Maria Arcila

Maria Arcila

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Maria Arcila

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Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes.

J Thorac Oncol 2019 Oct 19;14(10):1784-1793. Epub 2019 Jun 19.

Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764905PMC
October 2019

Recurrent somatic mutations in NK-cell enteropathy.

Blood 2019 Sep 5;134(12):986-991. Epub 2019 Aug 5.

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD; and.

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http://dx.doi.org/10.1182/blood.2019001443DOI Listing
September 2019

Lessons learned from routine, targeted assessment of liquid biopsies for T790M resistance mutation in patients with mutant lung cancers.

Acta Oncol 2019 Jul 26:1-6. Epub 2019 Jul 26.

b Diagnostic Molecular Pathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center , New York , NY , USA.

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http://dx.doi.org/10.1080/0284186X.2019.1645354DOI Listing
July 2019

Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers.

J Thorac Oncol 2019 May 1;14(5):802-815. Epub 2019 Mar 1.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.12.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486868PMC
May 2019

Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with -Mutant Lung Cancers.

Clin Cancer Res 2019 Feb 25;25(3):1063-1069. Epub 2018 Jul 25.

Department of Medicine, Division of Solid Tumor Oncology, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347551PMC
February 2019

Biomarker Testing for Patients With Advanced Non-Small Cell Lung Cancer: Real-World Issues and Tough Choices.

Am Soc Clin Oncol Educ Book 2019 Jan 17;39:531-542. Epub 2019 May 17.

4 City of Hope Comprehensive Cancer Center, Duarte, CA.

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http://dx.doi.org/10.1200/EDBK_237863DOI Listing
January 2019

JAK/MAP kinase pathway activation and TP53 mutations in acute leukemia with megakaryocytic and erythroid differentiation.

Leukemia 2018 08 24;32(8):1842-1845. Epub 2018 Apr 24.

Hematopathology Diagnostic Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41375-018-0145-6DOI Listing
August 2018

Ado-Trastuzumab Emtansine for Patients With HER2-Mutant Lung Cancers: Results From a Phase II Basket Trial.

J Clin Oncol 2018 08 10;36(24):2532-2537. Epub 2018 Jul 10.

Bob T. Li, Ronglai Shen, Darren Buonocore, Zachary T. Olah, Ai Ni, Michelle S. Ginsberg, Gary A. Ulaner, Michael Offin, Daniel Feldman, Helen H. Won, Edyta B. Brzostowski, Gregory J. Riely, David B. Solit, David M. Hyman, Alexander Drilon, Charles M. Rudin, Michael F. Berger, Jose Baselga, Maurizio Scaltriti, Maria E. Arcila, and Mark G. Kris, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College, New York, NY; Bob T. Li, Nick Pavlakis, and Stephen Clarke, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia; and Todd Hembrough, Fabiola Cecchi, and Sarit Schwartz, NantOmics, Rockville, MD.

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http://ascopubs.org/doi/10.1200/JCO.2018.77.9777
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http://dx.doi.org/10.1200/JCO.2018.77.9777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366814PMC
August 2018

Multicenter Prospective Phase II Trial of Neoadjuvant Dose-Dense Gemcitabine Plus Cisplatin in Patients With Muscle-Invasive Bladder Cancer.

J Clin Oncol 2018 07 9;36(19):1949-1956. Epub 2018 May 9.

Gopa Iyer, Bernard H. Bochner, Guido Dalbagni, S. Machele Donat, Harry W. Herr, Irina Ostrovnaya, Hikmat Al-Ahmadie, Maria E. Arcila, Jamie C. Riches, Andreas Meier, Caitlin Bourque, Maha Shady, Helen Won, Brooke E. Kania, Mariel E. Boyd, Catharine K. Cipolla, Ashley M. Regazzi, Asia S. McCoy, Hebert Alberto Vargas, Michael F. Berger, David B. Solit, Jonathan E. Rosenberg, and Dean F. Bajorin, Memorial Sloan Kettering Cancer Center; Gopa Iyer, Bernard H. Bochner, Guido Dalbagni, S. Machele Donat, Harry W. Herr, Hikmat Al-Ahmadie, David B. Solit, and Dean F. Bajorin, Weill Cornell Medical College; Arjun V. Balar, William C. Huang, Samir S. Taneja, and Daniela Delbeau, New York University Langone Medical Center, New York, NY; and Matthew I. Milowsky, Michael Woods, Tracy L. Rose, and William Y. Kim, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC.

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http://dx.doi.org/10.1200/JCO.2017.75.0158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049398PMC
July 2018

Novel Modification of HistoGel-Based Cell Block Preparation Method: Improved Sufficiency for Molecular Studies.

Arch Pathol Lab Med 2018 Apr 2;142(4):529-535. Epub 2017 Nov 2.

From the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York. Drs Rekhtman and Buonocore contributed equally in the preparation of this article and should be considered as cofirst authors.

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http://dx.doi.org/10.5858/arpa.2017-0030-OADOI Listing
April 2018

The value of cell-free DNA for molecular pathology.

J Pathol 2018 04 12;244(5):616-627. Epub 2018 Mar 12.

Marie-José and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1002/path.5048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656375PMC
April 2018

Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing.

J Clin Oncol 2018 03 16;36(7):633-641. Epub 2018 Jan 16.

Hira Rizvi, Francisco Sanchez-Vega, Konnor La, Walid Chatila, Philip Jonsson, Darragh Halpenny, Andrew Plodkowski, Niamh Long, Jennifer L. Sauter, Natasha Rekhtman, Travis Hollmann, Ronglai Shen, Ai Ni, Kathryn C. Arbour, Taha Merghoub, Jedd Wolchok, Jamie E. Chaft, Mark G. Kris, Charles M. Rudin, Nicholas D. Socci, Michael F. Berger, Barry S. Taylor, Ahmet Zehir, David B. Solit, Maria E. Arcila, Marc Ladanyi, Gregory J. Riely, Nikolaus Schultz, and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center; Taha Merghoub, Jedd Wolchok, Alexandra Snyder, Jamie E. Chaft, Mark G. Kris, Charles M. Rudin, Gregory J. Riely, and Matthew D. Hellmann, Weill Cornell Medical College, New York, NY; Kurt A. Schalper, Yale School of Medicine, New Haven, CT; Justin F. Gainor, Massachusetts General Hospital, Boston, MA; and Alexandra Snyder, Adaptive Biotechnologies, Seattle, WA.

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http://dx.doi.org/10.1200/JCO.2017.75.3384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075848PMC
March 2018

Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology.

Arch Pathol Lab Med 2018 Mar 22;142(3):321-346. Epub 2018 Jan 22.

From the Departments of Pathology (Drs Lindeman and Sholl) and Medicine (Dr Kwiatkowski), Brigham and Women's Hospital, Boston, Massachusetts; the Cancer Center (Dr Bernicker) and the Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas (Dr Cagle); the Department of Pathology, University of Colorado School of Medicine, Denver (Dr Aisner); the Diagnostic and Molecular Pathology Laboratory (Dr Arcila) and the Molecular Diagnostics Service (Dr Ladanyi), Memorial Sloan Kettering Cancer Center, New York, New York; the Department of Pathology & Medicine, Pulmonary, Critical Care and Sleep Medicine, New York, New York (Dr Beasley); the Pathology and Laboratory Quality Center, College of American Pathologists, Northfield, Illinois (Mss Colasacco and Ventura); the Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania (Dr Dacic); the Department of Medicine and Pathology, University of Colorado, Denver (Dr Hirsch); the Department of Pathology, University of Aberdeen, Aberdeen, Scotland (Dr Kerr); the Department of Molecular Pathology, Roswell Park Cancer Institute, Buffalo, New York (Dr Nowak); the Clinical and Scientific Affairs Division, Association for Molecular Pathology, Bethesda, Maryland (Dr Temple-Smolkin); the Molecular Therapeutics and Biomarkers Laboratory, Peter Maccallum Cancer Center, Melbourne, Australia (Dr Solomon); the Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands (Dr Thunnissen); the Department of Laboratory Medicine and Pathobiology, Princess Margaret Cancer Center, Toronto, Ontario, Canada (Dr Tsao); Scientific Affairs, International Association for the Study of Lung Cancer, Aurora, Colorado (Dr Wynes); and the Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan (Dr Yatabe). Dr Souter is in private practice in Wellanport, Ontario, Canada.

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http://dx.doi.org/10.5858/arpa.2017-0388-CPDOI Listing
March 2018

[Efficacy of lycopene intake in primary prevention of prostate cancer: a systematic review of the literature and meta-analysis.]

Arch Esp Urol 2018 Mar;71(2):187-197

Departamento de Urología. Hospital Universitario Fundación Santa Fe de Bogotá y Facultad de Medicina de la Universidad de los Andes. Bogotá D.C. Colombia.

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March 2018

Minimal residual disease detection of myeloma using sequencing of immunoglobulin heavy chain gene VDJ regions.

Semin Hematol 2018 01 23;55(1):13-18. Epub 2018 Feb 23.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00371963173018
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http://dx.doi.org/10.1053/j.seminhematol.2018.02.007DOI Listing
January 2018

Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes.

Cell Stem Cell 2017 09 10;21(3):374-382.e4. Epub 2017 Aug 10.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Medical College, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591073PMC
September 2017

Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Authors:
Ahmet Zehir Ryma Benayed Ronak H Shah Aijazuddin Syed Sumit Middha Hyunjae R Kim Preethi Srinivasan Jianjiong Gao Debyani Chakravarty Sean M Devlin Matthew D Hellmann David A Barron Alison M Schram Meera Hameed Snjezana Dogan Dara S Ross Jaclyn F Hechtman Deborah F DeLair JinJuan Yao Diana L Mandelker Donavan T Cheng Raghu Chandramohan Abhinita S Mohanty Ryan N Ptashkin Gowtham Jayakumaran Meera Prasad Mustafa H Syed Anoop Balakrishnan Rema Zhen Y Liu Khedoudja Nafa Laetitia Borsu Justyna Sadowska Jacklyn Casanova Ruben Bacares Iwona J Kiecka Anna Razumova Julie B Son Lisa Stewart Tessara Baldi Kerry A Mullaney Hikmat Al-Ahmadie Efsevia Vakiani Adam A Abeshouse Alexander V Penson Philip Jonsson Niedzica Camacho Matthew T Chang Helen H Won Benjamin E Gross Ritika Kundra Zachary J Heins Hsiao-Wei Chen Sarah Phillips Hongxin Zhang Jiaojiao Wang Angelica Ochoa Jonathan Wills Michael Eubank Stacy B Thomas Stuart M Gardos Dalicia N Reales Jesse Galle Robert Durany Roy Cambria Wassim Abida Andrea Cercek Darren R Feldman Mrinal M Gounder A Ari Hakimi James J Harding Gopa Iyer Yelena Y Janjigian Emmet J Jordan Ciara M Kelly Maeve A Lowery Luc G T Morris Antonio M Omuro Nitya Raj Pedram Razavi Alexander N Shoushtari Neerav Shukla Tara E Soumerai Anna M Varghese Rona Yaeger Jonathan Coleman Bernard Bochner Gregory J Riely Leonard B Saltz Howard I Scher Paul J Sabbatini Mark E Robson David S Klimstra Barry S Taylor Jose Baselga Nikolaus Schultz David M Hyman Maria E Arcila David B Solit Marc Ladanyi Michael F Berger

Nat Med 2017 08;23(8):1004

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http://dx.doi.org/10.1038/nm0817-1004cDOI Listing
August 2017

Reduced H3K27me3 expression in Merkel cell polyoma virus-positive tumors.

Mod Pathol 2017 06 10;30(6):877-883. Epub 2017 Mar 10.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/modpathol.2017.8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451312PMC
June 2017

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Authors:
Ahmet Zehir Ryma Benayed Ronak H Shah Aijazuddin Syed Sumit Middha Hyunjae R Kim Preethi Srinivasan Jianjiong Gao Debyani Chakravarty Sean M Devlin Matthew D Hellmann David A Barron Alison M Schram Meera Hameed Snjezana Dogan Dara S Ross Jaclyn F Hechtman Deborah F DeLair JinJuan Yao Diana L Mandelker Donavan T Cheng Raghu Chandramohan Abhinita S Mohanty Ryan N Ptashkin Gowtham Jayakumaran Meera Prasad Mustafa H Syed Anoop Balakrishnan Rema Zhen Y Liu Khedoudja Nafa Laetitia Borsu Justyna Sadowska Jacklyn Casanova Ruben Bacares Iwona J Kiecka Anna Razumova Julie B Son Lisa Stewart Tessara Baldi Kerry A Mullaney Hikmat Al-Ahmadie Efsevia Vakiani Adam A Abeshouse Alexander V Penson Philip Jonsson Niedzica Camacho Matthew T Chang Helen H Won Benjamin E Gross Ritika Kundra Zachary J Heins Hsiao-Wei Chen Sarah Phillips Hongxin Zhang Jiaojiao Wang Angelica Ochoa Jonathan Wills Michael Eubank Stacy B Thomas Stuart M Gardos Dalicia N Reales Jesse Galle Robert Durany Roy Cambria Wassim Abida Andrea Cercek Darren R Feldman Mrinal M Gounder A Ari Hakimi James J Harding Gopa Iyer Yelena Y Janjigian Emmet J Jordan Ciara M Kelly Maeve A Lowery Luc G T Morris Antonio M Omuro Nitya Raj Pedram Razavi Alexander N Shoushtari Neerav Shukla Tara E Soumerai Anna M Varghese Rona Yaeger Jonathan Coleman Bernard Bochner Gregory J Riely Leonard B Saltz Howard I Scher Paul J Sabbatini Mark E Robson David S Klimstra Barry S Taylor Jose Baselga Nikolaus Schultz David M Hyman Maria E Arcila David B Solit Marc Ladanyi Michael F Berger

Nat Med 2017 Jun 8;23(6):703-713. Epub 2017 May 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://www.nature.com/doifinder/10.1038/nm.4333
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http://dx.doi.org/10.1038/nm.4333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461196PMC
June 2017

Guidelines for Validation of Next-Generation Sequencing-Based Oncology Panels: A Joint Consensus Recommendation of the Association for Molecular Pathology and College of American Pathologists.

J Mol Diagn 2017 05 21;19(3):341-365. Epub 2017 Mar 21.

Next-Generation Sequencing Analytical Validation Working Group of the Clinical Practice Committee, Bethesda, Maryland; University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1016/j.jmoldx.2017.01.011DOI Listing
May 2017

A case of acute myeloid leukemia with e6a2 BCR-ABL fusion transcript acquired after progressing from chronic myelomonocytic leukemia.

Leuk Res Rep 2017 31;7:17-19. Epub 2017 Jan 31.

Department of Laboratory Medicine and Pathology Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.lrr.2017.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328719PMC
January 2017

KRAS Mutation Is a Significant Prognostic Factor in Early-stage Lung Adenocarcinoma.

Am J Surg Pathol 2016 12;40(12):1579-1590

*Department of Surgery, Thoracic Service †Department of Pathology §Department of Epidemiology and Biostatistics ∥Department of Medicine, Thoracic Oncology Service, Division of Solid Tumor Oncology ¶Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY ‡Department of Diagnostic Pathology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

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http://dx.doi.org/10.1097/PAS.0000000000000744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106330PMC
December 2016

Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors.

J Clin Oncol 2016 11 30;34(33):4000-4007. Epub 2016 Sep 30.

Aditya Bagrodia, Byron H. Lee, William Lee, Eugene K. Cha, Gopa Iyer, Eugene J. Pietzak, Sizhi Paul Gao, Emily C. Zabor, Irina Ostrovnaya, Samuel D. Kaffenberger, Aijazuddin Syed, Maria E. Arcila, Raju S. Chaganti, Ritika Kundra, Jana Eng, Joseph Hreiki, Michael F. Berger, Dean F. Bajorin, Manjit S. Bains, Nikolaus Schultz, Victor E. Reuter, Joel Sheinfeld, George J. Bosl, Hikmat A. Al-Ahmadie, David B. Solit, Darren R. Feldman, Memorial Sloan Kettering Cancer Center; John P. Sfakianos, Icahn School of Medicine at Mount Sinai; Gopa Iyer, Michael F. Berger, Dean F. Bajorin, Manjit S. Bains, Victor E. Reuter, Joel Sheinfeld, George J. Bosl, Hikmat A. Al-Ahmadie, David B. Solit, Darren R. Feldman, Weill Cornell Medical College; and Vladimir Vacic, Kanika Arora, Dayna M. Oschwald, New York Genome Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2016.68.7798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477828PMC
November 2016

Anakinra as efficacious therapy for 2 cases of intracranial Erdheim-Chester disease.

Blood 2016 10 17;128(14):1896-1898. Epub 2016 Aug 17.

Department of Pediatrics, Hematology-Oncology, University of Utah, Primary Children's Hospital, Salt Lake City, UT.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2016-06-72
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http://dx.doi.org/10.1182/blood-2016-06-725143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054701PMC
October 2016

Outcomes of chemotherapies and HER2 directed therapies in advanced HER2-mutant lung cancers.

Lung Cancer 2016 09 31;99:53-6. Epub 2016 May 31.

Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, NY, USA; Sydney Medical School, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1016/j.lungcan.2016.05.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305295PMC
September 2016

Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels.

J Clin Oncol 2016 06 28;34(18):2141-7. Epub 2016 Mar 28.

Zsofia K. Stadler, Francesca Battaglin, Sumit Middha, Jaclyn F. Hechtman, Christina Tran, Andrea Cercek, Rona Yaeger, Neil H. Segal, Anna M. Varghese, Diane L. Reidy-Lagunes, Nancy E. Kemeny, Erin E. Salo-Mullen, Asad Ashraf, Martin R. Weiser, Julio Garcia-Aguilar, Mark E. Robson, Kenneth Offit, Maria E. Arcila, Michael F. Berger, Jinru Shia, David B. Solit, and Leonard B. Saltz, Memorial Sloan Kettering Cancer Center, New York, NY; and Francesca Battaglin, Veneto Institute of Oncology, Padua, Italy.

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http://dx.doi.org/10.1200/JCO.2015.65.1067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962706PMC
June 2016

Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF.

Mol Cancer Res 2016 Mar 11;14(3):296-301. Epub 2015 Dec 11.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York. Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0392-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972456PMC
March 2016

HER2 Amplification and HER2 Mutation Are Distinct Molecular Targets in Lung Cancers.

J Thorac Oncol 2016 Mar 24;11(3):414-9. Epub 2015 Dec 24.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Molecular Diagnostics Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1016/j.jtho.2015.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698879PMC
March 2016

Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA.

JAMA Oncol 2016 Jan;2(1):104-11

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York6Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering, New York, New York9Weill Cornell Medical College, New York, New York.

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http://dx.doi.org/10.1001/jamaoncol.2015.5208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477989PMC
January 2016

Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials.

Drug Discov Today 2015 Dec 28;20(12):1422-8. Epub 2015 Aug 28.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, NY, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2015.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940024PMC
December 2015

Impact of Concurrent PIK3CA Mutations on Response to EGFR Tyrosine Kinase Inhibition in EGFR-Mutant Lung Cancers and on Prognosis in Oncogene-Driven Lung Adenocarcinomas.

J Thorac Oncol 2015 Dec;10(12):1713-9

*Thoracic Oncology Service, Department of Medicine, †Department of Epidemiology and Biostatistics, ‡Department of Radiology, and §Department of Pathology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864153509
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http://dx.doi.org/10.1097/JTO.0000000000000671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760768PMC
December 2015

HER2 insertion YVMA mutant lung cancer: Long natural history and response to afatinib.

Lung Cancer 2015 Dec 29;90(3):617-9. Epub 2015 Oct 29.

Sydney Medical School, University of Sydney, Sydney, Australia; Department of Medical Oncology, Royal North Shore Hospital, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724317PMC
December 2015

NF1 Mutations Are Common in Desmoplastic Melanoma.

Am J Surg Pathol 2015 Oct;39(10):1357-62

*Department of Pathology †Human Oncology and Pathogenesis Program ‡Department of Medicine, Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://pdfs.journals.lww.com/ajsp/2015/10000/NF1_Mutations_A
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/PAS.0000000000000451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037960PMC
October 2015

Acquired Resistance of EGFR-Mutant Lung Cancer to a T790M-Specific EGFR Inhibitor: Emergence of a Third Mutation (C797S) in the EGFR Tyrosine Kinase Domain.

JAMA Oncol 2015 Oct;1(7):982-4

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York4Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1001/jamaoncol.2015.1066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665629PMC
October 2015