Marcus M Seldin

Marcus M Seldin

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Marcus M Seldin

Marcus M Seldin

Publications by authors named "Marcus M Seldin"

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Sex-specific metabolic functions of adipose Lipocalin-2.

Mol Metab 2019 12 27;30:30-47. Epub 2019 Sep 27.

Department of Medicine/Division of Cardiology, University of California, Los Angeles, CA, USA; Department of Human Genetics, University of California, Los Angeles, CA, USA; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812340PMC
December 2019

Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism.

Mol Metab 2019 06 14;24:44-63. Epub 2019 Mar 14.

Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531814PMC
June 2019

Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits.

Cell Metab 2019 04 10;29(4):932-949.e4. Epub 2019 Jan 10.

Department of Medicine/Division of Cardiology and Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447452PMC
April 2019

Systems-based approaches for investigation of inter-tissue communication.

J Lipid Res 2019 Mar 7;60(3):450-455. Epub 2019 Jan 7.

Departments of Medicine, University of California, Los Angeles, Los Angeles, CA 90095

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http://dx.doi.org/10.1194/jlr.S090316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399495PMC
March 2019

Transcription Factor Zhx2 Deficiency Reduces Atherosclerosis and Promotes Macrophage Apoptosis in Mice.

Arterioscler Thromb Vasc Biol 2018 09;38(9):2016-2027

From the Department of Medicine, David Geffen School of Medicine (A.E., M.M.S., X.W., M.M., Z.Z., H.Q., K.S.D., R.R.S., S.S., A.J.L.).

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http://dx.doi.org/10.1161/ATVBAHA.118.311266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202168PMC
September 2018

A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism.

Cell Metab 2018 May;27(5):1138-1155.e6

Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935137PMC
May 2018

IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure.

Cell 2018 01 14;172(1-2):218-233.e17. Epub 2017 Dec 14.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766418PMC
January 2018

Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease.

Cell Syst 2018 Jan 18;6(1):103-115.e7. Epub 2018 Jan 18.

Department of Integrative Biology and Physiology, University of California, Los Angeles, CA, USA; Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2017.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799036PMC
January 2018

C1q/TNF-related protein 6 (CTRP6) links obesity to adipose tissue inflammation and insulin resistance.

J Biol Chem 2017 09 18;292(36):14836-14850. Epub 2017 Jul 18.

From the Department of Physiology and Center for Metabolism and Obesity Research, School of Medicine, The Johns Hopkins University, Baltimore, Maryland 21205 and

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http://dx.doi.org/10.1074/jbc.M116.766808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592665PMC
September 2017

A systems genetics approach identifies as a link between cardiomyocyte glucose utilization and hypertrophic response.

Am J Physiol Heart Circ Physiol 2017 Apr 24;312(4):H728-H741. Epub 2017 Feb 24.

Department of Medicine, Cardiology Division at the University of California Los Angeles, Los Angeles, California; and

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http://dx.doi.org/10.1152/ajpheart.00068.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407157PMC
April 2017

Expression of the Astrocyte Water Channel Aquaporin-4 in the Mouse Brain.

ASN Neuro 2015 Sep-Oct;7(5). Epub 2015 Oct 21.

Center for Glial-Neuronal Interactions, Division of Biomedical Sciences, University of California, Riverside, CA, USA

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http://journals.sagepub.com/doi/10.1177/1759091415605486
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http://dx.doi.org/10.1177/1759091415605486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623559PMC
June 2016

Loss of CTRP5 improves insulin action and hepatic steatosis.

Am J Physiol Endocrinol Metab 2016 06 3;310(11):E1036-52. Epub 2016 May 3.

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, Maryland

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http://dx.doi.org/10.1152/ajpendo.00010.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935138PMC
June 2016

Thromboxane synthase deficiency improves insulin action and attenuates adipose tissue fibrosis.

Am J Physiol Endocrinol Metab 2015 May 3;308(9):E792-804. Epub 2015 Mar 3.

Department of Physiology and Center for Metabolism and Obesity Research, The Johns Hopkins University School of Medicine, Baltimore, Maryland;

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http://ajpendo.physiology.org/content/ajpendo/308/9/E792.ful
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http://ajpendo.physiology.org/content/ajpendo/early/2015/03/
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http://ajpendo.physiology.org/lookup/doi/10.1152/ajpendo.003
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http://dx.doi.org/10.1152/ajpendo.00383.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420899PMC
May 2015

Dynamic Visualization of mTORC1 Activity in Living Cells.

Cell Rep 2015 Mar 12;10(10):1767-1777. Epub 2015 Mar 12.

Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.02.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567530PMC
March 2015

CTRP2 overexpression improves insulin and lipid tolerance in diet-induced obese mice.

PLoS One 2014 20;9(2):e88535. Epub 2014 Feb 20.

Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America ; Center for Metabolism and Obesity Research, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088535PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930646PMC
January 2015

Mouse-human experimental epigenetic analysis unmasks dietary targets and genetic liability for diabetic phenotypes.

Cell Metab 2015 Jan;21(1):138-49

Department of Medicine, Johns Hopkins University School of Medicine, 855 North Wolfe Street, Baltimore, MD 21205, USA; Center for Epigenetics, Johns Hopkins University School of Medicine, 855 North Wolfe Street, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2014.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340475PMC
January 2015

Dynamic and extensive metabolic state-dependent regulation of cytokine expression and circulating levels.

Am J Physiol Regul Integr Comp Physiol 2014 Dec 15;307(12):R1458-70. Epub 2014 Oct 15.

Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland; Center for Metabolism and Obesity Research, The Johns Hopkins University School of Medicine, Baltimore, Maryland

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http://dx.doi.org/10.1152/ajpregu.00335.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269668PMC
December 2014

Metabolic function of the CTRP family of hormones.

Rev Endocr Metab Disord 2014 Jun;15(2):111-23

Department of Physiology and Center for Metabolism and Obesity Research, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1007/s11154-013-9255-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931758PMC
June 2014

Skeletal muscle-derived myonectin activates the mammalian target of rapamycin (mTOR) pathway to suppress autophagy in liver.

J Biol Chem 2013 Dec 1;288(50):36073-82. Epub 2013 Nov 1.

From the Department of Physiology and Center for Metabolism and Obesity Research, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M113.500736
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http://dx.doi.org/10.1074/jbc.M113.500736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861655PMC
December 2013

A central role for C1q/TNF-related protein 13 (CTRP13) in modulating food intake and body weight.

PLoS One 2013 25;8(4):e62862. Epub 2013 Apr 25.

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062862PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636217PMC
November 2013

CTRP9 transgenic mice are protected from diet-induced obesity and metabolic dysfunction.

Am J Physiol Regul Integr Comp Physiol 2013 Sep 10;305(5):R522-33. Epub 2013 Jul 10.

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1152/ajpregu.00110.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763026PMC
September 2013

CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism.

Am J Physiol Gastrointest Liver Physiol 2013 Aug 6;305(3):G214-24. Epub 2013 Jun 6.

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1152/ajpgi.00102.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742855PMC
August 2013

C1q/tumor necrosis factor-related protein 11 (CTRP11), a novel adipose stroma-derived regulator of adipogenesis.

J Biol Chem 2013 Apr 28;288(15):10214-29. Epub 2013 Feb 28.

Department of Physiology and Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M113.458711
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http://dx.doi.org/10.1074/jbc.M113.458711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624406PMC
April 2013

Endopeptidase cleavage generates a functionally distinct isoform of C1q/tumor necrosis factor-related protein-12 (CTRP12) with an altered oligomeric state and signaling specificity.

J Biol Chem 2012 Oct 31;287(43):35804-14. Epub 2012 Aug 31.

Department of Physiology and Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1074/jbc.M112.365965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476250PMC
October 2012

Regulation of tissue crosstalk by skeletal muscle-derived myonectin and other myokines.

Adipocyte 2012 Oct;1(4):200-202

Department of Physiology and Center for Metabolism and Obesity Research; The Johns Hopkins University School of Medicine; Baltimore, MD USA.

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http://dx.doi.org/10.4161/adip.20877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609113PMC
October 2012

Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis.

Exp Neurol 2012 May 14;235(1):246-55. Epub 2012 Feb 14.

Department of Neurological Surgery, University of California, Davis, CA, USA.

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http://dx.doi.org/10.1016/j.expneurol.2012.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334411PMC
May 2012

Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis.

J Biol Chem 2012 Apr 17;287(15):11968-80. Epub 2012 Feb 17.

Department of Physiology and Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1074/jbc.M111.336834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320944PMC
April 2012

Aquaporin-4-dependent edema clearance following status epilepticus.

Epilepsy Res 2012 Feb 12;98(2-3):264-8. Epub 2011 Oct 12.

Department of Neurological Surgery, University of California, Davis, CA, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S09201211110028
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http://dx.doi.org/10.1016/j.eplepsyres.2011.09.016DOI Listing
February 2012