Marek Minarik

Department of Internal Medicine, 1st Faculty of Medicine, Charles University and Military University Hospital, 169 02 Prague, Czech Republic; Center for Applied Genomics of Solid Tumors, Genomac Research Institute, 161 00 Prague, Czech Republic.

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October 2016

The first European family with gastric adenocarcinoma and proximal polyposis of the stomach: case report and review of the literature.

Authors:

Rudolf Repak Darina Kohoutova Miroslav Podhola Stanislav Rejchrt Marek Minarik Lucie Benesova Michal Lesko Jan Bures

Gastrointest Endosc 2016 Oct 23;84(4):718-25. Epub 2016 Jun 23.

2nd Department of Internal Medicine - Gastroenterology, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Hradec Kralove, Czech Republic.

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October 2016

Longitudinal molecular characterization of endoscopic specimens from colorectal lesions.

Authors:

Petra Minarikova Lucie Benesova Tereza Halkova Barbora Belsanova Stepan Suchanek Jiri Cyrany Inna Tuckova Jan Bures Miroslav Zavoral Marek Minarik

World J Gastroenterol 2016 May;22(20):4936-45

Petra Minarikova, Stepan Suchanek, Miroslav Zavoral, Inna Tuckova, Marek Minarik, Department of Internal Medicine, 1st Faculty of Medicine of Charles University and Military University Hospital, CZ 16902 Prague, Czech Republic.

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May 2016

Change in Serum Lactate Dehydrogenase Is Associated with Outcome of Patients with Advanced-stage NSCLC Treated with Erlotinib.

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Ondrej Topolcan Jaroslav Racek Martin Svaton Radek Kucera Marek Minarik Lucie Benesova Zbynek Bortlicek Renata Chloupkova Alexandr Poprach Tomas Buchler

Anticancer Res 2016 May;36(5):2459-65

Department of Oncology and First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic.

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May 2016

The Prognostic Role of KRAS Mutation in Patients with Advanced NSCLC Treated with Second- or Third-line Chemotherapy.

Authors:

Martin Svaton Ondrej Fiala Milos Pesek Zbynek Bortlicek Marek Minarik Lucie Benesova Ondrej Topolcan

Anticancer Res 2016 Mar;36(3):1077-82

Department of Nuclear Medicine, Faculty of Medicine in Pilsen, Charles University in Prague, Prague, Czech Republic.

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March 2016

[KRAS mutation assay on EUS-FNA specimens from pacients with pancreatic mass].

Authors:

Bohuš Bunganič Tereza Hálková Lucie Benešová Barbora Belšánová Martin Laclav Martina Hrůzová Eva Traboulsi Přemysl Frič Štěpán Suchánek Marek Minárik Miroslav Zavoral

Cas Lek Cesk 2016;155(1):48-51

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June 2017

Epidermal Growth Factor Receptor Gene Amplification in Patients with Advanced-stage NSCLC.

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Marek Minarik Lucie Benesova Ondrej Sorejs Martin Svaton Zbynek Bortlicek Radek Kucera Ondrej Topolcan

Anticancer Res 2016 Jan;36(1):455-60

Department of Nuclear Medicine, Medical School and Teaching Hospital Pilsen, Charles University in Prague, Prague, Czech Republic.

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January 2016

Pemetrexed Versus Erlotinib in the Second-line Treatment of Patients with Advanced-stage Non-squamous NSCLC Harboring Wild-type EGFR Gene.

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Martin Svaton Marek Minarik Lucie Benesova Zbynek Bortlicek Radek Kucera Ondrej Topolcan

Anticancer Res 2016 Jan;36(1):447-53

Department of Nuclear Medicine, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, Prague, Czech Republic.

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January 2016

High serum level of C-reactive protein is associated with worse outcome of patients with advanced-stage NSCLC treated with erlotinib.

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Ondrej Topolcan Jaroslav Racek Marek Minarik Lucie Benesova Zbynek Bortlicek Alexandr Poprach Tomas Buchler

Tumour Biol 2015 Dec 19;36(12):9215-22. Epub 2015 Jun 19.

Department of Oncology and First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic.

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December 2015

MicroRNAs in Pancreatic Cancer: Involvement in Carcinogenesis and Potential Use for Diagnosis and Prognosis.

Authors:

Tereza Halkova Romana Cuperkova Marek Minarik Lucie Benesova

Gastroenterol Res Pract 2015 19;2015:892903. Epub 2015 Apr 19.

Center for Applied Genomics of Solid Tumors (CEGES), Genomac Research Institute, Drnovska 1112/60, 161 00 Prague 6, Czech Republic.

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May 2015

Statins augment efficacy of EGFR-TKIs in patients with advanced-stage non-small cell lung cancer harbouring KRAS mutation.

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Marek Minarik Lucie Benesova Zbynek Bortlicek Ondrej Topolcan

Tumour Biol 2015 Aug 22;36(8):5801-5. Epub 2015 Feb 22.

Department of Oncology and Radiotherapy, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, alej Svobody 80, 304 60, Pilsen, Czech Republic,

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August 2015

Variants in miRNA regulating cardiac growth are not a common cause of hypertrophic cardiomyopathy.

Authors:

Karol Curila Lucie Benesova Pavol Tomasov Barbora Belsanova Petr Widimsky Marek Minarik David Zemanek Josef Veselka Pavel Gregor

Cardiology 2015 24;130(3):137-42. Epub 2015 Jan 24.

Cardiocenter, Department of Cardiology, 3rd Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic.

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November 2015

Predictive and prognostic significance of sodium levels in patients with NSCLC treated by erlotinib.

Authors:

Martin Svaton Ondrej Fiala Milos Pesek Frantisek Bruha Petr Mukensnabl Jaroslav Racek Marek Minarik Zdenek Bortlicek

Anticancer Res 2014 Dec;34(12):7461-5

Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic.

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December 2014

The role of neuron-specific enolase (NSE) and thymidine kinase (TK) levels in prediction of efficacy ofEGFR-TKIs in patients with advanced-stage NSCLC [corrected].

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Lucie Benesova Marek Minarik Zbynek Bortlicek Ondrej Topolcan

Anticancer Res 2014 Sep;34(9):5193-8

Department of Nuclear Medicine, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, Pilsen, Czech Republic.

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September 2014

Retreatment with erlotinib of a patient with metastatic NSCLC harboring EGFR mutation: a case report.

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Gabriela Krakorova Lucie Benesova Marek Minarik

Tumori 2014 May-Jun;100(3):e70-3

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November 2014

Predictive role of CEA and CYFRA 21-1 in patients with advanced-stage NSCLC treated with erlotinib.

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Lucie Benesova Marek Minarik Zbynek Bortlicek Ondrej Topolcan

Anticancer Res 2014 Jun;34(6):3205-10

Department of Nuclear Medicine, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, Czech Republic.

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June 2014

Toward male individualization with rapidly mutating y-chromosomal short tandem repeats.

Authors:

Kaye N Ballantyne Arwin Ralf Rachid Aboukhalid Niaz M Achakzai Maria J Anjos Qasim Ayub Jože Balažic Jack Ballantyne David J Ballard Burkhard Berger Cecilia Bobillo Mehdi Bouabdellah Helen Burri Tomas Capal Stefano Caratti Jorge Cárdenas François Cartault Elizeu F Carvalho Monica Carvalho Baowen Cheng Michael D Coble David Comas Daniel Corach Maria E D'Amato Sean Davison Peter de Knijff Maria Corazon A De Ungria Ronny Decorte Tadeusz Dobosz Berit M Dupuy Samir Elmrghni Mateusz Gliwiński Sara C Gomes Laurens Grol Cordula Haas Erin Hanson Jürgen Henke Lotte Henke Fabiola Herrera-Rodríguez Carolyn R Hill Gunilla Holmlund Katsuya Honda Uta-Dorothee Immel Shota Inokuchi Mark A Jobling Mahmoud Kaddura Jong S Kim Soon H Kim Wook Kim Turi E King Eva Klausriegler Daniel Kling Lejla Kovačević Leda Kovatsi Paweł Krajewski Sergey Kravchenko Maarten H D Larmuseau Eun Young Lee Ruediger Lessig Ludmila A Livshits Damir Marjanović Marek Minarik Natsuko Mizuno Helena Moreira Niels Morling Meeta Mukherjee Patrick Munier Javaregowda Nagaraju Franz Neuhuber Shengjie Nie Premlaphat Nilasitsataporn Takeki Nishi Hye H Oh Jill Olofsson Valerio Onofri Jukka U Palo Horolma Pamjav Walther Parson Michal Petlach Christopher Phillips Rafal Ploski Samayamantri P R Prasad Dragan Primorac Gludhug A Purnomo Josephine Purps Hector Rangel-Villalobos Krzysztof Rębała Budsaba Rerkamnuaychoke Danel Rey Gonzalez Carlo Robino Lutz Roewer Alexandra Rosa Antti Sajantila Andrea Sala Jazelyn M Salvador Paula Sanz Cornelia Schmitt Anil K Sharma Dayse A Silva Kyoung-Jin Shin Titia Sijen Miriam Sirker Daniela Siváková Vedrana Skaro Carlos Solano-Matamoros Luis Souto Vlastimil Stenzl Herawati Sudoyo Denise Syndercombe-Court Adriano Tagliabracci Duncan Taylor Andreas Tillmar Iosif S Tsybovsky Chris Tyler-Smith Kristiaan J van der Gaag Daniel Vanek Antónia Völgyi Denise Ward Patricia Willemse Eric P H Yap Rita Y Y Yong Irena Zupanič Pajnič Manfred Kayser

Hum Mutat 2014 Aug 14;35(8):1021-32. Epub 2014 Jul 14.

Department of Forensic Molecular Biology, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands; Office of the Chief Forensic Scientist, Victoria Police Forensic Services Department, Macleod, Victoria, Australia.

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August 2014

Colorectal cancer screening: 20 years of development and recent progress.

Authors:

Miroslav Zavoral Stepan Suchanek Ondrej Majek Premysl Fric Petra Minarikova Marek Minarik Bohumil Seifert Ladislav Dusek

World J Gastroenterol 2014 Apr;20(14):3825-34

Miroslav Zavoral, Stepan Suchanek, Premysl Fric, Petra Minarikova, Department of Medicine, 1 Faculty of Medicine, Military University Hospital, Charles University, CZ 169 02 Prague, Czech Republic.

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April 2014

Colorectal cancer prevention in the Czech Republic: time trends in performance indicators and current situation after 10 years of screening.

Authors:

Stepan Suchanek Ondrej Majek Gabriela Vojtechova Petra Minarikova Barbora Rotnaglova Bohumil Seifert Marek Minarik Pavel Kozeny Ladislav Dusek Miroslav Zavoral

Eur J Cancer Prev 2014 Jan;23(1):18-26

aDepartment of Medicine, 1st Faculty of Medicine, Military University Hospital b1st Faculty of Medicine, Institute of General Practice, Charles University cCenter for Applied Genomics of Solid Tumors, Genomac Research Institute dNational Reference Centre, Prague eInstitute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic.

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January 2014

Sequential treatment of advanced-stage lung adenocarcinoma harboring wild-type EGFR gene: second-line pemetrexed followed by third-line erlotinib versus the reverse sequence.

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Lucie Benesova Zbynek Bortlicek Marek Minarik

Anticancer Res 2013 Aug;33(8):3397-402

Department of Oncology and Radiotherapy, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, alej Svobody 80, CZ-304 60 Pilsen, Czech Republic.

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August 2013

Gene mutations in squamous cell NSCLC: insignificance of EGFR, KRAS and PIK3CA mutations in prediction of EGFR-TKI treatment efficacy.

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Lucie Benesova Zbynek Bortlicek Marek Minarik

Anticancer Res 2013 Apr;33(4):1705-11

Department of Oncology and Radiotherapy, Medical School and Teaching Hospital Pilsen, Charles University, Prague, Czech Republic.

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April 2013

The dominant role of G12C over other KRAS mutation types in the negative prediction of efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer.

Authors:

Ondrej Fiala Milos Pesek Jindrich Finek Lucie Benesova Barbora Belsanova Marek Minarik

Cancer Genet 2013 Jan-Feb;206(1-2):26-31. Epub 2013 Jan 10.

Department of Oncology and Radiotherapy, Medical School and Teaching Hospital Pilsen, Charles University Prague, Czech Republic.

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April 2013

Lack of association between clopidogrel responsiveness tested using point-of-care assay and prognosis of patients with coronary artery disease.

Authors:

Petra Paulu Pavel Osmancik Petr Tousek Marek Minarik Lucie Benesova Zuzana Motovska Frantisek Bednar Viktor Kocka Petr Widimsky

J Thromb Thrombolysis 2013 Jul;36(1):1-6

Cardiocenter, 3rd internal-cardiology clinic, 3rd Medical School, Charles University and University Hospital Kralovske Vinohrady, Srobarova 50, 10034 Prague, Czech Republic.

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July 2013

Utility of cell-free tumour DNA for post-surgical follow-up of colorectal cancer patients.

Authors:

Miroslav Levy Lucie Benesova Ludmila Lipska Barbora Belsanova Petra Minarikova Gabriela Veprekova Miroslav Zavoral Marek Minarik

Anticancer Res 2012 May;32(5):1621-6

Department of Surgery, First Faculty of Medicine, Charles University Prague and Thomayer Hospital, Prague, Czech Republic.

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May 2012

Rapid testing of clopidogrel resistance by genotyping of CYP2C19 and CYP2C9 polymorphisms using denaturing on-chip capillary electrophoresis.

Authors:

Marek Minarik Marta Kopeckova Marcus Gassman Pavel Osmancik Lucie Benesova

Electrophoresis 2012 Apr;33(8):1306-10

Center for Applied Genomics of Solid Tumors, Genomac Research Institute, Prague, Czech Republic.

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April 2012

Spectrum and clinical manifestations of mutations in genes responsible for hypertrophic cardiomyopathy.

Authors:

Karol Curila Lucie Benesova Martin Penicka Marek Minarik David Zemanek Josef Veselka Petr Widimsky Pavel Gregor

Acta Cardiol 2012 Feb;67(1):23-9

Cardiocentre, Department of Cardiology, 3rd Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic.

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February 2012

Clinical significance of hypermethylation status in NSCLC: evaluation of a 30-gene panel in patients with advanced disease.

Authors:

Milos Pesek Marta Kopeckova Lucie Benesova Anna Meszarosova Petr Mukensnabl Frantisek Bruha Marek Minarik

Anticancer Res 2011 Dec;31(12):4647-52

Department of Pneumology, Faculty Hospital Pilsen, Pilsen, Czech Republic.

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December 2011

Molecular biology of pancreatic cancer.

Authors:

Miroslav Zavoral Petra Minarikova Filip Zavada Cyril Salek Marek Minarik

World J Gastroenterol 2011 Jun;17(24):2897-908

Charles University, 1st Medical Faculty, Internal Clinic, 128 00 Prague 2, Czech Republic.

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June 2011

A novel high-resolution chipCE assay for rapid detection of EGFR gene mutations and amplifications in lung cancer therapy by a combination of fragment analysis, denaturing CE and MLPA.

Authors:

Marek Minarik Marcus Gassman Barbora Belsanova Milos Pesek Jan Schouten Richard Chudoba Bohuslav Gas Lucie Benesova

Electrophoresis 2010 Oct;31(21):3518-24

Laboratory for Molecular Genetics and Oncology, Genomac International, Prague, Czech Republic.

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October 2010

Multiplicity of EGFR and KRAS mutations in non-small cell lung cancer (NSCLC) patients treated with tyrosine kinase inhibitors.

Authors:

Lucie Benesova Marek Minarik Dana Jancarikova Barbora Belsanova Milos Pesek

Anticancer Res 2010 May;30(5):1667-71

Laboratory for Molecular Genetics and Oncology, Genomac International, Ltd., Prague, Czech Republic.

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May 2010

Denaturing capillary electrophoresis for automated detection of L858R mutation in exon 21 of the epidermal growth factor receptor gene in prediction of the outcome of lung cancer therapy.

Authors:

Lucie Benesova Milos Pesek Barbora Belsanova Patrik Sekerka Marek Minarik

J Sep Sci 2010 Aug;33(15):2349-55

Laboratory for Molecular Genetics and Oncology, Genomac International, Ltd., Prague, Czech Republic.

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August 2010

Assembly of a large Y-STR haplotype database for the Czech population and investigation of its substructure.

Authors:

Jan Zastera Lutz Roewer Sascha Willuweit Patrik Sekerka Lucie Benesova Marek Minarik

Forensic Sci Int Genet 2010 Apr;4(3):e75-8

Laboratory for Molecular Genetics and Oncology, Genomac International, Ltd., Prague, Czech Republic.

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April 2010

Low prevalence and variable clinical presentation of troponin I and troponin T gene mutations in hypertrophic cardiomyopathy.

Authors:

Karol Curila Lucie Benesova Martin Penicka Marek Minarik David Zemanek Josef Veselka Petr Widimsky Pavel Gregor

Genet Test Mol Biomarkers 2009 Oct;13(5):647-50

Cardiocenter, Department of Cardiology, 3rd Faculty of Medicine, Charles University, and University Hospital Kralovske Vinohrady, Prague, Czech Republic.

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October 2009