Publications by authors named "Maria Martinez-Lage"

64Publications

Episodic Visual Distortions and Stroke-Like Symptoms in a 56-Year-Old Man With Intravascular Lymphoma.

J Neuroophthalmol 2020 06;40(2):265-270

Division of Neuro-Ophthalmology (BKC, VPD, KAAD, DMC), Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts; and Departments of Neurology (BKC), Pathology (MML), and Radiology (HRK), Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1097/WNO.0000000000000900DOI Listing
June 2020

Case 31-2019: A 45-Year-Old Woman with Headache and Somnolence.

N Engl J Med 2019 10;381(15):1459-1470

From the Department of Medicine, Warren Alpert Medical School of Brown University, Providence, RI (A.R.T.); the Department of Medicine, Newton-Wellesley Hospital, Newton, MA (E.L.B.); and the Departments of Radiology (K.A.B.) and Pathology (M.M.-L.), Massachusetts General Hospital, the Department of Medicine, Brigham and Women's Hospital (F.M.M.), and the Departments of Radiology (K.A.B.), Medicine (F.M.M.), and Pathology (M.M.-L.), Harvard Medical School - all in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1904045DOI Listing
October 2019

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.

Cell 2019 08 18;178(4):835-849.e21. Epub 2019 Jul 18.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703186PMC
August 2019

Treatment-induced brain tissue necrosis: a clinical challenge in neuro-oncology.

Neuro Oncol 2019 09;21(9):1118-1130

MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1093/neuonc/noz048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594558PMC
September 2019

Primary diffuse large B-cell lymphoma of the CNS: a rare case of spontaneous remission.

Int J Hematol Oncol 2017 Nov 20;6(3):69-73. Epub 2017 Nov 20.

Abramson Cancer Center, Hospital of the University of Pennsylvania, 12 South PCAM, 3400 Civic Center Blvd, PA 19104, USA.

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http://dx.doi.org/10.2217/ijh-2017-0009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171994PMC
November 2017

Case 5-2018: A Man with Confusion after Stem-Cell Transplantation.

N Engl J Med 2018 06;378(26):2545

Massachusetts General Hospital, Boston, MA

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http://dx.doi.org/10.1056/NEJMc1806522DOI Listing
June 2018

Neuropathology Education Using Social Media.

J Neuropathol Exp Neurol 2018 06;77(6):454-460

Departments of Pathology and Laboratory Medicine, and Neurology, Warren Alpert Medical School of Brown University, Lifespan Academic Medical Center, Providence, Rhode Island.

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http://dx.doi.org/10.1093/jnen/nly025DOI Listing
June 2018

The role of proton beam therapy in central neurocytoma: A single-institution experience.

Pract Radiat Oncol 2018 Sep - Oct;8(5):e305-e311. Epub 2018 Feb 16.

Harvard Medical School, Boston, Massachusetts; Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18798500183006
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http://dx.doi.org/10.1016/j.prro.2018.02.005DOI Listing
November 2018

Thyroidosis Mistaken for Thyroid Cancer.

JAMA Otolaryngol Head Neck Surg 2018 Jun;144(6):540-541

Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://archotol.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaoto.2018.0066DOI Listing
June 2018

Practical Implications of the Updated WHO Classification of Brain Tumors.

Semin Neurol 2018 02 16;38(1):11-18. Epub 2018 Mar 16.

Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1055/s-0038-1641162DOI Listing
February 2018

Case 5-2018: A 63-Year-Old Man with Confusion after Stem-Cell Transplantation.

N Engl J Med 2018 Feb;378(7):659-669

From the Departments of Medicine (A.R.E.-J., J.B.E.K.), Radiology (P.W.S.), and Pathology (M.M.-L.), Massachusetts General Hospital, and the Departments of Medicine (A.R.E.-J., J.B.E.K.), Radiology (P.W.S.), and Pathology (M.M.-L.), Harvard Medical School - both in Boston.

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http://www.nejm.org/doi/10.1056/NEJMcpc1707556
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http://dx.doi.org/10.1056/NEJMcpc1707556DOI Listing
February 2018

Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy.

Ann Neurol 2018 02 15;83(2):311-327. Epub 2018 Feb 15.

Department of Neurology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1002/ana.25149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821556PMC
February 2018

19-Year-Old Male with Headaches and a Possible Seizure.

Brain Pathol 2017 07;27(4):557-558

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/bpa.12529DOI Listing
July 2017

Detection of EGFRvIII in Glioblastoma via Perfusion Magnetic Resonance Imaging Signature Consistent with Deep Peritumoral Infiltration: The -Index.

Clin Cancer Res 2017 Aug 20;23(16):4724-4734. Epub 2017 Apr 20.

Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559313PMC
August 2017

Intraoperative Near-Infrared Optical Imaging Can Localize Gadolinium-Enhancing Gliomas During Surgery.

Neurosurgery 2016 Dec;79(6):856-871

*Department of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; ‡Department of Pathology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; §Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; ¶Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1227/NEU.0000000000001450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123788PMC
December 2016

Prevalence of clinically silent corticotroph macroadenomas.

Clin Endocrinol (Oxf) 2016 Dec 27;85(6):874-880. Epub 2016 Jul 27.

Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/cen.13146DOI Listing
December 2016

Synovial-type giant cell tumors of the axial spine.

J Neurosurg Sci 2017 02 11;61(1):106-109. Epub 2016 Feb 11.

Department of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA -

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http://dx.doi.org/10.23736/S0390-5616.16.03236-7DOI Listing
February 2017

Imaging Surrogates of Infiltration Obtained Via Multiparametric Imaging Pattern Analysis Predict Subsequent Location of Recurrence of Glioblastoma.

Neurosurgery 2016 Apr;78(4):572-80

Departments of ‡Radiology, §Neurosurgery, ¶Pathology and Laboratory Medicine, and ‖Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania; #Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Texas; **Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1227/NEU.0000000000001202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853918PMC
April 2016

Lateral Transorbital Endoscopic Access to the Hippocampus, Amygdala, and Entorhinal Cortex: Initial Clinical Experience.

ORL J Otorhinolaryngol Relat Spec 2015 30;77(6):321-32. Epub 2015 Sep 30.

Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa., USA.

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https://www.karger.com/Article/FullText/438762
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http://dx.doi.org/10.1159/000438762DOI Listing
September 2016

Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques.

Neuro Oncol 2016 Mar 16;18(3):417-25. Epub 2015 Jul 16.

Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania (L.M., J.M.P., M.A., L.R., N.D., D.M.O.); Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania (H.A., X.D., R.L.W., M.B., C.D.); Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania (H.A., X.D., V.P., M.B., C.D.); Department of Biomedical Informatics, Northwestern University Feinberg School of Medicine, Chicago, Illinois (Y.B., S.P., R.V.D.); Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, Texas (G.B.); Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (M.M.-L., D.M.O.).

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http://dx.doi.org/10.1093/neuonc/nov127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767233PMC
March 2016

Factors associated with increased survival after surgical resection of glioblastoma in octogenarians.

PLoS One 2015 15;10(5):e0127202. Epub 2015 May 15.

Department of Neurosurgery, Hospital of the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127202PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433248PMC
April 2016

Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma.

Mol Cancer Res 2015 Aug 1;13(8):1227-37. Epub 2015 May 1.

Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania. Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0183-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679183PMC
August 2015

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas.

Nat Genet 2014 Feb 12;46(2):161-5. Epub 2014 Jan 12.

1] Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Pathology, Boston Children's Hospital, Boston, Massachusetts, USA. [3] Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA. [4] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [5].

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http://dx.doi.org/10.1038/ng.2868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982316PMC
February 2014

Mega-epsilon waves on 12-lead ECG--just another case of arrhythmogenic right ventricular dysplasia/cardiomyopathy?

J Electrocardiol 2013 Nov-Dec;46(6):524-7. Epub 2013 Sep 7.

Lankenua Medical Centre, Wynnewood, PA, USA.

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http://dx.doi.org/10.1016/j.jelectrocard.2013.08.007DOI Listing
July 2014

The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas.

Mod Pathol 2013 Nov 14;26(11):1425-32. Epub 2013 Jun 14.

1] Division of Neuropathology, Department of Pathology, University of California, San Francisco, San Francisco, CA, USA [2] Division of Surgical Pathology, Department of Pathology, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/modpathol.2013.90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054791PMC
November 2013

Dry Beriberi and Wernicke's encephalopathy following gastric lap band surgery.

J Clin Neurosci 2012 Jul 22;19(7):1050-2. Epub 2012 Apr 22.

Department of Neurology, University of Pennsylvania Medical Center, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.jocn.2011.11.006DOI Listing
July 2012

TDP-43 pathology in a case of hereditary spastic paraplegia with a NIPA1/SPG6 mutation.

Acta Neuropathol 2012 Aug;124(2):285-91

Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research (CNDR), University of Pennsylvania Health System, 3400 Spruce St, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s00401-012-0947-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361549PMC
August 2012

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

Authors:
Vivianna M Van Deerlin Patrick M A Sleiman Maria Martinez-Lage Alice Chen-Plotkin Li-San Wang Neill R Graff-Radford Dennis W Dickson Rosa Rademakers Bradley F Boeve Murray Grossman Steven E Arnold David M A Mann Stuart M Pickering-Brown Harro Seelaar Peter Heutink John C van Swieten Jill R Murrell Bernardino Ghetti Salvatore Spina Jordan Grafman John Hodges Maria Grazia Spillantini Sid Gilman Andrew P Lieberman Jeffrey A Kaye Randall L Woltjer Eileen H Bigio Marsel Mesulam Safa Al-Sarraj Claire Troakes Roger N Rosenberg Charles L White Isidro Ferrer Albert Lladó Manuela Neumann Hans A Kretzschmar Christine Marie Hulette Kathleen A Welsh-Bohmer Bruce L Miller Ainhoa Alzualde Adolfo Lopez de Munain Ann C McKee Marla Gearing Allan I Levey James J Lah John Hardy Jonathan D Rohrer Tammaryn Lashley Ian R A Mackenzie Howard H Feldman Ronald L Hamilton Steven T Dekosky Julie van der Zee Samir Kumar-Singh Christine Van Broeckhoven Richard Mayeux Jean Paul G Vonsattel Juan C Troncoso Jillian J Kril John B J Kwok Glenda M Halliday Thomas D Bird Paul G Ince Pamela J Shaw Nigel J Cairns John C Morris Catriona Ann McLean Charles DeCarli William G Ellis Stefanie H Freeman Matthew P Frosch John H Growdon Daniel P Perl Mary Sano David A Bennett Julie A Schneider Thomas G Beach Eric M Reiman Bryan K Woodruff Jeffrey Cummings Harry V Vinters Carol A Miller Helena C Chui Irina Alafuzoff Päivi Hartikainen Danielle Seilhean Douglas Galasko Eliezer Masliah Carl W Cotman M Teresa Tuñón M Cristina Caballero Martínez David G Munoz Steven L Carroll Daniel Marson Peter F Riederer Nenad Bogdanovic Gerard D Schellenberg Hakon Hakonarson John Q Trojanowski Virginia M-Y Lee

Nat Genet 2010 Mar 14;42(3):234-9. Epub 2010 Feb 14.

[1] Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. [2] These authors contributed equally to this work.

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http://dx.doi.org/10.1038/ng.536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828525PMC
March 2010

Brain progranulin expression in GRN-associated frontotemporal lobar degeneration.

Acta Neuropathol 2010 Jan 2;119(1):111-22. Epub 2009 Aug 2.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s00401-009-0576-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104467PMC
January 2010

Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases.

J Neurol 2009 Aug 7;256(8):1205-14. Epub 2009 Mar 7.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, HUP, Maloney 3rd Floor, 3600 Spruce Street, Philadelphia, PA 19104-4283, USA.

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http://dx.doi.org/10.1007/s00415-009-5069-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790321PMC
August 2009

Amyotrophic lateral sclerosis-plus syndrome with TAR DNA-binding protein-43 pathology.

Arch Neurol 2009 Jan;66(1):121-4

Department of Neurology, University of Pennsylvania School of Medicine, 330 S 9th St, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1001/archneur.66.1.121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702763PMC
January 2009

Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis.

Arch Neurol 2008 May;65(5):636-41

Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Alzheimer's Disease Core Center, Institute on Aging, Philadelphia, USA.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/arc
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http://dx.doi.org/10.1001/archneur.65.5.636DOI Listing
May 2008

Clinical and pathological heterogeneity of neuronal intermediate filament inclusion disease.

Arch Neurol 2008 Feb;65(2):272-5

Service of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, Barcelona, Spain.

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http://dx.doi.org/10.1001/archneurol.2007.37DOI Listing
February 2008

A novel antiganglioside specificity against terminal NeuNAc(alfa 2-3)Gal in acute bulbar palsy.

J Neuroimmunol 2006 Jul 16;176(1-2):219-22. Epub 2006 May 16.

Department of Neurology, Hospital de la Sta. Creu i St. Pau and Institut de Recerca HSCSP, Universitat Autònoma de Barcelona, Barcelona, Sant Antoni Maria Claret 167 08025, Spain.

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http://dx.doi.org/10.1016/j.jneuroim.2006.04.001DOI Listing
July 2006

Does thrombolysis benefit patients with lacunar syndrome?

Eur Neurol 2006 10;55(2):70-3. Epub 2006 Mar 10.

Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Spain.

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http://dx.doi.org/10.1159/000091982DOI Listing
October 2006