation at academic medical conferences has also remained low across multiple fields. Given that conference presentations and national reputation serve as metrics for academic promotion, women's representation at dermatology conferences may provide insight into women's academic productivity.

Objective: To examine the gender composition of presenters and speaking time at the 2 main national dermatologic surgery conferences.

Methods: Speaker's gender, presentation time, and topics were collected for 2009 to 2017 for the American College of Mohs Surgery (ACMS) and the American Society for Dermatologic Surgery (ASDS) Annual Meetings.

Results: Women had significantly fewer speaking opportunities and speaking minutes at both conferences. This disparity was most pronounced in reconstruction topics and least pronounced in cosmetics topics. The majority of top speakers, repeat speakers, and keynote speakers were men for both conferences. Oral abstracts showed no gender disparity at either conference.

Conclusion: Women spoke less than men at both the ASDS and ACMS annual meetings over multiple years studied. Recently, this disparity in speaking opportunities has decreased. Further studies are needed to evaluate the speaking opportunities for women at other types of dermatology conferences.
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http://dx.doi.org/10.1097/DSS.0000000000002275DOI Listing
September 2020

Use of Oxymetazoline Hydrochloride 0.05% Soaked Pledgets for Hemostasis of Exposed Nasal Mucosa After Dermatologic Surgery.

Dermatol Surg 2021 02;47(2):305-306

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000002272DOI Listing
February 2021

Second Intention Healing of a Large Surgical Defect of the Scalp.

Dermatol Surg 2021 02;47(2):275-277

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000002267DOI Listing
February 2021

Initial skin cancer screening for solid organ transplant recipients in the United States: Delphi method development of expert consensus guidelines.

Transpl Int 2019 Dec 8;32(12):1268-1276. Epub 2019 Oct 8.

Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Skin cancer is the most common malignancy affecting solid organ transplant recipients (SOTR), and SOTR experience increased skin cancer-associated morbidity and mortality. There are no formal multidisciplinary guidelines for skin cancer screening after transplant, and current practices are widely variable. We conducted three rounds of Delphi method surveys with a panel of 84 U.S. dermatologists and transplant physicians to establish skin cancer screening recommendations for SOTR. The transplant team should risk stratify SOTR for screening, and dermatologists should perform skin cancer screening by full-body skin examination. SOTR with a history of skin cancer should continue regular follow-up with dermatology for skin cancer surveillance. High-risk transplant patients include thoracic organ recipients, SOTR age 50 and above, and male SOTR. High-risk Caucasian patients should be screened within 2 years after transplant, all Caucasian, Asian, Hispanic, and high-risk African American patients should be screened within 5 years after transplant. No consensus was reached regarding screening for low-risk African American SOTR. We propose a standardized approach to skin cancer screening in SOTR based on multidisciplinary expert consensus. These guidelines prioritize and emphasize the need for screening for SOTR at greatest risk for skin cancer.
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http://dx.doi.org/10.1111/tri.13520DOI Listing
December 2019

Micrographic Surgery and Dermatologic Oncology Fellowship Selection Criteria.

Authors:
Mariah Brown

Dermatol Surg 2019 10;45(10):1320-1321

Department of Dermatology University of Colorado School of Medicine Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000001963DOI Listing
October 2019

Surgical Dressings and Novel Skin Substitutes.

Dermatol Clin 2019 Jul;37(3):349-366

Mohs Micrographic Surgery and Cutaneous Oncology, Department of Dermatology, University of Colorado Hospital and School of Medicine, University of Colorado, 1665 Aurora Court, Mail Stop F703, Aurora, CO 80045, USA. Electronic address:

Dressings are integrally tied to wound outcomes in dermatologic surgery. Due to the wide range of wound types and dressing options available, dressing selection can be a formidable task. An understanding of dressing materials and their unique properties allows for a tailored approach to postoperative wound care. Conventional layered dressings often are suitable for uncomplicated dermatologic surgery wounds. Occlusive dressings and tissue-engineered skin substitutes may be warranted in more complex cases. This review is intended to equip the reader with the knowledge and confidence to successfully manage surgical wounds in dermatology.
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http://dx.doi.org/10.1016/j.det.2019.03.005DOI Listing
July 2019

PD-1 inhibitor induced alopecia areata.

Dermatol Online J 2018 Dec 15;24(12). Epub 2018 Dec 15.

Division of Cutaneous Oncology, Department of Internal Medicine, University of Colorado School of Medicine, Aurora, Colorado.

Immune checkpoint modulators are becoming more prevalent in clinical use for the treatment of metastatic melanoma and other malignancies. These drugs, including programmed death 1 (PD-1) inhibitors, have a high incidence of immune adverse events, including cutaneous manifestations. Alopecia is a known side effect with these drugs, but previous reports describe chemotherapy-induced alopecia. We report a case of alopecia areata in a patient on monotherapy with pembrolizumab (PD-1 inhibitor). It is important for the dermatologist to recognize and appropriately treat to decrease morbidity for these patients.
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December 2018

Activities to Invigorate a Student Chapter of the IEEE Engineering in Medicine and Biology Society.

Annu Int Conf IEEE Eng Med Biol Soc 2018 Jul;2018:1648-1651

An IEEE Engineering in Medicine and Biology Society (EMBS) student chapter can play an important service role for collegiate biomedical curricula, supporting (a) faculty and administrators as they offer biomedical programs and work to strengthen industry/community relationships, and (b) students as they engage in engineering skill development and seek industry employment, graduate school opportunities, or medical school placement. This paper summarizes recent projects and activities sponsored by the Kansas State University (KSU) Student Chapter of the IEEE EMBS - efforts intended to maintain interest in the student chapter while supporting its service role. Such a role will become more important in upcoming years in light of the increasing demand for biomedical engineers, especially in the Midwest United States, a reality which motivated the inception of a new KSU undergraduate degree in Biomedical Engineering starting in Fall 2018. The KSU IEEE EMBS student chapter can play a large role in the overall success of this new curriculum, and the projects and activities summarized in this paper are offered as examples to programs that may wish to benefit from an IEEE EMBS student chapter in a similar and meaningful way.
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http://dx.doi.org/10.1109/EMBC.2018.8512657DOI Listing
July 2018

Mohs Micrographic Surgery.

Facial Plast Surg Clin North Am 2019 Feb;27(1):15-34

Department of Dermatology, University of Colorado Hospital and School of Medicine, Mail Stop F703, 1665 North Aurora Court, Aurora, CO 80045, USA. Electronic address:

Mohs micrographic surgery (MMS) is the gold standard for treating various cutaneous tumors. MMS has evolved into a single-day, outpatient procedure. The tumor is excised, mapped, and processed with frozen, horizontal sections for immediate histologic evaluation. The process is repeated as necessary until the tumor is completely removed, with maximal conservation of normal tissue. Evaluation of 100% of the surgical margin allows for exceptional cure rates. The Mohs surgeon is trained in tumor excision, histopathology interpretation, and surgical reconstruction. The use of MMS is often part of a multidisciplinary approach to treating cutaneous tumors.
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http://dx.doi.org/10.1016/j.fsc.2018.08.002DOI Listing
February 2019

Utilization Patterns of Fellowship-Trained Mohs Surgeons in the Treatment of Merkel Cell Carcinoma.

Dermatol Surg 2019 04;45(4):610-611

Medical Student, University of Colorado School of Medicine, Aurora, Colorado Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000001636DOI Listing
April 2019

Use of sterile urine cups as sharps containers during Mohs micrographic surgery stages.

J Am Acad Dermatol 2018 Nov 3;79(5):e97-e98. Epub 2018 Feb 3.

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2018.01.044DOI Listing
November 2018

A Large Surgical Defect of the Central Forehead.

Dermatol Surg 2019 07;45(7):975-978

Departments of Otolaryngology, and.

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http://dx.doi.org/10.1097/DSS.0000000000001472DOI Listing
July 2019

Use of a Single Anatomic Donor Site for Harvesting a Full-Thickness Skin Graft and a Free Cartilage Graft for Nasal Defects.

Dermatol Surg 2018 07;44(7):1023-1024

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado Sorkin Dermatology, Denver, Colorado Department of Dermatology, Kaiser Permanente, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000001363DOI Listing
July 2018

Small Molecule Inhibitors of the Hedgehog Pathway in the Treatment of Basal Cell Carcinoma of the Skin.

Am J Clin Dermatol 2018 Apr;19(2):195-207

Department of Dermatology, University of Colorado School of Medicine, Mail Stop F703, 1665, North Aurora Court, Aurora, CO, 80045, USA.

Basal cell carcinoma (BCC) is the most common type of skin cancer, with rising incidence rates primarily attributed to an aging population and ultraviolet radiation exposure. While the majority of BCCs are localized and respond to standard therapies, a very small minority of these tumors become locally destructive or metastasize. These advanced BCCs may not be amenable to localized treatment with surgery and/or radiation therapy. Most BCCs result from mutations in key receptors in the Hedgehog (HH) signaling pathway. As a result, identification of drugs that inhibit the receptor Smoothened (SMO) in the HH pathway has resulted in novel therapeutic approaches to treating patients with advanced BCC. These HH-pathway inhibiting medications have shown efficacy in clinical trials, and two medications, vismodegib and sonidegib, have received FDA approval. However, several limitations of these drugs have been identified, including treatment-limiting adverse events, drug resistance, and the formation of additional malignancies. This paper aims to summarize the clinical trials leading to the approval of SMO inhibitors, as well as reviewing potential mechanisms driving tumor resistance and the formation of cutaneous squamous cell carcinomas. Strategies to overcome some of these challenges, including the development of drugs that inhibit other downstream targets in the HH pathway, are the subject of ongoing clinical trials.
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http://dx.doi.org/10.1007/s40257-017-0319-4DOI Listing
April 2018

Neuropraxia of the Spinal Accessory Nerve After Mohs Micrographic Surgery.

Dermatol Surg 2017 09;43(9):1192-1195

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado Department of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado Department of Dermatology, Baylor Scott and White Healthcare, Round Rock, Texas Department of Dermatology University of Colorado School of Medicine Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000001185DOI Listing
September 2017

Second Intention Healing for Large Surgical Defects of the Foot.

Dermatol Surg 2017 04;43(4):592-595

Department of Dermatology, Baylor Scott and White Healthcare, Round Rock, Texas Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000000933DOI Listing
April 2017

Large Surgical Defect of the Superior Ear.

Dermatol Surg 2017 05;43 Suppl 1:S115-S118

*Department of Dermatology, Baylor Scott and White Healthcare, Round Rock, Texas; †Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000000937DOI Listing
May 2017

ASDS Cosmetic Dermatologic Surgery Fellowship Milestones.

Dermatol Surg 2016 Oct;42(10):1164-73

*Department of Dermatology, McGaw Medical Center, Northwestern University, Chicago, Illinois; †SkinCare Physicians, Chestnut Hill, Massachusetts; ‡Dermatology Laser and Cosmetic Center, Massachusetts General Hospital, Boston, Massachusetts; §Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado; ‖Cosmetic Laser Dermatology-Goldman, Butterwick, Groff, Fabi & Wu, San Diego, California; ¶Westlake Dermatology and Cosmetic Surgery, Austin, Texas; #Laser & Skin Surgery Center of New York, New York, New York; **Skin Laser & Surgery Specialists of NY and NJ, Hackensack, New Jersey; ††Department of Dermatology, Mount Sinai School of Medicine, New York, New York; ‡‡Skin Associates of South Florida, Coral Gables, Florida; §§Department of Dermatology & Cutaneous Surgery, University of Miami, Coral Gables, Florida; ‖‖Connecticut Skin Institute, Stamford, Connecticut; ¶¶Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; ##Skin Care and Laser Physicians of Beverly Hills, Beverly Hills, California; ***Laser and Skin Surgery Center of Northern California, Sacramento, California; †††McDaniel Laser and Cosmetic Center, Virginia Beach, Virginia; ‡‡‡Department of Dermatology, UPMC Cosmetic Surgery and Skin Health Center, University of Pittsburgh, Sewickley, Pennsylvania; §§§Laser and Cosmetic Dermatology, Department of Dermatology, University of California, San Diego, California; ‖‖‖Gateway Aesthetic Institute and Laser Center, Salt Lake City, Utah; ¶¶¶Department of Dermatology, Case Western Reserve University, MetroHealth Systems, Cleveland, Ohio; ###Department of Dermatology, University of South Florida, Tampa, Florida; ****Maryland Laser, Skin & Vein Institute, Hunt Valley, Maryland; ††††Hollywood Dermatology and Cosmetic Surgery Specialists, Hollywood, Florida; ‡‡‡‡Department of Otolaryngology, Feinberg School of Medicine, Nor

Background: The American Council of Graduate Medical Education, which oversees much of postgraduate medical education in the United States, has championed the concept of "milestones," standard levels of achievement keyed to particular time points, to assess trainee performance during residency.

Objective: To develop a milestones document for the American Society for Dermatologic Surgery (ASDS) Cosmetic Dermatologic Surgery (CDS) fellowship program.

Methods: An ad hoc milestone drafting committee was convened that included members of the ASDS Accreditation Work Group and program directors of ASDS-approved Cosmetic Dermatologic Surgery (CDC) fellowship training programs. Draft milestones were circulated through email in multiple rounds until consensus was achieved.

Results: Thirteen milestones were developed in the 6 Accreditation Council for Graduate Medical Education (ACGME) competency areas, with 8 of these being patient-care milestones. Additional instructions for milestone administration more specific to the CDS fellowship than general ACGME instructions were also approved. Implementation of semiannual milestones was scheduled for the fellowship class entering in July 2018.

Conclusion: Milestones are now available for CDS fellowship directors to implement in combination with other tools for fellow evaluation.
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http://dx.doi.org/10.1097/DSS.0000000000000860DOI Listing
October 2016

Reconstruction of a Full-Thickness Nasal Defect.

Dermatol Surg 2017 11;43(11):1392-1396

*Both authors are affiliated with the Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000000829DOI Listing
November 2017

Plaque-Like Atypical Fibroxanthoma, A Rare Invasive Variant.

Dermatol Surg 2017 Jan;43(1):138-139

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1097/DSS.0000000000000834DOI Listing
January 2017

Cutaneous spindle cell carcinoma misdiagnosed as atypical fibroxanthoma based on immunohistochemical stains.

JAAD Case Rep 2015 Nov 2;1(6):392-4. Epub 2015 Nov 2.

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.jdcr.2015.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809406PMC
November 2015

Breast carcinoma masquerading as basal cell carcinoma of the nipple.

JAAD Case Rep 2015 Nov 2;1(6):361-3. Epub 2015 Oct 2.

Department of Dermatology, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.jdcr.2015.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809382PMC
November 2015
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