Margaret A Richter

Margaret A Richter

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Margaret A Richter

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Pharmacogenetic evaluation of a DISP1 gene variant in antidepressant treatment of obsessive-compulsive disorder.

Hum Psychopharmacol 2018 07 28;33(4):e2659. Epub 2018 Jun 28.

Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/hup.2659DOI Listing
July 2018

Analysis of shared heritability in common disorders of the brain.

Authors:
Verneri Anttila Brendan Bulik-Sullivan Hilary K Finucane Raymond K Walters Jose Bras Laramie Duncan Valentina Escott-Price Guido J Falcone Padhraig Gormley Rainer Malik Nikolaos A Patsopoulos Stephan Ripke Zhi Wei Dongmei Yu Phil H Lee Patrick Turley Benjamin Grenier-Boley Vincent Chouraki Yoichiro Kamatani Claudine Berr Luc Letenneur Didier Hannequin Philippe Amouyel Anne Boland Jean-François Deleuze Emmanuelle Duron Badri N Vardarajan Christiane Reitz Alison M Goate Matthew J Huentelman M Ilyas Kamboh Eric B Larson Ekaterina Rogaeva Peter St George-Hyslop Hakon Hakonarson Walter A Kukull Lindsay A Farrer Lisa L Barnes Thomas G Beach F Yesim Demirci Elizabeth Head Christine M Hulette Gregory A Jicha John S K Kauwe Jeffrey A Kaye James B Leverenz Allan I Levey Andrew P Lieberman Vernon S Pankratz Wayne W Poon Joseph F Quinn Andrew J Saykin Lon S Schneider Amanda G Smith Joshua A Sonnen Robert A Stern Vivianna M Van Deerlin Linda J Van Eldik Denise Harold Giancarlo Russo David C Rubinsztein Anthony Bayer Magda Tsolaki Petra Proitsi Nick C Fox Harald Hampel Michael J Owen Simon Mead Peter Passmore Kevin Morgan Markus M Nöthen Martin Rossor Michelle K Lupton Per Hoffmann Johannes Kornhuber Brian Lawlor Andrew McQuillin Ammar Al-Chalabi Joshua C Bis Agustin Ruiz Mercè Boada Sudha Seshadri Alexa Beiser Kenneth Rice Sven J van der Lee Philip L De Jager Daniel H Geschwind Matthias Riemenschneider Steffi Riedel-Heller Jerome I Rotter Gerhard Ransmayr Bradley T Hyman Carlos Cruchaga Montserrat Alegret Bendik Winsvold Priit Palta Kai-How Farh Ester Cuenca-Leon Nicholas Furlotte Tobias Kurth Lannie Ligthart Gisela M Terwindt Tobias Freilinger Caroline Ran Scott D Gordon Guntram Borck Hieab H H Adams Terho Lehtimäki Juho Wedenoja Julie E Buring Markus Schürks Maria Hrafnsdottir Jouke-Jan Hottenga Brenda Penninx Ville Artto Mari Kaunisto Salli Vepsäläinen Nicholas G Martin Grant W Montgomery Mitja I Kurki Eija Hämäläinen Hailiang Huang Jie Huang Cynthia Sandor Caleb Webber Bertram Muller-Myhsok Stefan Schreiber Veikko Salomaa Elizabeth Loehrer Hartmut Göbel Alfons Macaya Patricia Pozo-Rosich Thomas Hansen Thomas Werge Jaakko Kaprio Andres Metspalu Christian Kubisch Michel D Ferrari Andrea C Belin Arn M J M van den Maagdenberg John-Anker Zwart Dorret Boomsma Nicholas Eriksson Jes Olesen Daniel I Chasman Dale R Nyholt Andreja Avbersek Larry Baum Samuel Berkovic Jonathan Bradfield Russell J Buono Claudia B Catarino Patrick Cossette Peter De Jonghe Chantal Depondt Dennis Dlugos Thomas N Ferraro Jacqueline French Helle Hjalgrim Jennifer Jamnadas-Khoda Reetta Kälviäinen Wolfram S Kunz Holger Lerche Costin Leu Dick Lindhout Warren Lo Daniel Lowenstein Mark McCormack Rikke S Møller Anne Molloy Ping-Wing Ng Karen Oliver Michael Privitera Rodney Radtke Ann-Kathrin Ruppert Thomas Sander Steven Schachter Christoph Schankin Ingrid Scheffer Susanne Schoch Sanjay M Sisodiya Philip Smith Michael Sperling Pasquale Striano Rainer Surges G Neil Thomas Frank Visscher Christopher D Whelan Federico Zara Erin L Heinzen Anthony Marson Felicitas Becker Hans Stroink Fritz Zimprich Thomas Gasser Raphael Gibbs Peter Heutink Maria Martinez Huw R Morris Manu Sharma Mina Ryten Kin Y Mok Sara Pulit Steve Bevan Elizabeth Holliday John Attia Thomas Battey Giorgio Boncoraglio Vincent Thijs Wei-Min Chen Braxton Mitchell Peter Rothwell Pankaj Sharma Cathie Sudlow Astrid Vicente Hugh Markus Christina Kourkoulis Joana Pera Miriam Raffeld Scott Silliman Vesna Boraska Perica Laura M Thornton Laura M Huckins N William Rayner Cathryn M Lewis Monica Gratacos Filip Rybakowski Anna Keski-Rahkonen Anu Raevuori James I Hudson Ted Reichborn-Kjennerud Palmiero Monteleone Andreas Karwautz Katrin Mannik Jessica H Baker Julie K O'Toole Sara E Trace Oliver S P Davis Sietske G Helder Stefan Ehrlich Beate Herpertz-Dahlmann Unna N Danner Annemarie A van Elburg Maurizio Clementi Monica Forzan Elisa Docampo Jolanta Lissowska Joanna Hauser Alfonso Tortorella Mario Maj Fragiskos Gonidakis Konstantinos Tziouvas Hana Papezova Zeynep Yilmaz Gudrun Wagner Sarah Cohen-Woods Stefan Herms Antonio Julià Raquel Rabionet Danielle M Dick Samuli Ripatti Ole A Andreassen Thomas Espeseth Astri J Lundervold Vidar M Steen Dalila Pinto Stephen W Scherer Harald Aschauer Alexandra Schosser Lars Alfredsson Leonid Padyukov Katherine A Halmi James Mitchell Michael Strober Andrew W Bergen Walter Kaye Jin Peng Szatkiewicz Bru Cormand Josep Antoni Ramos-Quiroga Cristina Sánchez-Mora Marta Ribasés Miguel Casas Amaia Hervas Maria Jesús Arranz Jan Haavik Tetyana Zayats Stefan Johansson Nigel Williams Astrid Dempfle Aribert Rothenberger Jonna Kuntsi Robert D Oades Tobias Banaschewski Barbara Franke Jan K Buitelaar Alejandro Arias Vasquez Alysa E Doyle Andreas Reif Klaus-Peter Lesch Christine Freitag Olga Rivero Haukur Palmason Marcel Romanos Kate Langley Marcella Rietschel Stephanie H Witt Soeren Dalsgaard Anders D Børglum Irwin Waldman Beth Wilmot Nikolas Molly Claiton H D Bau Jennifer Crosbie Russell Schachar Sandra K Loo James J McGough Eugenio H Grevet Sarah E Medland Elise Robinson Lauren A Weiss Elena Bacchelli Anthony Bailey Vanessa Bal Agatino Battaglia Catalina Betancur Patrick Bolton Rita Cantor Patrícia Celestino-Soper Geraldine Dawson Silvia De Rubeis Frederico Duque Andrew Green Sabine M Klauck Marion Leboyer Pat Levitt Elena Maestrini Shrikant Mane Daniel Moreno- De-Luca Jeremy Parr Regina Regan Abraham Reichenberg Sven Sandin Jacob Vorstman Thomas Wassink Ellen Wijsman Edwin Cook Susan Santangelo Richard Delorme Bernadette Rogé Tiago Magalhaes Dan Arking Thomas G Schulze Robert C Thompson Jana Strohmaier Keith Matthews Ingrid Melle Derek Morris Douglas Blackwood Andrew McIntosh Sarah E Bergen Martin Schalling Stéphane Jamain Anna Maaser Sascha B Fischer Céline S Reinbold Janice M Fullerton José Guzman-Parra Fermin Mayoral Peter R Schofield Sven Cichon Thomas W Mühleisen Franziska Degenhardt Johannes Schumacher Michael Bauer Philip B Mitchell Elliot S Gershon John Rice James B Potash Peter P Zandi Nick Craddock I Nicol Ferrier Martin Alda Guy A Rouleau Gustavo Turecki Roel Ophoff Carlos Pato Adebayo Anjorin Eli Stahl Markus Leber Piotr M Czerski Cristiana Cruceanu Ian R Jones Danielle Posthuma Till F M Andlauer Andreas J Forstner Fabian Streit Bernhard T Baune Tracy Air Grant Sinnamon Naomi R Wray Donald J MacIntyre David Porteous Georg Homuth Margarita Rivera Jakob Grove Christel M Middeldorp Ian Hickie Michele Pergadia Divya Mehta Johannes H Smit Rick Jansen Eco de Geus Erin Dunn Qingqin S Li Matthias Nauck Robert A Schoevers Aartjan Tf Beekman James A Knowles Alexander Viktorin Paul Arnold Cathy L Barr Gabriel Bedoya-Berrio O Joseph Bienvenu Helena Brentani Christie Burton Beatriz Camarena Carolina Cappi Danielle Cath Maria Cavallini Daniele Cusi Sabrina Darrow Damiaan Denys Eske M Derks Andrea Dietrich Thomas Fernandez Martijn Figee Nelson Freimer Gloria Gerber Marco Grados Erica Greenberg Gregory L Hanna Andreas Hartmann Matthew E Hirschtritt Pieter J Hoekstra Alden Huang Chaim Huyser Cornelia Illmann Michael Jenike Samuel Kuperman Bennett Leventhal Christine Lochner Gholson J Lyon Fabio Macciardi Marcos Madruga-Garrido Irene A Malaty Athanasios Maras Lauren McGrath Eurípedes C Miguel Pablo Mir Gerald Nestadt Humberto Nicolini Michael S Okun Andrew Pakstis Peristera Paschou John Piacentini Christopher Pittenger Kerstin Plessen Vasily Ramensky Eliana M Ramos Victor Reus Margaret A Richter Mark A Riddle Mary M Robertson Veit Roessner Maria Rosário Jack F Samuels Paul Sandor Dan J Stein Fotis Tsetsos Filip Van Nieuwerburgh Sarah Weatherall Jens R Wendland Tomasz Wolanczyk Yulia Worbe Gwyneth Zai Fernando S Goes Nicole McLaughlin Paul S Nestadt Hans-Jorgen Grabe Christel Depienne Anuar Konkashbaev Nuria Lanzagorta Ana Valencia-Duarte Elvira Bramon Nancy Buccola Wiepke Cahn Murray Cairns Siow A Chong David Cohen Benedicto Crespo-Facorro James Crowley Michael Davidson Lynn DeLisi Timothy Dinan Gary Donohoe Elodie Drapeau Jubao Duan Lieuwe Haan David Hougaard Sena Karachanak-Yankova Andrey Khrunin Janis Klovins Vaidutis Kučinskas Jimmy Lee Chee Keong Svetlana Limborska Carmel Loughland Jouko Lönnqvist Brion Maher Manuel Mattheisen Colm McDonald Kieran C Murphy Igor Nenadic Jim van Os Christos Pantelis Michele Pato Tracey Petryshen Digby Quested Panos Roussos Alan R Sanders Ulrich Schall Sibylle G Schwab Kang Sim Hon-Cheong So Elisabeth Stögmann Mythily Subramaniam Draga Toncheva John Waddington James Walters Mark Weiser Wei Cheng Robert Cloninger David Curtis Pablo V Gejman Frans Henskens Morten Mattingsdal Sang-Yun Oh Rodney Scott Bradley Webb Gerome Breen Claire Churchhouse Cynthia M Bulik Mark Daly Martin Dichgans Stephen V Faraone Rita Guerreiro Peter Holmans Kenneth S Kendler Bobby Koeleman Carol A Mathews Alkes Price Jeremiah Scharf Pamela Sklar Julie Williams Nicholas W Wood Chris Cotsapas Aarno Palotie Jordan W Smoller Patrick Sullivan Jonathan Rosand Aiden Corvin Benjamin M Neale Jonathan M Schott Richard Anney Josephine Elia Maria Grigoroiu-Serbanescu Howard J Edenberg Robin Murray

Science 2018 06;360(6395)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1126/science.aap8757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097237PMC
June 2018

Investigating Cortical Inhibition in First-Degree Relatives and Probands in Schizophrenia.

Sci Rep 2017 02 27;7:43629. Epub 2017 Feb 27.

Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/srep43629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378912PMC
February 2017

A Pilot Test of the Additive Benefits of Physical Exercise to CBT for OCD.

Cogn Behav Ther 2015 4;44(4):328-40. Epub 2015 Mar 4.

a Sunnybrook Health Sciences Centre , 2075 Bayview Ave., Toronto , Ontario , Canada M4N 3M5.

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http://dx.doi.org/10.1080/16506073.2015.1016448DOI Listing
March 2016

Obsessive-compulsive disorder (OCD): Practical strategies for pharmacological and somatic treatment in adults.

Psychiatry Res 2015 May 11;227(1):114-25. Epub 2015 Feb 11.

Obsessive Compulsive Disorder Clinic, Department of Psychology, McGill University Health Centre, and Department of Psychiatry, McGill University, Montreal, PQ, Canada.

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http://dx.doi.org/10.1016/j.psychres.2014.12.003DOI Listing
May 2015

Meta-analysis and association of brain-derived neurotrophic factor (BDNF) gene with obsessive-compulsive disorder.

Psychiatr Genet 2015 Apr;25(2):95-6

aNeurogenetics Section, Centre for Addiction and Mental Health bDepartment of Psychiatry and Institute of Medical Science, University of Toronto cDepartment of Psychiatry and Program in Genetics and Genome Biology, Hospital for Sick Children dFrederick W. Thompson Anxiety Disorders Centre and Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/YPG.0000000000000077DOI Listing
April 2015

Evidence for inhibitory deficits in the prefrontal cortex in schizophrenia.

Brain 2015 Feb 17;138(Pt 2):483-97. Epub 2014 Dec 17.

1 Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada

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http://dx.doi.org/10.1093/brain/awu360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306823PMC
February 2015

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

Authors:
Dongmei Yu Carol A Mathews Jeremiah M Scharf Benjamin M Neale Lea K Davis Eric R Gamazon Eske M Derks Patrick Evans Christopher K Edlund Jacquelyn Crane Jesen A Fagerness Lisa Osiecki Patience Gallagher Gloria Gerber Stephen Haddad Cornelia Illmann Lauren M McGrath Catherine Mayerfeld Sampath Arepalli Cristina Barlassina Cathy L Barr Laura Bellodi Fortu Benarroch Gabriel Bedoya Berrió O Joseph Bienvenu Donald W Black Michael H Bloch Helena Brentani Ruth D Bruun Cathy L Budman Beatriz Camarena Desmond D Campbell Carolina Cappi Julio C Cardona Silgado Maria C Cavallini Denise A Chavira Sylvain Chouinard Edwin H Cook M R Cookson Vladimir Coric Bernadette Cullen Daniele Cusi Richard Delorme Damiaan Denys Yves Dion Valsama Eapen Karin Egberts Peter Falkai Thomas Fernandez Eduardo Fournier Helena Garrido Daniel Geller Donald L Gilbert Simon L Girard Hans J Grabe Marco A Grados Benjamin D Greenberg Varda Gross-Tsur Edna Grünblatt John Hardy Gary A Heiman Sian M J Hemmings Luis D Herrera Dianne M Hezel Pieter J Hoekstra Joseph Jankovic James L Kennedy Robert A King Anuar I Konkashbaev Barbara Kremeyer Roger Kurlan Nuria Lanzagorta Marion Leboyer James F Leckman Leonhard Lennertz Chunyu Liu Christine Lochner Thomas L Lowe Sara Lupoli Fabio Macciardi Wolfgang Maier Paolo Manunta Maurizio Marconi James T McCracken Sandra C Mesa Restrepo Rainald Moessner Priya Moorjani Jubel Morgan Heike Muller Dennis L Murphy Allan L Naarden Erika Nurmi William Cornejo Ochoa Roel A Ophoff Andrew J Pakstis Michele T Pato Carlos N Pato John Piacentini Christopher Pittenger Yehuda Pollak Scott L Rauch Tobias Renner Victor I Reus Margaret A Richter Mark A Riddle Mary M Robertson Roxana Romero Maria C Rosário David Rosenberg Stephan Ruhrmann Chiara Sabatti Erika Salvi Aline S Sampaio Jack Samuels Paul Sandor Susan K Service Brooke Sheppard Harvey S Singer Jan H Smit Dan J Stein Eric Strengman Jay A Tischfield Maurizio Turiel Ana V Valencia Duarte Homero Vallada Jeremy Veenstra-VanderWeele Susanne Walitza Ying Wang Mike Weale Robert Weiss Jens R Wendland Herman G M Westenberg Yin Yao Shugart Ana G Hounie Euripedes C Miguel Humberto Nicolini Michael Wagner Andres Ruiz-Linares Danielle C Cath William McMahon Danielle Posthuma Ben A Oostra Gerald Nestadt Guy A Rouleau Shaun Purcell Michael A Jenike Peter Heutink Gregory L Hanna David V Conti Paul D Arnold Nelson B Freimer S Evelyn Stewart James A Knowles Nancy J Cox David L Pauls

Am J Psychiatry 2015 Jan 31;172(1):82-93. Epub 2014 Oct 31.

From the Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetics Research, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston; the Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Mass.; the Department of Psychiatry, University of California, San Francisco; the Department of Neurology, Massachusetts General Hospital, Boston; the Division of Cognitive and Behavioral Neurology, Brigham and Women's Hospital, Boston; the Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago; the Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam; the Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine, University of Southern California, Los Angeles; the Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Md.; the Genomic and Bioinformatic Unit, Filarete Foundation, Milan, Italy; the Department of Health Sciences, Graduate School of Nephrology, University of Milan, Milan; the Toronto Western Research Institute, University Health Network, Toronto; Hospital for Sick Children, Toronto; Università Vita-Salute San Raffaele, Milan; the Herman Dana Division of Child and Adolescent Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem; Universidad de Antioquia, Universidad Pontificia Bolivariana, Medellín, Colombia; the Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore; the Department of Psychiatry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; the Child Study Center and the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn.; the Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil; North Shore-Long Island Jewish Medical Center and North Shore-Lo

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http://dx.doi.org/10.1176/appi.ajp.2014.13101306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282594PMC
January 2015

Second generation antipsychotic-induced obsessive-compulsive symptoms in schizophrenia: a review of the experimental literature.

Curr Psychiatry Rep 2014 Nov;16(11):510

Campbell Family Mental Health Research Institute, Center for Addiction and Mental Health, 250 College Street, Toronto, ON, M5T 1R8, Canada.

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http://link.springer.com/10.1007/s11920-014-0510-8
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http://dx.doi.org/10.1007/s11920-014-0510-8DOI Listing
November 2014

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.

Authors:
Lauren M McGrath Dongmei Yu Christian Marshall Lea K Davis Bhooma Thiruvahindrapuram Bingbin Li Carolina Cappi Gloria Gerber Aaron Wolf Frederick A Schroeder Lisa Osiecki Colm O'Dushlaine Andrew Kirby Cornelia Illmann Stephen Haddad Patience Gallagher Jesen A Fagerness Cathy L Barr Laura Bellodi Fortu Benarroch O Joseph Bienvenu Donald W Black Michael H Bloch Ruth D Bruun Cathy L Budman Beatriz Camarena Danielle C Cath Maria C Cavallini Sylvain Chouinard Vladimir Coric Bernadette Cullen Richard Delorme Damiaan Denys Eske M Derks Yves Dion Maria C Rosário Valsama Eapen Patrick Evans Peter Falkai Thomas V Fernandez Helena Garrido Daniel Geller Hans J Grabe Marco A Grados Benjamin D Greenberg Varda Gross-Tsur Edna Grünblatt Gary A Heiman Sian M J Hemmings Luis D Herrera Ana G Hounie Joseph Jankovic James L Kennedy Robert A King Roger Kurlan Nuria Lanzagorta Marion Leboyer James F Leckman Leonhard Lennertz Christine Lochner Thomas L Lowe Gholson J Lyon Fabio Macciardi Wolfgang Maier James T McCracken William McMahon Dennis L Murphy Allan L Naarden Benjamin M Neale Erika Nurmi Andrew J Pakstis Michele T Pato Carlos N Pato John Piacentini Christopher Pittenger Yehuda Pollak Victor I Reus Margaret A Richter Mark Riddle Mary M Robertson David Rosenberg Guy A Rouleau Stephan Ruhrmann Aline S Sampaio Jack Samuels Paul Sandor Brooke Sheppard Harvey S Singer Jan H Smit Dan J Stein Jay A Tischfield Homero Vallada Jeremy Veenstra-VanderWeele Susanne Walitza Ying Wang Jens R Wendland Yin Yao Shugart Euripedes C Miguel Humberto Nicolini Ben A Oostra Rainald Moessner Michael Wagner Andres Ruiz-Linares Peter Heutink Gerald Nestadt Nelson Freimer Tracey Petryshen Danielle Posthuma Michael A Jenike Nancy J Cox Gregory L Hanna Helena Brentani Stephen W Scherer Paul D Arnold S Evelyn Stewart Carol A Mathews James A Knowles Edwin H Cook David L Pauls Kai Wang Jeremiah M Scharf

J Am Acad Child Adolesc Psychiatry 2014 Aug 24;53(8):910-9. Epub 2014 Jun 24.

Massachusetts General Hospital, Boston; Brigham and Womens Hospital, Boston; Harvard-MIT Broad Institute, Boston. Electronic address:

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http://dx.doi.org/10.1016/j.jaac.2014.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218748PMC
August 2014

Is anxiety best conceived as a unitary condition? The benefits of lumping compared with splitting . . .

Can J Psychiatry 2014 Jun;59(6):291-3

Head of Frederick W Thompson Anxiety Disorders Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario; Associate Professor of Psychiatry, University of Toronto, Toronto, Ontario.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079147PMC
http://dx.doi.org/10.1177/070674371405900601DOI Listing
June 2014

Pharmacogenetics of antidepressant treatment in obsessive-compulsive disorder: an update and implications for clinicians.

Pharmacogenomics 2014 Jun;15(8):1147-57

Neurogenetics Section, Centre for Addiction & Mental Health, Toronto, ON M5T 1R8, Canada.

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https://www.futuremedicine.com/doi/10.2217/pgs.14.83
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http://dx.doi.org/10.2217/pgs.14.83DOI Listing
June 2014

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.

Authors:
Lea K Davis Dongmei Yu Clare L Keenan Eric R Gamazon Anuar I Konkashbaev Eske M Derks Benjamin M Neale Jian Yang S Hong Lee Patrick Evans Cathy L Barr Laura Bellodi Fortu Benarroch Gabriel Bedoya Berrio Oscar J Bienvenu Michael H Bloch Rianne M Blom Ruth D Bruun Cathy L Budman Beatriz Camarena Desmond Campbell Carolina Cappi Julio C Cardona Silgado Danielle C Cath Maria C Cavallini Denise A Chavira Sylvain Chouinard David V Conti Edwin H Cook Vladimir Coric Bernadette A Cullen Dieter Deforce Richard Delorme Yves Dion Christopher K Edlund Karin Egberts Peter Falkai Thomas V Fernandez Patience J Gallagher Helena Garrido Daniel Geller Simon L Girard Hans J Grabe Marco A Grados Benjamin D Greenberg Varda Gross-Tsur Stephen Haddad Gary A Heiman Sian M J Hemmings Ana G Hounie Cornelia Illmann Joseph Jankovic Michael A Jenike James L Kennedy Robert A King Barbara Kremeyer Roger Kurlan Nuria Lanzagorta Marion Leboyer James F Leckman Leonhard Lennertz Chunyu Liu Christine Lochner Thomas L Lowe Fabio Macciardi James T McCracken Lauren M McGrath Sandra C Mesa Restrepo Rainald Moessner Jubel Morgan Heike Muller Dennis L Murphy Allan L Naarden William Cornejo Ochoa Roel A Ophoff Lisa Osiecki Andrew J Pakstis Michele T Pato Carlos N Pato John Piacentini Christopher Pittenger Yehuda Pollak Scott L Rauch Tobias J Renner Victor I Reus Margaret A Richter Mark A Riddle Mary M Robertson Roxana Romero Maria C Rosàrio David Rosenberg Guy A Rouleau Stephan Ruhrmann Andres Ruiz-Linares Aline S Sampaio Jack Samuels Paul Sandor Brooke Sheppard Harvey S Singer Jan H Smit Dan J Stein E Strengman Jay A Tischfield Ana V Valencia Duarte Homero Vallada Filip Van Nieuwerburgh Jeremy Veenstra-Vanderweele Susanne Walitza Ying Wang Jens R Wendland Herman G M Westenberg Yin Yao Shugart Euripedes C Miguel William McMahon Michael Wagner Humberto Nicolini Danielle Posthuma Gregory L Hanna Peter Heutink Damiaan Denys Paul D Arnold Ben A Oostra Gerald Nestadt Nelson B Freimer David L Pauls Naomi R Wray S Evelyn Stewart Carol A Mathews James A Knowles Nancy J Cox Jeremiah M Scharf

PLoS Genet 2013 Oct 24;9(10):e1003864. Epub 2013 Oct 24.

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812053PMC
October 2013

The AmpliChip® CYP450 test and response to treatment in schizophrenia and obsessive compulsive disorder: a pilot study and focus on cases with abnormal CYP2D6 drug metabolism.

Genet Test Mol Biomarkers 2012 Aug 9;16(8):897-903. Epub 2012 Jul 9.

Pharmacogenetics Research Clinic, Neurogenetics Section, Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1089/gtmb.2011.0327DOI Listing
August 2012

Evidence for cortical inhibitory and excitatory dysfunction in obsessive compulsive disorder.

Neuropsychopharmacology 2012 Apr 14;37(5):1144-51. Epub 2011 Dec 14.

Director of OCD and Related Disorders, Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/npp.2011.300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306876PMC
April 2012

Disgust recognition in obsessive-compulsive disorder: diagnostic comparisons and posttreatment effects.

Can J Psychiatry 2012 Mar;57(3):177-83

Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario.

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http://dx.doi.org/10.1177/070674371205700307DOI Listing
March 2012

Pharmacogenetics of obsessive-compulsive disorders.

Pharmacogenomics 2012 Jan;13(1):71-81

Neurogenetics Section, Centre for Addiction & Mental Health & University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.2217/pgs.11.133DOI Listing
January 2012

Age at onset in Canadian OCD patients: mixture analysis and systematic comparison with other studies.

J Affect Disord 2011 Sep 4;133(1-2):300-4. Epub 2011 May 4.

Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jad.2011.03.041DOI Listing
September 2011

Psychological treatment of obsessive-compulsive disorder in patients with major depression: a pilot randomized controlled trial.

Can J Psychiatry 2009 Dec;54(12):846-51

Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario.

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http://dx.doi.org/10.1177/070674370905401208DOI Listing
December 2009

The GABA(A)-receptor γ2 (GABRG2) gene in obsessive-compulsive disorder.

Braz J Psychiatry 2009 Dec;31(4):328-31

Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.

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December 2009

Quality of life in treatment-seeking patients with obsessive-compulsive disorder with and without major depressive disorder.

Can J Psychiatry 2009 Jul;54(7):460-7

Department of Psychiatry, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario.

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http://dx.doi.org/10.1177/070674370905400707DOI Listing
July 2009

Obsessive beliefs in first-degree relatives of patients with OCD: a test of the cognitive vulnerability model.

J Anxiety Disord 2009 Jan 7;23(1):145-9. Epub 2008 Jun 7.

Anxiety Disorders Clinic, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.janxdis.2008.06.001DOI Listing
January 2009

Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder.

Arch Gen Psychiatry 2006 Jul;63(7):769-76

Neurogenetics Section, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario M5T 1R8, Canada.

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http://dx.doi.org/10.1001/archpsyc.63.7.769DOI Listing
July 2006

Tumor necrosis factor-alpha gene is not associated with obsessive-compulsive disorder.

Psychiatr Genet 2006 Feb;16(1):43-5

Institute of Medical Science, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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February 2006

Evidence for the gamma-amino-butyric acid type B receptor 1 (GABBR1) gene as a susceptibility factor in obsessive-compulsive disorder.

Am J Med Genet B Neuropsychiatr Genet 2005 Apr;134B(1):25-9

Neurogenetics Section, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1002/ajmg.b.30152DOI Listing
April 2005

The impact of personality on symptom expression in obsessive-compulsive disorder.

J Nerv Ment Dis 2005 Apr;193(4):231-6

Anxiety Disorders Clinic, Mood and Anxiety Program, Centre for Addiction and Mental Health, University of Toronto, Ontario M5T 1R8, Canada.

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http://dx.doi.org/10.1097/01.nmd.0000158378.14019.89DOI Listing
April 2005

The relationship between miscellaneous symptoms and major symptom factors in obsessive-compulsive disorder.

Behav Res Ther 2004 Dec;42(12):1453-67

Department of Psychology, Trent University, Peterborough, Ont K9J 7B8, Canada.

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http://dx.doi.org/10.1016/j.brat.2003.09.006DOI Listing
December 2004

Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: a preliminary study.

Psychopharmacology (Berl) 2004 Aug 9;174(4):530-8. Epub 2004 Apr 9.

Child Psychiatry Program, Neurogenetics Section, 1st Floor, Centre for Addiction and Mental Health, University of Toronto, 250 College Street, Toronto, Ontario, Canada M5T 1R8.

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http://dx.doi.org/10.1007/s00213-004-1847-1DOI Listing
August 2004

Genetics of anxiety disorders.

Curr Psychiatry Rep 2004 Aug;6(4):243-54

Anxiety Disorders Clinic, Centre for Addiction and Mental Health, University of Toronto, 250 College Street, Toronto, ON M5T 1R8, Canada.

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August 2004

Myelin oligodendrocyte glycoprotein (MOG) gene is associated with obsessive-compulsive disorder.

Am J Med Genet B Neuropsychiatr Genet 2004 Aug;129B(1):64-8

Neurogenetics Section, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/ajmg.b.30077DOI Listing
August 2004

Obsessive-compulsive spectrum conditions in obsessive-compulsive disorder and other anxiety disorders.

Depress Anxiety 2003 ;18(3):118-27

Anxiety Disorders Clinic, Centre for Addiction and Mental Health, Clarke Division, and Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/da.10126DOI Listing
March 2004

Quality of life in OCD: differential impact of obsessions, compulsions, and depression comorbidity.

Can J Psychiatry 2003 Mar;48(2):72-7

Department of Psychiatry, University of Toronto, Toronto, Ontario.

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http://dx.doi.org/10.1177/070674370304800202DOI Listing
March 2003

Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS).

Pediatr Infect Dis J 2002 Jan;21(1):67-71

Center for Addiction and Mental Health, Clarke Institute Division, and Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1097/00006454-200201000-00017DOI Listing
January 2002