Publications by authors named "Maria Paola Martelli"

66Publications

How I diagnose and treat NPM1-mutated AML.

Blood 2020 Nov 10. Epub 2020 Nov 10.

Hematology, CREO, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1182/blood.2020008211DOI Listing
November 2020

Enasidenib and ivosidenib in AML.

Minerva Med 2020 Oct 21;111(5):411-426. Epub 2020 Sep 21.

Unit of Hematology, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Forlì-Cesena, Italy.

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http://dx.doi.org/10.23736/S0026-4806.20.07024-XDOI Listing
October 2020

NPM1-mutated acute myeloid leukemia: from bench to bedside.

Blood 2020 Oct;136(15):1707-1721

Institute of Hematology, Centro Ricerche Emato-Oncologiche, Ospedale S. Maria della Misericordia, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1182/blood.2019004226DOI Listing
October 2020

Flower cells of tropical descent: a challenging case of adult T-cell leukemia/lymphoma.

Tumori 2019 Dec 1;105(6):NP38-NP42. Epub 2019 May 1.

Hematology and Clinical Immunology, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1177/0300891619847756DOI Listing
December 2019

Getting away with phase transition: NPM1-mutated bone myeloid sarcoma mimicking Ewing sarcoma.

Ann Hematol 2019 Aug 16;98(8):2017-2018. Epub 2019 Mar 16.

Institute of Haematology and Centre of Haemato-Oncology Research (CREO), University and Hospital of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1007/s00277-019-03664-4DOI Listing
August 2019

Mutant NPM1 Maintains the Leukemic State through HOX Expression.

Cancer Cell 2018 09;34(3):499-512.e9

Stem Cell and Regenerative Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Center for Cell and Gene Therapy, Texas Children's Hospital and Houston Methodist Hospital, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159911PMC
September 2018

BRAF V600E mutation in hairy cell leukemia: from bench to bedside.

Blood 2016 10 23;128(15):1918-1927. Epub 2016 Aug 23.

Institute of Hematology and Center for Hemato-Oncology Research (CREO), University and Hospital of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1182/blood-2016-07-418434DOI Listing
October 2016

Impact of genomics in the clinical management of patients with cytogenetically normal acute myeloid leukemia.

Best Pract Res Clin Haematol 2015 Jun-Sep;28(2-3):90-7. Epub 2015 Oct 22.

Institute of Hematology-Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Italy.

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http://dx.doi.org/10.1016/j.beha.2015.10.005DOI Listing
September 2016

Dactinomycin in NPM1-Mutated Acute Myeloid Leukemia.

N Engl J Med 2015 Sep;373(12):1180-2

University of Perugia, Perugia, Italy

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http://www.nejm.org/doi/10.1056/NEJMc1509584
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http://dx.doi.org/10.1056/NEJMc1509584DOI Listing
September 2015

Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics.

Br J Haematol 2015 Aug 19;170(3):305-22. Epub 2015 Apr 19.

Institute of Haematology-CREO (Centro di Ricerche Emato-Oncologiche), Ospedale S. Maria Misericordia, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1111/bjh.13409DOI Listing
August 2015

Pharmacological modulation of caspase-8 in thymus-related medical conditions.

J Pharmacol Exp Ther 2014 Oct 24;351(1):18-24. Epub 2014 Jul 24.

Foligno Nurse School, Department of Medicine (N.P.), Section of Hematology (M.P.M.), Section of Pharmacology (E.A., C.R., D.V.D.), Department of Medicine, Section of Onco-Hematology, Hospital S. Maria, Terni, Department of Surgery (A.M.L.), University of Perugia, Perugia, Italy; Autoimmunity Laboratory, Immunology and Pharmacotherapy Area, Bambin Gesù Children's Hospital IRCCS, Rome, Italy (A.F.); and Institute of Chemistry, Vietnam Academy of Science and Technology, Cau Giay, Hanoi, Vietnam (T.T.T.)

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http://dx.doi.org/10.1124/jpet.114.216572DOI Listing
October 2014

Mutational landscape of AML with normal cytogenetics: biological and clinical implications.

Blood Rev 2013 Jan 20;27(1):13-22. Epub 2012 Dec 20.

Institute of Hematology, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/j.blre.2012.11.001DOI Listing
January 2013

NPM1-mutated AML: targeting by disassembling.

Blood 2011 Sep;118(11):2936-8

University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1182/blood-2011-07-366146DOI Listing
September 2011

Acute myeloid leukemia with mutated nucleophosmin (NPM1): any hope for a targeted therapy?

Blood Rev 2011 Nov 2;25(6):247-54. Epub 2011 Jul 2.

Institute of Hematology, Strada Sant'Andrea delle Fratte, University of Perugia, 06122 Perugia, Italy.

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http://dx.doi.org/10.1016/j.blre.2011.06.001DOI Listing
November 2011

New classification of acute myeloid leukemia and precursor-related neoplasms: changes and unsolved issues.

Discov Med 2010 Oct;10(53):281-92

Institute of Hematology, University of Perugia, Perugia, Italy.

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October 2010

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

Blood 2011 Jan 28;117(4):1109-20. Epub 2010 Oct 28.

Institute of Hematology, University of Perugia, Ospedale S. Maria della Misericordia, S. Andrea delle Fratte, Perugia, Italy.

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http://dx.doi.org/10.1182/blood-2010-08-299990DOI Listing
January 2011

Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives.

Curr Opin Oncol 2009 Nov;21(6):573-81

Institute of Hematology, University of Perugia, Perugia, Italy. to Top

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CCO.0b013e3283313dfaDOI Listing
November 2009

Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias.

Haematologica 2007 Apr;92(4):519-32

Section of Haematology and Immunology, University of Perugia, IBit Foundation, Perugia, Italy.

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http://dx.doi.org/10.3324/haematol.11007DOI Listing
April 2007

Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells.

Mol Immunol 2007 Mar 18;44(9):2469-80. Epub 2006 Dec 18.

Laboratory of Lymphocyte Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016158900600631
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http://dx.doi.org/10.1016/j.molimm.2006.09.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1945820PMC
March 2007

Relevance of CD79a expression for T-cell lineage attribution in CD7+/CD3- acute lymphoblastic leukemia.

Haematologica 2002 Oct;87(10):ELT41

Dipartimento di Biotecnologie Cellulari ed Ematologia, Sezione di Ematologia, University La Sapienza, Rome, Italy.

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October 2002