Maria Elena Bottazzi

Maria Elena Bottazzi

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Maria Elena Bottazzi

Publications by authors named "Maria Elena Bottazzi"

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Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection.

PLoS Negl Trop Dis 2020 Feb 13;14(2):e0008057. Epub 2020 Feb 13.

National School of Tropical Medicine, Departments of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0008057DOI Listing
February 2020

The Potential Economic Value of a Zika Vaccine for a Woman of Childbearing Age.

Am J Prev Med 2020 Jan 21. Epub 2020 Jan 21.

Public Health Informatics, Computational, and Operations Research (PHICOR), City University of New York, New York City, New York. Electronic address:

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http://dx.doi.org/10.1016/j.amepre.2019.10.023DOI Listing
January 2020

A method to probe protein structure from UV absorbance spectra.

Anal Biochem 2019 Dec 21;587:113450. Epub 2019 Sep 21.

National School of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, TX, 77030, USA; Texas Children's Hospital Center for Vaccine Development, Houston, TX, 77030, USA; Department of Biology, Baylor University, Waco, TX, 76706, USA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2019.113450DOI Listing
December 2019

Inspiring women scientists in Honduras.

EBioMedicine 2019 Nov 18;49:21. Epub 2019 Oct 18.

Associate Dean, National School of Tropical Medicine, Professor in Pediatric Tropical Medicine and Molecular Virology and Immunology and Co-director Texas Children's Hospital Center for Vaccine Development at Baylor College of Medicine, Houston Texas, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945274PMC
November 2019

Improved Biomarker and Imaging Analysis for Characterizing Progressive Cardiac Fibrosis in a Mouse Model of Chronic Chagasic Cardiomyopathy.

J Am Heart Assoc 2019 Nov 13;8(22):e013365. Epub 2019 Nov 13.

Department of Molecular Virology and Microbiology Baylor College of Medicine Houston TX.

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http://dx.doi.org/10.1161/JAHA.119.013365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915297PMC
November 2019

Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans.

PLoS Negl Trop Dis 2019 09 16;13(9):e0007730. Epub 2019 Sep 16.

Laboratory of Molecular Parasitology, Lindsley F Kimball Research Institute, New York Blood Center, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0007730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762197PMC
September 2019

Establishing Preferred Product Characterization for the Evaluation of RNA Vaccine Antigens.

Vaccines (Basel) 2019 Sep 27;7(4). Epub 2019 Sep 27.

Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, One Baylor Plaza, BCM113 Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/vaccines7040131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963847PMC
September 2019

"Running the Gauntlet": Formidable challenges in advancing neglected tropical diseases vaccines from development through licensure, and a "Call to Action".

Hum Vaccin Immunother 2019 10;15(10):2235-2242. Epub 2019 Jul 10.

Texas Children's Hospital Center for Vaccine Development, Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine , Houston , TX , USA.

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http://dx.doi.org/10.1080/21645515.2019.1629254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816440PMC
July 2019

Economic value of a therapeutic Chagas vaccine for indeterminate and Chagasic cardiomyopathy patients.

Vaccine 2019 Jun 16;37(28):3704-3714. Epub 2019 May 16.

Public Health Computational and Operational Research (PHICOR), Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA; Global Obesity Prevention Center (GOPC), Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X193065
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http://dx.doi.org/10.1016/j.vaccine.2019.05.028DOI Listing
June 2019

A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection.

PLoS Negl Trop Dis 2019 05 30;13(5):e0007413. Epub 2019 May 30.

Section of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0007413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542517PMC
May 2019

Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America.

Expert Rev Anti Infect Ther 2019 03 13;17(3):145-157. Epub 2019 Feb 13.

a ISGlobal, Hospital Clínic , Universitat de Barcelona , Barcelona , Spain.

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http://dx.doi.org/10.1080/14787210.2019.1577731DOI Listing
March 2019

Advancing the Development of a Human Schistosomiasis Vaccine.

Trends Parasitol 2019 02 16;35(2):104-108. Epub 2018 Nov 16.

Department of Microbiology, Immunology, and Tropical Medicine, George Washington University, Washington, DC, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S14714922183023
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http://dx.doi.org/10.1016/j.pt.2018.10.005DOI Listing
February 2019

China's shifting neglected parasitic infections in an era of economic reform, urbanization, disease control, and the Belt and Road Initiative.

PLoS Negl Trop Dis 2019 01 24;13(1):e0006946. Epub 2019 Jan 24.

Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0006946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345419PMC
January 2019

Covalent vaccination with Trypanosoma cruzi Tc24 induces catalytic antibody production.

Parasite Immunol 2018 Nov 24;40(11):e12585. Epub 2018 Sep 24.

Center for Infectious Disease, The University of Texas School of Public Health, Houston, Texas.

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http://doi.wiley.com/10.1111/pim.12585
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http://dx.doi.org/10.1111/pim.12585DOI Listing
November 2018

Lessons along the Critical Path: Developing Vaccines against Human Helminths.

Trends Parasitol 2018 09 28;34(9):747-758. Epub 2018 Jul 28.

Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington DC, USA; Texas Children's Hospital Center for Vaccine Development - a Product Development Partnership, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2018.07.005DOI Listing
September 2018

Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm.

PLoS Pathog 2018 08 28;14(8):e1007273. Epub 2018 Aug 28.

Texas Children's Hospital Center for Vaccine Development, Department of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1007273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130879PMC
August 2018

Characterization and Stability of Trypanosoma cruzi 24-C4 (Tc24-C4), a Candidate Antigen for a Therapeutic Vaccine Against Chagas Disease.

J Pharm Sci 2018 05 21;107(5):1468-1473. Epub 2017 Dec 21.

Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas 77030; Texas Children's Hospital Center for Vaccine Development, Houston, Texas 77030; Department of Biology, Baylor University, Waco, Texas 76706. Electronic address:

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http://dx.doi.org/10.1016/j.xphs.2017.12.014DOI Listing
May 2018

Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen.

Vaccine 2018 03 26;36(14):1853-1862. Epub 2018 Feb 26.

Texas Children's Hospital Center for Vaccine Development, USA; Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.vaccine.2018.02.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860679PMC
March 2018

Onchocerca volvulus: The Road from Basic Biology to a Vaccine.

Trends Parasitol 2018 01 22;34(1):64-79. Epub 2017 Sep 22.

Texas Children's Hospital Center for Vaccine Development, Department of Pediatrics, Section of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.pt.2017.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748257PMC
January 2018

Mutations to Cysteine Residues in the Trypanosoma cruzi B-Cell Superantigen Tc24 Diminish Susceptibility to IgM-Mediated Hydrolysis.

J Parasitol 2017 10 5;103(5):579-583. Epub 2017 Jun 5.

Baylor College of Medicine, National School of Tropical Medicine, Section of Tropical Medicine, Houston, Texas 77030.

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http://www.bioone.org/doi/10.1645/17-7
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http://dx.doi.org/10.1645/17-7DOI Listing
October 2017

Optimization of the Production Process and Characterization of the Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1), a SARS Vaccine Candidate.

J Pharm Sci 2017 08 26;106(8):1961-1970. Epub 2017 Apr 26.

Texas Children's Hospital Center for Vaccine Development, Houston, Texas 77030; Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas 77030; Department of Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas 77030; Department of Biology, Baylor University, Waco, Texas 76798; James A. Baker III Institute for Public Policy, Rice University, Houston, Texas 77005.

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https://linkinghub.elsevier.com/retrieve/pii/S00223549173027
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http://dx.doi.org/10.1016/j.xphs.2017.04.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612335PMC
August 2017

Identification, Characterization, and Structure of Tm16 from .

J Parasitol Res 2017 14;2017:4342789. Epub 2017 Aug 14.

National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital Center for Vaccine Development, Houston TX 77030, USA.

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http://dx.doi.org/10.1155/2017/4342789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573103PMC
August 2017

Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response.

PLoS Negl Trop Dis 2017 Jul 14;11(7):e0005769. Epub 2017 Jul 14.

Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America.

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https://dx.plos.org/10.1371/journal.pntd.0005769
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http://dx.doi.org/10.1371/journal.pntd.0005769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529013PMC
July 2017

A simple fluorescence-based assay for quantification of the Toll-Like Receptor agonist E6020 in vaccine formulations.

Vaccine 2017 03 9;35(10):1410-1416. Epub 2017 Feb 9.

Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX 77030, USA; Department of Biology, Baylor University, Waco, TX, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X173015
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http://dx.doi.org/10.1016/j.vaccine.2017.01.077DOI Listing
March 2017

Expression, purification, immunogenicity and protective efficacy of a recombinant nucleoside hydrolase from Leishmania donovani, a vaccine candidate for preventing cutaneous leishmaniasis.

Protein Expr Purif 2017 02 20;130:129-136. Epub 2016 Oct 20.

National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA; Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pep.2016.10.008DOI Listing
February 2017

Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine.

PLoS Negl Trop Dis 2017 02 13;11(2):e0005385. Epub 2017 Feb 13.

Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University, Washington DC, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0005385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325600PMC
February 2017

New Vaccines for the World's Poorest People.

Annu Rev Med 2016 3;67:405-17. Epub 2015 Sep 3.

Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas 77030; email:

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http://dx.doi.org/10.1146/annurev-med-051214-024241DOI Listing
October 2016

The Global Economic and Health Burden of Human Hookworm Infection.

PLoS Negl Trop Dis 2016 09 8;10(9):e0004922. Epub 2016 Sep 8.

Public Health Computational and Operational Research (PHICOR), Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0004922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015833PMC
September 2016

The hookworm Ancylostoma ceylanicum intestinal transcriptome provides a platform for selecting drug and vaccine candidates.

Parasit Vectors 2016 Sep 27;9(1):518. Epub 2016 Sep 27.

Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://parasitesandvectors.biomedcentral.com/articles/10.118
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039805PMC
http://dx.doi.org/10.1186/s13071-016-1795-8DOI Listing
September 2016

The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice.

PLoS Negl Trop Dis 2016 07 7;10(7):e0004797. Epub 2016 Jul 7.

Department of Microbiology and Immunology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0004797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936747PMC
July 2016

Status of vaccine research and development of vaccines for leishmaniasis.

Vaccine 2016 06 11;34(26):2992-2995. Epub 2016 Mar 11.

National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA; Sabin Vaccine Institute, Washington, DC, USA; Department of Biology, Baylor University, Waco, TX, USA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.12.071DOI Listing
June 2016

Status of vaccine research and development of vaccines for Chagas disease.

Vaccine 2016 06 26;34(26):2996-3000. Epub 2016 Mar 26.

National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA; Sabin Vaccine Institute, Washington, DC, USA; Department of Biology, Baylor University, Waco, TX, USA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2016.03.074DOI Listing
June 2016

Advancing a vaccine to prevent human schistosomiasis.

Vaccine 2016 06 29;34(26):2988-2991. Epub 2016 Mar 29.

Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development Houston, TX, USA; Sabin Vaccine Institute, Washington, DC, USA; National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Department of Biology, Baylor University, Waco, TX, USA.

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http://dx.doi.org/10.1016/j.vaccine.2016.03.079DOI Listing
June 2016

Advancing a vaccine to prevent hookworm disease and anemia.

Vaccine 2016 06 31;34(26):3001-3005. Epub 2016 Mar 31.

National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA; Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA; Department of Biology, Baylor University, Waco, TX, USA; Sabin Vaccine Institute, Washington, DC, USA.

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http://dx.doi.org/10.1016/j.vaccine.2016.03.078DOI Listing
June 2016

Human anthelminthic vaccines: Rationale and challenges.

Vaccine 2016 06 9;34(30):3549-55. Epub 2016 May 9.

Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA; Department of Biology, Baylor University, Waco, TX, USA.

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http://dx.doi.org/10.1016/j.vaccine.2016.03.112DOI Listing
June 2016

Modeling the economic and epidemiologic impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting.

Vaccine 2016 Apr 18;34(19):2197-206. Epub 2016 Mar 18.

Public Health Computational and Operational Research (PHICOR), Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA; Global Obesity Prevention Center, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X160032
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http://dx.doi.org/10.1016/j.vaccine.2016.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547742PMC
April 2016

Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection.

PLoS Negl Trop Dis 2016 Apr 5;10(4):e0004586. Epub 2016 Apr 5.

Department of Pathobiological Sciences, LSU School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0004586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821550PMC
April 2016

New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74.

Hum Vaccin Immunother 2015 ;11(5):1251-7

a Centre for Biodiscovery and Molecular Development of Therapeutics; Australian Institute of Tropical Health and Medicine; James Cook University; Cairns , Queensland , Australia.

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http://dx.doi.org/10.4161/21645515.2014.980199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514234PMC
February 2016

Identification of immunodominant antigens for the laboratory diagnosis of toxocariasis.

Trop Med Int Health 2015 Dec 23;20(12):1787-96. Epub 2015 Oct 23.

Baylor College of Medicine, Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA.

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http://dx.doi.org/10.1111/tmi.12607DOI Listing
December 2015

Expression, purification, immunogenicity, and protective efficacy of a recombinant Tc24 antigen as a vaccine against Trypanosoma cruzi infection in mice.

Vaccine 2015 Aug 17;33(36):4505-12. Epub 2015 Jul 17.

Laboratorio de Parasitología, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi", Universidad Autónoma de Yucatán, 97000 Mérida, Yucatán, Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.07.017DOI Listing
August 2015

Neglected tropical diseases among the Association of Southeast Asian Nations (ASEAN): overview and update.

PLoS Negl Trop Dis 2015 Apr 16;9(4):e0003575. Epub 2015 Apr 16.

Tropical Infectious Diseases Research and Education Centre, Department of Medical Microbiology, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.plos.org/10.1371/journal.pntd.0003575
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http://dx.doi.org/10.1371/journal.pntd.0003575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400050PMC
April 2015

Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate.

Hum Vaccin Immunother 2014 30;10(3):648-58. Epub 2013 Dec 30.

Lindsley F Kimball Research Institute; New York Blood Center; New York, NY USA; Key Laboratory of Medical Molecular Virology of MOE/MOH; Shanghai Medical College and Institute of Medical Microbiology; Fudan University; Shanghai, PR China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130269PMC
http://dx.doi.org/10.4161/hv.27464DOI Listing
March 2015

The Gulf of Mexico: a "hot zone" for neglected tropical diseases?

PLoS Negl Trop Dis 2015 Feb 26;9(2):e0003481. Epub 2015 Feb 26.

School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0003481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342336PMC
February 2015

Development of chagas cardiac manifestations among Texas blood donors.

Am J Cardiol 2015 Jan 14;115(1):113-7. Epub 2014 Oct 14.

Section of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2014.09.050DOI Listing
January 2015

The Onchocerciasis Vaccine for Africa--TOVA--Initiative.

PLoS Negl Trop Dis 2015 Jan 29;9(1):e0003422. Epub 2015 Jan 29.

Laboratory of Molecular Parasitology, Lindsley F Kimball Research Institute, New York Blood Center, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0003422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310604PMC
January 2015

Vaccines against neglected tropical diseases: promising interventions to rescue the poorest populations in the Americas.

Immunotherapy 2014 ;6(2):117-9

Sabin Vaccine Institute & Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.2217/imt.13.159DOI Listing
October 2014

A scoping review and prevalence analysis of soil-transmitted helminth infections in Honduras.

PLoS Negl Trop Dis 2014 23;8(1):e2653. Epub 2014 Jan 23.

School of Microbiology, National Autonomous University of Honduras (UNAH), Tegucigalpa, Honduras.

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http://dx.doi.org/10.1371/journal.pntd.0002653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900402PMC
September 2014

Neglected tropical diseases in Central America and Panama: review of their prevalence, populations at risk and impact on regional development.

Int J Parasitol 2014 Aug 15;44(9):597-603. Epub 2014 May 15.

Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States; Department of Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States; Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.ijpara.2014.04.001DOI Listing
August 2014

Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model.

Int J Parasitol 2014 Aug 5;44(9):637-46. Epub 2014 Jun 5.

Department of Microbiology and Immunology, Jefferson Medical College, Thomas Jefferson University, 233 S. 10th Street, Philadelphia, PA 19107, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijpara.2014.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118642PMC
August 2014

Toxocariasis in North America: a systematic review.

PLoS Negl Trop Dis 2014 Aug 28;8(8):e3116. Epub 2014 Aug 28.

Departments of Medicine, Pediatrics, and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America; Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0003116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148222PMC
August 2014

Calling for rapid development of a safe and effective MERS vaccine.

Microbes Infect 2014 Jul 12;16(7):529-31. Epub 2014 Jun 12.

Lindsley F. Kimball Research Institute, New York Blood Center, 310 East 67th Street, New York, NY, USA; Key Laboratory of Medical Molecular Virology of MOE/MOH, Shanghai Medical College and Institute of Medical Microbiology, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2014.05.002DOI Listing
July 2014

An unfolding tragedy of Chagas disease in North America.

PLoS Negl Trop Dis 2013 31;7(10):e2300. Epub 2013 Oct 31.

National School of Tropical Medicine at Baylor College of Medicine and the Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, Texas, United States of America ; James A. Baker III Institute for Public Policy, Rice University, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0002300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814410PMC
June 2014

Advancing a multivalent 'Pan-anthelmintic' vaccine against soil-transmitted nematode infections.

Expert Rev Vaccines 2014 Mar 6;13(3):321-31. Epub 2014 Jan 6.

Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Baylor College of Medicine , Houston, TX , USA.

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http://dx.doi.org/10.1586/14760584.2014.872035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934375PMC
March 2014

Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis.

Hum Vaccin Immunother 2013 Nov 30;9(11):2342-50. Epub 2013 Jul 30.

Departments of Pediatrics and Molecular Virology and Microbiology; National School of Tropical Medicine; Baylor College of Medicine; Houston, TX USA; Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development; Houston, TX USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981843PMC
http://dx.doi.org/10.4161/hv.25787DOI Listing
November 2013

New vaccines for neglected parasitic diseases and dengue.

Transl Res 2013 Sep 8;162(3):144-55. Epub 2013 Apr 8.

Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Baylor College of Medicine, Houston 77030, Tex., USA.

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http://dx.doi.org/10.1016/j.trsl.2013.03.006DOI Listing
September 2013

Global economic burden of Chagas disease: a computational simulation model.

Lancet Infect Dis 2013 Apr 8;13(4):342-8. Epub 2013 Feb 8.

Public Health Computational and Operations Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/S1473-3099(13)70002-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763184PMC
April 2013

The potential economic value of a cutaneous leishmaniasis vaccine in seven endemic countries in the Americas.

Vaccine 2013 Jan 20;31(3):480-6. Epub 2012 Nov 20.

Public Health Computational and Operational Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.vaccine.2012.11.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763201PMC
January 2013

Modeling the economic value of a Chagas' disease therapeutic vaccine.

Hum Vaccin Immunother 2012 Sep 16;8(9):1293-301. Epub 2012 Aug 16.

Public Health Computational and Operations Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.4161/hv.20966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579910PMC
September 2012

Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects.

Expert Rev Vaccines 2012 Sep;11(9):1043-55

Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Departments of Pediatrics (Section of Pediatric Tropical Medicine) and Molecular Virology & Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1586/erv.12.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819810PMC
September 2012

Advances in vaccines against neglected tropical diseases: enhancing physical stability of a recombinant hookworm vaccine through biophysical and formulation studies.

Hum Vaccin Immunother 2012 Jun 12;8(6):765-76. Epub 2012 Apr 12.

Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.

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http://www.tandfonline.com/doi/abs/10.4161/hv.19726
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http://dx.doi.org/10.4161/hv.19726DOI Listing
June 2012

Ac-AP-12, a novel factor Xa anticoagulant peptide from the esophageal glands of adult Ancylostoma caninum.

Mol Biochem Parasitol 2011 May 18;177(1):42-8. Epub 2011 Jan 18.

Department of Microbiology, Immunology and Tropical Medicine, The George Washington University and the Sabin Vaccine Institute, Washington, DC 20037, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01666851110003
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http://dx.doi.org/10.1016/j.molbiopara.2011.01.008DOI Listing
May 2011

Expression, purification, crystallization and preliminary X-ray analysis of a truncated soluble domain of human glioma pathogenesis-related protein 1.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 Nov 28;66(Pt 11):1487-9. Epub 2010 Oct 28.

L2 Diagnostics LLC, 300 George Street, New Haven, CT 06511, USA.

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http://dx.doi.org/10.1107/S1744309110035669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001655PMC
November 2010

The unfinished public health agenda of chagas disease in the era of globalization.

PLoS Negl Trop Dis 2009 Jul 7;3(7):e470. Epub 2009 Jul 7.

Hospital Infantil de México, Federico Gómez, México, DF, México.

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https://dx.plos.org/10.1371/journal.pntd.0000470
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http://dx.doi.org/10.1371/journal.pntd.0000470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700253PMC
July 2009

Model for product development of vaccines against neglected tropical diseases: a vaccine against human hookworm.

Expert Rev Vaccines 2008 Dec;7(10):1481-92

Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, 2300 Eye Street NW, Ross Hall, Washington, DC 20037, USA.

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http://www.tandfonline.com/doi/full/10.1586/14760584.7.10.14
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December 2008

The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination.

PLoS Negl Trop Dis 2008 Sep 24;2(9):e300. Epub 2008 Sep 24.

Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University and Sabin Vaccine Institute, Washington, DC, USA.

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http://dx.doi.org/10.1371/journal.pntd.0000300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553488PMC
September 2008

In vitro cultured peripheral blood mononuclear cells from patients with chronic schistosomiasis mansoni show immunomodulation of cyclin D1,2,3 in the presence of soluble egg antigens.

Microbes Infect 2007 Oct 11;9(12-13):1493-9. Epub 2007 Aug 11.

Laboratório de Imunologia Celular e Molecular, Instituto René Rachou/FIOCRUZ, Fundação Oswaldo Cruz, Avenida Augusto de Lima 1715, Barro Preto, 30190-002 Belo Horizonte, MG, Brazil.

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http://dx.doi.org/10.1016/j.micinf.2007.08.004DOI Listing
October 2007

Reduction of worm fecundity and canine host blood loss mediates protection against hookworm infection elicited by vaccination with recombinant Ac-16.

Clin Vaccine Immunol 2007 Mar 31;14(3):281-7. Epub 2007 Jan 31.

Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Ross Hall Room 727, 2300 Eye St. NW, Washington, DC 20037, USA.

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http://dx.doi.org/10.1128/CVI.00404-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828853PMC
March 2007

Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral and cellular responses after vaccination in the Sprague Dawley rat.

Hum Vaccin 2005 May-Jun;1(3):123-8. Epub 2005 May 20.

Department of Microbiology and Tropical Medicine, The George Washington University Medical Center, Washington, DC 20037, USA.

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http://dx.doi.org/10.4161/hv.1.3.1924DOI Listing
October 2006

New technologies for the control of human hookworm infection.

Trends Parasitol 2006 Jul 18;22(7):327-31. Epub 2006 May 18.

Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, 2300 I Street, NW Washington, DC 20037, USA.

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http://dx.doi.org/10.1016/j.pt.2006.05.004DOI Listing
July 2006

An ounce of prevention on a budget: a nonprofit approach to developing vaccines against neglected diseases.

Expert Rev Vaccines 2006 Apr;5(2):189-98

The George Washington University, The Human Hookworm Vaccine Initiative, Department of Microbiology, Immunology and Tropical Medicine, 2300 Eye Street NW, Ross Hall Room 733, Washington, DC 20037, USA.

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http://dx.doi.org/10.1586/14760584.5.2.189DOI Listing
April 2006