Publications by authors named "Maria Nesterova"

50 Publications

Pde8b haploinsufficiency in mice is associated with modest adrenal defects, impaired steroidogenesis, and male infertility, unaltered by concurrent PKA or Wnt activation.

Mol Cell Endocrinol 2021 02 15;522:111117. Epub 2020 Dec 15.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology & Genetics (PDEGEN), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD, 20892, USA. Electronic address:

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February 2021

Deformation and fracture of crystalline tungsten and fabrication of composite STM probes.

Ultramicroscopy 2020 Nov 22;218:113083. Epub 2020 Jul 22.

Institute of Solid State Physics, Russian Academy of Sciences, Chernogolovka, Moscow district 142432, Russia; School of Physics, Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, Dublin 2, Ireland. Electronic address:

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November 2020

Acute vs chronic exposure to high fat diet leads to distinct regulation of PKA.

J Mol Endocrinol 2017 07 18;59(1):1-12. Epub 2017 Apr 18.

Section on Endocrinology and GeneticsProgram on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

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July 2017

Celecoxib treatment of fibrous dysplasia (FD) in a human FD cell line and FD-like lesions in mice with protein kinase A (PKA) defects.

Mol Cell Endocrinol 2017 01 4;439:165-174. Epub 2016 Aug 4.

Section on Endocrinology and Genetics (SEGEN), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD 20892, USA. Electronic address:

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January 2017

Bilateral Adrenal Hyperplasia as a Possible Mechanism for Hyperandrogenism in Women With Polycystic Ovary Syndrome.

J Clin Endocrinol Metab 2016 09 23;101(9):3353-60. Epub 2016 Jun 23.

Section on Endocrinology and Genetics (E.G., M.L., M.K., C.L., M.N., M.S., P.X., C.A.S.), and Pediatric Endocrinology Inter-Institute Training Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and Department of Radiology (E.T.), Clinical Center, National Institutes of Health, Bethesda, Maryland 20892; Division of Pediatric Endocrinology (E.G.), Georgetown University Medical Center, Washington, DC 20007; Biostatistics and Clinical Epidemiology Service (N.S.), National Institutes of Health Clinical Center, Bethesda, MD; Division of Pediatric Endocrinology (D.K., S.T.), Infants and Children's Hospital of Brooklyn at Maimonides and Children and Hospital at Downstate, State University of New York, Brooklyn, New York 11219. and Department of Endocrinology (A.D.), Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

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September 2016

Studies of mice with cyclic AMP-dependent protein kinase (PKA) defects reveal the critical role of PKA's catalytic subunits in anxiety.

Behav Brain Res 2016 07 16;307:1-10. Epub 2016 Mar 16.

Section on Endocrinology and Genetics, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD 20892, United States.

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July 2016

Haploinsufficiency for either one of the type-II regulatory subunits of protein kinase A improves the bone phenotype of Prkar1a+/- mice.

Hum Mol Genet 2015 Nov 5;24(21):6080-92. Epub 2015 Aug 5.

Section on Endocrinology and Genetics (SEGEN), Program on Developmental Endocrinology & Genetics (PDEGEN), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD),

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November 2015

Is IGSF1 involved in human pituitary tumor formation?

Endocr Relat Cancer 2015 Feb 19;22(1):47-54. Epub 2014 Dec 19.

Section on Endocrinology and GeneticsProgram on Developmental Endocrinology and Genetics (PDEGEN) Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, NIH-Clinical Research Center, 10 Center Drive, Building 10, Room 1-3330, MSC1103, Bethesda, Maryland 20892, USAGroup for Advanced Molecular InvestigationGraduate Program in Health Science, Medical School, Pontificia Universidade Catolica do Paraná, Curitiba 80215, BrazilDepartment of Pharmacology and TherapeuticsMcGill University, Montréal, Québec, Canada H3G 1Y6Pediatric Endocrinology Inter-institute Training ProgramEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, Maryland 20892, USAThe Liggins InstituteUniversity of Auckland, Auckland 1023, New ZealandTaranaki Base HospitalNew Plymouth 4310, New ZealandAuckland City Hospital & Greenlane Clinical CentreAuckland 1142, New ZealandDepartment of NeurosurgeryUniversity of Virginia Health Sciences Center, University of Virginia, Charlottesville, Virginia 22904, USASurgical Neurology BranchNational Institute for Neurological Diseases and Stroke (NINDS), National Institutes of Health, Bethesda, Maryland 20892, USA Departments ofEndocrinology and Metabolic DisordersPediatricsLeiden University Medical Center, Leiden 2333, The Netherlands Section on Endocrinology and GeneticsProgram on Developmental Endocrinology and Genetics (PDEGEN) Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, NIH-Clinical Research Center, 10 Center Drive, Building 10, Room 1-3330, MSC1103, Bethesda, Maryland 20892, USAGroup for Advanced Molecular InvestigationGraduate Program in Health Science, Medical School, Pontificia Universidade Catolica do Paraná, Curitiba 80215, BrazilDepartment of Pharmacology and TherapeuticsMcGill University, Montréal, Québec, Canada H3G 1Y6Pediatric

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February 2015

Differentially regulated protein kinase A (PKA) activity in adipose tissue and liver is associated with resistance to diet-induced obesity and glucose intolerance in mice that lack PKA regulatory subunit type IIα.

Endocrinology 2014 Sep 10;155(9):3397-408. Epub 2014 Jun 10.

Section on Endocrinology and Genetics (E.L., M.N., E.S., S.A.M., C.A.S.), Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Biostatistics and Clinical Epidemiology Service (N.S.), CC, National Institutes of Health, Mouse Metabolism Core Laboratory (T.C., O.G.), National Institute of Diabetes and Digestive and Kidney Diseases, and Eunice Kennedy Shriver National Institute of Child Health and Human Development intramural Summer Student Program (S.A.M.), Bethesda, Maryland 20892.

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September 2014

Does somatostatin have a role in the regulation of cortisol secretion in primary pigmented nodular adrenocortical disease (ppnad)? a clinical and in vitro investigation.

J Clin Endocrinol Metab 2014 May 10;99(5):E891-901. Epub 2014 Feb 10.

INSERM Unité 982 (Z.B., E.L., H.L.), Laboratory of Neuronal and Neuroendocrine Differentiation and Communication, Institute for Research and Innovation in Biomedicine, University of Rouen, 76821 Rouen, France; Section on Endocrinology and Genetics (P.X., D.A., C.G., M.N., R.C., C.A.S.), Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Pediatric Endocrinology Inter-Institute Training Program (M.F.K., C.A.S.), National Institute of Child Health and Human Development, National Institutes of Health, and Clinical Center (N.S.), National Institutes of Health, Bethesda, Maryland 20892; Erasmus Medical Center (L.J.H.), 3015 GE Rotterdam, The Netherlands; and Department of Endocrinology (H.L.), Institute for Research and Innovation in Biomedicine, University Hospital of Rouen, 76031 Rouen, France.

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May 2014

Differences in adiposity in Cushing syndrome caused by PRKAR1A mutations: clues for the role of cyclic AMP signaling in obesity and diagnostic implications.

J Clin Endocrinol Metab 2014 Feb 18;99(2):E303-10. Epub 2013 Nov 18.

Section on Endocrinology and Genetics (E.L., A.R., M.L., E.G., M.K., C.L., M.d.l.L.S., M.N., C.A.S.), Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Inter-Institute Pediatric Endocrinology Training Program (E.G.), and Department of Diagnostic Radiology (N.P., C.A.S.), Clinical Research Center, National Institutes of Health, Bethesda, Maryland 20892; and Service d'Endocrinologie Pédiatrique (A.R.), Université Paris-Sud 11, Hôpital Bicêtre, 94270 Le Kremlin-Bicêtre, France.

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February 2014

Cyclic AMP and c-KIT signaling in familial testicular germ cell tumor predisposition.

J Clin Endocrinol Metab 2013 Aug 14;98(8):E1393-400. Epub 2013 Jun 14.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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August 2013

Comprehensive analysis of LC/MS data using pseudocolor plots.

J Am Soc Mass Spectrom 2013 Feb 3;24(2):230-7. Epub 2013 Jan 3.

National Institutes of Health, Bethesda, MD 20892, USA.

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February 2013

Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP-specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours.

Clin Endocrinol (Oxf) 2012 Aug;77(2):195-9

Section on Endocrinology and Genetics and Pediatric Endocrinology Training Program, both at Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1103, USA.

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August 2012

Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations.

J Clin Endocrinol Metab 2012 Apr 18;97(4):E687-93. Epub 2012 Jan 18.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Building 10, CRC, Room 1-3330, 10 Center Drive, MSC1103, Bethesda, Maryland 20892, USA.

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April 2012

In vitro studies of novel PRKAR1A mutants that extend the predicted RIα protein sequence into the 3'-untranslated open reading frame: proteasomal degradation leads to RIα haploinsufficiency and Carney complex.

J Clin Endocrinol Metab 2012 Mar 28;97(3):E496-502. Epub 2011 Dec 28.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Building 10, CRC, Room 1-3330, 10 Center Drive, MSC1103, Bethesda, Maryland 20892, USA.

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March 2012

Succinate dehydrogenase (SDH) D subunit (SDHD) inactivation in a growth-hormone-producing pituitary tumor: a new association for SDH?

J Clin Endocrinol Metab 2012 Mar 14;97(3):E357-66. Epub 2011 Dec 14.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Building 10, CRC, Room 1-3330, 10 Center Drive, MSC1103, Bethesda, Maryland 20892, USA.

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March 2012

Anxiety phenotype in mice that overexpress protein kinase A.

Psychoneuroendocrinology 2012 Jun 22;37(6):836-43. Epub 2011 Oct 22.

Section on Endocrinology and Genetics, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD 20892, USA.

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June 2012

Role of nonselective cation channels in spontaneous and protein kinase A-stimulated calcium signaling in pituitary cells.

Am J Physiol Endocrinol Metab 2011 Aug 17;301(2):E370-9. Epub 2011 May 17.

National Institute of Child Health and Human Development/NIH, 49 Convent Dr., Bethesda, MD 20892-4510, USA.

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August 2011

Integrated genomic analysis of nodular tissue in macronodular adrenocortical hyperplasia: progression of tumorigenesis in a disorder associated with multiple benign lesions.

J Clin Endocrinol Metab 2011 Apr 20;96(4):E728-38. Epub 2011 Jan 20.

Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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April 2011

Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors.

Hum Mol Genet 2011 Jan 11;20(1):165-75. Epub 2010 Oct 11.

PDEGEN, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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January 2011

Phosphodiesterase 11A (PDE11A) genetic variants may increase susceptibility to prostatic cancer.

J Clin Endocrinol Metab 2011 Jan 29;96(1):E135-40. Epub 2010 Sep 29.

Section of Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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January 2011

Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone.

Proc Natl Acad Sci U S A 2010 May 26;107(19):8683-8. Epub 2010 Apr 26.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics and Pediatric Endocrinology Inter-institute Training Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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May 2010

Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling.

Hum Mol Genet 2010 Apr 15;19(8):1387-98. Epub 2010 Jan 15.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice KennedyShriver, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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April 2010

Association of the M1V PRKAR1A mutation with primary pigmented nodular adrenocortical disease in two large families.

J Clin Endocrinol Metab 2010 Jan 13;95(1):338-42. Epub 2009 Nov 13.

Department of Endocrinology and Metabolism and Center for Human, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

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January 2010

8-Cl-adenosine inhibits proliferation and causes apoptosis in B-lymphocytes via protein kinase A-dependent and independent effects: implications for treatment of Carney complex-associated tumors.

J Clin Endocrinol Metab 2009 Oct 22;94(10):4061-9. Epub 2009 Sep 22.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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October 2009

Functional phosphodiesterase 11A mutations may modify the risk of familial and bilateral testicular germ cell tumors.

Cancer Res 2009 Jul 23;69(13):5301-6. Epub 2009 Jun 23.

Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 10 Center Drive, CRC, Room 1-3330, Bethesda, MD 20892, USA.

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July 2009