Publications by authors named "Marcus Hacker"

100Publications

Synthesis, Biological, and Computational Evaluation of Antagonistic, Chiral Hydrobenzoin Esters of Arecaidine Targeting mAChR M1.

Pharmaceuticals (Basel) 2020 Nov 30;13(12). Epub 2020 Nov 30.

Department of Pharmaceutical Chemistry, Faculty of Life Sciences, University of Vienna, 1090 Vienna, Austria.

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November 2020

Comparison of PET imaging of activated fibroblasts and F-FDG for diagnosis of primary hepatic tumours: a prospective pilot study.

Eur J Nucl Med Mol Imaging 2020 Oct 24. Epub 2020 Oct 24.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

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October 2020

Assessment of left and right ventricular functional parameters using dynamic dual-tracer [N]NH3 and [F]FDG PET/MRI.

J Nucl Cardiol 2020 Oct 22. Epub 2020 Oct 22.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, Floor 5L, 1090, Vienna, Austria.

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October 2020

Immune Checkpoint Inhibitor Therapy Induces Inflammatory Activity in Large Arteries.

Circulation 2020 Dec 8;142(24):2396-2398. Epub 2020 Sep 8.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy (R.C., V.P., M.M., G.K., A.H., X.L., M.H.).

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December 2020

Enhanced arecoline derivatives as muscarinic acetylcholine receptor M1 ligands for potential application as PET radiotracers.

Eur J Med Chem 2020 Oct 19;204:112623. Epub 2020 Jul 19.

Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Austria. Electronic address:

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October 2020

Accuracy of PET quantification in [Ga]Ga-pentixafor PET/MR imaging of carotid plaques.

J Nucl Cardiol 2020 Jul 21. Epub 2020 Jul 21.

QIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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July 2020

Assessment of cerebral glucose metabolism in patients with heart failure by F-FDG PET/CT imaging.

J Nucl Cardiol 2020 Jul 20. Epub 2020 Jul 20.

Department of Nuclear Medicine, Laboratory for Molecular Imaging, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

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July 2020

In Human Visualization of Ibrutinib-Induced CLL Compartment Shift.

Cancer Immunol Res 2020 08 24;8(8):984-989. Epub 2020 Jun 24.

Division of Hematology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

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August 2020

Detection of aortic prosthetic graft infection with F-FDG PET/CT imaging, concordance with consensus MAGIC graft infection criteria.

J Nucl Cardiol 2020 Jun 17. Epub 2020 Jun 17.

Department of Nuclear Medicine, Laboratory for Molecular Imaging, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.

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June 2020

Sorbitol as a Polar Pharmacological Modifier to Enhance the Hydrophilicity of Tc-Tricarbonyl-Based Radiopharmaceuticals.

Molecules 2020 Jun 9;25(11). Epub 2020 Jun 9.

Ludwig Boltzmann Institute Applied Diagnostics, General Hospital of Vienna, c/o Sekretariat Nuklearmedizin, Währiger Gürtel 18-20, 1090 Vienna, Austria.

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June 2020

Fibroblast imaging of hepatic carcinoma with Ga-FAPI-04 PET/CT: a pilot study in patients with suspected hepatic nodules.

Eur J Nucl Med Mol Imaging 2020 May 29. Epub 2020 May 29.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

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May 2020

Dynamic 2-deoxy-2[18F] fluoro-D-glucose PET/MRI in human renal allotransplant patients undergoing acute kidney injury.

Sci Rep 2020 05 19;10(1):8270. Epub 2020 May 19.

Department of Biomedical Imaging and Image- Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna. Waehringer Guertel 18-20, 1090, Vienna, Austria.

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May 2020

Applied Systems Biology-embracing molecular imaging for systemic medicine.

Eur J Nucl Med Mol Imaging 2020 Nov;47(12):2721-2725

QIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Lazarettgasse 14, 1090, Vienna, Austria.

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November 2020

Imaging CXCR4 expression in patients with suspected primary hyperaldosteronism.

Eur J Nucl Med Mol Imaging 2020 Oct 23;47(11):2656-2665. Epub 2020 Mar 23.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

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October 2020

Left-ventricular innervation assessed by I-SPECT/CT is associated with cardiac events in inherited arrhythmia syndromes.

Int J Cardiol 2020 08 6;312:129-135. Epub 2020 Mar 6.

Department of Cardiology and Vascular Medicine, West-German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany; Department of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany; German Cardiovascular Research Center (DZHK), Munich Heart Alliance, Munich, Germany. Electronic address:

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August 2020

Determinants of the intercept and slope of glomerular filtration rate in recipients of a live donor kidney transplant.

Wien Klin Wochenschr 2020 Feb 3. Epub 2020 Feb 3.

Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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February 2020

Assessment of cardiac tumors by F-FDG PET/CT imaging: Histological correlation and clinical outcomes.

J Nucl Cardiol 2020 Jan 13. Epub 2020 Jan 13.

Division of Nuclear Medicine, Department of Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.

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January 2020

Comparison of different kinetic models for dynamic F-FDG PET/CT imaging of hepatocellular carcinoma with various, also dual-blood input function.

Phys Med Biol 2020 02 10;65(4):045001. Epub 2020 Feb 10.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria. Both authors contributed equally to this work.

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February 2020

Pitfalls and solutions of the fully-automated radiosynthesis of [C]metoclopramide.

EJNMMI Radiopharm Chem 2019 Dec 18;4(1):31. Epub 2019 Dec 18.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

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December 2019

Clinical outcome of standardized Lu-PSMA-617 therapy in metastatic prostate cancer patients receiving 7400 MBq every 4 weeks.

Eur J Nucl Med Mol Imaging 2020 03 28;47(3):713-720. Epub 2019 Nov 28.

Department of Biomedical Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.

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March 2020

Toward the Optimization of (+)-[C]PHNO Synthesis: Time Reduction and Process Validation.

Contrast Media Mol Imaging 2019 30;2019:4292596. Epub 2019 Sep 30.

Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.

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July 2020

Brain glucose uptake during transcranial direct current stimulation measured with functional [F]FDG-PET.

Brain Imaging Behav 2020 Apr;14(2):477-484

Neuroimaging Labs (NIL) - PET & MRI & EEG & Chemical Lab, Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.

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April 2020

Attenuation correction of a flat table top for radiation therapy in hybrid PET/MR using CT- and Ge/Ga transmission scan-based μ-maps.

Phys Med 2019 Sep 19;65:76-83. Epub 2019 Aug 19.

Department of Radiotherapy, Comprehensive Cancer Center, Medical University of Vienna, Währingergürtel 18-20, 1090 Vienna, Austria; Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna, Währingergürtel 18-20, 1090 Vienna, Austria. Electronic address:

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September 2019

(R)-[F]NEBIFQUINIDE: A promising new PET tracer for TSPO imaging.

Eur J Med Chem 2019 Aug 10;176:410-418. Epub 2019 May 10.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria; Ludwig Boltzmann Institute Applied Diagnostics, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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August 2019

Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941.

J Vis Exp 2019 04 28(146). Epub 2019 Apr 28.

Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna.

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April 2019

Assessment of Myocardial Viability in Ischemic Heart Disease by PET/MRI: Comparison of Left Ventricular Perfusion, Hibernation, and Scar Burden.

Acad Radiol 2020 02 30;27(2):188-197. Epub 2019 Apr 30.

Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Gürtel 18-20, 1090 Vienna, Austria. Electronic address:

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February 2020

[Ga]Pentixafor PET/MR imaging of chemokine receptor 4 expression in the human carotid artery.

Eur J Nucl Med Mol Imaging 2019 Jul 19;46(8):1616-1625. Epub 2019 Apr 19.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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July 2019

Assessment of sympathetic reinnervation after cardiac transplantation using hybrid cardiac PET/MRI: A pilot study.

J Magn Reson Imaging 2019 10 20;50(4):1326-1335. Epub 2019 Mar 20.

Department of Biomedical Imaging and Image-Guided Therapy, Division of Cardiovascular and Interventional Radiology, Medical University of Vienna, Vienna, Austria.

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October 2019

Synthesis and in vitro evaluation of new translocator protein ligands designed for positron emission tomography.

Future Med Chem 2019 03 19;11(6):539-550. Epub 2019 Mar 19.

Division of Nuclear Medicine, Department of Biomedical Imaging & Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

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March 2019

FDG-PET/MRI imaging for the management of alveolar echinococcosis: initial clinical experience at a reference centre in Austria.

Trop Med Int Health 2019 06 27;24(6):663-670. Epub 2019 Mar 27.

Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.

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June 2019

Data-driven, projection-based respiratory motion compensation of PET data for cardiac PET/CT and PET/MR imaging.

J Nucl Cardiol 2020 12 13;27(6):2216-2230. Epub 2019 Feb 13.

QIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.

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December 2020

Binding Affinity of Some Endogenous and Synthetic TSPO Ligands Regarding the rs6971 Polymorphism.

Int J Mol Sci 2019 Jan 29;20(3). Epub 2019 Jan 29.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, 1090 Vienna, Austria.

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January 2019

Optimization of the Automated Synthesis of [11C]mHED-Administered and Apparent Molar Activities.

Pharmaceuticals (Basel) 2019 Jan 14;12(1). Epub 2019 Jan 14.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, 1090Vienna, Austria.

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January 2019

Dynamic [18F]FET-PET/MRI using standard MRI-based attenuation correction methods.

Eur Radiol 2019 Aug 11;29(8):4276-4285. Epub 2019 Jan 11.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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August 2019

Optimized Feature Extraction for Radiomics Analysis of F-FDG PET Imaging.

J Nucl Med 2019 06 2;60(6):864-872. Epub 2018 Nov 2.

QIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria; and.

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June 2019

Prognostic analysis of interim F-FDG PET/CT in patients with diffuse large B cell lymphoma after one cycle versus two cycles of chemotherapy.

Eur J Nucl Med Mol Imaging 2019 02 31;46(2):478-488. Epub 2018 Oct 31.

Department of Nuclear Medicine, First Hospital of Shanxi Medical University, No. 85, Jiefang Road, Taiyuan, 030001, Shanxi, China.

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February 2019

Molar activity - The keystone in C-radiochemistry: An explorative study using the gas phase method.

Nucl Med Biol 2018 12 12;67:21-26. Epub 2018 Oct 12.

Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria; CBmed GmbH - Center for Biomarker Research in Medicine, Graz, Austria.

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December 2018

Development and evaluation of a rapid analysis for HEPES determination in Ga-radiotracers.

EJNMMI Res 2018 Oct 23;8(1):95. Epub 2018 Oct 23.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.

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October 2018

L-[S-methyl-C]methionine - An example of radiosynthetic optimization.

Appl Radiat Isot 2018 Nov 29;141:107-111. Epub 2018 Aug 29.

Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria; CBmed GmbH - Center for Biomarker Research in Medicine, Graz, Austria.

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November 2018

Sodium-fluoride PET-CT for the non-invasive evaluation of coronary plaques in symptomatic patients with coronary artery disease: a cross-correlation study with intravascular ultrasound.

Eur J Nucl Med Mol Imaging 2018 11 31;45(12):2181-2189. Epub 2018 Aug 31.

Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Molecular Imaging Precision Medical Collaborative Innovation Center, Taiyuan, 030001, Shanxi Province, China.

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November 2018

Appearances are often deceptive.

Nuklearmedizin 2018 08 20;57(4):168. Epub 2018 Aug 20.

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August 2018

The prognostic value of [I]-vascular endothelial growth factor ([I]-VEGF) in glioma.

Eur J Nucl Med Mol Imaging 2018 12 30;45(13):2396-2403. Epub 2018 Jul 30.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

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December 2018

SNAPshots of the MCHR1: a Comparison Between the PET-Tracers [F]FE@SNAP and [C]SNAP-7941.

Mol Imaging Biol 2019 04;21(2):257-268

Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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April 2019

Comparison of fully-automated radiosyntheses of [C]erlotinib for preclinical and clinical use starting from in target produced [C]CO or [C]CH.

EJNMMI Radiopharm Chem 2018 30;3(1). Epub 2018 May 30.

1Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.

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May 2018

Molecular imaging and molecular diagnostics: two sides of the same coin?

Eur J Nucl Med Mol Imaging 2018 09;45(10):1645-1648

CBMed Core Lab2, Medical University of Vienna, Vienna, Austria.

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September 2018

Recommendations on nuclear and multimodality imaging in IE and CIED infections.

Eur J Nucl Med Mol Imaging 2018 09 24;45(10):1795-1815. Epub 2018 May 24.

Aix-Marseille University, URMITE, Aix Marseille Université, UM63, CNRS 7278, IRD 198, INSERM 1095- IHU - Méditerranée Infection, Marseille, France.

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September 2018

[F]DOPA PET/ceCT in diagnosis and staging of primary medullary thyroid carcinoma prior to surgery.

Eur J Nucl Med Mol Imaging 2018 11 15;45(12):2159-2169. Epub 2018 May 15.

Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer-Guertel 18-20, A-1090, Vienna, Austria.

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November 2018

Assessing the kidney function parameters glomerular filtration rate and effective renal plasma flow with dynamic FDG-PET/MRI in healthy subjects.

EJNMMI Res 2018 May 9;8(1):37. Epub 2018 May 9.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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May 2018

Microfluidic Ga-labeling: a proof of principle study.

Dalton Trans 2018 May;47(17):5997-6004

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

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May 2018

Analysis of hematological parameters as prognostic markers for toxicity and survival of Radium treatment.

Oncotarget 2018 Mar 5;9(22):16197-16204. Epub 2018 Mar 5.

Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.

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March 2018