Maria Dusinska

Maria Dusinska

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Maria Dusinska

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In Vitro Approaches for Assessing the Genotoxicity of Nanomaterials.

Methods Mol Biol 2019 ;1894:83-122

Department of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.

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http://dx.doi.org/10.1007/978-1-4939-8916-4_6DOI Listing
January 2019

Coffee and oxidative stress: a human intervention study.

Eur J Nutr 2018 Mar 17;57(2):533-544. Epub 2016 Nov 17.

NorGenoTech AS, Totenvegen 2049, 2848, Skreia, Norway.

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http://dx.doi.org/10.1007/s00394-016-1336-4DOI Listing
March 2018

Nanomedicine and epigenome. Possible health risks.

Food Chem Toxicol 2017 Nov 11;109(Pt 1):780-796. Epub 2017 Jul 11.

Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, 845 05 Bratislava, Slovakia.

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http://dx.doi.org/10.1016/j.fct.2017.07.020DOI Listing
November 2017

Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing?

Food Chem Toxicol 2017 Nov 26;109(Pt 1):797-811. Epub 2017 Aug 26.

Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2017.08.030DOI Listing
November 2017

Sensitive detection of DNA oxidation damage induced by nanomaterials.

Free Radic Biol Med 2017 06 2;107:69-76. Epub 2017 Feb 2.

Norwegian Institute for Air Research, Department of Environmental Chemistry, Kjeller, Norway.

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.02.001DOI Listing
June 2017

In vitro genotoxicity testing of four reference metal nanomaterials, titanium dioxide, zinc oxide, cerium oxide and silver: towards reliable hazard assessment.

Mutagenesis 2017 01 12;32(1):117-126. Epub 2016 Nov 12.

Health Effects Group, Department of Environmental Chemistry, NILU- Norwegian Institute for Air Research, Kjeller 2007, Norway,

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http://dx.doi.org/10.1093/mutage/gew060DOI Listing
January 2017

NanoGenotoxicology: present and the future.

Mutagenesis 2017 01;32(1):1-4

Health Effects Group, Department of Environmental Chemistry, NILU- Norwegian Institute for Air Research, N-2027 Kjeller, Norway

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http://dx.doi.org/10.1093/mutage/gew066DOI Listing
January 2017

Genetic variation in the major mitotic checkpoint genes associated with chromosomal aberrations in healthy humans.

Cancer Lett 2016 10 15;380(2):442-6. Epub 2016 Jul 15.

Department of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S03043835163040
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http://dx.doi.org/10.1016/j.canlet.2016.07.011DOI Listing
October 2016

Automotive airborne brake wear debris nanoparticles and cytokinesis-block micronucleus assay in peripheral blood lymphocytes: A pilot study.

Environ Res 2016 07 29;148:443-449. Epub 2016 Apr 29.

Health Effects Laboratory, Department of Environmental Chemistry, NILU-Norwegian Institute for Air Research, Instituttveien 18, 2007 Kjeller, Norway.

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http://dx.doi.org/10.1016/j.envres.2016.04.022DOI Listing
July 2016

Multi-walled carbon nanotubes (NM401) induce ROS-mediated HPRT mutations in Chinese hamster lung fibroblasts.

Environ Res 2016 Apr 9;146:185-90. Epub 2016 Jan 9.

Grup de Mutagènesi, Departament de Genètica i de Microbiologia, Facultat de Biociències, Universitat Autònoma de Barcelona, Bellaterra, Spain; CIBER Epidemiología y Salud Pública, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00139351163000
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http://dx.doi.org/10.1016/j.envres.2016.01.004DOI Listing
April 2016

Functionalized porous silica&maghemite core-shell nanoparticles for applications in medicine: design, synthesis, and immunotoxicity.

Croat Med J 2016 Apr;57(2):165-78

Daniel Horak, Department of Polymer Particles, Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Heyrovskeho Sq. 2 , 162 06 Prague 6, Czech Republic,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856187PMC
April 2016

Interactions of DNA repair gene variants modulate chromosomal aberrations in healthy subjects.

Carcinogenesis 2015 Nov 8;36(11):1299-306. Epub 2015 Sep 8.

Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), 69120 Heidelberg, Germany, Center for Primary Health Care Research, Lund University, 20506 Malmö, Sweden and.

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http://dx.doi.org/10.1093/carcin/bgv127DOI Listing
November 2015

The use of the comet assay for the evaluation of the genotoxicity of nanomaterials.

Front Genet 2015 10;6:239. Epub 2015 Jul 10.

Health Effects Laboratory, Department of Environmental Chemistry, NILU-Norwegian Institute for Air Research Kjeller, Norway.

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http://dx.doi.org/10.3389/fgene.2015.00239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498100PMC
July 2015

Iron oxide nanoparticle toxicity testing using high-throughput analysis and high-content imaging.

Nanotoxicology 2015 May;9 Suppl 1:87-94

Institute for Health and Consumer Protection European Commission, Joint Research Centre , Ispra (VA) , Italy .

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http://dx.doi.org/10.3109/17435390.2013.816797DOI Listing
May 2015

Biological impact assessment of nanomaterial used in nanomedicine. introduction to the NanoTEST project.

Nanotoxicology 2015 May 16;9 Suppl 1:5-12. Epub 2013 Sep 16.

University Institute of Pathology, CHUV-UNIL , Lausanne , Switzerland .

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http://dx.doi.org/10.3109/17435390.2013.826743DOI Listing
May 2015

Toxicity screenings of nanomaterials: challenges due to interference with assay processes and components of classic in vitro tests.

Nanotoxicology 2015 May;9 Suppl 1:13-24

Univ Paris Diderot, (Sorbonne Paris Cité), UMR 8251 CNRS, Unit of Functional and Adaptive Biology (BFA), Laboratory of Molecular and Cellular Responses to Xenobiotics (RMCX) , 75205 Paris cedex 13 , France .

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http://dx.doi.org/10.3109/17435390.2013.829590DOI Listing
May 2015

NanoTEST in a Nutshell.

Nanotoxicology 2015 May;9 Suppl 1:1-4

Norwegian Institute for Air Research , Kjeller , Norway and.

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http://dx.doi.org/10.3109/17435390.2014.991774DOI Listing
May 2015

Metabolic gene variants associated with chromosomal aberrations in healthy humans.

Genes Chromosomes Cancer 2015 Apr 27;54(4):260-6. Epub 2015 Jan 27.

Department of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1002/gcc.22239DOI Listing
April 2015

Can the comet assay be used reliably to detect nanoparticle-induced genotoxicity?

Environ Mol Mutagen 2015 Mar 8;56(2):82-96. Epub 2014 Dec 8.

Nanosafety and Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/em.21933DOI Listing
March 2015

Nanoparticles in food. Epigenetic changes induced by nanomaterials and possible impact on health.

Food Chem Toxicol 2015 Mar 29;77:64-73. Epub 2014 Dec 29.

Health Effects Laboratory, Department of Environmental Chemistry (MILK), NILU- Norwegian Institute for Air Research, 2027 Kjeller, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2014.12.015DOI Listing
March 2015

Lessons learned from research on air pollution and other particles in the toxicology of nanomaterials and vice versa.

Environ Mol Mutagen 2015 Mar 8;56(2):77-81. Epub 2015 Jan 8.

Institute of Public Health, Section of Environmental Health, University of Copenhagen, Copenhagen K, Denmark.

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http://dx.doi.org/10.1002/em.21930DOI Listing
March 2015

Effect of silver nanoparticles on mitogen-activated protein kinases activation: role of reactive oxygen species and implication in DNA damage.

Mutagenesis 2015 Jan;30(1):59-66

Health Effects Laboratory, Environmental Chemistry Department, NILU-Norwegian Institute for Air Research, PO Box 100, 2027 Kjeller, Norway.

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http://dx.doi.org/10.1093/mutage/geu057DOI Listing
January 2015

Critical factors to be considered when testing nanomaterials for genotoxicity with the comet assay.

Mutagenesis 2015 Jan;30(1):85-8

Health Effects Laboratory, Department of Environmental Chemistry, NILU-Norwegian Institute for Air Research, Instituttveien 18, 2007 Kjeller, Norway,

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http://dx.doi.org/10.1093/mutage/geu077DOI Listing
January 2015

Genotoxic and mutagenic potential of nitramines.

Environ Res 2014 Oct 18;134:39-45. Epub 2014 Jul 18.

Health Effects Laboratory, MILK, NILU - Norwegian Institute for Air Research, 2007 Kjeller, Norway.

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http://dx.doi.org/10.1016/j.envres.2014.06.008DOI Listing
October 2014

NBN and XRCC3 genetic variants in childhood acute lymphoblastic leukaemia.

Cancer Epidemiol 2014 Oct 27;38(5):563-8. Epub 2014 Aug 27.

Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canep.2014.08.002DOI Listing
October 2014

On the search for an intelligible comet assay descriptor.

Front Genet 2014 17;5:217. Epub 2014 Jul 17.

Department of Nutrition, Faculty of Medicine, University of Oslo Oslo, Norway.

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http://dx.doi.org/10.3389/fgene.2014.00217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101262PMC
August 2014

Mechanisms of genotoxicity. A review of in vitro and in vivo studies with engineered nanoparticles.

Nanotoxicology 2014 May 20;8(3):233-78. Epub 2013 Mar 20.

NILU-Norwegian Institute for Air Research, MILK, Health Effects Laboratory , Kjeller , Norway.

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http://dx.doi.org/10.3109/17435390.2013.773464DOI Listing
May 2014

The comet assay as a tool for human biomonitoring studies: the ComNet project.

Mutat Res Rev Mutat Res 2014 Jan-Mar;759:27-39. Epub 2013 Oct 31.

Unit of Clinical and Molecular Epidemiology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Pisana, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.mrrev.2013.10.001DOI Listing
May 2014

Genotoxicity of silver and titanium dioxide nanoparticles in bone marrow cells of rats in vivo.

Toxicology 2014 Jan 7;315:86-91. Epub 2013 Dec 7.

Institute of Nuclear Chemistry and Technology, Warsaw, Poland; Institute of Rural Health, Lublin, Poland.

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https://linkinghub.elsevier.com/retrieve/pii/S0300483X130032
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http://dx.doi.org/10.1016/j.tox.2013.11.012DOI Listing
January 2014

Ag nanoparticles: size- and surface-dependent effects on model aquatic organisms and uptake evaluation with NanoSIMS.

Nanotoxicology 2013 Nov 23;7(7):1168-78. Epub 2012 Aug 23.

Department of Environment and Agrobiotechnologies, Centre de Recherche Public-Gabriel Lippmann , 41 rue du Brill, Belvaux , Luxembourg.

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http://dx.doi.org/10.3109/17435390.2012.715312DOI Listing
November 2013

Screening for potential hazard effects from four nitramines on human eye and skin.

Toxicol In Vitro 2013 Jun 14;27(4):1205-10. Epub 2013 Feb 14.

Health Effects Laboratory, Department of Environmental Chemistry, NILU-Norwegian Institute for Air Research, Instituttveien 18, Kjeller, Norway.

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http://dx.doi.org/10.1016/j.tiv.2013.02.004DOI Listing
June 2013

Oxidative DNA damage corresponds to the long term survival of human cells treated with silver nanoparticles.

Toxicol Lett 2013 May 18;219(2):151-9. Epub 2013 Mar 18.

Centre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Warszawa, Poland.

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http://dx.doi.org/10.1016/j.toxlet.2013.03.006DOI Listing
May 2013

Toxicological aspects for nanomaterial in humans.

Methods Mol Biol 2013 ;948:1-12

NILU, CEE, Health Effects Group, Kjeller, Norway.

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http://dx.doi.org/10.1007/978-1-62703-140-0_1DOI Listing
March 2013

Approaches to integrated monitoring for environmental health impact assessment.

Environ Health 2012 Nov 21;11:88. Epub 2012 Nov 21.

NILU - Norwegian Institute for Air Research, Instituttveien 18, 2027, Kjeller, Norway.

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http://dx.doi.org/10.1186/1476-069X-11-88DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526392PMC
November 2012

Can standard genotoxicity tests be applied to nanoparticles?

J Toxicol Environ Health A 2012 ;75(13-15):800-6

NILU-Norwegian Institute for Air Research, CEE, Health Effects Group, Kjeller, Norway.

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http://dx.doi.org/10.1080/15287394.2012.690326DOI Listing
October 2012

Genotoxicity testing of PLGA-PEO nanoparticles in TK6 cells by the comet assay and the cytokinesis-block micronucleus assay.

Mutat Res 2012 Oct 17;748(1-2):42-7. Epub 2012 Jul 17.

Slovak Medical University, Limbova 14, 83303 Bratislava, Slovakia.

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http://dx.doi.org/10.1016/j.mrgentox.2012.06.012DOI Listing
October 2012

Gentiana asclepiadea exerts antioxidant activity and enhances DNA repair of hydrogen peroxide- and silver nanoparticles-induced DNA damage.

Food Chem Toxicol 2012 Sep 18;50(9):3352-9. Epub 2012 Jun 18.

Department of Genetics, Faculty of Natural Sciences, Comenius University, Mlynská dolina, Bratislava 842 15, Slovakia.

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http://dx.doi.org/10.1016/j.fct.2012.06.017DOI Listing
September 2012

Bladder cancer, a review of the environmental risk factors.

Environ Health 2012 Jun 28;11 Suppl 1:S11. Epub 2012 Jun 28.

Institute of Biochemistry, Nutrition and Health Protection, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského 9, SK-812 37 Bratislava, Slovak Republic.

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http://dx.doi.org/10.1186/1476-069X-11-S1-S11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388449PMC
June 2012

Nanoparticles in the environment: assessment using the causal diagram approach.

Environ Health 2012 Jun 28;11 Suppl 1:S13. Epub 2012 Jun 28.

Amity University, Lucknow Campus, Viraj Khand 5, Lucknow-226010, UP, India.

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http://dx.doi.org/10.1186/1476-069X-11-S1-S13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388445PMC
June 2012

DNA alkylation lesions and their repair in human cells: modification of the comet assay with 3-methyladenine DNA glycosylase (AlkD).

Toxicol Lett 2012 Jan 14;208(1):76-81. Epub 2011 Oct 14.

Department of Genetics, Faculty of Natural Sciences, Comenius University, Mlynska dolina, 842 15 Bratislava, Slovakia.

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http://dx.doi.org/10.1016/j.toxlet.2011.10.005DOI Listing
January 2012

Vitamin C levels in blood are influenced by polymorphisms in glutathione S-transferases.

Eur J Nutr 2011 Sep 9;50(6):437-46. Epub 2010 Dec 9.

Department of Experimental and Applied Genetics, Slovak Medical University, Limbova 12, 833 03 Bratislava, Slovakia.

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http://dx.doi.org/10.1007/s00394-010-0147-2DOI Listing
September 2011

Cytotoxic and genotoxic effect of methanolic flower extract from Gentiana asclepiadea on COS 1 cells.

Neuro Endocrinol Lett 2010 ;31 Suppl 2:21-5

Department of Genetics, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.

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June 2011

Safety assessment of nanoparticles cytotoxicity and genotoxicity of metal nanoparticles in vitro.

J Biomed Nanotechnol 2011 Feb;7(1):20-1

Health Effects Group, Norwegian Institute for Air Research (NILU), Instituttvn. 18, N-2027 Kjeller, Norway.

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February 2011

The importance of life cycle concepts for the development of safe nanoproducts.

Toxicology 2010 Mar 16;269(2-3):160-9. Epub 2009 Dec 16.

Empa, Swiss Federal Laboratories for Materials Testing and Research, Technology and Society Laboratory, Lerchenfeldstrasse 5, CH-9014 St. Gallen, Switzerland.

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http://dx.doi.org/10.1016/j.tox.2009.12.012DOI Listing
March 2010

Use of single cell gel electrophoresis assays for the detection of DNA-protective effects of dietary factors in humans: recent results and trends.

Mutat Res 2009 Jan-Feb;681(1):68-79. Epub 2008 Aug 5.

Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.mrrev.2008.07.004DOI Listing
April 2009

DNA-protective effects of sumach (Rhus coriaria L.), a common spice: results of human and animal studies.

Mutat Res 2009 Feb 30;661(1-2):10-7. Epub 2008 Oct 30.

Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.

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http://linkinghub.elsevier.com/retrieve/pii/S002751070800251
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http://dx.doi.org/10.1016/j.mrfmmm.2008.10.009DOI Listing
February 2009

Micronuclei and chromosomal aberrations, important markers of ageing: possible association with XPC and XPD polymorphisms.

Mutat Res 2009 Feb 5;661(1-2):35-40. Epub 2008 Nov 5.

Research Base of the Slovak Medical University, Limbová 14, 833 01 Bratislava, Slovak Republic.

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http://dx.doi.org/10.1016/j.mrfmmm.2008.10.017DOI Listing
February 2009

The comet assay in human biomonitoring: gene-environment interactions.

Mutagenesis 2008 May 7;23(3):191-205. Epub 2008 Mar 7.

Centre for Ecological Economics, Norwegian Institute of Air Research (NILU), Kjeller, Norway.

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http://dx.doi.org/10.1093/mutage/gen007DOI Listing
May 2008

The relationship between micronuclei in human lymphocytes and selected micronutrients in vegetarians and non-vegetarians.

Mutat Res 2006 Dec 15;611(1-2):64-70. Epub 2006 Sep 15.

Research Base of Slovak Medical University, Institute of Preventive and Clinical Medicine, Limbová 14, 833 01 Bratislava, Slovak Republic.

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http://dx.doi.org/10.1016/j.mrgentox.2006.08.001DOI Listing
December 2006

Genetic predisposition and health effect of occupational exposure to asbestos.

Neuro Endocrinol Lett 2006 Dec;27 Suppl 2:100-3

Research Base of Slovak Medical University, Bratislava, Slovakia.

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December 2006

Importance of diet in protection against oxidative damage.

Neuro Endocrinol Lett 2006 Dec;27 Suppl 2:112-5

Research Base of Slovak Medical University, Bratislava, Slovakia.

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December 2006

Possible involvement of XPA in repair of oxidative DNA damage deduced from analysis of damage, repair and genotype in a human population study.

Mutagenesis 2006 May 13;21(3):205-11. Epub 2006 Apr 13.

Department of Experimental and Applied Medicine, Institute of Preventive and Clinical Medicine, Research Base of Slovak Medical University Limbová 14, Bratislava, Slovakia.

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http://dx.doi.org/10.1093/mutage/gel016DOI Listing
May 2006

Immunological monitoring in workers occupationally exposed to asbestos.

Toxicology 2005 Jan;206(2):299-308

Research Base of the Slovak Medical University, Institute of Preventive and Clinical Medicine, Department of Clinical Immunology, Limbova 12, 833 01 Bratislava, Slovak Republic.

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http://dx.doi.org/10.1016/j.tox.2004.09.004DOI Listing
January 2005

Genotoxic effects of asbestos in humans.

Mutat Res 2004 Sep;553(1-2):91-102

Institute of Preventive and Clinical Medicine, Slovak Medical University, Limbová 12, Bratislava 83303, Slovak Republic.

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http://dx.doi.org/10.1016/j.mrfmmm.2004.06.027DOI Listing
September 2004

Does occupational exposure to mineral fibres cause DNA or chromosome damage?

Mutat Res 2004 Sep;553(1-2):103-10

Institute of Preventive and Clinical Medicine, Research Base of the Slovak Medical University, Limbova 12, 833 03 Bratislava, Slovak Republic.

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http://dx.doi.org/10.1016/j.mrfmmm.2004.06.029DOI Listing
September 2004

Immunomodulatory effects of mineral fibres in occupationally exposed workers.

Mutat Res 2004 Sep;553(1-2):111-24

Research Base of the Slovak Medical University, Institute of Preventive and Clinical Medicine, Limbova 12, 833 03 Bratislava, Slovak Republic.

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http://dx.doi.org/10.1016/j.mrfmmm.2004.06.030DOI Listing
September 2004

DNA damage and repair measured in different genomic regions using the comet assay with fluorescent in situ hybridization.

Mutagenesis 2004 Jul;19(4):269-76

Cancer Research Institute, Vlárska 7, 833 91 Bratislava, Slovakia, Institute of Preventive and Clinical Medicine, Slovak Medical University, Limbová 12, 833 03 Bratislava, Slovakia.

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July 2004

Seasonal changes in markers of oxidative damage to lipids and DNA; correlations with seasonal variation in diet.

Mutat Res 2004 Jul;551(1-2):135-44

Institute of Preventive and Clinical Medicine, Slovak Medical University, Limbová 12, Bratislava 83303, Slovak Republic.

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http://dx.doi.org/10.1016/j.mrfmmm.2004.02.021DOI Listing
July 2004

Does a vegetarian diet influence genomic stability?

Eur J Nutr 2004 Feb 6;43(1):32-8. Epub 2004 Jan 6.

Institute of Preventive and Clinical Medicine, Limbová 14, 83301, Bratislava, Slovakia.

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http://dx.doi.org/10.1007/s00394-004-0436-8DOI Listing
February 2004

Binary exposure of A549 cells to benzo[a]pyrene and UVC radiation yields enhanced DNA damage in the comet assay but no enhancement of 8-oxo-deoxyguanosine.

Environ Mol Mutagen 2003 ;42(3):228-30

Department of Experimental and Applied Genetics, Institute of Preventive and Clinical Medicine, Bratislava, Slovakia.

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http://dx.doi.org/10.1002/em.10191DOI Listing
December 2003

Oxidation of cellular DNA measured with the comet assay.

Methods Mol Biol 2002 ;186:147-59

Rowett Research Institute, Aberdeen, UK.

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http://dx.doi.org/10.1385/1-59259-173-6:147DOI Listing
August 2003