Publications by authors named "Maria Luisa Mangoni"

91Publications

Antipseudomonal and Immunomodulatory Properties of Esc Peptides: Promising Features for Treatment of Chronic Infectious Diseases and Inflammation.

Authors:
Floriana Cappiello Veronica Carnicelli Bruno Casciaro Maria Luisa Mangoni

Int J Mol Sci 2021 Jan 8;22(2). Epub 2021 Jan 8.

Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy.

View Article and Find Full Text PDF
January 2021

The Antimicrobial Peptide Temporin G: Anti-Biofilm, Anti-Persister Activities, and Potentiator Effect of Tobramycin Efficacy Against .

Authors:
Bruno Casciaro Maria Rosa Loffredo Floriana Cappiello Guendalina Fabiano Luisa Torrini Maria Luisa Mangoni

Int J Mol Sci 2020 Dec 10;21(24). Epub 2020 Dec 10.

Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

View Article and Find Full Text PDF
December 2020

Development of Antimicrobial Peptides from Amphibians.

Authors:
Maria Luisa Mangoni Bruno Casciaro

Antibiotics (Basel) 2020 Nov 4;9(11). Epub 2020 Nov 4.

Center For Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy.

View Article and Find Full Text PDF
November 2020

Novel temporin L antimicrobial peptides: promoting self-assembling by lipidic tags to tackle superbugs.

Authors:
Rosa Bellavita Annarita Falanga Elisabetta Buommino Francesco Merlino Bruno Casciaro Floriana Cappiello Maria Luisa Mangoni Ettore Novellino Maria Rosaria Catania Rossella Paolillo Paolo Grieco Stefania Galdieroa

J Enzyme Inhib Med Chem 2020 Dec;35(1):1751-1764

Department of Pharmacy, University of Naples "Federico II", Naples, Italy.

View Article and Find Full Text PDF
December 2020

-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors.

Authors:
Deborah Quaglio Maria Luisa Mangoni Roberta Stefanelli Silvia Corradi Bruno Casciaro Valeria Vergine Federica Lucantoni Luca Cavinato Silvia Cammarone Maria Rosa Loffredo Floriana Cappiello Andrea Calcaterra Silvia Erazo Francesca Ghirga Mattia Mori Francesco Imperi Fiorentina Ascenzioni Bruno Botta

J Org Chem 2020 Aug 10;85(16):10891-10901. Epub 2020 Aug 10.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

View Article and Find Full Text PDF
August 2020

Naturally-Occurring Alkaloids of Plant Origin as Potential Antimicrobials against Antibiotic-Resistant Infections.

Authors:
Bruno Casciaro Laura Mangiardi Floriana Cappiello Isabella Romeo Maria Rosa Loffredo Antonia Iazzetti Andrea Calcaterra Antonella Goggiamani Francesca Ghirga Maria Luisa Mangoni Bruno Botta Deborah Quaglio

Molecules 2020 Aug 9;25(16). Epub 2020 Aug 9.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

View Article and Find Full Text PDF
August 2020

Frog Skin-Derived Peptides Against Correlation between Antibacterial and Cytotoxic Activities.

Authors:
Bruno Casciaro Maria Rosa Loffredo Floriana Cappiello Walter Verrusio Vito Domenico Corleto Maria Luisa Mangoni

Antibiotics (Basel) 2020 Jul 26;9(8). Epub 2020 Jul 26.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

View Article and Find Full Text PDF
July 2020

The Revaluation of Plant-Derived Terpenes to Fight Antibiotic-Resistant Infections.

Authors:
Floriana Cappiello Maria Rosa Loffredo Cristina Del Plato Silvia Cammarone Bruno Casciaro Deborah Quaglio Maria Luisa Mangoni Bruno Botta Francesca Ghirga

Antibiotics (Basel) 2020 Jun 13;9(6). Epub 2020 Jun 13.

Center For Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy.

View Article and Find Full Text PDF
June 2020

Structural Elucidation and Antimicrobial Characterization of Novel Diterpenoids from var. .

Authors:
Deborah Quaglio Silvia Corradi Silvia Erazo Valeria Vergine Simone Berardozzi Fabio Sciubba Floriana Cappiello Maria Elisa Crestoni Fiorentina Ascenzioni Francesco Imperi Franco Delle Monache Mattia Mori Maria Rosa Loffredo Francesca Ghirga Bruno Casciaro Bruno Botta Maria Luisa Mangoni

ACS Med Chem Lett 2020 May 30;11(5):760-765. Epub 2020 Jan 30.

Department of Biochemical Sciences, Laboratory Affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, P.le Aldo Moro 5 00185, Rome, Italy.

View Article and Find Full Text PDF
May 2020

Nanotechnologies to Improve the Pharmacological Profile of Therapeutic Peptides.

Authors:
Bruno Casciaro Maria Luisa Mangoni

Curr Protein Pept Sci 2020 ;21(4):332-333

Department of Biochemical Sciences "A. Rossi Fanelli" Sapienza University of Rome Piazzale Aldo Moro, 5 00185 Roma, Italy.

View Article and Find Full Text PDF
January 2021

Antimicrobial Peptides and their Multiple Effects at Sub-Inhibitory Concentrations.

Authors:
Bruno Casciaro Floriana Cappiello Walter Verrusio Mauro Cacciafesta Maria Luisa Mangoni

Curr Top Med Chem 2020 ;20(14):1264-1273

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, P.le Aldo Moro 5, Rome 00185, Italy.

View Article and Find Full Text PDF
January 2021

Bronchial epithelium repair by Esculentin-1a-derived antimicrobial peptides: involvement of metalloproteinase-9 and interleukin-8, and evaluation of peptides' immunogenicity.

Authors:
Floriana Cappiello Danilo Ranieri Veronica Carnicelli Bruno Casciaro Han-Tang Chen Loretta Ferrera Y Peter Di Maria Luisa Mangoni

Sci Rep 2019 12 12;9(1):18988. Epub 2019 Dec 12.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.

View Article and Find Full Text PDF
December 2019

Inorganic Gold and Polymeric Poly(Lactide-co-glycolide) Nanoparticles as Novel Strategies to Ameliorate the Biological Properties of Antimicrobial Peptides.

Authors:
Bruno Casciaro Francesca Ghirga Deborah Quaglio Maria Luisa Mangoni

Curr Protein Pept Sci 2020 ;21(4):429-438

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.

View Article and Find Full Text PDF
January 2021

Aggregation determines the selectivity of membrane-active anticancer and antimicrobial peptides: The case of killerFLIP.

Authors:
Zahra Vaezi Annalisa Bortolotti Vincenzo Luca Giulia Perilli Maria Luisa Mangoni Roya Khosravi-Far Sara Bobone Lorenzo Stella

Biochim Biophys Acta Biomembr 2020 02 31;1862(2):183107. Epub 2019 Oct 31.

Department of Chemical Science and Technologies, University of Rome Tor Vergata, 00133 Rome, Italy. Electronic address:

View Article and Find Full Text PDF
February 2020

Nigritanine as a New Potential Antimicrobial Alkaloid for the Treatment of -Induced Infections.

Authors:
Bruno Casciaro Andrea Calcaterra Floriana Cappiello Mattia Mori Maria Rosa Loffredo Francesca Ghirga Maria Luisa Mangoni Bruno Botta Deborah Quaglio

Toxins (Basel) 2019 09 1;11(9). Epub 2019 Sep 1.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University of Rome, P.le Aldo Moro 5, Rome 00185, Italy.

View Article and Find Full Text PDF
September 2019

The Potential of Frog Skin Peptides for Anti-Infective Therapies: The Case of Esculentin-1a(1-21)NH2.

Authors:
Bruno Casciaro Floriana Cappiello Maria Rosa Loffredo Francesca Ghirga Maria Luisa Mangoni

Curr Med Chem 2020 ;27(9):1405-1419

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.

View Article and Find Full Text PDF
May 2020

Inhibition of Pseudomonas aeruginosa biofilm formation and expression of virulence genes by selective epimerization in the peptide Esculentin-1a(1-21)NH.

Authors:
Bruno Casciaro Qiao Lin Sergii Afonin Maria Rosa Loffredo Valeria de Turris Volker Middel Anne S Ulrich YuanPu Peter Di Maria Luisa Mangoni

FEBS J 2019 10 13;286(19):3874-3891. Epub 2019 Jun 13.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, Italy.

View Article and Find Full Text PDF
October 2019

The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L.

Authors:
Elisabetta Buommino Alfonso Carotenuto Ignazio Antignano Rosa Bellavita Bruno Casciaro Maria Rosa Loffredo Francesco Merlino Ettore Novellino Maria Luisa Mangoni Francesca Paola Nocera Diego Brancaccio Pasqualina Punzi Daniela Roversi Raffaele Ingenito Elisabetta Bianchi Paolo Grieco

ChemMedChem 2019 07 3;14(13):1283-1290. Epub 2019 Jun 3.

Department of Pharmacy, University of Naples "Federico II", Naples, 80131, Italy.

View Article and Find Full Text PDF
July 2019

Poly(lactide- co-glycolide) Nanoparticles for Prolonged Therapeutic Efficacy of Esculentin-1a-Derived Antimicrobial Peptides against Pseudomonas aeruginosa Lung Infection: in Vitro and in Vivo Studies.

Authors:
Bruno Casciaro Ivana d'Angelo Xiaoping Zhang Maria Rosa Loffredo Gemma Conte Floriana Cappiello Fabiana Quaglia Yuan-Pu Peter Di Francesca Ungaro Maria Luisa Mangoni

Biomacromolecules 2019 05 23;20(5):1876-1888. Epub 2019 Apr 23.

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences "A. Rossi Fanelli" , Sapienza University of Rome , via degli Apuli, 9 , 00185 Rome , Italy.

View Article and Find Full Text PDF
May 2019

Esculentin-1a Derived Antipseudomonal Peptides: Limited Induction of Resistance and Synergy with Aztreonam.

Authors:
Bruno Casciaro Maria Rosa Loffredo Vincenzo Luca Walter Verrusio Mauro Cacciafesta Maria Luisa Mangoni

Protein Pept Lett 2018 ;25(12):1155-1162

Laboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, via degli Apuli, 9, 00185, Rome, Italy.

View Article and Find Full Text PDF
February 2019