Publications by authors named "Maria Insenser"

35Publications

Postprandial responses of circulating energy homeostasis mediators to single macronutrient challenges: influence of obesity and sex hormones.

Food Funct 2021 Jan 14. Epub 2021 Jan 14.

Diabetes, Obesity and Human Reproduction Research Group, Department of Endocrinology & Nutrition, Hospital Universitario Ramón y Cajal & Universidad de Alcalá & Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS & Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Madrid, Spain.

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January 2021

Acute-phase glycoprotein profile responses to different oral macronutrient challenges: Influence of sex, functional hyperandrogenism and obesity.

Clin Nutr 2020 Aug 14. Epub 2020 Aug 14.

Diabetes, Obesity and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal & Universidad de Alcalá & Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS & Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), E-28034, Madrid, Spain. Electronic address:

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August 2020

Changes in Soluble TWEAK Concentrations, but Not Those in Amyloid-β(1-40), Are Associated with a Decrease in Carotid Intima-Media Thickness after Bariatric Surgery in Obese Women.

Obes Facts 2020 8;13(3):321-330. Epub 2020 May 8.

Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal and Universidad de Alcalá and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain,

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May 2020

2D Diffusion-Ordered H-NMR Spectroscopy Lipidomic Profiling after Oral Single Macronutrient Loads: Influence of Obesity, Sex, and Female Androgen Excess.

Mol Nutr Food Res 2020 05 13;64(9):e1900928. Epub 2020 Apr 13.

Diabetes, Obesity and Human Reproduction Research Group, Department of Endocrinology & Nutrition, Hospital Universitario Ramón y Cajal & Universidad de Alcalá & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) & Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, E-28034, Spain.

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May 2020

TLR2 and TLR4 Surface and Gene Expression in White Blood Cells after Fasting and Oral Glucose, Lipid and Protein Challenges: Influence of Obesity and Sex Hormones.

Biomolecules 2020 01 9;10(1). Epub 2020 Jan 9.

Diabetes, Obesity and Human Reproduction Research Group, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal &Universidad de Alcalá &Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) & Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), 28034 Madrid, Spain.

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January 2020

Metabolic Cytokines at Fasting and During Macronutrient Challenges: Influence of Obesity, Female Androgen Excess and Sex.

Nutrients 2019 Oct 24;11(11). Epub 2019 Oct 24.

Diabetes, Obesity and Human Reproduction Research Group, Department of Endocrinology & Nutrition, Hospital Universitario Ramón y Cajal & Universidad de Alcalá & Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS & Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Madrid 28034, Spain.

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October 2019

Glycoprotein A and B Height-to-Width Ratios as Obesity-Independent Novel Biomarkers of Low-Grade Chronic Inflammation in Women with Polycystic Ovary Syndrome (PCOS).

J Proteome Res 2019 11 27;18(11):4038-4045. Epub 2019 Sep 27.

Diabetes, Obesity and Human Reproduction Research Group , Hospital Universitario Ramón y Cajal & Universidad de Alcalá & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) , 28034 Madrid , Spain.

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November 2019

Androgen Excess in Women: Proteomic and Metabolomic Approaches.

Front Horm Res 2019 9;53:162-176. Epub 2019 Sep 9.

Diabetes Obesity and Human Reproduction Research Group, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal and Universidad de Alcalá, Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain,

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March 2020

Postprandial inflammatory responses after oral glucose, lipid and protein challenges: Influence of obesity, sex and polycystic ovary syndrome.

Clin Nutr 2020 Mar 1;39(3):876-885. Epub 2019 Apr 1.

Diabetes, Obesity and Human Reproduction Research Group, Department of Endocrinology & Nutrition, Hospital Universitario Ramón y Cajal, Universidad de Alcalá & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain. Electronic address:

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March 2020

Gut Microbiota and the Polycystic Ovary Syndrome: Influence of Sex, Sex Hormones, and Obesity.

J Clin Endocrinol Metab 2018 07;103(7):2552-2562

Diabetes Obesity and Human Reproduction Research Group, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal & Universidad de Alcalá, Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.

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July 2018

Non-targeted profiling of circulating microRNAs in women with polycystic ovary syndrome (PCOS): effects of obesity and sex hormones.

Metabolism 2018 09 2;86:49-60. Epub 2018 Feb 2.

Diabetes, Obesity and Human Reproduction Research Group, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain. Electronic address:

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September 2018

Circulating adiponectin increases in obese women after sleeve gastrectomy or gastric bypass driving beneficial metabolic changes but with no relationship with carotid intima-media thickness.

Clin Nutr 2018 12 12;37(6 Pt A):2102-2106. Epub 2017 Oct 12.

Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain; Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Madrid, Spain. Electronic address:

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December 2018

Plasma thiobarbituric acid reactive substances (TBARS) in young adults: Obesity increases fasting levels only in men whereas glucose ingestion, and not protein or lipid intake, increases postprandial concentrations regardless of sex and obesity.

Mol Nutr Food Res 2017 11 29;61(11). Epub 2017 Aug 29.

Diabetes, Obesity and Human Reproduction Research Group, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Madrid, Spain.

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November 2017

A nontargeted study of muscle proteome in severely obese women with androgen excess compared with severely obese men and nonhyperandrogenic women.

Eur J Endocrinol 2016 Mar 15;174(3):389-98. Epub 2015 Dec 15.

DiabetesObesity and Human Reproduction Research Group, Department of Endocrinology and Nutrition, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Carretera de Colmenar km 9,1, E-28034 Madrid, Spain

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March 2016

Allelic Mutations of KITLG, Encoding KIT Ligand, Cause Asymmetric and Unilateral Hearing Loss and Waardenburg Syndrome Type 2.

Am J Hum Genet 2015 Nov 29;97(5):647-60. Epub 2015 Oct 29.

Hearing & Genes Division, Department of Otorhinolaryngology, Radboud University Medical Center, Nijmegen 6525GA, the Netherlands; The Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen 6525GA, the Netherlands; Department of Human Genetics, Radboud University Medical Center, Nijmegen 6525GA, the Netherlands. Electronic address:

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November 2015

Identification of reduced circulating haptoglobin concentration as a biomarker of the severity of pulmonary embolism: a nontargeted proteomic study.

PLoS One 2014 30;9(6):e100902. Epub 2014 Jun 30.

Respiratory Department, Pulmonary Embolism Research Group, Hospital Universitario Ramón y Cajal & Universidad de Alcalá & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.

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February 2015

Proteomic analysis of adipose tissue: informing diabetes research.

Expert Rev Proteomics 2014 Aug 31;11(4):491-502. Epub 2014 Mar 31.

Department of Endocrinology and Nutrition, Diabetes, Obesity and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal and Universidad de Alcalá and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) and Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), E-28034 Madrid, Spain.

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August 2014

Metabolomics in polycystic ovary syndrome.

Clin Chim Acta 2014 Feb 22;429:181-8. Epub 2013 Dec 22.

Diabetes, Obesity and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, E-28034 Madrid, Spain; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), E-28034 Madrid, Spain; Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), E-28034 Madrid, Spain. Electronic address:

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February 2014

Proteomics and polycystic ovary syndrome.

Expert Rev Proteomics 2013 Oct 3;10(5):435-47. Epub 2013 Oct 3.

Diabetes, Obesity and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal & Universidad de Alcalá & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) & Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), E-28034 Madrid, Spain.

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October 2013

Effects of polycystic ovary syndrome (PCOS), sex hormones, and obesity on circulating miRNA-21, miRNA-27b, miRNA-103, and miRNA-155 expression.

J Clin Endocrinol Metab 2013 Nov 13;98(11):E1835-44. Epub 2013 Sep 13.

or Héctor F. Escobar-Morreale, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Carretera de Colmenar km 9'1, E-28034 Madrid, Spain.

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November 2013

Proteomic analysis of visceral adipose tissue in pre-obese patients with type 2 diabetes.

Mol Cell Endocrinol 2013 Aug 18;376(1-2):99-106. Epub 2013 Jun 18.

Diabetes, Obesity and Human Reproduction Group, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Madrid, Spain.

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August 2013

Sexual dimorphism in adipose tissue function as evidenced by circulating adipokine concentrations in the fasting state and after an oral glucose challenge.

Hum Reprod 2013 Jul 4;28(7):1908-18. Epub 2013 Apr 4.

Diabetes, Obesity and Human Reproduction Research Group, Universidad de Alcalá and Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS and Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain.

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July 2013

Mediators of low-grade chronic inflammation in polycystic ovary syndrome (PCOS).

Curr Pharm Des 2013 ;19(32):5775-91

Diabetes, Obesity and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal & Universidad de Alcalá & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS) & Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), E-28034 Madrid, Spain.

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March 2014

Proteomic and metabolomic approaches to the study of polycystic ovary syndrome.

Mol Cell Endocrinol 2013 May 17;370(1-2):65-77. Epub 2013 Feb 17.

Diabetes, Obesity and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal & Universidad de Alcalá, E-28034 Madrid, Spain.

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May 2013

A nontargeted proteomic study of the influence of androgen excess on human visceral and subcutaneous adipose tissue proteomes.

J Clin Endocrinol Metab 2013 Mar 24;98(3):E576-85. Epub 2013 Jan 24.

Diabetes, Obesity, and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal and Universidad de Alcalá & Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.

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March 2013

Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis.

Hum Reprod Update 2013 May-Jun;19(3):268-88. Epub 2013 Jan 9.

Diabetes, Obesity and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal, Madrid, Spain.

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September 2013

A nontargeted proteomic approach to the study of visceral and subcutaneous adipose tissue in human obesity.

Mol Cell Endocrinol 2012 Nov 14;363(1-2):10-9. Epub 2012 Jul 14.

Diabetes, Obesity and Human Reproduction Group, Universidad de Alcalá & Hospital Universitario Ramón y Cajal & Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain.

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November 2012

Metabolic heterogeneity in polycystic ovary syndrome is determined by obesity: plasma metabolomic approach using GC-MS.

Clin Chem 2012 Jun 16;58(6):999-1009. Epub 2012 Mar 16.

Diabetes, Obesity and Human Reproduction Research Group, Hospital Universitario Ramón y Cajal & Universidad de Alcalá, Madrid, Spain.

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June 2012

Impact of the storage temperature on human plasma proteomic analysis: implications for the use of human plasma collections in research.

Proteomics Clin Appl 2010 Sep;4(8-9):739-44

Department of Endocrinology, Hospital Universitario Ramon y Cajal and Universidad de Alcala and Instituto Ramon y Cajal de Investigacion Sanitaria IRYCIS, Spain.

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September 2010

Proteomic analysis of plasma in the polycystic ovary syndrome identifies novel markers involved in iron metabolism, acute-phase response, and inflammation.

J Clin Endocrinol Metab 2010 Aug 19;95(8):3863-70. Epub 2010 May 19.

Department of Endocrinology, Hospital Universitario Ramón y Cajal and Universidad de Alcalá, Carretera de Colmenar Viejo Km 9,1 Madrid E-28034, Spain.

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August 2010

Gel and gel-free proteomics to identify Saccharomyces cerevisiae cell surface proteins.

J Proteomics 2010 Apr 20;73(6):1183-95. Epub 2010 Feb 20.

Departamento de Microbiología II, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza de Ramón y Cajal s/n, 28040 Madrid, Spain.

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April 2010

Proteomic analysis reveals metabolic changes during yeast to hypha transition in Yarrowia lipolytica.

J Mass Spectrom 2007 Nov;42(11):1453-62

Departamento de Microbiología y Genética, Instituto de Microbiología Bioquímica, CSIC/Universidad de Salamanca, 37007 Salamanca, Spain.

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November 2007

Proteomic analysis of detergent-resistant membranes from Candida albicans.

Proteomics 2006 Apr;6 Suppl 1:S74-81

Departamento de Microbiología II, Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain.

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April 2006