Margaret A Shupnik

Margaret A Shupnik

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Margaret A Shupnik

Margaret A Shupnik

Publications by authors named "Margaret A Shupnik"

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29Publications

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A new role for wilms tumor protein 1: differential activities of + KTS and -KTS variants to regulate LHβ transcription.

PLoS One 2015 24;10(1):e0116825. Epub 2015 Jan 24.

Department of Medicine, Division of Endocrinology, University of Virginia School of Medicine, Charlottesville, Virginia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116825PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305298PMC
January 2016

Women at extreme risk for obesity-related carcinogenesis: Baseline endometrial pathology and impact of bariatric surgery on weight, metabolic profiles and quality of life.

Gynecol Oncol 2015 Aug 23;138(2):238-45. Epub 2015 May 23.

Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, VA, United States; School of BABS, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1016/j.ygyno.2015.05.015DOI Listing
August 2015

Estrogen modulation of endosome-associated toll-like receptor 8: an IFNα-independent mechanism of sex-bias in systemic lupus erythematosus.

Clin Immunol 2014 Mar 24;151(1):66-77. Epub 2014 Jan 24.

Division of Rheumatology and Immunology, The Ohio State University, Columbus, OH 43210, USA; Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA; Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2014.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066385PMC
March 2014

AMP-activated protein kinase is a key intermediary in GnRH-stimulated LHβ gene transcription.

Mol Endocrinol 2013 May 21;27(5):828-39. Epub 2013 Mar 21.

Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Virginia, Charlottesville, VA 22903, USA.

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http://dx.doi.org/10.1210/me.2012-1323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634116PMC
May 2013

Introduction to the year in basic science series...2009.

Mol Endocrinol 2010 Jan 17;24(1):250-1. Epub 2009 Dec 17.

Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Medical School, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1210/me.2009-0467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428140PMC
January 2010

Novel actions of estrogen to promote proliferation: integration of cytoplasmic and nuclear pathways.

Steroids 2009 Jul 5;74(7):622-7. Epub 2008 Nov 5.

Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, VA 22903, United States.

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http://dx.doi.org/10.1016/j.steroids.2008.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702758PMC
July 2009

Proteasome regulation of dynamic transcription factor occupancy on the GnRH-stimulated luteinizing hormone beta-subunit promoter.

Mol Endocrinol 2009 Feb 18;23(2):237-50. Epub 2008 Dec 18.

University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1210/me.2008-0098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646621PMC
February 2009

Introduction to The Year in Basic Science series.

Mol Endocrinol 2008 Dec 9;22(12):2741-2. Epub 2008 Oct 9.

Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia, Charlottesville, Virginia 22903, USA.

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http://dx.doi.org/10.1210/me.2008-0378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419405PMC
December 2008

ERbeta in breast cancer--onlooker, passive player, or active protector?

Steroids 2008 Oct 20;73(11):1039-51. Epub 2008 Apr 20.

Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, VA 22903, United States.

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http://dx.doi.org/10.1016/j.steroids.2008.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583259PMC
October 2008

Estrogen enhances gonadotropin-releasing hormone-stimulated transcription of the luteinizing hormone subunit promoters via altered expression of stimulatory and suppressive transcription factors.

Endocrinology 2007 Dec 6;148(12):6083-91. Epub 2007 Sep 6.

Division of Endocrinology, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1210/en.2007-0407DOI Listing
December 2007

Integration of steroid and growth factor pathways in breast cancer: focus on signal transducers and activators of transcription and their potential role in resistance.

Mol Endocrinol 2007 Jul 24;21(7):1499-512. Epub 2007 Apr 24.

Department of Medicine and Cancer Center, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1210/me.2007-0109DOI Listing
July 2007

Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1.

Biol Reprod 2006 Jun 15;74(6):993-8. Epub 2006 Feb 15.

Department of Physiology, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1095/biolreprod.105.049049DOI Listing
June 2006

Stimulation of the novel estrogen receptor-alpha intronic TERP-1 promoter by estrogens, androgen, pituitary adenylate cyclase-activating peptide, and forskolin, and autoregulation by TERP-1 protein.

Endocrinology 2006 Jan 6;147(1):543-51. Epub 2005 Oct 6.

Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Virginia, Charlottesville, Virginia 22903, USA.

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http://dx.doi.org/10.1210/en.2005-1053DOI Listing
January 2006

The estrogen receptor (ER)alpha variant Delta5 exhibits dominant positive activity on ER-regulated promoters in endometrial carcinoma cells.

Endocrinology 2005 Feb 4;146(2):751-9. Epub 2004 Nov 4.

Department of Internal Medicine/Endocrinology, P.O. Box 800578, Health Sciences Center, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1210/en.2004-0825DOI Listing
February 2005

Thyrotropin-releasing hormone-stimulated thyrotropin expression involves islet-brain-1/c-Jun N-terminal kinase interacting protein-1.

Endocrinology 2004 Dec 2;145(12):5623-8. Epub 2004 Sep 2.

First Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan.

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http://dx.doi.org/10.1210/en.2004-0635DOI Listing
December 2004

Role of calcium-calmodulin-dependent protein kinase cascade in thyrotropin (TSH)-releasing hormone induction of TSH and prolactin gene expression.

Endocrinology 2004 Nov 12;145(11):4846-52. Epub 2004 Aug 12.

First Department of Internal Medicine, Faculty of Medicine, Kagawa University, 1750-1 Miki-cho, Kita-gun, Kagawa 761-0793, Japan.

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http://dx.doi.org/10.1210/en.2004-0544DOI Listing
November 2004

Crosstalk between steroid receptors and the c-Src-receptor tyrosine kinase pathways: implications for cell proliferation.

Oncogene 2004 Oct;23(48):7979-89

Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Virginia, Charlottesville, VA 22903, USA.

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http://dx.doi.org/10.1038/sj.onc.1208076DOI Listing
October 2004

Protein kinase A activation of estrogen receptor alpha transcription does not require proteasome activity and protects the receptor from ligand-mediated degradation.

Endocrinology 2004 Jun 19;145(6):2730-8. Epub 2004 Mar 19.

Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Virginia, Box 800578, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1210/en.2003-1470DOI Listing
June 2004

Truncated estrogen receptor product-1 stimulates estrogen receptor alpha transcriptional activity by titration of repressor proteins.

J Biol Chem 2003 Oct 23;278(40):38125-31. Epub 2003 Jul 23.

Department of Pharmacology, Division of Endocrinology and Metabolism, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1074/jbc.M303882200DOI Listing
October 2003

The calcium component of gonadotropin-releasing hormone-stimulated luteinizing hormone subunit gene transcription is mediated by calcium/calmodulin-dependent protein kinase type II.

Endocrinology 2003 Jun;144(6):2409-16

Division of Endocrinology, Department of Medicine, University of Virginia Health Science Center, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1210/en.2002-0013DOI Listing
June 2003

Estrogen receptor-alpha (ERalpha), but not ERbeta, modulates estrogen stimulation of the ERalpha-truncated variant, TERP-1.

Endocrinology 2002 Nov;143(11):4196-202

Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1210/en.2002-220353DOI Listing
November 2002

Disruption of estrogen receptor beta gene impairs spatial learning in female mice.

Proc Natl Acad Sci U S A 2002 Mar 12;99(6):3996-4001. Epub 2002 Mar 12.

Department of Biology and Internal Medicine, University of Virginia, Charlottesville, VA 22903, USA.

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http://dx.doi.org/10.1073/pnas.012032699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC122637PMC
March 2002