Margaret Taub

Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Bridgeside Point Suite 500, 100 Technology Dr., Pittsburgh, PA, 15219, USA.

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February 2020

Author Correction: Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

Authors:

Michelle Daya Nicholas Rafaels Tonya M Brunetti Sameer Chavan Albert M Levin Aniket Shetty Christopher R Gignoux Meher Preethi Boorgula Genevieve Wojcik Monica Campbell Candelaria Vergara Dara G Torgerson Victor E Ortega Ayo Doumatey Henry Richard Johnston Nathalie Acevedo Maria Ilma Araujo Pedro C Avila Gillian Belbin Eugene Bleecker Carlos Bustamante Luis Caraballo Alvaro Cruz Georgia M Dunston Celeste Eng Mezbah U Faruque Trevor S Ferguson Camila Figueiredo Jean G Ford Weiniu Gan Pierre-Antoine Gourraud Nadia N Hansel Ryan D Hernandez Edwin Francisco Herrera-Paz Silvia Jiménez Eimear E Kenny Jennifer Knight-Madden Rajesh Kumar Leslie A Lange Ethan M Lange Antoine Lizee Pissamai Maul Trevor Maul Alvaro Mayorga Deborah Meyers Dan L Nicolae Timothy D O'Connor Ricardo Riccio Oliveira Christopher O Olopade Olufunmilayo Olopade Zhaohui S Qin Charles Rotimi Nicolas Vince Harold Watson Rainford J Wilks James G Wilson Steven Salzberg Carole Ober Esteban G Burchard L Keoki Williams Terri H Beaty Margaret A Taub Ingo Ruczinski Rasika A Mathias Kathleen C Barnes

Nat Commun 2019 Sep 4;10(1):4082. Epub 2019 Sep 4.

Department of Medicine, University of Colorado Denver, Aurora, CO, 80045, USA.

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September 2019

Replicated methylation changes associated with eczema herpeticum and allergic response.

Clin Epigenetics 2019 08 23;11(1):122. Epub 2019 Aug 23.

University of Colorado, Denver, CO, USA.

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August 2019

Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

Authors:

Michelle Daya Nicholas Rafaels Tonya M Brunetti Sameer Chavan Albert M Levin Aniket Shetty Christopher R Gignoux Meher Preethi Boorgula Genevieve Wojcik Monica Campbell Candelaria Vergara Dara G Torgerson Victor E Ortega Ayo Doumatey Henry Richard Johnston Nathalie Acevedo Maria Ilma Araujo Pedro C Avila Gillian Belbin Eugene Bleecker Carlos Bustamante Luis Caraballo Alvaro Cruz Georgia M Dunston Celeste Eng Mezbah U Faruque Trevor S Ferguson Camila Figueiredo Jean G Ford Weiniu Gan Pierre-Antoine Gourraud Nadia N Hansel Ryan D Hernandez Edwin Francisco Herrera-Paz Silvia Jiménez Eimear E Kenny Jennifer Knight-Madden Rajesh Kumar Leslie A Lange Ethan M Lange Antoine Lizee Pissamai Maul Trevor Maul Alvaro Mayorga Deborah Meyers Dan L Nicolae Timothy D O'Connor Ricardo Riccio Oliveira Christopher O Olopade Olufunmilayo Olopade Zhaohui S Qin Charles Rotimi Nicolas Vince Harold Watson Rainford J Wilks James G Wilson Steven Salzberg Carole Ober Esteban G Burchard L Keoki Williams Terri H Beaty Margaret A Taub Ingo Ruczinski Rasika A Mathias Kathleen C Barnes

Nat Commun 2019 02 20;10(1):880. Epub 2019 Feb 20.

Department of Medicine, University of Colorado Denver, Aurora, CO, 80045, USA.

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February 2019

Author Correction: Assembly of a pan-genome from deep sequencing of 910 humans of African descent.

Nat Genet 2019 02;51(2):364

Center for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA.

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February 2019

Multi-Ancestry Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus.

Gastroenterology 2019 Apr 26;156(5):1496-1507.e7. Epub 2018 Dec 26.

Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland. Electronic address:

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April 2019

Assembly of a pan-genome from deep sequencing of 910 humans of African descent.

Nat Genet 2019 01 19;51(1):30-35. Epub 2018 Nov 19.

Center for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA.

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January 2019

Inferring disease risk genes from sequencing data in multiplex pedigrees through sharing of rare variants.

Authors:

Alexandre Bureau Ferdouse Begum Margaret A Taub Jacqueline B Hetmanski Margaret M Parker Hasan Albacha-Hejazi Alan F Scott Jeffrey C Murray Mary L Marazita Joan E Bailey-Wilson Terri H Beaty Ingo Ruczinski

Genet Epidemiol 2019 02 24;43(1):37-49. Epub 2018 Sep 24.

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

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February 2019

Targeted deep sequencing of the PEAR1 locus for platelet aggregation in European and African American families.

Authors:

Ali R Keramati Lisa R Yanek Kruthika Iyer Margaret A Taub Ingo Ruczinski Diane M Becker Lewis C Becker Nauder Faraday Rasika A Mathias

Platelets 2019 19;30(3):380-386. Epub 2018 Mar 19.

a GeneSTAR Research Program Department of Medicine, Division of General Internal Medicine , Johns Hopkins University School of Medicine , Baltimore , MD , USA.

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April 2019

Analysis of sequence data to identify potential risk variants for oral clefts in multiplex families.

Authors:

Emily R Holzinger Qing Li Margaret M Parker Jacqueline B Hetmanski Mary L Marazita Elisabeth Mangold Kerstin U Ludwig Margaret A Taub Ferdouse Begum Jeffrey C Murray Hasan Albacha-Hejazi Khalid Alqosayer Giath Al-Souki Abdullatiff Albasha Hejazi Alan F Scott Terri H Beaty Joan E Bailey-Wilson

Mol Genet Genomic Med 2017 Sep 9;5(5):570-579. Epub 2017 Aug 9.

Computational and Statistical Genomics BranchNational Human Genome Research InstituteNational Institutes of HealthBaltimoreMaryland.

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September 2017

Identifying Genetic Sources of Phenotypic Heterogeneity in Orofacial Clefts by Targeted Sequencing.

Authors:

Jenna C Carlson Margaret A Taub Eleanor Feingold Terri H Beaty Jeffrey C Murray Mary L Marazita Elizabeth J Leslie

Birth Defects Res 2017 07;109(13):1030-1038

Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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July 2017

Reproducible RNA-seq analysis using recount2.

Authors:

Leonardo Collado-Torres Abhinav Nellore Kai Kammers Shannon E Ellis Margaret A Taub Kasper D Hansen Andrew E Jaffe Ben Langmead Jeffrey T Leek

Nat Biotechnol 2017 04;35(4):319-321

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

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April 2017

Integrity of Induced Pluripotent Stem Cell (iPSC) Derived Megakaryocytes as Assessed by Genetic and Transcriptomic Analysis.

Authors:

Kai Kammers Margaret A Taub Ingo Ruczinski Joshua Martin Lisa R Yanek Alyssa Frazee Yongxing Gao Dixie Hoyle Nauder Faraday Diane M Becker Linzhao Cheng Zack Z Wang Jeff T Leek Lewis C Becker Rasika A Mathias

PLoS One 2017 20;12(1):e0167794. Epub 2017 Jan 20.

The GeneSTAR Research Program, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.

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August 2017

Using genotype array data to compare multi- and single-sample variant calls and improve variant call sets from deep coverage whole-genome sequencing data.

Authors:

Suyash S Shringarpure Rasika A Mathias Ryan D Hernandez Timothy D O'Connor Zachary A Szpiech Raul Torres Francisco M De La Vega Carlos D Bustamante Kathleen C Barnes Margaret A Taub

Bioinformatics 2017 04;33(8):1147-1153

Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, USA.

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April 2017

Evidence for SNP-SNP interaction identified through targeted sequencing of cleft case-parent trios.

Authors:

Yanzi Xiao Margaret A Taub Ingo Ruczinski Ferdouse Begum Jacqueline B Hetmanski Holger Schwender Elizabeth J Leslie Daniel C Koboldt Jeffrey C Murray Mary L Marazita Terri H Beaty

Genet Epidemiol 2017 04 26;41(3):244-250. Epub 2016 Dec 26.

Department of Epidemiology, School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

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April 2017

High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis.

Authors:

David Gomez-Cabrero Malin Almgren Louise K Sjöholm Aase H Hensvold Mikael V Ringh Rakel Tryggvadottir Juha Kere Annika Scheynius Nathalie Acevedo Lovisa Reinius Margaret A Taub Carolina Montano Martin J Aryee Jason I Feinberg Andrew P Feinberg Jesper Tegnér Lars Klareskog Anca I Catrina Tomas J Ekström

Genome Med 2016 11 22;8(1):124. Epub 2016 Nov 22.

Center for Molecular Medicine at Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

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November 2016

A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome.

Authors:

Rasika Ann Mathias Margaret A Taub Christopher R Gignoux Wenqing Fu Shaila Musharoff Timothy D O'Connor Candelaria Vergara Dara G Torgerson Maria Pino-Yanes Suyash S Shringarpure Lili Huang Nicholas Rafaels Meher Preethi Boorgula Henry Richard Johnston Victor E Ortega Albert M Levin Wei Song Raul Torres Badri Padhukasahasram Celeste Eng Delmy-Aracely Mejia-Mejia Trevor Ferguson Zhaohui S Qin Alan F Scott Maria Yazdanbakhsh James G Wilson Javier Marrugo Leslie A Lange Rajesh Kumar Pedro C Avila L Keoki Williams Harold Watson Lorraine B Ware Christopher Olopade Olufunmilayo Olopade Ricardo Oliveira Carole Ober Dan L Nicolae Deborah Meyers Alvaro Mayorga Jennifer Knight-Madden Tina Hartert Nadia N Hansel Marilyn G Foreman Jean G Ford Mezbah U Faruque Georgia M Dunston Luis Caraballo Esteban G Burchard Eugene Bleecker Maria Ilma Araujo Edwin Francisco Herrera-Paz Kimberly Gietzen Wendy E Grus Michael Bamshad Carlos D Bustamante Eimear E Kenny Ryan D Hernandez Terri H Beaty Ingo Ruczinski Joshua Akey Kathleen C Barnes

Nat Commun 2016 10 11;7:12522. Epub 2016 Oct 11.

Department of Medicine, Johns Hopkins University, Baltimore, Maryland 21224, USA.

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October 2016

Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry.

Authors:

Michael D Kessler Laura Yerges-Armstrong Margaret A Taub Amol C Shetty Kristin Maloney Linda Jo Bone Jeng Ingo Ruczinski Albert M Levin L Keoki Williams Terri H Beaty Rasika A Mathias Kathleen C Barnes Timothy D O'Connor

Nat Commun 2016 10 11;7:12521. Epub 2016 Oct 11.

Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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October 2016

Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study.

JAMA Psychiatry 2016 05;73(5):506-14

Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, Maryland5Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland14Departments of Medicine and Biomedical Engineering, Johns Hopkins U.

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May 2016

Identification and functional studies of regulatory variants responsible for the association of with a delusion phenotype in schizophrenia.

Authors:

Mariela Zeledón Nicole Eckart Margaret Taub Hilary Vernon Megan Szymanksi Ruihua Wang Pei-Lung Chen Gerry Nestadt John A McGrath Akira Sawa Ann E Pulver Dimitrios Avramopoulos David Valle

Mol Neuropsychiatry 2015 May 27;1(1):36-46. Epub 2015 Feb 27.

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.

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May 2015

Identification of Rare Variants in ATP8B4 as a Risk Factor for Systemic Sclerosis by Whole-Exome Sequencing.

Authors:

Li Gao Mary J Emond Tin Louie Chris Cheadle Alan E Berger Nicholas Rafaels Candelaria Vergara Yoonhee Kim Margaret A Taub Ingo Ruczinski Stephen C Mathai Stephen S Rich Deborah A Nickerson Laura K Hummers Michael J Bamshad Paul M Hassoun Rasika A Mathias Kathleen C Barnes

Arthritis Rheumatol 2016 Jan;68(1):191-200

Johns Hopkins University, Baltimore, Maryland.

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January 2016

Identification of functional variants for cleft lip with or without cleft palate in or near PAX7, FGFR2, and NOG by targeted sequencing of GWAS loci.

Am J Hum Genet 2015 Mar 19;96(3):397-411. Epub 2015 Feb 19.

Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

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March 2015

Analytic power and sample size calculation for the genotypic transmission/disequilibrium test in case-parent trio studies.

Authors:

Christoph Neumann Margaret A Taub Samuel G Younkin Terri H Beaty Ingo Ruczinski Holger Schwender

Biom J 2014 Nov 14;56(6):1076-92. Epub 2014 Aug 14.

Faculty of Statistics, TU Dortmund University, 44221, Dortmund, Germany.

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November 2014

Detecting disease variants in case-parent trio studies using the bioconductor software package trio.

Authors:

Holger Schwender Qing Li Christoph Neumann Margaret A Taub Samuel G Younkin Philipp Berger Robert B Scharpf Terri H Beaty Ingo Ruczinski

Genet Epidemiol 2014 Sep 21;38(6):516-22. Epub 2014 Jul 21.

Mathematical Institute, Heinrich Heine University, Düsseldorf, Germany.

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September 2014

Whole exome sequencing of distant relatives in multiplex families implicates rare variants in candidate genes for oral clefts.

Genetics 2014 Jul 2;197(3):1039-44. Epub 2014 May 2.

Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205

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July 2014

Evidence of gene-environment interaction for two genes on chromosome 4 and environmental tobacco smoke in controlling the risk of nonsyndromic cleft palate.

PLoS One 2014 6;9(2):e88088. Epub 2014 Feb 6.

Johns Hopkins University, School of Public Health, Baltimore, Maryland, United States of America.

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January 2015

On multi-marker tests for association in case-control studies.

Authors:

Margaret A Taub Holger R Schwender Samuel G Younkin Thomas A Louis Ingo Ruczinski

Front Genet 2013 16;4:252. Epub 2013 Dec 16.

Department of Biostatistics, Johns Hopkins University Baltimore, MD, USA.

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December 2013

Measuring cell-type specific differential methylation in human brain tissue.

Authors:

Carolina M Montaño Rafael A Irizarry Walter E Kaufmann Konrad Talbot Raquel E Gur Andrew P Feinberg Margaret A Taub

Genome Biol 2013 Aug 30;14(8):R94. Epub 2013 Aug 30.

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August 2013

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis.

Authors:

Yun Liu Martin J Aryee Leonid Padyukov M Daniele Fallin Espen Hesselberg Arni Runarsson Lovisa Reinius Nathalie Acevedo Margaret Taub Marcus Ronninger Klementy Shchetynsky Annika Scheynius Juha Kere Lars Alfredsson Lars Klareskog Tomas J Ekström Andrew P Feinberg

Nat Biotechnol 2013 Feb 20;31(2):142-7. Epub 2013 Jan 20.

Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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February 2013

A statistical approach to selecting and confirming validation targets in -omics experiments.

Authors:

Jeffrey T Leek Margaret A Taub Jason L Rasgon

BMC Bioinformatics 2012 Jun 27;13:150. Epub 2012 Jun 27.

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205-2179, USA.

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June 2012

Incorporating genotype uncertainties into the genotypic TDT for main effects and gene-environment interactions.

Authors:

Margaret A Taub Holger Schwender Terri H Beaty Thomas A Louis Ingo Ruczinski

Genet Epidemiol 2012 Apr;36(3):225-34

Department of Biostatistics, Johns Hopkins University, 615 N.Wolfe Street, Baltimore, MD 21205-2179, USA.

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April 2012

Examining markers in 8q24 to explain differences in evidence for association with cleft lip with/without cleft palate between Asians and Europeans.

Genet Epidemiol 2012 May 16;36(4):392-9. Epub 2012 Apr 16.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.

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May 2012

Rapid testing of SNPs and gene-environment interactions in case-parent trio data based on exact analytic parameter estimation.

Authors:

Holger Schwender Margaret A Taub Terri H Beaty Mary L Marazita Ingo Ruczinski

Biometrics 2012 Sep 7;68(3):766-73. Epub 2011 Dec 7.

TU Dortmund University, 44221 Dortmund, Germany.

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September 2012

Cooperation between referees and authors increases peer review accuracy.

Authors:

Jeffrey T Leek Margaret A Taub Fernando J Pineda

PLoS One 2011 9;6(11):e26895. Epub 2011 Nov 9.

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

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April 2012

Effective detection of rare variants in pooled DNA samples using Cross-pool tailcurve analysis.

Authors:

Tejasvi S Niranjan Abby Adamczyk Héctor Corrada Bravo Margaret A Taub Sarah J Wheelan Rafael Irizarry Tao Wang

Genome Biol 2011 Sep 28;12(9):R93. Epub 2011 Sep 28.

McKusick-Nathans Institute of Genetic Medicine and Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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September 2011

Overcoming bias and systematic errors in next generation sequencing data.

Authors:

Margaret A Taub Hector Corrada Bravo Rafael A Irizarry

Genome Med 2010 Dec 10;2(12):87. Epub 2010 Dec 10.

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, E3527, Baltimore, MD 21205, USA.

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December 2010

Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region.

Authors:

Shweta Choudhry Margaret Taub Rui Mei José Rodriguez-Santana William Rodriguez-Cintron Mark D Shriver Elad Ziv Neil J Risch Esteban González Burchard

Hum Genet 2008 Jun 10;123(5):455-68. Epub 2008 Apr 10.

Institute for Human Genetics, University of California, San Francisco, CA, USA.

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June 2008

A whole genome long-range haplotype (WGLRH) test for detecting imprints of positive selection in human populations.

Authors:

Chun Zhang Dione K Bailey Tarif Awad Guoying Liu Guoliang Xing Manqiu Cao Venu Valmeekam Jacques Retief Hajime Matsuzaki Margaret Taub Mark Seielstad Giulia C Kennedy

Bioinformatics 2006 Sep 15;22(17):2122-8. Epub 2006 Jul 15.

Affymetrix Inc, 3380 Central Expressway, Santa Clara, CA 95051, USA.

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September 2006

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