Publications by authors named "Mariaelena Pierobon"

52Publications

Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers.

Cell Rep 2020 Jun;31(11):107764

Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Charité Universitätsmedizin Berlin, Institute of Pathology, Laboratory of Molecular Tumor Pathology and Systems Biology, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393480PMC
June 2020

Utilization of Proteomic Technologies for Precision Oncology Applications.

Cancer Treat Res 2019 ;178:171-187

Center for Applied Proteomics and Molecular Medicine, George Mason University, 20110, Manassas, VA, USA.

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http://dx.doi.org/10.1007/978-3-030-16391-4_6DOI Listing
June 2019

Phosphoprotein-based drug target activation mapping for precision oncology: a view to the future.

Expert Rev Proteomics 2018 11 12;15(11):851-853. Epub 2018 Oct 12.

a Center for Applied Proteomics and Molecular Medicine, School of Systems Biology , George Mason University , Manassas , Virginia , USA.

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https://www.tandfonline.com/doi/full/10.1080/14789450.2018.1
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http://dx.doi.org/10.1080/14789450.2018.1531709DOI Listing
November 2018

Protein network construction using reverse phase protein array data.

Methods 2017 07 24;124:89-99. Epub 2017 Jun 24.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2017.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603262PMC
July 2017

Reverse Phase Protein Microarrays.

Methods Mol Biol 2017 ;1606:149-169

Center for Applied Proteomics and Molecular Medicine, George Mason University, 10920 George Mason Circle, MS 1A9, Manassas, VA, 20110, USA.

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http://dx.doi.org/10.1007/978-1-4939-6990-6_11DOI Listing
February 2018

Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.

Cancer Cell 2016 Jan 24;29(1):75-89. Epub 2015 Dec 24.

Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816652PMC
January 2016

Phosphorylation, Signaling, and Cancer: Targets and Targeting.

Biomed Res Int 2015 21;2015:601543. Epub 2015 Oct 21.

Department of Biomedical Sciences, University of Padova, Via U. Bassi 58/b, 35131 Padova, Italy.

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http://dx.doi.org/10.1155/2015/601543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631856PMC
August 2016

Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer.

J Clin Oncol 2015 Dec 21;33(34):4023-31. Epub 2015 Sep 21.

Ryan B. Corcoran, Eunice L. Kwak, and David P. Ryan, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA; Chloe E. Atreya, Adil Daud, and Alan P. Venook, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco; Omid Hamid, Angeles Clinic and Research Institute, Los Angeles, CA; Gerald S. Falchook, Sarah Cannon Research Institute at HealthONE, Denver; Wells A. Messersmith, University of Colorado Cancer Center and University of Colorado, Aurora, CO; Johanna C. Bendell, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Razelle Kurzrock and Scott Kopetz, University of Texas, MD Anderson Cancer Center, Houston, TX; Mariaelena Pierobon, Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA; Peng Sun, Elizabeth Cunningham, Shonda Little, Keith Orford, Monica Motwani, and Yuchen Bai, GlaxoSmithKline, Philadelphia, PA; and Kiran Patel, Incyte, Wilmington, DE.

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http://jco.ascopubs.org/content/33/34/4023.full.pdf
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http://jco.ascopubs.org/content/suppl/2015/09/21/JCO.2015.63
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2015.63.2471
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http://dx.doi.org/10.1200/JCO.2015.63.2471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669588PMC
December 2015

Lung cancer prognosis before and after recurrence in a population-based setting.

J Natl Cancer Inst 2015 Jun 23;107(6):djv059. Epub 2015 Mar 23.

Epidemiology Unit, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy (DC, PAB, ACP); Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA (MP); Genetic Epidemiology Branch (MP, MRo, AG, LG, NEC, MAT, MTL) and Biostatistics Branch (MHG, JL, SW), Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD; Department of Clinical Sciences and Community Health, Universita' degli Studi di Milano, Milan, Italy (MRu, PAB, ACP).

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http://dx.doi.org/10.1093/jnci/djv059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838060PMC
June 2015

Stratification of clear cell renal cell carcinoma by signaling pathway analysis.

Expert Rev Proteomics 2014 Apr 27;11(2):237-49. Epub 2014 Feb 27.

Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.

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http://dx.doi.org/10.1586/14789450.2014.893193DOI Listing
April 2014

Alcohol consumption and violence among Argentine adolescents.

J Pediatr (Rio J) 2013 Jan-Feb;89(1):100-7

Department of Global and Community Health, George Mason University, Fairfax, Virginia, USA.

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http://dx.doi.org/10.1016/j.jped.2013.02.015DOI Listing
August 2013

Reverse phase protein microarrays and their utility in drug development.

Methods Mol Biol 2013 ;986:187-214

Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA.

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http://dx.doi.org/10.1007/978-1-62703-311-4_13DOI Listing
August 2013

Obesity as a risk factor for triple-negative breast cancers: a systematic review and meta-analysis.

Breast Cancer Res Treat 2013 Jan 20;137(1):307-14. Epub 2012 Nov 20.

Department of Global and Community Health, George Mason University, 4400 University Drive, MSN 5B7, Fairfax, VA 22030, USA.

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http://dx.doi.org/10.1007/s10549-012-2339-3DOI Listing
January 2013

Microarray data analysis: comparing two population means.

Methods Mol Biol 2012 ;823:325-46

Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA.

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http://dx.doi.org/10.1007/978-1-60327-216-2_21DOI Listing
April 2012

Reverse-phase protein microarrays.

Methods Mol Biol 2012 ;823:215-35

Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA.

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http://dx.doi.org/10.1007/978-1-60327-216-2_14DOI Listing
April 2012

Reverse phase protein microarrays for clinical applications.

Methods Mol Biol 2011 ;785:3-12

Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA.

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http://cgp.iiarjournals.org/content/4/3/157.full.pdf
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http://link.springer.com/10.1007/978-1-61779-286-1_1
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http://dx.doi.org/10.1007/978-1-61779-286-1_1DOI Listing
January 2012

Mechanism of cell adaptation: when and how do cancer cells develop chemoresistance?

Cancer J 2011 Mar-Apr;17(2):89-95

Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA.

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https://insights.ovid.com/crossref?an=00130404-201103000-000
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http://dx.doi.org/10.1097/PPO.0b013e318212dd3dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558433PMC
July 2011

Protein pathway activation associated with sustained virologic response in patients with chronic hepatitis C treated with pegylated interferon (PEG-IFN) and ribavirin (RBV).

J Proteome Res 2011 Feb 4;10(2):774-9. Epub 2011 Jan 4.

Betty and Guy Beatty Center for Integrated Research, Inova Health System, Inova Fairfax Hospital, Falls Church, Virginia, 22042, USA.

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http://pubs.acs.org/doi/abs/10.1021/pr100923u
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http://dx.doi.org/10.1021/pr100923uDOI Listing
February 2011

Multiplexed Cell Signaling Analysis of Metastatic and Nonmetastatic Colorectal Cancer Reveals COX2-EGFR Signaling Activation as a Potential Prognostic Pathway Biomarker.

Clin Colorectal Cancer 2009 Mar;8(2):110-7

Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA Clinica Chirurgica II, Department of Oncological and Surgical Sciences, University of Padova, Italy.

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http://dx.doi.org/10.3816/CCC.2009.n.018DOI Listing
March 2009

Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy.

J Proteome Res 2008 Apr 8;7(4):1508-17. Epub 2008 Feb 8.

Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia 20110, USA.

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http://dx.doi.org/10.1021/pr7008127DOI Listing
April 2008

Laser capture microdissection technology.

Expert Rev Mol Diagn 2007 Sep;7(5):647-57

Center for Applied Proteomics & Molecular Medicine, George Mason University, Manassas, VA 20110, USA.

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http://dx.doi.org/10.1586/14737159.7.5.647DOI Listing
September 2007

Reverse-phase protein microarrays: application to biomarker discovery and translational medicine.

Expert Rev Mol Diagn 2007 Sep;7(5):625-33

George Mason University, Center for Applied Proteomics and Molecular Medicine, Manassas, VA 20110, USA.

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http://dx.doi.org/10.1586/14737159.7.5.625DOI Listing
September 2007