Margaret Ho

Margaret Ho

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Margaret Ho

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α-Synuclein Trafficking in Parkinson's Disease: Insights From Fly and Mouse Models.

ASN Neuro 2018 Jan-Dec;10:1759091418812587

1 School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

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http://dx.doi.org/10.1177/1759091418812587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259071PMC
July 2019

Traffic jam regulates the function of the ovarian germline stem cell progeny differentiation niche during pre-adult stage in Drosophila.

Sci Rep 2019 Jul 12;9(1):10124. Epub 2019 Jul 12.

State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.

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http://dx.doi.org/10.1038/s41598-019-45317-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626045PMC
July 2019

Wingless modulates activator protein-1-mediated tumor invasion.

Oncogene 2019 May 25;38(20):3871-3885. Epub 2019 Jan 25.

Institute of Intervention Vessel, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai, 200092, China.

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http://www.nature.com/articles/s41388-018-0629-x
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http://dx.doi.org/10.1038/s41388-018-0629-xDOI Listing
May 2019

A hyaluronan/methylcellulose-based hydrogel for local cell and biomolecule delivery to the central nervous system.

Brain Res Bull 2019 May 18;148:46-54. Epub 2019 Mar 18.

Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Canada; Donnelly Centre for Cellular & Biomolecular Research, University of Toronto, Toronto, Canada; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada; Department of Chemistry, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.brainresbull.2019.03.005DOI Listing
May 2019

Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay.

Neuron 2019 May 10;102(4):843-857.e4. Epub 2019 Apr 10.

Department of Neuroscience, Washington University in St. Louis, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.03.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533154PMC
May 2019

Editorial: Glia in Health and Disease.

Front Mol Neurosci 2019 19;12:63. Epub 2019 Mar 19.

Department of Neurobiology, The University of Alabama at Birmingham, Birmingham, AL, United States.

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http://dx.doi.org/10.3389/fnmol.2019.00063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436194PMC
March 2019

Characterization and complete genome analysis of the surfactin-producing, plant-protecting bacterium Bacillus velezensis 9D-6.

BMC Microbiol 2019 Jan 8;19(1). Epub 2019 Jan 8.

Department of Microbiology & Immunology, Schulich School of Medicine & Dentistry, Dental Science Building Rm. 3014, University of Western Ontario, London, ON, N6A 5C1, Canada.

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http://dx.doi.org/10.1186/s12866-018-1380-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325804PMC
January 2019

A Shared Neural Node for Multiple Innate Behaviors in Drosophila.

Authors:
Margaret S Ho

Neurosci Bull 2018 Dec 9;34(6):1103-1104. Epub 2018 Nov 9.

School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.

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http://link.springer.com/10.1007/s12264-018-0311-x
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http://dx.doi.org/10.1007/s12264-018-0311-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246851PMC
December 2018

The TEA domain family transcription factor TEAD4 represses murine adipogenesis by recruiting the cofactors VGLL4 and CtBP2 into a transcriptional complex.

J Biol Chem 2018 11 12;293(44):17119-17134. Epub 2018 Sep 12.

From the State Key Laboratory of Cell Biology, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China and

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http://dx.doi.org/10.1074/jbc.RA118.003608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222106PMC
November 2018

A Genetic Toolkit for Dissecting Dopamine Circuit Function in Drosophila.

Cell Rep 2018 Apr;23(2):652-665

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183042
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http://dx.doi.org/10.1016/j.celrep.2018.03.068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962273PMC
April 2018

Genome-wide discovery of active regulatory elements and transcription factor footprints in using DNase-seq.

Genome Res 2017 12 26;27(12):2108-2119. Epub 2017 Oct 26.

Division of Biology and Bioengineering, Howard Hughes Medical Institute, California Institute of Technology, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1101/gr.223735.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741056PMC
December 2017

An Automated Rapid Iterative Negative Geotaxis Assay for Analyzing Adult Climbing Behavior in a Drosophila Model of Neurodegeneration.

J Vis Exp 2017 09 12(127). Epub 2017 Sep 12.

Research Center for Translational Medicine, Tongji University School of Medicine; Key Laboratory of Arrhythmias of the Ministry of Education of China, Shanghai East Hospital, Tongji University School of Medicine; Department of Anatomy and Neurobiology, Tongji University School of Medicine;

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https://www.jove.com/video/56507/an-automated-rapid-iterativ
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http://dx.doi.org/10.3791/56507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752225PMC
September 2017

Erratum for Ho et al., "Complete Genome Sequence of CA16, a Bacterium Capable of Degrading Diesel and Lignin".

Genome Announc 2017 Aug 3;5(31). Epub 2017 Aug 3.

Department of Microbiology and Immunology, Western University, London, Ontario, Canada.

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http://dx.doi.org/10.1128/genomeA.00808-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543656PMC
August 2017

Complete Genome Sequence of CA16, a Bacterium Capable of Degrading Diesel and Lignin.

Genome Announc 2017 Jun 15;5(24). Epub 2017 Jun 15.

Department of Microbiology and Immunology, Western University, London, Ontario, Canada

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http://dx.doi.org/10.1128/genomeA.00494-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473259PMC
June 2017

Prevention of medulla neuron dedifferentiation by Nerfin-1 requires inhibition of Notch activity.

Development 2017 04 27;144(8):1510-1517. Epub 2017 Feb 27.

State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, People's Republic of China

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http://dx.doi.org/10.1242/dev.141341DOI Listing
April 2017

Molecular Chaperone Calnexin Regulates the Function of Sodium Channel Paralytic.

Front Mol Neurosci 2017 7;10:57. Epub 2017 Mar 7.

Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Department of Anatomy and Neurobiology, Tongji University School of MedicineShanghai, China.

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http://dx.doi.org/10.3389/fnmol.2017.00057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339336PMC
March 2017

Neuroglial Crosstalk by Mitochondria.

Authors:
Margaret S Ho

Neurosci Bull 2017 Feb 12;33(1):111-112. Epub 2016 Oct 12.

Research Center for Translational Medicine, Shanghai East Hospital, No. 150 Jimo Road, Shanghai, 200120, China.

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http://dx.doi.org/10.1007/s12264-016-0072-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567542PMC
February 2017

The hypoparathyroidism-associated mutation in Drosophila Gcm compromises protein stability and glial cell formation.

Sci Rep 2017 01 4;7:39856. Epub 2017 Jan 4.

Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, No. 150 Jimo Road, Shanghai 200120, China.

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http://www.nature.com/articles/srep39856
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http://dx.doi.org/10.1038/srep39856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209662PMC
January 2017

Drosophila ubiquitin E3 ligase dSmurf is required for synapse remodeling and axon pruning by glia.

J Genet Genomics 2017 01 11;44(1):67-70. Epub 2016 Nov 11.

Research Center for Translational Medicine, Shanghai 200092, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, Shanghai East Hospital, No. 150 Jimo Road, Shanghai 200092, China; Department of Anatomy and Neurobiology, 1239 Siping Road, Tongji University School of Medicine, Shanghai 200092, China. Electronic address:

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http://dx.doi.org/10.1016/j.jgg.2016.10.007DOI Listing
January 2017

Auxilin Underlies Progressive Locomotor Deficits and Dopaminergic Neuron Loss in a Drosophila Model of Parkinson's Disease.

Cell Rep 2017 01;18(5):1132-1143

Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, No. 150 Jimo Road, Shanghai 200120, China; Key Laboratory of Arrhythmias, Ministry of Education of China, Shanghai East Hospital, Tongji University School of Medicine, No. 150 Jimo Road, Shanghai 200120, China; Department of Anatomy and Neurobiology, 1239 Siping Road, Tongji University School of Medicine, Shanghai 200092, China. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.01.005DOI Listing
January 2017

Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded.

Cell Discov 2016 23;2:15047. Epub 2016 Feb 23.

State Key Laboratory of Cell Biology, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

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http://dx.doi.org/10.1038/celldisc.2015.47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860957PMC
July 2016

Analysis of Glial Distribution in Drosophila Adult Brains.

Neurosci Bull 2016 Apr 25;32(2):162-70. Epub 2016 Jan 25.

Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, No. 150 Jimo Road, Shanghai, 200092, China.

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http://dx.doi.org/10.1007/s12264-016-0014-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563736PMC
April 2016

Suppressor of Deltex mediates Pez degradation and modulates Drosophila midgut homeostasis.

Nat Commun 2015 Mar 27;6:6607. Epub 2015 Mar 27.

State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1038/ncomms7607DOI Listing
March 2015

Neurodevelopment and degeneration.

Authors:
Margaret S Ho

Neurosci Bull 2014 Aug;30(4):539-41

Department of Anatomy and Neurobiology, School of Medicine, Tongji University, Shanghai, 200092, China,

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http://link.springer.com/10.1007/s12264-014-1455-3
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http://dx.doi.org/10.1007/s12264-014-1455-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562633PMC
August 2014

LRP6 dimerization through its LDLR domain is required for robust canonical Wnt pathway activation.

Cell Signal 2014 May 8;26(5):1068-74. Epub 2014 Jan 8.

Clinical and Translational Research Center Shanghai East Hospital, Key Laboratory of Arrhythmias of Ministry of Education, Shanghai, China; Tongji University School of Medicine, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2013.12.020DOI Listing
May 2014

Analysis of microglial migration by a micropipette assay.

Nat Protoc 2014 Feb 30;9(2):491-500. Epub 2014 Jan 30.

Department of Neurobiology, The Key Laboratory of Medical Neurobiology, The Ministry of Health of China, Zhejiang Provincial Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, China.

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http://dx.doi.org/10.1038/nprot.2014.015DOI Listing
February 2014

Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling.

Elife 2013 Oct 15;2:e00999. Epub 2013 Oct 15.

State Key Laboratory of Cell Biology , Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.

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https://elifesciences.org/articles/00999
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http://dx.doi.org/10.7554/eLife.00999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796317PMC
October 2013

Gcm proteins function in the developing nervous system.

Dev Biol 2012 Oct 24;370(1):63-70. Epub 2012 Jul 24.

Department of Nuclear Medicine, Shanghai Tenth Hospital, Tongji University, Shanghai 200072, China.

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http://dx.doi.org/10.1016/j.ydbio.2012.07.018DOI Listing
October 2012

A modular library of small molecule signals regulates social behaviors in Caenorhabditis elegans.

PLoS Biol 2012 Jan 10;10(1):e1001237. Epub 2012 Jan 10.

Howard Hughes Medical Institute and Division of Biology, California Institute of Technology, Pasadena, California, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.1001237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254649PMC
January 2012

CSN-mediated deneddylation differentially modulates Ci(155) proteolysis to promote Hedgehog signalling responses.

Nat Commun 2011 Feb 8;2:182. Epub 2011 Feb 8.

Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.

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http://dx.doi.org/10.1038/ncomms1185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105314PMC
February 2011

Between transcription and translation: Re-defining RNA and regulation.

Fly (Austin) 2008 May-Jun;2(3):152-5. Epub 2008 May 26.

Biology Department, Harvey Mudd College, Claremont, California, USA.

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http://dx.doi.org/10.4161/fly.6382DOI Listing
December 2010

A nationwide survey of past hepatitis A infections among Canadian adults.

Vaccine 2010 Jul 15;28(32):5174-8. Epub 2010 Jun 15.

University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.vaccine.2010.05.076DOI Listing
July 2010

Dissecting the regulatory switches of development: lessons from enhancer evolution in Drosophila.

Development 2010 Jan;137(1):5-13

Biology Department, Harvey Mudd College, 301 Platt Boulevard, Claremont, CA 91711, USA.

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http://dx.doi.org/10.1242/dev.036160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796927PMC
January 2010

Non-genic transcription at the Drosophila bithorax complex functional activity of the dark matter of the genome.

Int J Dev Biol 2009 ;53(4):459-68

Biology Department, Harvey Mudd College, Claremont, CA 91711, USA.

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http://dx.doi.org/10.1387/ijdb.082647mhDOI Listing
August 2009

Gcm protein degradation suppresses proliferation of glial progenitors.

Proc Natl Acad Sci U S A 2009 Apr 3;106(16):6778-83. Epub 2009 Apr 3.

Institute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan.

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http://dx.doi.org/10.1073/pnas.0808899106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672493PMC
April 2009

Event-related functional MRI investigation of vocal pitch variation.

Neuroimage 2009 Jan 10;44(1):175-81. Epub 2008 Sep 10.

Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2008.08.034DOI Listing
January 2009

A Rasch measurement analysis of the use of cohesive devices in writing English as a foreign language by secondary students in Hong Kong.

J Appl Meas 2008 ;9(4):331-43

The University of Western Australia, Western Australia.

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January 2009

Prevalence of structural central nervous system abnormalities in early-onset type 1 diabetes mellitus.

J Pediatr 2008 Sep 28;153(3):385-90. Epub 2008 Apr 28.

Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, Perth, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S002234760800195
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http://dx.doi.org/10.1016/j.jpeds.2008.03.005DOI Listing
September 2008

Participant-collected, mail-delivered oral fluid specimens can replace traditional serosurveys: a demonstration-of-feasibility survey of hepatitis A virus-specific antibodies in adults.

Can J Public Health 2007 Jan-Feb;98(1):37-40

University of British Columbia, Department of Pediatrics, Vaccine Evaluation Centre, Vancouver.

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March 2007

F-box proteins: the key to protein degradation.

J Biomed Sci 2006 Mar;13(2):181-91

Institute of Molecular Biology, Academia Sinica, 115, Taipei, Taiwan.

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http://dx.doi.org/10.1007/s11373-005-9058-2DOI Listing
March 2006

The prevalence of hepatitis A in children in British Columbia.

Can J Infect Dis Med Microbiol 2005 May;16(3):175-9

Vaccine Evaluation Centre, BC Children's Hospital and the University of British Columbia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095024PMC
http://dx.doi.org/10.1155/2005/460983DOI Listing
May 2005

Evidence in support of a docking model for the release of the transcription factor sigma F from the antisigma factor SpoIIAB in Bacillus subtilis.

J Biol Chem 2003 Jun 3;278(23):20898-905. Epub 2003 Apr 3.

Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

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http://dx.doi.org/10.1074/jbc.M302305200DOI Listing
June 2003