Publications by authors named "Margaret L MacMillan"

100Publications

Risk Factors for Graft-versus-Host Disease in Haploidentical Hematopoietic Cell Transplantation Using Post-Transplant Cyclophosphamide.

Biol Blood Marrow Transplant 2020 Aug 17;26(8):1459-1468. Epub 2020 May 17.

Blood & Marrow Transplant Program, Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2020.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391266PMC
August 2020

Hematopoietic Stem Cell Transplantation for Shwachman-Diamond Syndrome.

Biol Blood Marrow Transplant 2020 Aug 16;26(8):1446-1451. Epub 2020 May 16.

Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2020.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371524PMC
August 2020

Author Correction: Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity.

Sci Rep 2020 Feb 19;10(1):3317. Epub 2020 Feb 19.

Molecular Pathogenesis Program, Skirball Institute of Biomolecular Medicine, Department of Pathology, New York University School of Medicine, New York, NY, 10016, USA.

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http://dx.doi.org/10.1038/s41598-020-60485-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031276PMC
February 2020

Pediatric acute GVHD: clinical phenotype and response to upfront steroids.

Bone Marrow Transplant 2020 01 2;55(1):165-171. Epub 2019 Sep 2.

Blood and Marrow Transplant Program, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN, USA.

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http://www.nature.com/articles/s41409-019-0651-9
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http://dx.doi.org/10.1038/s41409-019-0651-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940525PMC
January 2020

Outcomes and Predictors of Response in Steroid-Refractory Acute Graft-versus-Host Disease.

Biol Blood Marrow Transplant 2019 11 17;25(11):2297-2302. Epub 2019 Jul 17.

Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1016/j.bbmt.2019.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861661PMC
November 2019

Validation of Minnesota acute graft--host disease Risk Score.

Haematologica 2020 31;105(2):519-524. Epub 2020 Jan 31.

Blood and Marrow Transplant Program, University of Minnesota Medical School, Minneapolis, MN.

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http://dx.doi.org/10.3324/haematol.2019.220970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012472PMC
January 2020

Pretransplant Serum Citrulline Predicts Acute Graft-versus-Host Disease.

Biol Blood Marrow Transplant 2018 11 7;24(11):2190-2196. Epub 2018 Jul 7.

Division of Hematology, Oncology, and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.

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https://linkinghub.elsevier.com/retrieve/pii/S10838791183038
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http://dx.doi.org/10.1016/j.bbmt.2018.06.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251308PMC
November 2018

Elevations in serum alpha fetoprotein levels in patients with Fanconi anaemia.

Br J Haematol 2019 03 20;184(6):1032-1035. Epub 2018 Apr 20.

Blood and Marrow Transplant Program, Masonic Cancer Center, Minneapolis, MN, USA.

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http://dx.doi.org/10.1111/bjh.15223DOI Listing
March 2019

Comparable Outcomes after HLA-Matched Sibling and Alternative Donor Hematopoietic Cell Transplantation for Children with Fanconi Anemia and Severe Aplastic Anemia.

Biol Blood Marrow Transplant 2018 04 2;24(4):765-771. Epub 2017 Dec 2.

Division of Blood and Marrow Transplant, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1016/j.bbmt.2017.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915968PMC
April 2018

Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity.

Sci Rep 2017 06 26;7(1):4258. Epub 2017 Jun 26.

Molecular Pathogenesis Program, Skirball Institute of Biomolecular Medicine, Department of Pathology, New York University School of Medicine, New York, NY, 10016, USA.

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http://dx.doi.org/10.1038/s41598-017-04053-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484704PMC
June 2017

Fanconi anemia: correlating central nervous system malformations and genetic complementation groups.

Pediatr Radiol 2017 Jun 10;47(7):868-876. Epub 2017 Mar 10.

Department of Radiology, Neuroradiology Section, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1007/s00247-017-3817-xDOI Listing
June 2017

Hematopoietic cell transplantation in Fanconi anemia: current evidence, challenges and recommendations.

Expert Rev Hematol 2017 Jan 21;10(1):81-97. Epub 2016 Dec 21.

a Division of Pediatric Blood and Marrow Transplantation, Department of Pediatrics , University of Minnesota Medical School , Minneapolis , MN , USA.

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http://dx.doi.org/10.1080/17474086.2016.1268048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089510PMC
January 2017

Phenotypic variability in patients with Fanconi anemia and biallelic FANCF mutations.

Am J Med Genet A 2017 Jan 7;173(1):260-263. Epub 2016 Oct 7.

Department of Pediatrics, Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1002/ajmg.a.37998DOI Listing
January 2017

CRISPR/Cas9 Targeted Gene Editing and Cellular Engineering in Fanconi Anemia.

Stem Cells Dev 2016 10 18;25(20):1591-1603. Epub 2016 Aug 18.

University of Minnesota Twin Cities, 5635, Pediatrics, Minneapolis, Minnesota, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035838PMC
http://dx.doi.org/10.1089/scd.2016.0149DOI Listing
October 2016

Endocrinopathies, Bone Health, and Insulin Resistance in Patients with Fanconi Anemia after Hematopoietic Cell Transplantation.

Biol Blood Marrow Transplant 2016 08 12;22(8):1487-1492. Epub 2016 May 12.

Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545800PMC
August 2016

Late Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2016 May 29;22(5):879-83. Epub 2015 Dec 29.

Division of Hematology, Oncology and Transplantation, University of Minnesota Medical School, Minneapolis, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2015.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922492PMC
May 2016

Bone mineral density in children with fanconi anemia after hematopoietic cell transplantation.

Biol Blood Marrow Transplant 2015 May 13;21(5):894-9. Epub 2015 Jan 13.

Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1016/j.bbmt.2015.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408223PMC
May 2015

A refined risk score for acute graft-versus-host disease that predicts response to initial therapy, survival, and transplant-related mortality.

Biol Blood Marrow Transplant 2015 Apr 10;21(4):761-7. Epub 2015 Jan 10.

Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota; Blood and Marrow Transplant Clinical Trials Network GVHD Study Committee, Milwaukee, Wisconsin; Department of Medicine, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1016/j.bbmt.2015.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359643PMC
April 2015

Growth hormone treatment of patients with Fanconi anemia after hematopoietic cell transplantation.

Pediatr Blood Cancer 2014 Jun 24;61(6):1142-3. Epub 2013 Dec 24.

Department of Pediatrics, Division of Pediatric Endocrinology, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1002/pbc.24910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989390PMC
June 2014

Haematopoietic cell transplantation for acute leukaemia and advanced myelodysplastic syndrome in Fanconi anaemia.

Br J Haematol 2014 Feb 30;164(3):384-95. Epub 2013 Oct 30.

Blood and Marrow Transplant Program, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.

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http://doi.wiley.com/10.1111/bjh.12634
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http://dx.doi.org/10.1111/bjh.12634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060801PMC
February 2014

More than 10 years after the first 'savior siblings': parental experiences surrounding preimplantation genetic diagnosis.

J Genet Couns 2013 Oct 28;22(5):594-602. Epub 2013 Apr 28.

Department of Genetic Counseling, University of Minnesota, 420 Delaware Street, SE, MMC 484, Minneapolis, MN, 55455, USA,

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http://dx.doi.org/10.1007/s10897-013-9591-5DOI Listing
October 2013

Early hematopoietic stem cell transplant is associated with favorable outcomes in children with MDS.

Pediatr Blood Cancer 2013 Apr 14;60(4):705-10. Epub 2012 Nov 14.

Division of Pediatric Blood and Marrow Transplantation, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1002/pbc.24390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668778PMC
April 2013

Intractable hemorrhagic cystitis after hematopoietic stem cell tranplantation--is there a role for early urinary diversion in children?

J Urol 2012 Jul 15;188(1):242-6. Epub 2012 May 15.

Division of Urology, University of Minnesota Amplatz Children's Hospital, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1016/j.juro.2012.03.020DOI Listing
July 2012

What predicts high risk acute graft-versus-host disease (GVHD) at onset?: identification of those at highest risk by a novel acute GVHD risk score.

Br J Haematol 2012 Jun 6;157(6):732-41. Epub 2012 Apr 6.

Blood and Marrow Transplant Program, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2012.09114.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654854PMC
June 2012

Formation of cyclophosphamide specific DNA adducts in hematological diseases.

Pediatr Blood Cancer 2012 May 25;58(5):708-14. Epub 2011 Jul 25.

Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://doi.wiley.com/10.1002/pbc.23254
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http://dx.doi.org/10.1002/pbc.23254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204332PMC
May 2012

Cellular therapy for fanconi anemia: the past, present, and future.

Biol Blood Marrow Transplant 2011 Jan;17(1 Suppl):S109-14

The Division of Pediatric Hematology, Oncology, and Blood and Marrow Transplantation, University of Minnesota Blood and Marrow Transplant Program, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1016/j.bbmt.2010.11.027DOI Listing
January 2011

The best endpoint for acute GVHD treatment trials.

Blood 2010 Jul 13;115(26):5412-7. Epub 2010 Apr 13.

Blood and Marrow Transplant Program, University of Minnesota Medical School, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1182/blood-2009-12-258442DOI Listing
July 2010

Management of acute graft-versus-host disease in children.

Pediatr Clin North Am 2010 Feb;57(1):273-95

Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Mailstop D5-290, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1016/j.pcl.2009.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227683PMC
February 2010

Haematopoeitic cell transplantation for Fanconi anaemia - when and how?

Br J Haematol 2010 Apr 5;149(1):14-21. Epub 2010 Feb 5.

Department of Pediatrics, University of Minnesota Medical School, Minneapolis, 55455, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2010.08078.xDOI Listing
April 2010

Transplant outcomes in bone marrow failure syndromes and hemoglobinopathies.

Semin Hematol 2010 Jan;47(1):37-45

Division of Pediatric Hematology, Oncology, and Blood and Marrow Transplantation, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1053/j.seminhematol.2009.10.004DOI Listing
January 2010

Diagnosis of myelodysplastic syndrome among a cohort of 119 patients with fanconi anemia: morphologic and cytogenetic characteristics.

Am J Clin Pathol 2010 Jan;133(1):92-100

Department of Laboratory Medicine and Pathology, University of Minnesota Masonic Cancer Center, University of Minnesota Medical School, Minneapolis 55455, USA.

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https://academic.oup.com/ajcp/article-lookup/doi/10.1309/AJC
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http://dx.doi.org/10.1309/AJCP7W9VMJENZOVGDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467447PMC
January 2010

Costs of pediatric allogeneic hematopoietic-cell transplantation.

Pediatr Blood Cancer 2010 Jan;54(1):138-43

Adult Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, MN 55455, USA.

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http://doi.wiley.com/10.1002/pbc.22250
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http://dx.doi.org/10.1002/pbc.22250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111794PMC
January 2010

Where is the start line?

Blood 2009 Mar;113(13):2872-3

University of Minnesota, USA.

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http://dx.doi.org/10.1182/blood-2008-12-192807DOI Listing
March 2009

Twenty years of unrelated donor bone marrow transplantation for pediatric acute leukemia facilitated by the National Marrow Donor Program.

Biol Blood Marrow Transplant 2008 Sep;14(9 Suppl):16-22

Division of Pediatric Hematology, Oncology, and Blood and Marrow Transplantation, University of Minnesota Blood and Marrow Transplant Program, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1016/j.bbmt.2008.05.019DOI Listing
September 2008

Long-term results of autologous stem cell transplantation for primary refractory or relapsed Hodgkin's lymphoma.

Biol Blood Marrow Transplant 2006 Oct;12(10):1065-72

Blood and Marrow Transplant Program, Divisions of Medical and Pediatric Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/j.bbmt.2006.06.006DOI Listing
October 2006

Unrelated donor bone marrow transplantation for the treatment of Fanconi anemia.

Blood 2007 Mar 12;109(5):2256-62. Epub 2006 Oct 12.

Division of Pediatric Hematology, Oncology, and Blood and Marrow Transplantation, University of Minnesota Blood and Marrow Transplant Program, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1182/blood-2006-07-036657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1801062PMC
March 2007

Successful engraftment without radiation after fludarabine-based regimen in Fanconi anemia patients undergoing genotypically identical donor hematopoietic cell transplantation.

Pediatr Blood Cancer 2006 May;46(5):630-6

Department of Pediatrics, Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1002/pbc.20538DOI Listing
May 2006

Serious infections after unrelated donor transplantation in 136 children: impact of stem cell source.

Biol Blood Marrow Transplant 2005 May;11(5):362-70

Division of Medical Hematology, Oncology, and Transplantation, University of Minnesota Blood and Marrow Transplant Program, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1016/j.bbmt.2005.02.004DOI Listing
May 2005

Hematopoietic cell transplantation for congenital bone marrow failure.

Curr Opin Oncol 2005 Mar;17(2):106-13

Division of Pediatric Hematology, Oncology, and Blood and Marrow Transplantation, University of Minnesota Medical School, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1097/01.cco.0000152977.55175.5bDOI Listing
March 2005

Long-term follow-up after autologous hematopoietic stem cell transplantation for low-grade non-Hodgkin lymphoma.

Biol Blood Marrow Transplant 2005 Feb;11(2):129-35

Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/j.bbmt.2004.11.017DOI Listing
February 2005

Patient interleukin-18 GCG haplotype associates with improved survival and decreased transplant-related mortality after unrelated-donor bone marrow transplantation.

Br J Haematol 2004 Sep;126(5):704-10

Department of Pathology and Microbiology, University of Bristol, Homeopathic Hospital Site, Cotham, University Walk, Bristol BS8 1TD, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2004.05128.xDOI Listing
September 2004

Germline mutations in BRCA2: shared genetic susceptibility to breast cancer, early onset leukemia, and Fanconi anemia.

Blood 2004 Apr 8;103(8):3226-9. Epub 2004 Jan 8.

Division of Pediatric Hematology, Oncology, and Blood Marrow Transplantation, University of Minnesota Medical School, Minneapolis, MN, USA.

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http://dx.doi.org/10.1182/blood-2003-09-3138DOI Listing
April 2004

Fatal hemorrhage from androgen-related hepatic adenoma after hematopoietic cell transplantation.

J Pediatr Hematol Oncol 2004 Jan;26(1):16-8

Bone Marrow Transplant Program and Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.

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http://pdfs.journals.lww.com/jpho-online/2004/01000/Fatal_He
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http://dx.doi.org/10.1097/00043426-200401000-00006DOI Listing
January 2004

High-producer interleukin-2 genotype increases risk for acute graft-versus-host disease after unrelated donor bone marrow transplantation.

Transplantation 2003 Dec;76(12):1758-62

Department of Pediatrics, University of Minnesota, MMC 484, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1097/01.TP.0000095899.54052.89DOI Listing
December 2003

Successful hematopoietic stem cell transplantation for Fanconi anemia from an unaffected HLA-genotype-identical sibling selected using preimplantation genetic diagnosis.

Blood 2004 Feb 22;103(3):1147-51. Epub 2003 Sep 22.

Department of Blood and Marrow Transplantation and the Center for Bioethics, University of Minnesota, Minneapolis, MN 55455, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2003-02-05
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http://dx.doi.org/10.1182/blood-2003-02-0587DOI Listing
February 2004

Interleukin-1 genotype and outcome of unrelated donor bone marrow transplantation.

Br J Haematol 2003 May;121(4):597-604

Pediatrics Department, Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1046/j.1365-2141.2003.04314.xDOI Listing
May 2003

Chronic graft-versus-host disease: a prospective cohort study.

Biol Blood Marrow Transplant 2003 Jan;9(1):38-45

Department of Medicine, Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10838791020000
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http://dx.doi.org/10.1053/bbmt.2003.50003DOI Listing
January 2003

Fluconazole to prevent yeast infections in bone marrow transplantation patients: a randomized trial of high versus reduced dose, and determination of the value of maintenance therapy.

Am J Med 2002 Apr;112(5):369-79

Department of Pediatrics, University of Minnesota, MMC 484, 420 Delaware Street Southeast, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/s0002-9343(01)01127-5DOI Listing
April 2002

Early antithymocyte globulin therapy improves survival in patients with steroid-resistant acute graft-versus-host disease.

Biol Blood Marrow Transplant 2002 ;8(1):40-6

Department of Pediatrics, Blood and Marrow Transplant Program, University of Minnesota, Minneapolis 55455, USA.

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http://dx.doi.org/10.1053/bbmt.2002.v8.pm11858189DOI Listing
July 2003