Publications by authors named "Maria Martínez de Lagrán"

18Publications

Behavioral Phenotyping for Down Syndrome in Mice.

Curr Protoc Mouse Biol 2020 Sep;10(3):e79

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.

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http://dx.doi.org/10.1002/cpmo.79DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552827PMC
September 2020

Down Syndrome Is a Metabolic Disease: Altered Insulin Signaling Mediates Peripheral and Brain Dysfunctions.

Front Neurosci 2020 8;14:670. Epub 2020 Jul 8.

Department of Biochemical Sciences "A. Rossi-Fanelli", Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.3389/fnins.2020.00670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360727PMC
July 2020

Ethanol-Induced Changes in Brain of Transgenic Mice Overexpressing DYRK1A.

Mol Neurobiol 2020 Jul 5;57(7):3195-3205. Epub 2020 Jun 5.

Université de Paris, BFA, UMR 8251, CNRS, F-75013, Paris, France.

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http://dx.doi.org/10.1007/s12035-020-01967-6DOI Listing
July 2020

Mapping behavioral landscapes in Down syndrome animal models.

Prog Brain Res 2020 30;251:145-179. Epub 2020 Jan 30.

Systems Biology Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/bs.pbr.2020.01.005DOI Listing
January 2020

Infralimbic Neurotrophin-3 Infusion Rescues Fear Extinction Impairment in a Mouse Model of Pathological Fear.

Neuropsychopharmacology 2017 01 18;42(2):462-472. Epub 2016 Aug 18.

Systems Biology Programme, Centre for Genomic Regulation (CRG)/Barcelona Biomedical Research Park, Barcelona, Spain.

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http://dx.doi.org/10.1038/npp.2016.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399232PMC
January 2017

Overexpression of Dyrk1A, a Down Syndrome Candidate, Decreases Excitability and Impairs Gamma Oscillations in the Prefrontal Cortex.

J Neurosci 2016 Mar;36(13):3648-59

Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, 08003 Barcelona, Spain, Pompeu Fabra University (UPF), 08003 Barcelona, Spain, Centre for Biomedical Research on Rare Diseases (CIBERER) 08003 Barcelona, Spain,

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http://dx.doi.org/10.1523/JNEUROSCI.2517-15.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601739PMC
March 2016

Erbb4 deletion from fast-spiking interneurons causes schizophrenia-like phenotypes.

Neuron 2013 Sep;79(6):1152-68

Instituto de Neurociencias, Consejo Superior de Investigaciones Científicas and Universidad Miguel Hernández, Sant Joan d'Alacant 03550, Spain.

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http://dx.doi.org/10.1016/j.neuron.2013.07.010DOI Listing
September 2013

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.

Mol Nutr Food Res 2014 Feb 14;58(2):278-88. Epub 2013 Sep 14.

Human Pharmacology and Clinical Neurosciences Research Group-Neurosciences Program, IMIM-Hospital del Mar Research Institute, Barcelona, Spain; Cardiovascular Risk and Nutrition Research Group-Inflammatory and Cardiovascular Disorders Program, IMIM-Hospital del Mar Research Institute, and CIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), Barcelona, Spain; University Pompeu Fabra, CEXS-UPF, Barcelona, Spain.

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http://dx.doi.org/10.1002/mnfr.201300325DOI Listing
February 2014

Environmental enrichment rescues DYRK1A activity and hippocampal adult neurogenesis in TgDyrk1A.

Neurobiol Dis 2013 Dec 20;60:18-31. Epub 2013 Aug 20.

Systems Biology Program, Centre for Genomic Regulation (CRG), Dr. Aiguader 88, E-08003 Barcelona, Spain; Universitat Pompeu Fabra (UPF), Dr. Aiguader 88, E-08003 Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Dr. Aiguader 88, E-08003 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.nbd.2013.08.008DOI Listing
December 2013

Functional implications of hippocampal adult neurogenesis in intellectual disabilities.

Amino Acids 2013 Jul 20;45(1):113-31. Epub 2013 Apr 20.

Systems Biology Program, Centre for Genomic Regulation (CRG), Dr. Aiguader 88, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1007/s00726-013-1489-xDOI Listing
July 2013

Reduced Mid1 Expression and Delayed Neuromotor Development in daDREAM Transgenic Mice.

Front Mol Neurosci 2012 3;5:58. Epub 2012 May 3.

Genomic Regulation Center, Parc de Recerca Biomèdica de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Raras Barcelona, Spain.

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http://dx.doi.org/10.3389/fnmol.2012.00058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342529PMC
October 2012

Insights from mouse models to understand neurodegeneration in Down syndrome.

CNS Neurol Disord Drug Targets 2010 Aug;9(4):429-38

Centre de Regulació Genòmica, UPF, Parc de Recerca Biomèdica de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Raras, Spain.

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http://dx.doi.org/10.2174/187152710791556159DOI Listing
August 2010

Age-associated motor and visuo-spatial learning phenotype in Dyrk1A heterozygous mutant mice.

Neurobiol Dis 2009 Nov 4;36(2):312-9. Epub 2009 Aug 4.

Genes and Disease Program, Center for Genomic Regulation (CRG), Pompeu Fabra University, Barcelona Biomedical Research Park (PRBB) and CIBER de Enfermedades Raras (CIBERER), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.nbd.2009.07.027DOI Listing
November 2009

Pitfalls and hopes in Down syndrome therapeutic approaches: in the search for evidence-based treatments.

Behav Genet 2006 May 7;36(3):454-68. Epub 2006 Mar 7.

Genes and Disease Program, Genomic Regulation Center, (CRG-UPF), Barcelona Biomedical Research Park, Spain.

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http://dx.doi.org/10.1007/s10519-006-9050-2DOI Listing
May 2006