Publications

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
Neuron 2017 Mar;93(5):1015-1034
Department of Medical Genetics, Cambridge Institute for Medical Research, Cambridge Biomedical Campus, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK. Electronic address:

CCT complex restricts neuropathogenic protein aggregation via autophagy.
Nat Commun 2016 Dec 8;7:13821. Epub 2016 Dec 8.
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.


PICALM modulates autophagy activity and tau accumulation.
Nat Commun 2014 Sep 22;5:4998. Epub 2014 Sep 22.
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.

Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy.
Nat Commun 2014 May 13;5:3828. Epub 2014 May 13.
Department of Medical Genetics, Cambridge Institute for Medical Research, Cambridge Biomedical Campus, University of Cambridge, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK.

Phosphoproteomic analysis of protein kinase C signaling in Saccharomyces cerevisiae reveals Slt2 mitogen-activated protein kinase (MAPK)-dependent phosphorylation of eisosome core components.
Mol Cell Proteomics 2013 Mar 9;12(3):557-74. Epub 2012 Dec 9.
Departamento de Microbiología II, Facultad de Farmacia, Universidad Complutense de Madrid and Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Plaza de Ramón y Cajal s/n, Madrid, Spain.


Mammalian macroautophagy at a glance.
J Cell Sci 2009 Jun;122(Pt 11):1707-11
Department of Medical Genetics, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

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