Marcus W Bosenberg

Marcus W Bosenberg

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Marcus W Bosenberg

Marcus W Bosenberg

Publications by authors named "Marcus W Bosenberg"

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Patterns of immune-cell infiltration in murine models of melanoma: roles of antigen and tissue site in creating inflamed tumors.

Cancer Immunol Immunother 2019 Jul 27;68(7):1121-1132. Epub 2019 May 27.

Division of Surgical Oncology, Department of Surgery, University of Virginia, P. O. Box 800709, Charlottesville, VA, 22908-0709, USA.

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http://dx.doi.org/10.1007/s00262-019-02345-5DOI Listing
July 2019

Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting.

Cell Metab 2019 Jun 21;29(6):1410-1421.e4. Epub 2019 Mar 21.

Koch Institute for Integrative Cancer Research, Cambridge, MA, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute, Cambridge, MA 02139, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131193012
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http://dx.doi.org/10.1016/j.cmet.2019.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551255PMC
June 2019

PD-L1 methylation regulates PD-L1 expression and is associated with melanoma survival.

Pigment Cell Melanoma Res 2019 05 22;32(3):435-440. Epub 2018 Nov 22.

Department of Pathology, Yale School of Medicine, New Haven, Connecticut.

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http://doi.wiley.com/10.1111/pcmr.12745
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http://dx.doi.org/10.1111/pcmr.12745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475614PMC
May 2019

Immune Cell and Cell Cluster Phenotyping, Quantitation, and Visualization Using In Silico Multiplexed Images and Tissue Cytometry.

Cytometry A 2019 Apr 23;95(4):399-410. Epub 2018 Nov 23.

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1002/cyto.a.23668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500592PMC
April 2019

p90RSK Blockade Inhibits Dual BRAF and MEK Inhibitor-Resistant Melanoma by Targeting Protein Synthesis.

J Invest Dermatol 2017 10 7;137(10):2187-2196. Epub 2017 Jun 7.

Department of Pathology, Yale School of Medicine, New Haven, Connecticut, USA; Department of Dermatology, Yale School of Medicine, New Haven, Connecticut, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.12.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342201PMC
October 2017

Stem cell-released oncolytic herpes simplex virus has therapeutic efficacy in brain metastatic melanomas.

Proc Natl Acad Sci U S A 2017 07 14;114(30):E6157-E6165. Epub 2017 Jul 14.

Center for Stem Cell Therapeutics and Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114;

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http://dx.doi.org/10.1073/pnas.1700363114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544283PMC
July 2017

Attenuation of genome-wide 5-methylcytosine level is an epigenetic feature of cutaneous malignant melanomas.

Melanoma Res 2017 04;27(2):85-96

Departments of aPathology bDermatology, Yale University, New Haven, Connecticut Departments of cPathology dDermatology eOncology, The Johns Hopkins University School of Medicine fSidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/CMR.0000000000000315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812886PMC
April 2017

A Computational Approach for Identifying Synergistic Drug Combinations.

PLoS Comput Biol 2017 01 13;13(1):e1005308. Epub 2017 Jan 13.

Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1005308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234777PMC
January 2017

The YUMM lines: a series of congenic mouse melanoma cell lines with defined genetic alterations.

Pigment Cell Melanoma Res 2016 09 3;29(5):590-7. Epub 2016 Aug 3.

Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.

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http://doi.wiley.com/10.1111/pcmr.12498
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http://dx.doi.org/10.1111/pcmr.12498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331933PMC
September 2016

Keratoacanthoma Shares Driver Mutations with Cutaneous Squamous Cell Carcinoma.

J Invest Dermatol 2016 08 7;136(8):1737-1741. Epub 2016 Jun 7.

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.04.002DOI Listing
August 2016

Melanosis of the areola and nipple with an atypical pigment network.

Int J Dermatol 2016 Jul 28;55(7):811-813. Epub 2015 Jul 28.

Department of Dermatology, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1111/ijd.12898DOI Listing
July 2016

Cell and Tissue Display: An Alternative Multipurpose Tool for Microscopy.

J Histochem Cytochem 2016 07 7;64(7):403-11. Epub 2016 Jun 7.

Division of Dermatopathology, Department of Dermatology, Yale University, New Haven, Connecticut (NT, GM, MWB, NR)

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http://dx.doi.org/10.1369/0022155416651065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931762PMC
July 2016

Integrative discovery of CD98 as a melanoma biomarker.

Pigment Cell Melanoma Res 2016 May 10;29(3):385-7. Epub 2016 Apr 10.

Department of Dermatology, Division of Dermatopathology, Yale University, New Haven, CT, USA.

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http://dx.doi.org/10.1111/pcmr.12464DOI Listing
May 2016

PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.

Immunity 2016 05;44(5):1190-203

Infectious and Inflammatory Disease Center and NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Research Institute, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908967PMC
May 2016

Well-Differentiated Syringofibrocarcinoma in a Patient With Clouston Syndrome.

JAMA Dermatol 2016 Apr;152(4):484-6

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1001/jamadermatol.2015.4496DOI Listing
April 2016

What is a vertebrate pigment cell?

Pigment Cell Melanoma Res 2016 Jan 3;29(1):8-14. Epub 2015 Nov 3.

Department of Biology & Biochemistry and Centre for Regenerative Medicine, University of Bath, Claverton Down, Bath, UK.

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http://dx.doi.org/10.1111/pcmr.12409DOI Listing
January 2016

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

Cell 2015 Sep 27;162(6):1217-28. Epub 2015 Aug 27.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567953PMC
September 2015

BRAF Inhibition Decreases Cellular Glucose Uptake in Melanoma in Association with Reduction in Cell Volume.

Mol Cancer Ther 2015 Jul 6;14(7):1680-92. Epub 2015 May 6.

Department of Pathology, Yale School of Medicine, New Haven, Connecticut. Department of Dermatology, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497841PMC
July 2015

PLEKHA5 as a Biomarker and Potential Mediator of Melanoma Brain Metastasis.

Clin Cancer Res 2015 May 14;21(9):2138-47. Epub 2014 Oct 14.

Department of Medicine, Section of Medical Oncology, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397107PMC
May 2015

Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma.

Nat Genet 2015 May 13;47(5):486-95. Epub 2015 Apr 13.

1] Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, USA. [2] Institute of Molecular and Cell Biology, Singapore.

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http://dx.doi.org/10.1038/ng.3275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844184PMC
May 2015

BRAF inhibition alleviates immune suppression in murine autochthonous melanoma.

Cancer Immunol Res 2014 Nov 2;2(11):1044-50. Epub 2014 Sep 2.

Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Norris-Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.

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http://dx.doi.org/10.1158/2326-6066.CIR-14-0074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230697PMC
November 2014

Dendritic cell-derived interleukin-15 is crucial for therapeutic cancer vaccine potency.

Oncoimmunology 2014 Nov 15;3(10):e959321. Epub 2014 Dec 15.

Department of Dermatology; University of Pittsburgh School of Medicine ; Pittsburgh, PA USA ; Department of Immunology; University of Pittsburgh School of Medicine ; Pittsburgh, PA USA ; University of Pittsburgh Cancer Institute ; Pittsburgh, PA USA.

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http://dx.doi.org/10.4161/21624011.2014.959321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292719PMC
November 2014

Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ.

Cancer Res 2014 Jun 15;74(12):3205-17. Epub 2014 Apr 15.

Authors' Affiliations: Departments of Immunobiology, Dermatology, and Pathology, Yale University School of Medicine, New Haven, Connecticut; and Howard Hughes Medical Institute, Chevy Chase, MarylandAuthors' Affiliations: Departments of Immunobiology, Dermatology, and Pathology, Yale University School of Medicine, New Haven, Connecticut; and Howard Hughes Medical Institute, Chevy Chase, Maryland

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063281PMC
June 2014

Isolation and molecular characterization of circulating melanoma cells.

Cell Rep 2014 May 18;7(3):645-53. Epub 2014 Apr 18.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129, USA; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Howard Hughes Medical Institute, Bethesda, MD 20815, USA. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(14)00217-4.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471400217
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http://dx.doi.org/10.1016/j.celrep.2014.03.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079008PMC
May 2014

Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.

Proc Natl Acad Sci U S A 2013 Nov 21;110(45):18226-31. Epub 2013 Oct 21.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129.

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http://dx.doi.org/10.1073/pnas.1317577110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831456PMC
November 2013

Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma.

Proc Natl Acad Sci U S A 2013 Sep 3;110(38):E3640-9. Epub 2013 Sep 3.

Department of Genetics, Howard Hughes Medical Institute, and Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, CT 06510.

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http://dx.doi.org/10.1073/pnas.1314435110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780872PMC
September 2013

Vesicular stomatitis virus variants selectively infect and kill human melanomas but not normal melanocytes.

J Virol 2013 Jun 3;87(12):6644-59. Epub 2013 Apr 3.

Department of Neurosurgery, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.03311-12
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http://dx.doi.org/10.1128/JVI.03311-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676084PMC
June 2013

Perifollicular fibroma in Birt-Hogg-Dubé syndrome: an association revisited.

J Cutan Pathol 2012 Jul;39(7):675-9

Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1111/j.1600-0560.2012.01929.xDOI Listing
July 2012

Colonic ganglioneuromatous polyposis and metastatic adenocarcinoma in the setting of Cowden syndrome: a case report and literature review.

Hum Pathol 2012 Apr 21;43(4):601-4. Epub 2011 Oct 21.

Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1016/j.humpath.2011.06.022DOI Listing
April 2012

piggyBac transposon somatic mutagenesis with an activated reporter and tracker (PB-SMART) for genetic screens in mice.

PLoS One 2011 21;6(10):e26650. Epub 2011 Oct 21.

Department of Genetics, Yale University School of Medicine, Boyer Center for Molecular Medicine, Howard Hughes Medical Institute, New Haven, Connecticut, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026650PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198810PMC
February 2012

Investigative pathology: leading the post-genomic revolution.

Lab Invest 2012 Jan 10;92(1):4-8. Epub 2011 Oct 10.

Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1038/labinvest.2011.147DOI Listing
January 2012

Characterization of melanoma cells capable of propagating tumors from a single cell.

Cancer Res 2010 Jan;70(1):388-97

Department of Pathology, University of Vermont College of Medicine, Burlington, Vermont, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026296PMC
January 2010

Autoimmune acrosyringitis with ductal cysts: reclassification of case of eruptive syringoma.

J Cutan Pathol 2009 Dec 11;36(12):1312-5. Epub 2009 Jun 11.

Pathology, University of Utah Health Sciences, Department of Pathology, Division of Anatomic Pathology, Huntsman Cancer Hospital, Room 3860, Salt Lake City, Utah 84112, USA.

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http://dx.doi.org/10.1111/j.1600-0560.2009.01277.xDOI Listing
December 2009

Melanotic schwannoma arising in association with nevus of Ota: 2 cases suggesting a shared mechanism.

Am J Dermatopathol 2009 Dec;31(8):808-13

Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1097/DAD.0b013e3181accd0eDOI Listing
December 2009

LKB1 deficiency sensitizes mice to carcinogen-induced tumorigenesis.

Cancer Res 2008 Jan;68(1):55-63

Massachusetts General Hospital, Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-3225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739055PMC
January 2008

Loss of xeroderma pigmentosum C (Xpc) enhances melanoma photocarcinogenesis in Ink4a-Arf-deficient mice.

Cancer Res 2007 Jun;67(12):5649-57

Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3806DOI Listing
June 2007

Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse.

Proc Natl Acad Sci U S A 2007 Mar 27;104(10):3931-6. Epub 2007 Feb 27.

Department of Medical Oncology, Belfer Foundation Institute for Innovative Cancer Science, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0700093104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820686PMC
March 2007

Precancer in mice: animal models used to understand, prevent, and treat human precancers.

Toxicol Pathol 2006 ;34(6):699-707

The UCD Center for Comparative Medicine, University of California, Davis, Davis, California 95616, USA.

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http://dx.doi.org/10.1080/01926230600930129DOI Listing
January 2007

Amplification of CDK4 and MDM2 in malignant melanoma.

Genes Chromosomes Cancer 2006 May;45(5):447-54

Department of Pathology, University of Vermont, Burlington, Vermont 05495, USA.

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http://dx.doi.org/10.1002/gcc.20310DOI Listing
May 2006

Role of epidermal growth factor receptor signaling in RAS-driven melanoma.

Mol Cell Biol 2005 May;25(10):4176-88

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1128/MCB.25.10.4176-4188.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087708PMC
May 2005

Pleomorphic liposarcoma: clinicopathologic analysis of 57 cases.

Am J Surg Pathol 2004 Oct;28(10):1257-67

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1097/01.pas.0000135524.73447.4aDOI Listing
October 2004

Deregulated Akt3 activity promotes development of malignant melanoma.

Cancer Res 2004 Oct;64(19):7002-10

Department of Pharmacology, The Pennsylvania State College of Medicine, Hershey, Pennsylvania 17033, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-1399DOI Listing
October 2004

Mouse models of human cancers (part 3).

Comp Med 2004 Jun;54(3):258-70

Center for Comparative Medicine, University of California-Davis, 95615, USA.

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June 2004

Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice.

Proc Natl Acad Sci U S A 2002 Feb 29;99(3):1455-60. Epub 2002 Jan 29.

Department of Adult Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.022632099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC122212PMC
February 2002