Publications by authors named "Maria Rosa Loffredo"

16Publications

The Antimicrobial Peptide Temporin G: Anti-Biofilm, Anti-Persister Activities, and Potentiator Effect of Tobramycin Efficacy Against .

Authors:
Bruno Casciaro Maria Rosa Loffredo Floriana Cappiello Guendalina Fabiano Luisa Torrini Maria Luisa Mangoni

Int J Mol Sci 2020 Dec 10;21(24). Epub 2020 Dec 10.

Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

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December 2020

-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors.

Authors:
Deborah Quaglio Maria Luisa Mangoni Roberta Stefanelli Silvia Corradi Bruno Casciaro Valeria Vergine Federica Lucantoni Luca Cavinato Silvia Cammarone Maria Rosa Loffredo Floriana Cappiello Andrea Calcaterra Silvia Erazo Francesca Ghirga Mattia Mori Francesco Imperi Fiorentina Ascenzioni Bruno Botta

J Org Chem 2020 08 10;85(16):10891-10901. Epub 2020 Aug 10.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

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August 2020

Naturally-Occurring Alkaloids of Plant Origin as Potential Antimicrobials against Antibiotic-Resistant Infections.

Authors:
Bruno Casciaro Laura Mangiardi Floriana Cappiello Isabella Romeo Maria Rosa Loffredo Antonia Iazzetti Andrea Calcaterra Antonella Goggiamani Francesca Ghirga Maria Luisa Mangoni Bruno Botta Deborah Quaglio

Molecules 2020 Aug 9;25(16). Epub 2020 Aug 9.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

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August 2020

Frog Skin-Derived Peptides Against Correlation between Antibacterial and Cytotoxic Activities.

Authors:
Bruno Casciaro Maria Rosa Loffredo Floriana Cappiello Walter Verrusio Vito Domenico Corleto Maria Luisa Mangoni

Antibiotics (Basel) 2020 Jul 26;9(8). Epub 2020 Jul 26.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

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July 2020

The Revaluation of Plant-Derived Terpenes to Fight Antibiotic-Resistant Infections.

Authors:
Floriana Cappiello Maria Rosa Loffredo Cristina Del Plato Silvia Cammarone Bruno Casciaro Deborah Quaglio Maria Luisa Mangoni Bruno Botta Francesca Ghirga

Antibiotics (Basel) 2020 Jun 13;9(6). Epub 2020 Jun 13.

Center For Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy.

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June 2020

A novel colistin adjuvant identified by virtual screening for ArnT inhibitors.

Authors:
Francesca Ghirga Roberta Stefanelli Luca Cavinato Alessandra Lo Sciuto Silvia Corradi Deborah Quaglio Andrea Calcaterra Bruno Casciaro Maria Rosa Loffredo Floriana Cappiello Patrizia Morelli Alberto Antonelli Gian Maria Rossolini Marialuisa Mangoni Carmine Mancone Bruno Botta Mattia Mori Fiorentina Ascenzioni Francesco Imperi

J Antimicrob Chemother 2020 Sep;75(9):2564-2572

Department of Sciences, 'Department of Excellence 2018 - 2022', Roma Tre University, Rome, Italy.

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September 2020

Structural Elucidation and Antimicrobial Characterization of Novel Diterpenoids from var. .

Authors:
Deborah Quaglio Silvia Corradi Silvia Erazo Valeria Vergine Simone Berardozzi Fabio Sciubba Floriana Cappiello Maria Elisa Crestoni Fiorentina Ascenzioni Francesco Imperi Franco Delle Monache Mattia Mori Maria Rosa Loffredo Francesca Ghirga Bruno Casciaro Bruno Botta Maria Luisa Mangoni

ACS Med Chem Lett 2020 May 30;11(5):760-765. Epub 2020 Jan 30.

Department of Biochemical Sciences, Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, P.le Aldo Moro 5 00185, Rome, Italy.

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May 2020

Nigritanine as a New Potential Antimicrobial Alkaloid for the Treatment of -Induced Infections.

Authors:
Bruno Casciaro Andrea Calcaterra Floriana Cappiello Mattia Mori Maria Rosa Loffredo Francesca Ghirga Maria Luisa Mangoni Bruno Botta Deborah Quaglio

Toxins (Basel) 2019 09 1;11(9). Epub 2019 Sep 1.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, Rome 00185, Italy.

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September 2019

The Potential of Frog Skin Peptides for Anti-Infective Therapies: The Case of Esculentin-1a(1-21)NH2.

Authors:
Bruno Casciaro Floriana Cappiello Maria Rosa Loffredo Francesca Ghirga Maria Luisa Mangoni

Curr Med Chem 2020 ;27(9):1405-1419

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.

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May 2020

Inhibition of Pseudomonas aeruginosa biofilm formation and expression of virulence genes by selective epimerization in the peptide Esculentin-1a(1-21)NH.

Authors:
Bruno Casciaro Qiao Lin Sergii Afonin Maria Rosa Loffredo Valeria de Turris Volker Middel Anne S Ulrich YuanPu Peter Di Maria Luisa Mangoni

FEBS J 2019 10 13;286(19):3874-3891. Epub 2019 Jun 13.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Italy.

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October 2019

The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L.

Authors:
Elisabetta Buommino Alfonso Carotenuto Ignazio Antignano Rosa Bellavita Bruno Casciaro Maria Rosa Loffredo Francesco Merlino Ettore Novellino Maria Luisa Mangoni Francesca Paola Nocera Diego Brancaccio Pasqualina Punzi Daniela Roversi Raffaele Ingenito Elisabetta Bianchi Paolo Grieco

ChemMedChem 2019 07 3;14(13):1283-1290. Epub 2019 Jun 3.

Department of Pharmacy, University of Naples "Federico II", Naples, 80131, Italy.

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July 2019

Poly(lactide- co-glycolide) Nanoparticles for Prolonged Therapeutic Efficacy of Esculentin-1a-Derived Antimicrobial Peptides against Pseudomonas aeruginosa Lung Infection: in Vitro and in Vivo Studies.

Authors:
Bruno Casciaro Ivana d'Angelo Xiaoping Zhang Maria Rosa Loffredo Gemma Conte Floriana Cappiello Fabiana Quaglia Yuan-Pu Peter Di Francesca Ungaro Maria Luisa Mangoni

Biomacromolecules 2019 05 23;20(5):1876-1888. Epub 2019 Apr 23.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences "A. Rossi Fanelli" , Sapienza University of Rome , via degli Apuli, 9 , 00185 Rome , Italy.

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May 2019

Esculentin-1a Derived Antipseudomonal Peptides: Limited Induction of Resistance and Synergy with Aztreonam.

Authors:
Bruno Casciaro Maria Rosa Loffredo Vincenzo Luca Walter Verrusio Mauro Cacciafesta Maria Luisa Mangoni

Protein Pept Lett 2018 ;25(12):1155-1162

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, via degli Apuli, 9, 00185, Rome, Italy.

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February 2019

Esculentin-1a derived peptides kill Pseudomonas aeruginosa biofilm on soft contact lenses and retain antibacterial activity upon immobilization to the lens surface.

Authors:
Bruno Casciaro Debarun Dutta Maria Rosa Loffredo Stefania Marcheggiani Alison M McDermott Mark Dp Willcox Maria Luisa Mangoni

Biopolymers 2017 Oct 31. Epub 2017 Oct 31.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.

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October 2017

Membrane perturbing activities and structural properties of the frog-skin derived peptide Esculentin-1a(1-21)NH and its Diastereomer Esc(1-21)-1c: Correlation with their antipseudomonal and cytotoxic activity.

Authors:
Maria Rosa Loffredo Anirban Ghosh Nicole Harmouche Bruno Casciaro Vincenzo Luca Annalisa Bortolotti Floriana Cappiello Lorenzo Stella Anirban Bhunia Burkhard Bechinger Maria Luisa Mangoni

Biochim Biophys Acta Biomembr 2017 Dec 12;1859(12):2327-2339. Epub 2017 Sep 12.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Rome, via degli Apuli, 9, 00185, Italy. Electronic address:

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December 2017

Glycine-replaced derivatives of [Pro,DLeu]TL, a temporin L analogue: Evaluation of antimicrobial, cytotoxic and hemolytic activities.

Authors:
Francesco Merlino Alfonso Carotenuto Bruno Casciaro Francesca Martora Maria Rosa Loffredo Antonio Di Grazia Ali M Yousif Diego Brancaccio Luciana Palomba Ettore Novellino Massimiliano Galdiero Maria Rosaria Iovene Maria L Mangoni Paolo Grieco

Eur J Med Chem 2017 Oct 21;139:750-761. Epub 2017 Aug 21.

Department of Pharmacy, University of Naples 'Federico II', Naples, 80131, Italy. Electronic address:

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October 2017