Publications by authors named "Maria Rosario Almeida"

47Publications

SERPINA1 modulates expression of amyloidogenic transthyretin.

Exp Cell Res 2020 Oct 5;395(2):112217. Epub 2020 Aug 5.

Medizinische Klinik B für Gastroenterologie und Hepatologie, Universitätsklinikum Münster, Münster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2020.112217DOI Listing
October 2020

C-reactive protein as a predictor of mild cognitive impairment conversion into Alzheimer's disease dementia.

Exp Gerontol 2020 Sep 16;138:111004. Epub 2020 Jun 16.

Neurology Department, Centro Hospitalar e Universitário de Coimbra, Praceta Prof. Mota Pinto, 3000-075 Coimbra, Portugal; Faculty of Medicine, University of Coimbra, R. Larga, 3004-504 Coimbra, Portugal; Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.exger.2020.111004DOI Listing
September 2020

Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.

Authors:
Katrina M Moore Jennifer Nicholas Murray Grossman Corey T McMillan David J Irwin Lauren Massimo Vivianna M Van Deerlin Jason D Warren Nick C Fox Martin N Rossor Simon Mead Martina Bocchetta Bradley F Boeve David S Knopman Neill R Graff-Radford Leah K Forsberg Rosa Rademakers Zbigniew K Wszolek John C van Swieten Lize C Jiskoot Lieke H Meeter Elise Gp Dopper Janne M Papma Julie S Snowden Jennifer Saxon Matthew Jones Stuart Pickering-Brown Isabelle Le Ber Agnès Camuzat Alexis Brice Paola Caroppo Roberta Ghidoni Michela Pievani Luisa Benussi Giuliano Binetti Bradford C Dickerson Diane Lucente Samantha Krivensky Caroline Graff Linn Öijerstedt Marie Fallström Håkan Thonberg Nupur Ghoshal John C Morris Barbara Borroni Alberto Benussi Alessandro Padovani Daniela Galimberti Elio Scarpini Giorgio G Fumagalli Ian R Mackenzie Ging-Yuek R Hsiung Pheth Sengdy Adam L Boxer Howie Rosen Joanne B Taylor Matthis Synofzik Carlo Wilke Patricia Sulzer John R Hodges Glenda Halliday John Kwok Raquel Sanchez-Valle Albert Lladó Sergi Borrego-Ecija Isabel Santana Maria Rosário Almeida Miguel Tábuas-Pereira Fermin Moreno Myriam Barandiaran Begoña Indakoetxea Johannes Levin Adrian Danek James B Rowe Thomas E Cope Markus Otto Sarah Anderl-Straub Alexandre de Mendonça Carolina Maruta Mario Masellis Sandra E Black Philippe Couratier Geraldine Lautrette Edward D Huey Sandro Sorbi Benedetta Nacmias Robert Laforce Marie-Pier L Tremblay Rik Vandenberghe Philip Van Damme Emily J Rogalski Sandra Weintraub Alexander Gerhard Chiadi U Onyike Simon Ducharme Sokratis G Papageorgiou Adeline Su Lyn Ng Amy Brodtmann Elizabeth Finger Rita Guerreiro Jose Bras Jonathan D Rohrer

Lancet Neurol 2020 02 3;19(2):145-156. Epub 2019 Dec 3.

Dementia Research Centre, Department of Neurodegenerative Disease, Institute of Neurology, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(19)30394-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007771PMC
February 2020

Increased CSF tau is associated with a higher risk of seizures in patients with Alzheimer's disease.

Epilepsy Behav 2019 09 2;98(Pt A):207-209. Epub 2019 Aug 2.

Neurology Department, Centro Hospitalário e Universitário de Coimbra, Praceta Prof. Mota Pinto, 3000-075 Coimbra, Portugal; Faculty of Medicine, University of Coimbra, R. Larga, 3004-504 Coimbra, Portugal; Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.yebeh.2019.06.033DOI Listing
September 2019

Uncovering the Neuroprotective Mechanisms of Curcumin on Transthyretin Amyloidosis.

Int J Mol Sci 2019 Mar 14;20(6). Epub 2019 Mar 14.

Molecular Neurobiology Group, IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.

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https://www.mdpi.com/1422-0067/20/6/1287
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http://dx.doi.org/10.3390/ijms20061287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471102PMC
March 2019

Increased risk of melanoma in C9ORF72 repeat expansion carriers: A case-control study.

Muscle Nerve 2019 03 27;59(3):362-365. Epub 2018 Dec 27.

CHUC, Serviço de Neurologia, Praceta Prof. Mota Pinto, 3000-075, Coimbra, Portugal.

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http://doi.wiley.com/10.1002/mus.26383
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http://dx.doi.org/10.1002/mus.26383DOI Listing
March 2019

Association between butyrylcholinesterase and cerebrospinal fluid biomarkers in Alzheimer's disease patients.

Neurosci Lett 2017 02 17;641:101-106. Epub 2017 Jan 17.

Laboratory of Neurochemistry, Coimbra University Hospital, Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.neulet.2017.01.036DOI Listing
February 2017

TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.

Hum Mutat 2017 03 19;38(3):297-309. Epub 2017 Jan 19.

Center for Molecular Neurology, VIB, Antwerp, Belgium.

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http://dx.doi.org/10.1002/humu.23161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324646PMC
March 2017

Characterization of an FTLD-PDB family with the coexistence of SQSTM1 mutation and hexanucleotide (G₄C₂) repeat expansion in C9orf72 gene.

Neurobiol Aging 2016 Apr 30;40:191.e1-191.e8. Epub 2015 Dec 30.

CNC-Center for Neuroscience and Cell Biology, Neurogenetics Department, University of Coimbra, Portugal; Neurology Department, Coimbra University Hospital, Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.12.015DOI Listing
April 2016

Cerebrospinal fluid Aβ40 is similarly reduced in patients with Frontotemporal Lobar Degeneration and Alzheimer's Disease.

J Neurol Sci 2015 Nov 10;358(1-2):308-16. Epub 2015 Sep 10.

Laboratory of Neurochemistry, Coimbra University Hospital, Portugal; Center for Neuroscience and Cell Biology, University of Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.jns.2015.09.022DOI Listing
November 2015

Transthyretin chemical chaperoning by flavonoids: Structure-activity insights towards the design of potent amyloidosis inhibitors.

Biochem Biophys Rep 2015 Sep 1;3:123-133. Epub 2015 Aug 1.

IBMC-Instituto de Biologia Molecular e Celular, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.bbrep.2015.07.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668852PMC
September 2015

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration.

Acta Neuropathol 2014 Sep 5;128(3):397-410. Epub 2014 Jun 5.

Department of Molecular Genetics, VIB, Antwerp, Belgium.

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http://dx.doi.org/10.1007/s00401-014-1298-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131163PMC
September 2014

Molecular tweezers targeting transthyretin amyloidosis.

Neurotherapeutics 2014 Apr;11(2):450-61

IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Rua do Campo Alegre, 823, 4150-180, Porto, Portugal.

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http://link.springer.com/10.1007/s13311-013-0256-8
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http://dx.doi.org/10.1007/s13311-013-0256-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996111PMC
April 2014

A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats.

Authors:
Julie van der Zee Ilse Gijselinck Lubina Dillen Tim Van Langenhove Jessie Theuns Sebastiaan Engelborghs Stéphanie Philtjens Mathieu Vandenbulcke Kristel Sleegers Anne Sieben Veerle Bäumer Githa Maes Ellen Corsmit Barbara Borroni Alessandro Padovani Silvana Archetti Robert Perneczky Janine Diehl-Schmid Alexandre de Mendonça Gabriel Miltenberger-Miltenyi Sónia Pereira José Pimentel Benedetta Nacmias Silvia Bagnoli Sandro Sorbi Caroline Graff Huei-Hsin Chiang Marie Westerlund Raquel Sanchez-Valle Albert Llado Ellen Gelpi Isabel Santana Maria Rosário Almeida Beatriz Santiago Giovanni Frisoni Orazio Zanetti Cristian Bonvicini Matthis Synofzik Walter Maetzler Jennifer Müller Vom Hagen Ludger Schöls Michael T Heneka Frank Jessen Radoslav Matej Eva Parobkova Gabor G Kovacs Thomas Ströbel Stayko Sarafov Ivailo Tournev Albena Jordanova Adrian Danek Thomas Arzberger Gian Maria Fabrizi Silvia Testi Eric Salmon Patrick Santens Jean-Jacques Martin Patrick Cras Rik Vandenberghe Peter Paul De Deyn Marc Cruts Christine Van Broeckhoven Julie van der Zee Ilse Gijselinck Lubina Dillen Tim Van Langenhove Jessie Theuns Stéphanie Philtjens Kristel Sleegers Veerle Bäumer Githa Maes Ellen Corsmit Marc Cruts Christine Van Broeckhoven Julie van der Zee Ilse Gijselinck Lubina Dillen Tim Van Langenhove Stéphanie Philtjens Jessie Theuns Kristel Sleegers Veerle Bäumer Githa Maes Marc Cruts Christine Van Broeckhoven Sebastiaan Engelborghs Peter P De Deyn Patrick Cras Sebastiaan Engelborghs Peter P De Deyn Mathieu Vandenbulcke Mathieu Vandenbulcke Barbara Borroni Alessandro Padovani Silvana Archetti Robert Perneczky Janine Diehl-Schmid Matthis Synofzik Walter Maetzler Jennifer Müller Vom Hagen Ludger Schöls Matthis Synofzik Walter Maetzler Jennifer Müller Vom Hagen Ludger Schöls Michael T Heneka Frank Jessen Alfredo Ramirez Delia Kurzwelly Carmen Sachtleben Wolfgang Mairer Alexandre de Mendonça Gabriel Miltenberger-Miltenyi Sónia Pereira Clara Firmo José Pimentel Raquel Sanchez-Valle Albert Llado Anna Antonell Jose Molinuevo Ellen Gelpi Caroline Graff Huei-Hsin Chiang Marie Westerlund Caroline Graff Anne Kinhult Ståhlbom Håkan Thonberg Inger Nennesmo Anne Börjesson-Hanson Benedetta Nacmias Silvia Bagnoli Sandro Sorbi Valentina Bessi Irene Piaceri Isabel Santana Beatriz Santiago Isabel Santana Maria Helena Ribeiro Maria Rosário Almeida Catarina Oliveira João Massano Carolina Garret Paula Pires Giovanni Frisoni Orazio Zanetti Cristian Bonvicini Stayko Sarafov Ivailo Tournev Albena Jordanova Ivailo Tournev Gabor G Kovacs Thomas Ströbel Michael T Heneka Frank Jessen Alfredo Ramirez Delia Kurzwelly Carmen Sachtleben Wolfgang Mairer Frank Jessen Radoslav Matej Eva Parobkova Adrian Danel Thomas Arzberger Gian Maria Fabrizi Silvia Testi Sergio Ferrari Tiziana Cavallaro Eric Salmon Patrick Santens Patrick Cras

Hum Mutat 2013 Feb 4;34(2):363-73. Epub 2013 Jan 4.

Department of Molecular Genetics, VIB, Antwerp, Belgium.

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http://dx.doi.org/10.1002/humu.22244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638346PMC
February 2013

Dietary curcumin counteracts extracellular transthyretin deposition: insights on the mechanism of amyloid inhibition.

Biochim Biophys Acta 2013 Jan 13;1832(1):39-45. Epub 2012 Oct 13.

IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1016/j.bbadis.2012.10.007DOI Listing
January 2013

Clearance of extracellular misfolded proteins in systemic amyloidosis: experience with transthyretin.

FEBS Lett 2012 Aug 20;586(18):2891-6. Epub 2012 Jul 20.

IBMC, Instituto de Biologia Molecular e Celular, Universidade do Porto, Portugal.

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http://dx.doi.org/10.1016/j.febslet.2012.07.029DOI Listing
August 2012

Natural polyphenols as modulators of TTR amyloidogenesis: in vitro and in vivo evidences towards therapy.

Amyloid 2012 Jun;19 Suppl 1:39-42

Grupo de Neurobiologia Molecular, IBMC - Instituto de Biologia Molecular e Celular, and Departamento de BiologiaMolecular, ICBAS − Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.3109/13506129.2012.668502DOI Listing
June 2012

Epigallocatechin-3-gallate as a potential therapeutic drug for TTR-related amyloidosis: "in vivo" evidence from FAP mice models.

PLoS One 2012 10;7(1):e29933. Epub 2012 Jan 10.

Grupo de Neurobiologia Molecular, IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029933PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254632PMC
May 2012

Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation.

FEBS Lett 2011 Aug 2;585(15):2424-30. Epub 2011 Jul 2.

Grupo de Neurobiologia Molecular, IBMC-Instituto de Biologia Molecular e Celular, Porto, Portugal.

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http://dx.doi.org/10.1016/j.febslet.2011.06.030DOI Listing
August 2011

Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity.

FEBS Lett 2009 Nov 25;583(22):3569-76. Epub 2009 Oct 25.

Grupo de Neurobiologia Molecular, Instituto de Biologia Molecular e Celular, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1016/j.febslet.2009.10.062DOI Listing
November 2009

Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors.

Bioorg Med Chem Lett 2009 Sep 6;19(17):5270-3. Epub 2009 Mar 6.

Laboratori de Química Orgànica, Facultat de Farmàcia, Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bmcl.2009.03.004DOI Listing
September 2009

Iron homeostasis and H63D mutations in alcoholics with and without liver disease.

World J Gastroenterol 2009 Jan;15(1):106-11

Unidade de Nutrição e Metabolismo, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Portugal.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653287PMC
http://dx.doi.org/10.3748/wjg.15.106DOI Listing
January 2009

Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy.

Biochim Biophys Acta 2008 Sep 3;1782(9):517-22. Epub 2008 Jun 3.

Instituto de Biologia Molecular e Celular-IBMC, Porto, Portugal.

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http://dx.doi.org/10.1016/j.bbadis.2008.05.005DOI Listing
September 2008

Iodination of salicylic acid improves its binding to transthyretin.

Biochim Biophys Acta 2008 Mar 3;1784(3):512-7. Epub 2007 Dec 3.

ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Largo Prof. Abel Salazar, 2, 4099-003 Porto, Portugal.

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http://dx.doi.org/10.1016/j.bbapap.2007.11.014DOI Listing
March 2008

Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative.

Biochem J 2004 Jul;381(Pt 2):351-6

Molecular Neurobiology Unit, Instituto de Biologia Molecular e Celular e Departamento de Biologia Molecular, ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4150-180 Porto, Portugal.

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http://dx.doi.org/10.1042/BJ20040011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133839PMC
July 2004